David Gardner

A microenvironment of high lactate and low pH created by the blastocyst promotes endometrial receptivity and implantation

Kathryn H Gurner, Jemma Evans, Jennifer C Hutchison, Alexandra J Harvey, David K Gardner

Journal article  |  2021  |  Reproductive BioMedicine Online

O-026 Advanced Glycation Endproducts: A new player in obesity related infertility

J Hutchison, TT Truong, TA Egell, LA Salamonsen, DK Gardner, J Evans

Journal article  |  2021  |  Human Reproduction

Abstract text Globally, 39% of the adult population is overweight or obese, with the prevalence of obesity followin..

In vitro fertilization and andrology laboratories in 2030.

Carlos Simon, Alison Campbell, David K Gardner, Marcos Meseguer, Kathleen A Miller, Markus Montag, Gianpiero D Palermo, Stephanie Cheung, Derek Keating, Philip Xie, Zev Rosenwaks, Laura Rienzi, Federica Innocenti, Danilo Cimadomo, Filippo Maria Ubaldi, Denny Sakkas, Michael J Tucker, Liesl Nel-Themaat

Journal article  |  2021  |  Fertility and Sterility

The in vitro fertilization and andrology laboratories are at the center of assisted reproductive technologies and the place where ..

In vitro fertilization and andrology laboratory in 2030: expert visions.

Alison Campbell, David K Gardner, Marcos Meseguer, Kathleen A Miller, Markus Montag, Gianpiero D Palermo, Stephanie Cheung, Derek Keating, Philip Xie, Zev Rosenwaks, Laura Rienzi, Federica Innocenti, Danilo Cimadomo, Filippo Maria Ubaldi, Denny Sakkas, Michael J Tucker, Liesl Nel-Themaat, Carlos Simon

Journal article  |  2021  |  Fertility and Sterility

The aim of this article is to gather 9 thought leaders and their team members to present their ideas about the future of in vitro ..

A pilot study investigating a novel particle-based growth factor delivery system for preimplantation embryo culture.

Kathryn H Gurner, Joseph J Richardson, Alexandra J Harvey, David K Gardner

Journal article  |  2021  |  Hum Reprod

STUDY QUESTION: Can vascular endothelial growth factor (VEGF)-loaded silica supraparticles (V-SPs) be used as a novel mode of deli..

A combination of growth factors and cytokines alter preimplantation mouse embryo development, foetal development and gene expression profiles

Kathryn H Gurner, Thi T Truong, Alexandra J Harvey, David K Gardner

Journal article  |  2020  |  Molecular Human Reproduction

Within the maternal tract, the preimplantation embryo is exposed to an array of growth factors (GFs) and cytokines, most of which ..

Advanced glycation end products present in the obese uterine environment compromise preimplantation embryo development

Jennifer C Hutchison, Thi T Truong, Lois A Salamonsen, David K Gardner, Jemma Evans

Journal article  |  2020  |  REPRODUCTIVE BIOMEDICINE ONLINE

Research question Proinflammatory advanced glycation end products (AGE), highly elevated within the uterine cavity of obese women,..

Comparing pregnancy outcomes between natural cycles and artificial cycles following frozen-thaw embryo transfers

Cassandra Pakes, Michelle Volovsky, Genia Rozen, Franca Agresta, David K Gardner, Alex Polyakov

Journal article  |  2020  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

Background Frozen embryo transfer (FET) is increasing in prevalence. In contrast to the amount of research performed on the actual..

Metabolic activity of human blastocysts correlates with their morphokinetics, morphological grade, KIDScore and artificial intelligence ranking

Laura Ferrick, Yee Shan Lisa Lee, David K Gardner

Journal article  |  2020  |  HUMAN REPRODUCTION

STUDY QUESTION Is there a relationship between blastocyst metabolism and biomarkers of embryo viability? SUMMARY ANSWER Blastocys..

In memory of Michelle Lane: 1970 - 2020.

David Gardner, Deirdre Zander-Fox, Hassan W Bakos, Nicole McPherson, Leanne Pacella-Ince

Journal article  |  2020  |  Reprod Biomed Online