Michael Kershaw

Challenges and Opportunities for Effective Cancer Immunotherapies

Clare Y Slaney, Michael H Kershaw

Journal article  |  2020  |  Cancers

Using immunotherapy to treat cancers can be traced back to the 1890s, where a New York physician William Coley used heat-killed ba..

Tissue-specific tumour microenvironments are an emerging determinant of immunotherapy responses

Amanda J Oliver, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney

Journal article  |  2020  |  Journal of Thoracic Disease

Chimeric antigen receptor T cell therapies for thoracic cancers-challenges and opportunities

Jack D Chan, Aaron J Harrison, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney

Journal article  |  2020  |  Journal of Thoracic Disease

Cross-talk between tumors at anatomically distinct sites

Amanda J Oliver, Phillip K Darcy, Joseph A Trapani, Michael H Kershaw, Clare Y Slaney

Journal article  |  2020  |  The FEBS Journal

Cancer tissue is not homogenous, and individual metastases at different anatomical locations can differ from the primary tumor and..

Primary and metastatic breast tumors cross-talk to influence immunotherapy responses

Amanda J Oliver, Simon P Keam, Bianca von Scheidt, Damien J Zanker, Aaron J Harrison, Daniela GM Tantalo, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney

Journal article  |  2020  |  OncoImmunology

The presence of a tumor can alter host immunity systematically. The immune-tumor interaction in one site may impact the local immu..

Novel combination immunotherapy for pancreatic cancer: potent anti-tumor effects with CD40 agonist and interleukin-15 treatment

Jonas RM Van Audenaerde, Elly Marcq, Bianca von Scheidt, Ashleigh S Davey, Amanda J Oliver, Jorrit De Waele, Delphine Quatannens, Jinthe Van Loenhout, Patrick Pauwels, Geert Roeyen, Filip Lardon, Clare Y Slaney, Marc Peeters, Michael H Kershaw, Phillip K Darcy, Evelien LJM Smits

Journal article  |  2020  |  Clinical and Translational Immunology

Objectives: With the poorest 5-year survival of all cancers, improving treatment for pancreatic cancer is one of the biggest chall..

Enhancing chimeric antigen receptor T-cell immunotherapy against cancer using a nanoemulsion-based vaccine targeting cross-presenting dendritic cells

Jack D Chan, Bianca von Scheidt, Bijun Zeng, Amanda J Oliver, Ashleigh S Davey, Aesha Ali, Ranjeny Thomas, Joseph A Trapani, Phillip K Darcy, Michael H Kershaw, Riccardo Dolcetti, Clare Y Slaney

Journal article  |  2020  |  Clinical and Translational Immunology

Objectives: Adoptive transfer of chimeric antigen receptor (CAR)-modified T cells is a form of cancer immunotherapy that has achie..

Enterotoxins can support CAR T cells against solid tumors

Bianca von Scheidt, Minyu Wang, Amanda J Oliver, Jack D Chan, Metta K Jana, Aesha I Ali, Fiona Clow, John D Fraser, Kylie M Quinn, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney

Journal article  |  2019  |  Proceedings of the National Academy of Sciences of the United States of America

Enhancing CAR T cell therapy by enabling their interaction with antigen-presenting cells

CY Slaney, P Wang, JD Chan, PK Darcy, MH Kershaw

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

DEVELOPMENT OF NEXT GENERATION CAR'S TARGETING THE LEWIS Y ANTIGEN FOR THE TREATMENT OF CANCER

D Meyran, J Zhu, J Buttler, D Tantalo, M Neeson, P Ekert, M Kershaw, J Trapani, P Darcy, P Neeson

Conference Proceedings  |  2019  |  Cytotherapy