Peter-Phillip de Cruz

Comparison of the Risk of Crohn's Disease Postoperative Recurrence Between Modified Rutgeerts Score i2a and i2b Categories: An Individual Patient Data Meta-analysis.

Pauline Rivière, Joel Pekow, Nassim Hammoudi, Pauline Wils, Peter De Cruz, Christina Pu Wang, Míriam Mañosa, Jacob Ollech, Matthieu Allez, Maria Nachury, Michael A Kamm, Maya Ahanori, Marc Ferrante, Anthony Buisson, Siddarth Singh, David Laharie, Momar Diouf, Mathurin Fumery

Journal article  |  2023  |  J Crohns Colitis

BACKGROUND: The modified Rutgeerts' score [RS] differentiates i2a-lesions confined to the anastomosis-and i2b-more than five aphth..

Dose intensification strategy influences infliximab pharmacokinetics but not clinical response after the same number of doses

Ashish Srinivasan, Peter De Cruz, Melissa Sam, Catherine Toong, Daniel R van Langenberg

Journal article  |  2023  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

BACKGROUND: The optimal infliximab dose intensification strategy to address secondary loss of response (LOR) remains unclear. This..

Up-front infliximab dose intensification for secondary loss of response in inflammatory bowel disease: Similar efficacy to dose-interval shortening with the added advantage of early clinical and pharmacokinetic predictors of durable response

A Srinivasan, P De Cruz, M Sam, C Toong, D Van Langenberg

Conference Proceedings  |  2022  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Recommendations for Standardizing Clinical Trial Design and Endoscopic Assessment in Postoperative Crohn's Disease.

Jurij Hanzel, Vipul Jairath, Peter De Cruz, Leonardo Guizzetti, Lisa M Shackelton, Peter Bossuyt, Marjolijn Duijvestein, Parambir S Dulai, Johannes Grossmann, Robert P Hirten, Reena Khanna, Julian Panes, Laurent Peyrin-Biroulet, Miguel Regueiro, David T Rubin, Siddharth Singh, Ryan W Stidham, William J Sandborn, Brian G Feagan, Geert R D'Haens, et al.

Journal article  |  2022  |  Inflamm Bowel Dis

BACKGROUND: The lack of standardized methods for clinical trial design and disease activity assessment has contributed to an absen..

Non-invasive Serological Monitoring for Crohn's Disease Postoperative Recurrence

Amy L Hamilton, Peter De Cruz, Emily K Wright, Thierry Dervieux, Anjali Jain, Michael A Kamm

Journal article  |  2022  |  JOURNAL OF CROHNS & COLITIS

INTRODUCTION: Crohn's disease recurs after intestinal resection. This study evaluated accuracy of a new blood test, the Endoscopic..

Higher Anti-tumor Necrosis Factor-alpha Levels Correlate With Improved Radiologic Outcomes in Crohn's Perianal Fistulas

Michael De Gregorio, Tanya Lee, Krupa Krishnaprasad, Gregory Amos, Yoon-Kyo An, Matthew Bastian-Jordan, Jakob Begun, Nira Borok, Dougal JM Brown, Wa Cheung, Susan J Connor, Jan Gerstenmaier, Lauren E Gilbert, Robert Gilmore, Bonita Gu, Numan Kutaiba, Allan Lee, Gillian Mahy, Ashish Srinivasan, Lena Thin, et al.

Journal article  |  2022  |  CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

BACKGROUND & AIMS: Higher anti-tumor necrosis factor-α (TNF) drug levels are associated with improved clinical healing of Crohn's ..

Mo1541: INFLIXIMAB DOSE INTENSIFICATION FOR SECONDARY LOSS OF RESPONSE IN IBD: UPFRONT INTENSIFICATION IS SIMILARLY EFFECTIVE TO DOSE INTERVAL SHORTENING WITH THE ADDED BENEFIT OF EARLY PREDICTORS OF RESPONSE

Ashish Srinivasan, Peter De Cruz, Melissa Sam, Catherine Toong, Daniel R Van Langenberg

Journal article  |  2022  |  Gastroenterology

EP1292: MONOCYTE DISTRIBUTION WIDTH IS ASSOCIATED WITH INFLIXIMAB RESPONSE IN ACUTE SEVERE ULCERATIVE COLITIS

Christopher Li Wai Suen, Matthew Choy, Joanne Wiid, Kristy Boyd, Raquel Pena, Kathryn Burrell, Kumar Visvanathan, Peter De Cruz

Journal article  |  2022  |  Gastroenterology

Tu1497: COMPARISON OF THE RISK OF CLINICAL RECURRENCE AFTER ILEOCOLONIC RESECTION FOR CROHN'S DISEASE FOR MODIFIED RUTGEERTS’ SCORE I2A AND I2B CATEGORIES: INDIVIDUAL PATIENT DATA META-ANALYSIS.

Pauline Rivière, Joel Pekow, Nassim Hammoudi, Pauline Wils, Peter De Cruz, Christina P Wang, Miriam Mañosa, Jacob Ollech, Matthieu Allez, Maria Nachury, Michael A Kamm, Maya Aharoni Golan, Marc Ferrante, Anthony Buisson, Siddharth Singh, David Laharie, Diouf Momar, Mathurin Fumery

Journal article  |  2022  |  Gastroenterology

EP1308: 6-THIOGUANINE NUCLEOTIDE LEVELS AND ANTI-TNFα TROUGH LEVELS IN INFLAMMATORY BOWEL DISEASE PATIENTS ON COMBINATION THERAPY: A RETROSPECTIVE MULTICENTRE STUDY

Natalie Yu, Daniel Tassone, Tanya Lee, Steven Phan, Damien M Wu, Jason Zhang, Luke Wang, Jason Tjahyadi, Krishneel Dutt, Hana Liou, Chamara Basnayake, Emily K Wright, Mark Lust, Ola Niewiadomski, Michael A Kamm, William Connell, Alexander Thompson, Ida Hilmi, Raja Affendi Raja Ali, Shu Chen Wei, et al.

Journal article  |  2022  |  Gastroenterology