Dr Chüeh is a Senior Research Officer in the Personalised Oncology Division at The Walter and Eliza Hall Institute of Medical Research (WEHI). His research employs advance technologies and genetically modified or cancer cell line models to a) study key molecular mechanisms in mitotic signaling, b) investigate the mode of actions of epigenetic enzyme-targeting small molecules, c) discover novel cancer biomarkers predictive of therapeutic response, and d) develop innovative therapeutics in blocking cancer progression.
Dr Chüeh completed his B.BiomedSc Honours in 2003 and obtained his Ph.D. in Human Genetics from The University of Melbourne in 2008 under the supervision of Prof Kong-Hong Andy Choo. He independently constructed and developed an in-house 2-colour genomic tiling PCR-fragment microarray for comparative genomic hybridization (CGH) and chromatin immunoprecipitation (ChIP) applications, in which the technology was successfully transferred to Victorian Clinical Genetics Services for routine molecular diagnosis of chromosomal aberrations in human patients. For his contributions to human genetics as an early career graduate researcher, he was awarded the Honours Soiree Prize from the Human Genetics Society of Australasia. From 2008 until 2013, he completed postdoctoral training at Ludwig Institute of Cancer Research (LICR) under the mentorship of Prof John M. Mariadason, during which time he identified a novel clinically-relevant transcriptional axis that is predictive of HDAC inhibitor drug sensitivity in tumour cells from multiple cancer types. Dr Chüeh was recruited to The Walter and Eliza Hall Institute in 2014 where led target identification and MoA studies on first-in-class small molecule antimitotics that has demonstrated in vivo activities and licensed to commercial partners for co-development. Since 2016, Dr Chüeh has worked as a Senior Scientist contributing to high throughput screening, biomarker identification and target validation to multiple drug discovery pipelines in a leading Australian biotech company (Cancer Therapeutics CRC) that has successfully licensed novel small molecules to multinational pharmaceutical companies such as Merck and Pfizer. Dr Chüeh is also an Associate Editor for UK Biochemical Society’s Biosciences Reports journal and has reviewed more than 40 project and development grants for NHMRC and ARC.
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Anderly Chueh's highlights
FEATURED Journal article
DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis
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Scholarly Works
Displaying the 27 most recent scholarly works by Anderly Chueh.
Honours, Awards and Fellowships
Austin Life Science Research Prize, Finalist (Joint Award)
Ludwig Institute Scholarship (Joint Award)
Austin Medical Research Foundation Young Investigator Award, Finalist (Joint Award)
Overseas Young Health Professionals Travel Award
State Awards for Company of the Year, Best Community and Environment, Winner (Team Award)
National Award for Australia Most Innovative Product or Service, Winner (Team Award)
Leadership Training Course Attendance Scholarship
State Award for ‘Company of the Year’ and ‘Best Media Promotion and Marketing Award’, Honorable Mentions (Team Award)
Dean's Honours Award, Faculty of Medicine (Paediatrics)
Australian Postgraduate Award
PhD Top-Up Scholarship
Honours Soiree Prize
UROP Scholarship
Summer Vacation Scholarship
Year 12 Academic Honours (Dux) - Joint Award
Credentials
Positions
Honorary
Medicine - Austin Health
Honorary
Medical Biology (W.E.H.I.)
Member, Human Genetics Society Of Australasia
Human Genetics Society of Australasia
Member, Taiwan Genomics And Genetics Society
Taiwan Genomics and Genetics Society
Associate Member, American Society Of Clinical Oncology
American Society of Clinical Oncology (ASCO)
Associate Member, American Society Of Clinical Oncology
American Association for Cancer Research (AACR)
Member, American Society Of Human Genetics (Ashg)
American Society of Human Genetics (ASHG)
Education
Doctor of Philosophy in Human Genetics
University of Melbourne
Bachelor of Biomedical Science (Honours)
University of Melbourne
Bachelor of Biomedical Science, Biochemistry and Molecular Biology
University of Melbourne