John Prins

Sex Differences in the Risk of Barrett's Esophagus Associated With the Metabolic Effects of Obesity

Bradley J Kendall, Graeme A Macdonald, Johannes B Prins, Suzanne O'Brien, Aaron P Thrift, David C Whiteman

Journal article  |  2020  |  JOURNAL OF CLINICAL GASTROENTEROLOGY

GOAL: The goal of this study was to determine if there is an association between the insulin-insulin-like growth factor axis, the ..

Whole genome investigation of an atypical autism case identifies a novel ANOS1 mutation with subsequent diagnosis of Kallmann syndrome

Paul A Dawson, Soohyun Lee, Adam D Ewing, Johannes B Prins, Helen S Heussler

Journal article  |  2020  |  MOLECULAR GENETICS AND METABOLISM REPORTS

We report an actionable secondary finding from whole-genome sequencing (WGS) of a 10-year-old boy with autism. WGS identified non-..

The effect of glucocorticoids on Thrombospondin-1, Osteocalcin and the Thrombospondin-1:Osteocalcin ratio in humans

Nicole Cesana-Nigro, Sahar Keshvari, Johanna L Barclay, Jane Sorbello, John W Upham, Helen Benham, Stephen T Anderson, Natasha Steiger, Johannes B Prins, Warrick J Inder

Journal article  |  2019  |  CLINICAL ENDOCRINOLOGY

OBJECTIVE: Thrombospondin-1 (TSP1), a matricellular protein, and Osteocalcin (OCN), a noncollagenous protein secreted by osteoblas..

The independent effects of dietary energy restriction and circuit exercise training on fat oxidation in patients with NAFLD

Ilaria Croci, Nuala M Byrne, Veronique S Chachay, Andrew P Hills, Andrew D Clouston, Trisha M O’Moore-Sullivan, Johannes B Prins, Graeme A Macdonald, Ingrid J Hickman

Journal article  |  2019  |  Obesity Research & Clinical Practice

Diabetes screen during tuberculosis contact investigations highlights opportunity for new diabetes diagnosis and reveals metabolic differences between ethnic groups

Blanca Restrepo, Leanie Kleynhans, Alejandra B Salinas, Bassent Abdelbary, Happy Tshivhula, Genesis P Aguillon-Duran, Carine Kunsevi-Kilola, Gloria Salinas, Kim Stanley, Stephanus T Malherbe, Elizna Maasdorp, Moncerrato Garcia-Viveros, Ilze Louw, Esperanza M Garcia-Oropesa, Juan Carlos Lopez-Alvarenga, John B Prins, Gerhard Walzl, Larry S Schlesinger, Katharina Ronacher

Journal article  |  2018  |  TUBERCULOSIS

Type 2 diabetes (T2D) is a prevalent risk factor for tuberculosis (TB), but most studies on TB-T2D have focused on TB patients, be..

Biosimilarity and Interchangeability: Principles and Evidence: A Systematic Review

Ross A McKinnon, Matthew Cook, Winston Liauw, Mona Marabani, Ian C Marschner, Nicolle H Packer, Johannes B Prins

Journal article  |  2018  |  BIODRUGS

BACKGROUND: The efficacy, safety and immunogenicity risk of switching between an originator biologic and a biosimilar or from one ..

Gene networks associated with non-syndromic intellectual disability

Soohyun Lee, Stephen Rudd, Jacob Gratten, Peter M Visscher, Johannes B Prins, Paul A Dawson

Journal article  |  2018  |  JOURNAL OF NEUROGENETICS

Non-syndromic intellectual disability (NS-ID) is a genetically heterogeneous disorder, with more than 200 candidate genes to date...

Uniting emergency and inpatient clinicians across the ED-inpatient interface: The last frontier?

Andrew Staib, Clair Sullivan, Johannes B Prins, Andrew Burton-Jones, Gerry Fitzgerald, Ian Scott

Journal article  |  2017  |  EMERGENCY MEDICINE AUSTRALASIA

Unwell patients in the ED requiring inpatient admission must negotiate the interface between the ED and inpatient wards. Despite i..

Association of Sun Exposure, Skin Colour and Body Mass Index with Vitamin D Status in Individuals Who Are Morbidly Obese

Clare F Dix, Judith D Bauer, Ian Martin, Sharon Rochester, Briony Duarte Romero, Johannes B Prins, Olivia RL Wright

Journal article  |  2017  |  NUTRIENTS

Vitamin D deficiency is a common issue, particularly in obese populations, and is tested by assessing serum 25(OH)D concentrations..

Intensity of early correction of hyperglycaemia and outcome of critically ill patients with diabetic ketoacidosis

Johan Martensson, Michael Bailey, Balasubramanian Venkatesh, David Pilcher, Adam Deane, Yasmine Ali Abdelhamid, Marco Crisman, Brij Verma, Christopher MacIsaac, Geoffrey Wigmore, Yahya Shehabi, Takafumi Suzuki, Craig French, Neil Orford, Nima Kakho, Johannes Prins, Elif I Ekinci, Rinaldo Bellomo

Journal article  |  2017  |  CRITICAL CARE AND RESUSCITATION

OBJECTIVES: To determine the impact of the intensity of early correction of hyperglycaemia on outcomes in patients with diabetic k..