Sarath Ranganathan

Effectiveness of Intranasal Mometasone Furoate vs Saline for Sleep-Disordered Breathing in Children A Randomized Clinical Trial

Alice Baker, Anneke Grobler, Karen Davies, Amanda Griffiths, Harriet Hiscock, Haytham Kubba, Rachel L Peters, Sarath Ranganathan, Joanne Rimmer, Elizabeth Rose, Katherine Rowe, Catherine M Simpson, Andrew Davidson, Gillian Nixon, Kirsten P Perrett

Journal article  |  2023  |  JAMA PEDIATRICS

IMPORTANCE: Obstructive sleep-disordered breathing (SDB) in children is characterized by snoring and difficulty breathing during s..

Association between early respiratory viral infections and structural lung disease in infants with cystic fibrosis.

Don B Sanders, Ashley R Deschamp, Joseph E Hatch, James E Slaven, Netsanet Gebregziabher, Mariette Kemner-van de Corput, Harm AWM Tiddens, Tim Rosenow, Gregory A Storch, Graham L Hall, Stephen M Stick, Sarath Ranganathan, Thomas W Ferkol, Stephanie D Davis

Journal article  |  2022  |  J Cyst Fibros

BACKGROUND: Infants with cystic fibrosis (CF) develop structural lung disease early in life, and viral infections are associated w..

Macrophage PD-1 associates with neutrophilia and reduced bacterial killing in early cystic fibrosis airway disease.

Camilla Margaroli, Hamed Horati, Luke W Garratt, Vincent D Giacalone, Craig Schofield, A Susanne Dittrich, Tim Rosenow, Brian S Dobosh, Hong S Lim, Dario L Frey, Mieke Veltman, George L Silva, Milton R Brown, Carsten Schultz, Harm AWM Tiddens, Sarath Ranganathan, Joshua D Chandler, Peng Qiu, Limin Peng, Bob J Scholte, et al.

Journal article  |  2022  |  J Cyst Fibros

BACKGROUND: Macrophages are the major resident immune cells in human airways coordinating responses to infection and injury. In cy..

386 Association between myeloperoxidase activity and methionine oxidation products in bronchoalveolar lavage and risk of bronchiectasis in infants and toddlers with cystic fibrosis

S Kim, G Collins, D Moncada Giraldo, V Giacalone, S Shanthikumar, P Rao, S Ranganathan, S Stick, R Tirouvanziam, J Chandler

Journal article  |  2022  |  Journal of Cystic Fibrosis

414 Longitudinal analysis of early-life bronchoalveolar fluid identifies immune mediators associated with bronchiectasis risk in children with cystic fibrosis

D Moncada Giraldo, V Giacalone, S Shanthikumar, S Ranganathan, P Rao, S Stick, J Chandler, C Esther, R Tirouvanziam

Journal article  |  2022  |  Journal of Cystic Fibrosis

446 Metabolites in early life bronchoalveolar fluid associate with future bronchiectasis risk in children with cystic fibrosis

S Shanthikumar, S Kim, V Giacalone, P Rao, S Ranganathan, Y Karpievitch, S Stick, R Boucher, R Tirouvanziam, J Chandler, C Esther

Journal article  |  2022  |  Journal of Cystic Fibrosis

Long-term expiratory airflow of infants born moderate-late preterm: A systematic review and meta-analysis.

Cassidy Du Berry, Christopher Nesci, Jeanie LY Cheong, Tara FitzGerald, Rheanna Mainzer, Sarath Ranganathan, Lex W Doyle, Elianne JLE Vrijlandt, Liam Welsh

Journal article  |  2022  |  EClinicalMedicine

BACKGROUND: Moderate-late preterm (MLP; 32 to <37 weeks' gestation) birth is associated with reduced expiratory airflow during chi..

Maternal gut microbiota during pregnancy and the composition of immune cells in infancy

Yuan Gao, Martin O'Hely, Thomas P Quinn, Anne-Louise Ponsonby, Leonard C Harrison, Hanne Frokiaer, Mimi LK Tang, Susanne Brix, Karsten Kristiansen, Dave Burgner, Richard Saffery, Sarath Ranganathan, Fiona Collier, Peter Vuillermin

Journal article  |  2022  |  FRONTIERS IN IMMUNOLOGY

BACKGROUND: Preclinical studies have shown that maternal gut microbiota during pregnancy play a key role in prenatal immune develo..

Long term pulmonary function of infants born moderate-late preterm – A systematic review and meta-analysis

C Du Berry, C Nesci, J Cheong, T Fitzgerald, S Ranganathan, R Mainzer, L Doyle, E Vrijlandt, L Welsh

Conference Proceedings  |  2022  |  09.01 - Respiratory function technologists/scientists

A multimodal cell atlas of the pediatric lower airway

S Shanthikumar, J Maksimovic, A Oshlack, S Ranganathan, M Neeland

Conference Proceedings  |  2022  |  07.03 - Paediatric cystic fibrosis (CF)