Marco Sani

The membrane activity of the antimicrobial peptide caerin 1.1 is pH dependent.

Marc-Antoine Sani, Anton P Le Brun, Sunnia Rajput, Troy Attard, Frances Separovic

Journal article  |  2023  |  Biophys J

Antimicrobial peptides are an important class of membrane-active peptides that can provide alternatives or complements to classic ..

The membrane activity of the antimicrobial peptide caerin 1.1 is pH dependent

MA Sani, APL Brun, S Rajput, T Attard, F Separovic

Journal article  |  2023  |  Biophysical journal

Transient RNA Interactions Leave a Covalent Imprint on a ViralCapsid Protein

Zahra Harati Taji, Pavlo Bielytskyi, Mikhail Shein, Marc-Antoine Sani, Stefan Seitz, Anne K Schutz

Journal article  |  2022  |  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The hepatitis B virus (HBV) is the leading cause of persistent liver infections. Its DNA-based genome is synthesized through rever..

NMR spectroscopy of lipidic cubic phases.

Sunnia Rajput, Shenggen Yao, David W Keizer, Marc-Antoine Sani, Frances Separovic

Journal article  |  2022  |  Biophys Rev

Lipidic cubic phase (LCP) structures have been used for stabilisation and crystallisation of membrane proteins and show promising ..

Enhancing proline-rich antimicrobial peptide action by homodimerization: influence of bifunctional linker

Wenyi Li, Feng Lin, Andrew Hung, Anders Barlow, Marc-Antoine Sani, Rita Paolini, William Singleton, James Holden, Mohammed Akhter Hossain, Frances Separovic, Neil M O'Brien-Simpson, John D Wade

Journal article  |  2022  |  CHEMICAL SCIENCE

Antimicrobial peptides (AMPs) are host defense peptides, and unlike conventional antibiotics, they possess potent broad spectrum a..

Multi-Omic Analysis to Characterize Metabolic Adaptation of the E. coli Lipidome in Response to Environmental Stress

Thomas Kralj, Madison Nuske, Vinzenz Hofferek, Marc-Antoine Sani, Tzong-Hsien Lee, Frances Separovic, Marie-Isabel Aguilar, Gavin E Reid

Journal article  |  2022  |  METABOLITES

As an adaptive survival response to exogenous stress, bacteria undergo dynamic remodelling of their lipid metabolism pathways to a..

Systematic comparison of activity and mechanism of antimicrobial peptides against nosocomial pathogens

Bruce Lin, Andrew Hung, Rong Li, Anders Barlow, William Singleton, Tamara Matthyssen, Marc-Antoine D Sani, Mohammed Akhter Hossain, John Wade, Neil M O'Brien-Simpson, Wenyi Li

Journal article  |  2022  |  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The World Health Organisation has deemed several multi-drug resistant (MDR) nosocomial bacterial pathogens to be of significant th..

In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide

Frances Separovic, Vinzenz Hofferek, Anthony P Duff, Malcom J McConville, Marc-Antoine Sani

Journal article  |  2022  |  JOURNAL OF STRUCTURAL BIOLOGY-X

Dynamic nuclear polarization NMR spectroscopy was used to investigate the effect of the antimicrobial peptide (AMP) maculatin 1.1 ..

The impact of antibacterial peptides on bacterial lipid membranes depends on stage of growth

Tzong-Hsien Lee, Vinzenz Hofferek, Marc-Antoine Sani, Frances Separovic, Gavin E Reid, Marie-Isabel Aguilar

Journal article  |  2021  |  FARADAY DISCUSSIONS

The impact of maculatin 1.1 (Mac1) on the mechanical properties of supported lipid membranes derived from exponential growth phase..

Spectroscopic study of L-DOPA and dopamine binding on novel gold nanoparticles towards more efficient drug-delivery system for Parkinson's disease

Nikolina Kalcec, Nikolina Peranic, Rinea Barbir, Christopher R Hall, Trevor A Smith, Marc Antoine Sani, Ruza Frkanec, Frances Separovic, Ivana Vinkovic Vrcek

Journal article  |  2021  |  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Nano-drug delivery systems may potentially overcome current challenges in the treatment of Parkinson's disease (PD) by enabling ta..