Sarath Ranganathan

Optimism with Caution: Elexacaftor-Tezacaftor-Ivacaftor in Patients with Advanced Pulmonary Disease.

Stephanie L Kuek, Sarath C Ranganathan, Joanne Harrison, Philip J Robinson, Shivanthan Shanthikumar

Journal article  |  2021  |  American Journal of Respiratory and Critical Care Medicine

Infant pacifier sanitization and risk of challenge- proven food allergy: A cohort study

Victoria X Soriano, Jennifer J Koplin, Mike Forrester, Rachel L Peters, Martin O'Hely, Shyamali C Dharmage, Rosemary Wright, Sarath Ranganathan, David Burgner, Kristie Thompson, Terence Dwyer, Peter Vuillerman, Anne-Louise Ponsonby

Journal article  |  2021  |  Journal of Allergy and Clinical Immunology

BACKGROUND: Environmental microbial exposure plays a role in immune system development and susceptibility to food allergy. OBJECTI..

Assessing the impact of the 13 valent pneumococcal vaccine on childhood empyema in Australia

Roxanne Strachan, Nusrat Homaira, Sean Beggs, Mejbah U Bhuiyan, Gwendolyn L Gilbert, Stephen B Lambert, Kristine Macartney, Helen Marshall, Andrew C Martin, Gabrielle B McCallum, Angela McCullagh, Tim McDonald, Peter McIntyre, Shahin Oftadeh, Sarath Ranganathan, Sadasivam Suresh, Claire E Wainwright, Angela Wilson, Melanie Wong, Thomas Snelling, et al.

Journal article  |  2021  |  Thorax

BACKGROUND: Empyema is a serious complication of pneumonia frequently caused by Streptococcus pneumoniae (SP). We assessed the imp..

A bacterial stimulation assay for bronchoalveolar lavage immune cells from young children with cystic fibrosis

Haipei Liu, Sohinee Sarkar, Kristy Azzopardi, Sophie Day, Serene Yeow, Sarath Ranganathan, Philip Sutton

Journal article  |  2021  |  Scandinavian Journal of Immunology

Cystic Fibrosis (CF) is primarily a progressive lung disease, characterized by chronic pulmonary infections with opportunistic pat..

The clinical features that contribute to poor bone health in young Australians living with cystic fibrosis: A recommendation for BMD screening

Gabby Atlas, Matthew Yap, Angelina Lim, Suzanna Vidmar, Nathan Smith, Louise King, Alicia Jones, Jason Hong, Sarath Ranganathan, Peter J Simm

Journal article  |  2021  |  Pediatric Pulmonology

BACKGROUND: For Australians living with cystic fibrosis (CF), increased longevity means greater consideration needs to be given to..

Maternal and Cord Blood 25-Hydroxyvitamin D-3 Are Associated with Increased Cord Blood and Naive and Activated Regulatory T Cells: The Barwon Infant Study

Steffen U Thorsen, Fiona Collier, Angela Pezic, Martin O'Hely, Michael Clarke, Mimi LK Tang, David Burgner, Peter Vuillermin, Anne-Louise Ponsonby

Journal article  |  2021  |  The Journal of Immunology

Vitamin D has shown immune-modulatory effects but mostly in in vitro and animal studies. Regulatory T cells (Treg) are important f..

Sleep and cardiometabolic health in children and adults: examining sleep as a component of the 24-h day

Lisa Matricciani, Dorothea Dumuid, Catherine Paquet, Francois Fraysse, Yichao Wang, Louise A Baur, Markus Juonala, Sarath Ranganathan, Kate Lycett, Jessica A Kerr, David Burgner, Melissa Wake, Tim Olds

Journal article  |  2021  |  Sleep Medicine

STUDY OBJECTIVES: Sleep, physical activity and sedentary time are all known to play a role in cardiometabolic health. Compositiona..

Sleep and cardiometabolic risk: a cluster analysis of actigraphy-derived sleep profiles in adults and children.

Lisa Matricciani, Catherine Paquet, François Fraysse, Anneke Grobler, Yichao Wang, Louise Baur, Markus Juonala, Minh Thien Nguyen, Sarath Ranganathan, David Burgner, Melissa Wake, Tim Olds

Journal article  |  2021  |  Sleep

STUDY OBJECTIVES: Sleep plays an important role in cardiometabolic health. While the importance of considering sleep as a multidim..

Patient and family perspectives regarding the use of telehealth for cystic fibrosis care

Shivanthan Shanthikumar, Emily Moore, Jen Corda, Nicola Reardon, Stef Louey, Katherine Frayman, Jo Harrison, Sarath Ranganathan

Journal article  |  2021  |  Pediatric Pulmonology

The traditional model of cystic fibrosis (CF) care revolves around regular (usually three monthly) in person appointments with the..

Changes in airway inflammation with pseudomonas eradication in early cystic fibrosis.

Luke W Garratt, Oded Breuer, Craig J Schofield, Samantha A McLean, Daniel R Laucirica, Rabindra Tirouvanziam, Barry S Clements, Anthony Kicic, Sarath Ranganathan, Stephen M Stick, On Behalf Of Arest Cf

Journal article  |  2021  |  Journal of Cystic Fibrosis

BACKGROUND: Neutrophil elastase is a significant risk factor for structural lung disease in cystic fibrosis, and Pseudomonas aerug..