After completing my PhD at the University of Melbourne (2007), I did my post-doctoral training at the Institute of Molecular and Cell Biology Institute, Singapore with an Australian Endeavour Research Fellowship. I pursued a short stint at the Burnet Institute in 2009, before returning to the University of Melbourne in 2010.
I led a small research team to conduct a commercial contract research towards identifying a GM-CSF gene signature under the auspices of as MorphoSys AG, conducting Phase I anti-GM-CSF clinical trial in rheumatoid arthritis. Following the successful completion of the trial, GlaxoSmithKline acquired the rights to conduct Phase IIb clinical trials. Subsequently, I was instrumental in securing a four-year commercial research contract with GlaxoSmithKline to investigate the molecular mechanisms responsible for GM-CSF-mediated inflammation in rheumatoid arthritis. A number of publications in leading journals and a significant patent emerged from this. In 2018, I was appointed as the Honours Coordinator at the Department of Medicine, Royal Melbourne Hospital overseeing the largest cohort of Honour students in the Faculty of Medicine, Dentistry and Health Sciences at the University of Melbourne.
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Adrian Achuthan's highlights
FEATURED Journal article
Targeting GM-CSF for collagenase-induced osteoarthritis pain and disease in mice
Read moreAdrian Achuthan's selected work
Cytokines in inflammation
Research Contracts
Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macro..
Journal article
REBALANCING THE LEVELS OF CCL17 AND CCL22 TO IMPROVE RHEUMATOID ARTHRITIS
Research Grant
GM-CSF- and IRF4-Dependent Signaling Can Regulate Myeloid Cell Numbers and the Macrophage ..
Journal article
CCL17 IS A GENERAL PAIN REGULATOR - LEX 31020
Research Contracts
CSF-1 in Inflammatory and Arthritic Pain Development
Journal article
Adrian Achuthan's selected work
Projects
Displaying the 5 most recent projects by Adrian Achuthan.
Project Types
3
Research Contracts
1
Internal Research Grant
1
Research Grant
Additional Information
2017 Milstein Travel Award by International Cytokine and Interferon Society, Cytokines 2017 Conference in Kanazawa, Japan 2017 Travel Grant by Society for Cytokines, Inflammation and Leukocytes, 13th World congress on Inflammation, London, UK 2016 Travel Award by ELSEVIER, 100 Years of Phagocytes Conference, Sicily, Italy 2014 Travel Grant by CASS Foundation, FEBS-EMBO 2014 Conference, Paris, France 2010 ASBMB Fellowship, Experimental Biology 2010 Conference, Anaheim, CA 2009 Travel Award by American Society for Biochemistry and Molecular Biology, Annual Scientific Meeting, Anaheim, CA 2008 Endeavour Research Fellowship, Institute for Molecular and Cell Biology, Singapore
Scholarly Works
Displaying the 10 most recent scholarly works by Adrian Achuthan.
Keyword Analysis
Honours, Awards and Fellowships
Postgraduate
Undergraduate
Credentials
Positions
Positions
Senior Research Fellow
Medicine - Royal Melbourne Hospital
Member
Australasian Society for Immunology
Member
International Cytokine & Interferon Society
Member
American Society for Biochemistry and Molecular Biology
Member
International Society for Fibrinolysis and Proteolysis
Member
Australian Society for Biochemistry and Molecular Biology
Education
Education
Bachelor of Biomedical Science (Hons)
University of Melbourne
PhD
University of Melbourne
Master of Applied Finance
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