Rachel Wong

Immunohistochemical evaluation of the prognostic and predictive power of epidermal growth factor receptor ligand levels in patients with metastatic colorectal cancer

Siavash Foroughi, Ryan A Hutchinson, Hui-li Wong, Michael Christie, Ahida Batrouney, Rachel Wong, Margaret Lee, Jeanne Tie, Antony Wilks Burgess, Peter Gibbs

Journal article  |  2021  |  Growth Factors

For patients with metastatic colorectal cancer (mCRC), epidermal growth factor receptor (EGFR) inhibitors are limited to patients ..

Phase III Trial of Avelumab Maintenance After First-Line Induction Chemotherapy Versus Continuation of Chemotherapy in Patients With Gastric Cancers: Results From JAVELIN Gastric 100.

Markus Moehler, Mikhail Dvorkin, Narikazu Boku, Mustafa Özgüroğlu, Min-Hee Ryu, Alina S Muntean, Sara Lonardi, Marina Nechaeva, Arinilda C Bragagnoli, Hasan S Coşkun, Antonio Cubillo Gracian, Toshimi Takano, Rachel Wong, Howard Safran, Gina M Vaccaro, Zev A Wainberg, Matthew R Silver, Huiling Xiong, Janet Hong, Julien Taieb, et al.

Journal article  |  2021  |  Journal of Clinical Oncology

PURPOSE: The role of maintenance therapy for gastric (GC) or gastroesophageal junction cancer (GEJC) is unclear. We investigated a..

Cancer Clinical Trial Versus Real-World Outcomes for Standard of Care First-Line Treatment in the Advanced Disease Setting.

Louise Kostos, Wei Hong, Belinda Lee, Ben Tran, Sheau-Wen Lok, Angelyn Anton, Grace Gard, Yat Hang To, Vanessa Wong, Jeremy Shapiro, Rachel Wong, Shirley Wong, Richard De Boer, Peter Gibbs

Journal article  |  2021  |  International Journal of Cancer

Clinical trials have strict eligibility criteria, potentially limiting external validity. However, while often discussed this has ..

Real-World Treatment and Outcomes of Metastatic Colorectal Cancer Patients With a Poor or Very Poor Performance Status.

Avraham Travers, Azim Jalali, Stephen Begbie, Christine Semira, Suzanne Kosmider, Sumitra Ananda, Rachel Wong, Margaret Lee, Jeremy Shapiro, Matthew Burge, Desmond Yip, Javier Torres, Brigette Ma, Louise Nott, Andrew Dean, Jeanne Tie, Adnan Khattak, Stephanie Lim, Hui-Li Wong, Peter Gibbs

Journal article  |  2021  |  Clinical Colorectal Cancer

BACKGROUND: The management of metastatic colorectal cancer patients with a poor performance status (PS) continues to be a clinical..

BRAFV600E Mutations Arising from a Left-Side Primary in Metastatic Colorectal Cancer: Are They a Distinct Subset?

Vanessa Wong, Margaret Lee, Rachel Wong, Jeanne Tie, Jeremy Shapiro, Jayesh Desai, Louise Nott, Simone Steel, Matthew Burge, Brigette Ma, Adnan Khattak, Wei Hong, Peter Gibbs

Journal article  |  2021  |  Targeted Oncology

BACKGROUND: B-Raf proto-oncogene (BRAF)-V600E mutations (BRAFmt) in colorectal cancer (CRC) predominantly occur in right-side (RS)..

Metastasectomy and BRAF mutation; an analysis of survival outcome in metastatic colorectal cancer.

Thiru Prasanna, Rachel Wong, Timothy Price, Jeremy Shapiro, Jeanne Tie, Hui-Li Wong, Louise Nott, David Roder, Margaret Lee, Suzanne Kosmider, Azim Jalali, Matthew Burge, Robert Padbury, Guy Maddern, Scott Carruthers, James Moore, Michael Sorich, Christos S Karapetis, Peter Gibbs, Desmond Yip

Journal article  |  2021  |  Current Problems in Cancer

BACKGROUND: Resection of oligometastases improves survival in metastatic colorectal cancer (mCRC). It is unclear whether the benef..

Results of phase II trial of intensified neoadjuvant treatment with interdigitating radiotherapy and chemotherapy with oxaliplatin, 5-fluorouracil and folinic acid in patients with locally advanced rectal cancer (PROARCT trial).

Sweet Ping Ng, Julie Chu, Sarat Chander, Mathias Bressel, Joseph McKendrick, Rachel Wong, Malcolm Steel, William K Murray, Trevor Leong, Alexander Heriot, Michael Michael, Samuel Y Ngan

Journal article  |  2021  |  Radiotherapy and Oncology

BACKGROUND AND PURPOSE: The chemotherapy exposure during chemoradiotherapy for rectal cancer is adequate for radiosensitization bu..

Dual Antiangiogenesis Agents Bevacizumab Plus Trebananib, without Chemotherapy, in First-line Treatment of Metastatic Colorectal Cancer: Results of a Phase II Study.

Jennifer Mooi, Fiona Chionh, Peter Savas, Jessica Da Gama Duarte, Geoffrey Chong, Stephen Brown, Rachel Wong, Timothy J Price, Alysson Wann, Effie Skrinos, John M Mariadason, Niall C Tebbutt

Journal article  |  2021  |  Clinical Cancer Research

PURPOSE: To assess the efficacy and safety of dual antiangiogenesis agents, bevacizumab plus trebananib, without chemotherapy, in ..

Characteristics and outcomes of participants in colorectal cancer biomarker trials versus a real-world cohort

Siavash Foroughi, Hui-li Wong, Jeanne Tie, Rachel Wong, Margaret Lee, Belinda Lee, Ian Jones, Iain Skinner, Antony W Burgess, Peter Gibbs

Journal article  |  2020  |  Acta Oncologica

BACKGROUND: The restrictive eligibility criteria of therapy-focused cancer clinical trials can limit the external validity of the ..

Dose modification for haematological toxicity: a survey of Australian medical oncologists.

Wanyuan Cui, Julia Shingleton, Liesel Byrne, Aisling Kelly, Lisa King, Phillipa Smith, Craig R Lewis, Brian N Stein, Jeremy Shapiro, Christos Karapetis, Rachel Wong

Journal article  |  2020  |  Internal Medicine Journal

BACKGROUND: Evidence supporting dose modifications to reduce serious treatment-related adverse events of antineoplastic therapy is..