profile icon
Prof

David Gardner

Professor
Biosciences
oocyte
embryology
IVF
sperm
mammalian embryology
human assisted conception
science & technology
life sciences & biomedicine
reproductive biology
David Gardner's Profile Picture
Prof

David Gardner

 
Division
Science
 
Primary Interest
Reproductive Biology
David Gardner's Profile Picture
Prof

David Gardner

 
Print
David's  Short Profile
 

Projects

Displaying the 10 most recent projects by David Gardner.

Project icon

DEFINING THE EPIGENETIC ORIGINS OF MATERNALLY INHERITED DISEASE.

Epigenetic (non genetic) changes to the DNA in sperm and eggs can alter outcomes in children. Despite the potential for drugs and diet to me..

2018 - 2020
Completed
Project icon

DETERMINING THE IMPACTS OF EPIGENETIC MODIFYING DRUGS ON GERMLINE PROGRAMMING AND OFFSPRING HEALTH

New drugs have been developed that inhibit specific enzymes that regulate epigenetic pathways in cells. These pathways significantly affect ..

2018 - 2020
Completed
Project icon

Development of an E8-based culture medium for pluripotent stem cell culture

2017 - 2018
Completed
Project icon

CONFOCAL MICROSCOPE WITH LIVE IMAGING CHAMBER

2016 - 2017
Completed
Project icon

EMBRYO CULTURE AND ANALYSIS OF VIABILITY

2014 - 2023
Active
Project icon

ANALYSIS OF EMBRYO VIABILITY (SIMPLE MICROFLUIDIC DEVICE FOR ANALYSING CELL CULTURE MEDIA SAMPLES)

2013 - 2013
Completed
Project icon

Intergenerational transmission of gender-specific metabolic disease for offspring born small: maternal, paternal and embryonic roles

This proposal addresses the underlying metabolic health consequences of poor embryo and growth of the baby across generations. We will defin..

2013 - 2015
Completed
Project icon

Intergenerational transmission of gender-specific metabolic disease for offspring born small: maternal, paternal and embryonic roles

This proposal addresses the underlying metabolic health consequences of poor embryo and growth of the baby across generations. We will defin..

2013 - 2015
Completed
Project icon

ANALYSIS OF EMBRYO VIABILITY (SIMPLE MICROFLUIDIC DEVICE FOR ANALYSING CELL CULTURE MEDIA SAMPLES)

2012 - 2013
Completed
Project icon

Intergenerational transmission of metabolic disease for offspring born small: maternal, paternal and embryonic roles

2012 - 2013
Completed

27

Projects

Project Types

16

Research Grant

9

Research Contracts

2

Internal Research Grant

Scholarly Works

Displaying the 10 most recent scholarly works by David Gardner.

Scholarly works icon

A combination of growth factors and cytokines alter preimplantation mouse embryo development, foetal development and gene expression profiles.

Kathryn H Gurner, Thi T Truong, Alexandra J Harvey, David K Gardner

Journal article  |  2020  |  Molecular Human Reproduction

Within the maternal tract, the preimplantation embryo is exposed to an array of growth factors (GFs) and cytokines, most of which ..

Scholarly works icon

Advanced glycation end products present in the obese uterine environment compromise preimplantation embryo development

Jennifer C Hutchison, Thi T Truong, Lois A Salamonsen, David K Gardner, Jemma Evans

Journal article  |  2020  |  Reproductive BioMedicine Online

RESEARCH QUESTION: Proinflammatory advanced glycation end products (AGE), highly elevated within the uterine cavity of obese women..

Scholarly works icon

Metabolic activity of human blastocysts correlates with their morphokinetics, morphological grade, KIDScore and artificial intelligence ranking

Laura Ferrick, Yee Shan Lisa Lee, David K Gardner

Journal article  |  2020  |  Human Reproduction

STUDY QUESTION: Is there a relationship between blastocyst metabolism and biomarkers of embryo viability? SUMMARY ANSWER: Blastocy..

Scholarly works icon

In memory of Michelle Lane: 1970 - 2020.

David Gardner, Deirdre Zander-Fox, Hassan W Bakos, Nicole McPherson, Leanne Pacella-Ince

Journal article  |  2020  |  Reproductive BioMedicine Online

Scholarly works icon

In memory of Michelle Lane: 1970-2020 OBITUARY

David Gardner, Deirdre Zander-Fox, Hassan W Bakos, Nicole McPherson, Leanne Pacella-Ince

Journal article  |  2020  |  Reproductive biomedicine online

Scholarly works icon

Nicotinamide adenine dinucleotide induces a bivalent metabolism and maintains pluripotency in human embryonic stem cells

Jarmon G Lees, David K Gardner, Alexandra J Harvey

Journal article  |  2020  |  Stem Cells

Nicotinamide adenine dinucleotide (NAD+ ) and its precursor metabolites are emerging as important regulators of both cell metaboli..

Scholarly works icon

Prospective randomized multicentre comparison on sibling oocytes comparing G-Series media system with antioxidants versus standard G-Series media system

David K Gardner, Takeshi Kuramoto, Miho Tanaka, Shigetoshi Mitzumoto, Markus Montag, Atsumi Yoshida

Journal article  |  2020  |  Reproductive BioMedicine Online

RESEARCH QUESTION: Does the inclusion of three antioxidants (A3), acetyl-l-carnitine (ALC), N-acetyl-l-cysteine (NAC) and alpha-li..

Scholarly works icon

The IVF Cycle to Come: Laboratory Innovations

Denny Sakkas, David K Gardner

Book Chapter  |  2020

Scholarly works icon

Antioxidants increase blastocyst cryosurvival and viability post-vitrification

Thi T Truong, David K Gardner

Journal article  |  2020  |  Human Reproduction

STUDY QUESTION: What is the effect of antioxidants acetyl-L-carnitine, N-acetyl-L-cysteine and α-lipoic acid (A3) in vitrification..

Scholarly works icon

Uterine microbiome-low biomass and high expectations†.

Iolanda Garcia-Grau, Carlos Simon, Inmaculada Moreno

Journal article  |  2019  |  Biology of Reproduction

The existence of different bacterial communities throughout the female reproductive tract has challenged the traditional view of h..

390

Scholarly Works

Keyword Analysis

Clinical Sciences
Paediatrics and Reproductive Medicine
Clinical (organs, Diseases and Abnormal Conditions)
Expanding Knowledge
Clinical Health (organs, Diseases and Abnormal Conditions)
Biochemistry and Cell Biology
Zoology
Animal Production
Genetics
Medical Biochemistry and Metabolomics

Honours, Awards and Fellowships

2006

Earl Plunkett Lecturer

University of Western Ontario, Canada
2005

Robert Edwards Scientific Achievement Award

American Fertility Association
2002

Visiting Professor

University of Zhongshan, China
1997

SART Prize Paper

American Society for Reproductive Medicine
1994

Fellowship

ARC
1991

Junior Scientist Award

Australian Society for Reproductive Biology
1986

K. M. Stott Prize for Excellence in Scientific Research

University of York
1985

K. M. Stott Prize for Excellence in Scientific Research

University of York
1984

Science and Engineering Research Council Scholarship

Science and Engineering Research Council
2017

FAA - Fellow of the Australian Academy of Science

10

Awards

Credentials

Positions

Professor

Biosciences

Member

American Society for Reproductive Medicine

Member

European Society for Human Reproduction and Embryology

Member

International Embryo Transfer Society

Education

Doctor of Biology

University of York

Bachelor of Science (Honours)

University of York

Links