Chandana Herath

ACE2: from protection of liver disease to propagation of COVID-19.

Fiona J Warner, Harinda Rajapaksha, Nicholas Shackel, Chandana B Herath

Journal article  |  2020  |  Clinical Science

Twenty years ago, the discovery of angiotensin-converting enzyme 2 (ACE2) was an important breakthrough dramatically enhancing our..

Cirrhotic portal hypertension: From pathophysiology to novel therapeutics

Lakmie S Gunarathne, Harinda Rajapaksha, Nicholas Shackel, Peter W Angus, Chandana B Herath

Journal article  |  2020  |  World Journal of Gastroenterology

Portal hypertension and bleeding from gastroesophageal varices is the major cause of morbidity and mortality in patients with cirr..

Liver-Targeted Angiotensin Converting Enzyme 2 Therapy Inhibits Chronic Biliary Fibrosis in Multiple Drug-Resistant Gene 2-Knockout Mice

Indu G Rajapaksha, Lakmie S Gunarathne, Khashayar Asadi, Sharon C Cunningham, Alexandra Sharland, Ian E Alexander, Peter W Angus, Chandana B Herath

Journal article  |  2019  |  Hepatology Communications

Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products

Dinali H Fernando, Josephine M Forbes, Peter W Angus, Chandana B Herath

Journal article  |  2019  |  International Journal of Molecular Sciences

Non-alcoholic fatty liver disease (NAFLD) affects up to 30% of the adult population and is now a major cause of liver disease-rela..

Blockade of Mas Receptor or Mas-Related G-Protein Coupled Receptor Type D Reduces Portal Pressure in Cirrhotic but Not in Non-cirrhotic Portal Hypertensive Rats

Lakmie S Gunarathne, Peter W Angus, Chandana B Herath

Journal article  |  2019  |  Frontiers in Physiology

Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation

Stephen Casey, Robert Schierwagen, Kai Yan Mak, Sabine Klein, Frank Uschner, Christian Jansen, Michael Praktiknjo, Carsten Meyer, Daniel Thomas, Chandana Herath, Robert Jones, Jonel Trebicka, Peter Angus

Journal article  |  2019  |  Journal of Clinical Medicine

Current therapies and novel approaches for biliary diseases.

Indu G Rajapaksha, Peter W Angus, Chandana B Herath

Journal article  |  2019  |  World Journal of Gastrointestinal Pathophysiology

Chronic liver diseases that inevitably lead to hepatic fibrosis, cirrhosis and/or hepatocellular carcinoma have become a major cau..

The Effects of Diabetes and High-Fat Diet on Polymodal Nociceptor and Cold Thermoreceptor Nerve Terminal Endings in the Corneal Epithelium

Abdulhakeem S Alamri, James A Brock, Chandana B Herath, Indu G Rajapaksha, Peter W Angus, Jason J Ivanusic

Journal article  |  2019  |  Investigative Ophthalmology & Visual Science

Effects of angiotensin-(1-7) and angiotensin II on vascular tone in human cirrhotic splanchnic vessels

Stephen Casey, Chandana Herath, Indu Rajapaksha, Robert Jones, Peter Angus

Journal article  |  2018  |  Peptides

The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice

Indu G Rajapaksha, Kai Y Mak, Ping Huang, Louise M Burrell, Peter W Angus, Chandana B Herath

Journal article  |  2018  |  SCIENTIFIC REPORTS