Julie Simpson

Parasite-Host Dynamics throughout Antimalarial Drug Development Stages Complicate the Translation of Parasite Clearance

Lydia Burgert, Sophie Zaloumis, Saber Dini, Louise Marquart, Pengxing Cao, Mohammed Cherkaoui, Nathalie Gobeau, James McCarthy, Julie A Simpson, Jorg J Mohrle, Melissa A Penny

Journal article  |  2021  |  Antimicrobial Agents and Chemotherapy

Ensuring continued success against malaria depends on a pipeline of new antimalarials. Antimalarial drug development utilizes prec..

Burden of soil-transmitted helminth infection in pregnant refugees and migrants on the Thailand-Myanmar border: Results from a retrospective cohort

Tobias Brummaier, Nay Win Tun, Aung Myat Min, Mary Ellen Gilder, Laypaw Archasuksan, Stephane Proux, Douwe Kiestra, Prakaykaew Charunwatthana, Juerg Utzinger, Daniel H Paris, Mathieu Nacher, Julie A Simpson, Francois Nosten, Rose McGready

Journal article  |  2021  |  PLOS Neglected Tropical Diseases

BACKGROUND: Soil-transmitted helminth (STH) infections are widespread in tropical and subtropical regions. While many STH infectio..

A scoping review of studies using observational data to optimise dynamic treatment regimens

Robert K Mahar, Myra B McGuinness, Bibhas Chakraborty, John B Carlin, Maarten J IJzerman, Julie A Simpson

Journal article  |  2021  |  BMC Medical Research Methodology

BACKGROUND: Dynamic treatment regimens (DTRs) formalise the multi-stage and dynamic decision problems that clinicians often face w..

Study design, rationale and methods of the Revitalising Informal Settlements and their Environments (RISE) study: a cluster randomised controlled trial to evaluate environmental and human health impacts of a water-sensitive intervention in informal settlements in Indonesia and Fiji

Karin Leder, John J Openshaw, Pascale Allotey, Ansariadi Ansariadi, S Fiona Barker, Kerrie Burge, Thomas F Clasen, Steven L Chown, Grant A Duffy, Peter A Faber, Genie Fleming, Andrew B Forbes, Matthew French, Chris Greening, Rebekah Henry, Ellen Higginson, David W Johnston, Rachael Lappan, Audrie Lin, Stephen P Luby, et al.

Journal article  |  2021  |  BMJ Open

INTRODUCTION: Increasing urban populations have led to the growth of informal settlements, with contaminated environments linked t..

Sample pooling is a viable strategy for SARS-CoV-2 detection in low-prevalence settings

Brian SW Chong, Thomas Tran, Julian Druce, Susan A Ballard, Julie A Simpson, Mike Catton

Journal article  |  2020  |  Pathology

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has significantly increased demand on laboratory through..

The risk of adverse clinical outcomes following treatment of Plasmodium vivax malaria with and without primaquine in Papua, Indonesia

Kamala Thriemer, Jeanne-Rini Poespoprodjo, Enny Kenangalem, Nicholas M Douglas, Paulus Sugiarto, Nicholas M Anstey, Julie Anne Simpson, Ric N Price

Journal article  |  2020  |  PLoS Neglected Tropical Diseases

The widespread use of primaquine (PQ) radical cure for P. vivax, is constrained by concerns over its safety. We used routinely col..

Multiple imputation methods for handling missing values in longitudinal studies with sampling weights: Comparison of methods implemented in Stata

Anurika P De Silva, Alysha M De Livera, Katherine J Lee, Margarita Moreno-Betancur, Julie A Simpson

Journal article  |  2020  |  Biometrical Journal

Many analyses of longitudinal cohorts require incorporating sampling weights to account for unequal sampling probabilities of part..

Estimating the Proportion of Plasmodium vivax Recurrences Caused by Relapse: A Systematic Review and Meta-Analysis

Robert J Commons, Julie A Simpson, James Watson, Nicholas J White, Ric N Price

Journal article  |  2020  |  American Journal of Tropical Medicine and Hygiene

Plasmodium vivax and Plasmodium ovale form dormant liver hypnozoites that can reactivate weeks to months following initial infecti..

Evaluation of the effectiveness of topical repellent distributed by village health volunteer networks against Plasmodium spp. infection in Myanmar: A stepped-wedge cluster randomised trial

Paul A Agius, Julia C Cutts, Win Han Oo, Aung Thi, Katherine O'Flaherty, Kyaw Zayar Aung, Htin Kyaw Thu, Poe Poe Aung, Myat Mon Thein, Nyi Nyi Zaw, Wai Yan Min Htay, Aung Paing Soe, Zahra Razook, Alyssa E Barry, Win Htike, Angela Devine, Julie A Simpson, Brendan S Crabb, James G Beeson, Naanki Pasricha, et al.

Journal article  |  2020  |  PLoS Medicine

BACKGROUND: The World Health Organization has yet to endorse deployment of topical repellents for malaria prevention as part of pu..

Identifying and combating the impacts of COVID-19 on malaria

Stephen J Rogerson, James G Beeson, Moses Laman, Jeanne Rini Poespoprodjo, Timothy William, Julie A Simpson, Ric N Price

Journal article  |  2020  |  BMC MEDICINE

BACKGROUND: The COVID-19 pandemic has resulted in millions of infections, hundreds of thousands of deaths and major societal disru..