Terence Speed

Serum microRNA is a biomarker for post-operative monitoring in glioma

Andrew Morokoff, Jordan Jones, Hong Nguyen, Chenkai Ma, Arian Lasocki, Frank Gaillard, Iwan Bennett, Rod Luwor, Stanley Stylli, Lucia Paradiso, Rachel Koldej, Iddo Paldor, Ramyar Molania, Terence P Speed, Andrew Webb, Guiseppe Infusini, Jason Li, Charles Malpas, Tomas Kalincik, Katharine Drummond, et al.

Journal article  |  2020  |  Journal of Neuro-Oncology

PURPOSE: A circulating biomarker has potential to provide more accurate information for glioma progression post treatment, however..

DECENT: differential expression with capture efficiency adjustmeNT for single-cell RNA-seq data

Chengzhong Ye, Terence P Speed, Agus Salim

Journal article  |  2019  |  Bioinformatics

MOTIVATION:Dropout is a common phenomenon in single-cell RNA-seq (scRNA-seq) data, and when left unaddressed it affects the validi..

Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network

Sue Haupt, Franco Caramia, Alan Herschtal, Thierry Soussi, Guillermina Lozano, Hu Chen, Han Liang, Terence P Speed, Ygal Haupt

Journal article  |  2019  |  Nature Communications

The disproportionately high prevalence of male cancer is poorly understood. We tested for sex-disparity in the functional integrit..

A new normalization for Nanostring nCounter gene expression data

Ramyar Molania, Johann A Gagnon-Bartsch, Alexander Dobrovic, Terence P Speed

Journal article  |  2019  |  Nucleic Acids Research

The Nanostring nCounter gene expression assay uses molecular barcodes and single molecule imaging to detect and count hundreds of ..

scMerge leverages factor analysis, stable expression, and pseudoreplication to merge multiple single-cell RNA-seq datasets

Yingxin Lin, Shila Ghazanfar, Kevin YX Wang, Johann A Gagnon-Bartsch, Kitty K Lo, Xianbin Su, Ze-Guang Han, John T Ormerod, Terence P Speed, Pengyi Yang, Jean Yee Hwa Yang

Journal article  |  2019  |  Proceedings of the National Academy of Sciences of the United States of America

Using long-read sequencing to detect imprinted DNA methylation

Scott Gigante, Quentin Gouil, Alexis Lucattini, Andrew Keniry, Tamara Beck, Matthew Tinning, Lavinia Gordon, Chris Woodruff, Terence P Speed, Marnie E Blewitt, Matthew E Ritchie

Journal article  |  2019  |  Nucleic Acids Research

Evaluation of cross-platform and interlaboratory concordance via consensus modelling of genomic measurements

Timothy J Peters, Hugh J French, Stephen T Bradford, Ruth Pidsley, Clare Stirzaker, Hilal Varinli, Shalima Nair, Wenjia Qu, Jenny Song, Katherine A Giles, Aaron L Statham, Helen Speirs, Terence P Speed, Susan J Clark

Journal article  |  2019  |  Bioinformatics

Characterization of high TIL breast cancers reveals a prognostic and functionally distinct tissue-resident memory subpopulation

P Savas, B Virassamy, C Ye, A Salim, CP Mintoff, F Caramia, R Salgado, ZL Teo, S Dushyanthen, A Byrne, SJ Luen, SB Fox, TP Speed, LK Mackay, PJ Neeson, S Loi

Conference Proceedings  |  2019  |  Poster Discussion Abstracts

Dysregulated IL-1-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine

Man Lyang Kim, William J Martin, Gabriela Minigo, Joanne L Keeble, Alexandra L Garnham, Guido Pacini, Gordon K Smyth, Terence P Speed, Jonathan Carapetis, Ian P Wicks

Journal article  |  2018  |  Circulation

Using long-read sequencing to detect imprinted DNA methylation

Scott Gigante, Quentin Gouil, Alexis Lucattini, Andrew Keniry, Tamara Beck, Matthew Tinning, Lavinia Gordon, Chris Woodruff, Terence Speed, Marnie Blewitt, Matthew Ritchie

Journal article  |  2018

Systematic variation in the methylation of cytosines at CpG sites plays a critical role in early development of humans and other m..