Kulmira Nurgali

Divergent Adaptations in Autonomic Nerve Activity and Neuroimmune Signaling Associated With the Severity of Inflammation in Chronic Colitis

Rhian Stavely, Ahmed A Rahman, Lauren Sahakian, Monica D Prakash, Ainsley M Robinson, Majid Hassanzadeganroudsari, Rhiannon T Filippone, Sarah Fraser, Rajaraman Eri, Joel C Bornstein, Vasso Apostolopoulos, Kulmira Nurgali

Journal article  |  2022  |  INFLAMMATORY BOWEL DISEASES

BACKGROUND: The autonomic nervous system (ANS) is thought to play a critical role in the anti-inflammatory reflex pathway in acute..

Neuroinflammation as an etiological trigger for depression comorbid with inflammatory bowel disease

Colin F Craig, Rhiannon T Filippone, Rhian Stavely, Joel C Bornstein, Vasso Apostolopoulos, Kulmira Nurgali

Journal article  |  2022  |  JOURNAL OF NEUROINFLAMMATION

Patients with inflammatory bowel disease (IBD) suffer from depression at higher rates than the general population. An etiological ..

Characterization of Skeletal Phenotype and Associated Mechanisms With Chronic Intestinal Inflammation in the Winnie Mouse Model of Spontaneous Chronic Colitis

Ahmed Al Saedi, Shilpa Sharma, Ebrahim Bani Hassan, Lulu Chen, Ali Ghasem-Zadeh, Majid Hassanzadeganroudsari, Jonathan H Gooi, Rhian Stavely, Rajaraman Eri, Dengshun Miao, Kulmira Nurgali, Gustavo Duque

Journal article  |  2021  |  INFLAMMATORY BOWEL DISEASES

BACKGROUND: Osteoporosis is a common extraintestinal manifestation of inflammatory bowel disease (IBD). However, studies have been..

Development and validation of a new method to isolate, expand, and differentiate circulating osteogenic precursor (COP) cells

Jack Feehan, Kulmira Nurgali, Vasso Apostolopoulos, Gustavo Duque

Journal article  |  2021  |  BONE REPORTS

Circulating osteogenic precursor (COP) cells are a population of progenitor cells in the peripheral blood with the capacity to for..

Anti-cancer effects of polyphenol-rich sugarcane extract

Monica D Prakash, Lily Stojanovska, Jack Feehan, Kulmira Nurgali, Elizabeth L Donald, Magdalena Plebanski, Matthew Flavel, Barry Kitchen, Vasso Apostolopoulos

Journal article  |  2021  |  PLOS ONE

Plant polyphenols have an array of health benefits primarily thought to be related to their high content of anti-oxidants. These a..

Inhibition of APE1/Ref-1 Redox Signaling Alleviates Intestinal Dysfunction and Damage to Myenteric Neurons in a Mouse Model of Spontaneous Chronic Colitis

Lauren Sahakian, Rhiannon T Filippone, Rhian Stavely, Ainsley M Robinson, Xu Sean Yan, Raquel Abalo, Rajaraman Eri, Joel C Bornstein, Mark R Kelley, Kulmira Nurgali

Journal article  |  2021  |  INFLAMMATORY BOWEL DISEASES

BACKGROUND: Inflammatory bowel disease (IBD) associates with damage to the enteric nervous system (ENS), leading to gastrointestin..

Krill oil extract inhibits the migration of human colorectal cancer cells and down-regulates EGFR signalling and PD-L1 expression

Abilasha G Jayathilake, Margaret F Veale, Rodney Brain Luwor, Kulmira Nurgali, Xiao Q Su

Journal article  |  2020  |  BMC COMPLEMENTARY MEDICINE AND THERAPIES

BACKGROUND: The currently available treatments for colorectal cancer (CRC) are often associated with serious side-effects. Therefo..

Targeted nano-drug delivery system for glioblastoma therapy: In vitro and in vivo study

Majid Hassanzadeganroudsari, Majid Soltani, Amir Heydarinasab, Vasso Apostolopoulos, Azim Akbarzadehkhiyavi, Kulmira Nurgali

Journal article  |  2020  |  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

The Changing Partners of FOXO1 Under High Serotonin Levels in Winnie Mouse Model of Spontaneous Chronic Colitis

Shilpa Sharma, Ahmed Al Saedi, Kulmira Nurgali, Gustavo Duque

Conference Proceedings  |  2020  |  JOURNAL OF BONE AND MINERAL RESEARCH

Assessment of bone microarchitecture and mineralization changes in an animal model of inflammatory bowel disease using high-resolution synchrotron-based microCT

Damian Myers, Christopher Hall, Ahmed Al Saidi, Ali Ghasem Zadeh, Shilpa Sharma, Sara Vogrin, Rhiannon Filippone, Anton Maksimenko, Daniel Hausermann, Kulmira Nurgali, Gustavo Duque

Conference Proceedings  |  2020  |  JOURNAL OF BONE AND MINERAL RESEARCH