Misty Jenkins

A community-based co-designed genetic health service model for Aboriginal Australians

Imogen Elsum, Libby Massey, Callum McEwan, Desiree LaGrappe, Emma Kowal, Ravi Savarirayan, Gareth Baynam, Misty Jenkins, Gail Garvey, Margaret Kelaher

Journal article  |  2020  |  PLOS ONE

BACKGROUND: Aboriginal and Torres Strait Islander people experience a greater burden of disease and die younger than non-Indigenou..

Cellular and Molecular Mechanisms of CD8( ) T Cell Differentiation, Dysfunction and Exhaustion

Daniel J Verdon, Matthias Mulazzani, Misty R Jenkins

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

T cells follow a triphasic distinct pathway of activation, proliferation and differentiation before becoming functionally and phen..

Equitable Expanded Carrier Screening Needs Indigenous Clinical and Population Genomic Data

Simon Easteal, Ruth M Arkell, Renzo F Balboa, Shayne A Bellingham, Alex D Brown, Tom Calma, Matthew C Cook, Megan Davis, Hugh JS Dawkins, Marcel E Dinger, Michael S Dobbie, Ashley Farlow, Kylie G Gwynne, Azure Hermes, Wendy E Hoy, Misty R Jenkins, Simon H Jiang, Warren Kaplan, Stephen Leslie, Bastien Llamas, et al.

Journal article  |  2020  |  AMERICAN JOURNAL OF HUMAN GENETICS

Expanded carrier screening (ECS) for recessive monogenic diseases requires prior knowledge of genomic variation, including DNA var..

Towards Immunotherapy for Pediatric Brain Tumors

Stacie Shiqi Wang, Pratiti Bandopadhayay, Misty Rayna Jenkins

Journal article  |  2019  |  TRENDS IN IMMUNOLOGY

Pediatric brain tumors are the leading cause of childhood cancer-related death. Immunotherapy is a powerful new approach for treat..

PF568 INVESTIGATING MECHANISMS OF ELOTUZUMAB AND LENALIDOMIDE THERAPY IN MULTIPLE MYELOMA

KJ Richardson, M Robbins, NA Bezman, H Quach, SJ Harrison, MH Prince, DS Ritchie, MR Jenkins, PA Beavis, PK Darcy, PJ Neeson

Conference Proceedings  |  2019  |  HemaSphere

Human gamma delta T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation

Sneha Sant, Misty R Jenkins, Pradyot Dash, Katherine A Watson, Zhongfang Wang, Angela Pizzolla, Marios Koutsakos, Thi HO Nguyen, Martha Lappas, Jane Crowe, Tom Loudovaris, Stuart Mannering, Glen P Westall, Tom C Kotsimbos, Allen C Cheng, Linda Wakim, Peter C Doherty, Paul G Thomas, Liyen Loh, Katherine Kedzierska

Journal article  |  2019  |  CLINICAL & TRANSLATIONAL IMMUNOLOGY

Background: Although γδ T cells comprise up to 10% of human peripheral blood T cells, questions remain regarding their role in dis..

Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma

Nicholas A Gherardin, Liyen Loh, Lorenztino Admojo, Alexander J Davenport, Kelden Richardson, Amy Rogers, Phillip K Darcy, Misty R Jenkins, H Miles Prince, Simon J Harrison, Hang Quach, David P Fairlie, Katherine Kedzierska, James McCluskey, Adam P Uldrich, Paul J Neeson, David S Ritchie, Dale I Godfrey

Journal article  |  2018  |  SCIENTIFIC REPORTS

Mucosal-associated invariant T (MAIT) cells are T cells that recognise vitamin-B derivative Ag presented by the MHC-related-protei..

Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity

AJ Davenport, RS Cross, KA Watson, Y Liao, W Shi, HM Prince, PA Beavis, JA Trapani, MH Kershaw, DS Ritchie, PK Darcy, PJ Neeson, MR Jenkins

Journal article  |  2018  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chimeric antigen receptor T (CAR-T) cells are effective serial killers with a faster off-rate from dying tumor cells than CAR-T ce..

Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice

Prerak M Trivedi, Kate L Graham, Nicholas A Scott, Misty R Jenkins, Suktilang Majaw, Robyn M Sutherland, Stacey Fynch, Andrew M Lew, Christopher J Burns, Balasubramanian Krishnamurthy, Thomas C Brodnicki, Stuart I Mannering, Thomas W Kay, Helen E Thomas

Journal article  |  2017  |  DIABETES

Recent advances in immunotherapeutics have not yet changed the routine management of autoimmune type 1 diabetes. There is an oppor..

HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2( ) Tumors

Mikolaj Medon, Eva Vidacs, Stephin J Vervoort, Jason Li, Misty R Jenkins, Kelly M Ramsbottom, Joseph A Trapani, Mark J Smyth, Phillip K Darcy, Peter W Atadja, Michael A Henderson, Ricky W Johnstone, Nicole M Haynes

Journal article  |  2017  |  CANCER RESEARCH

Histone deacetylase inhibitors (HDACi) may engage host immunity as one basis for their antitumor effects. Herein, we demonstrate a..