Misty Jenkins

The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells.

Kelden Richardson, Simon P Keam, Joe Jiang Zhu, Deborah Meyran, Criselle D'Souza, Sean Macdonald, Kerry Campbell, Michael Robbins, Natalie A Bezman, Kirsten Todd, Hang Quach, David S Ritchie, Simon J Harrison, H Miles Prince, Joseph A Trapani, Misty R Jenkins, Paul A Beavis, Phillip K Darcy, Paul J Neeson

Journal article  |  2023  |  Haematologica

Patients with refractory relapsed multiple myeloma respond to combination treatment with elotuzumab and lenalidomide. The mechanis..

Human EGFRvIII chimeric antigen receptor T cells demonstrate favorable safety profile and curative responses in orthotopic glioblastoma

Rebecca C Abbott, Melinda Iliopoulos, Katherine A Watson, Valeria Arcucci, Margareta Go, Hannah E Hughes-Parry, Pete Smith, Melissa J Call, Ryan S Cross, Misty R Jenkins

Journal article  |  2023  |  CLINICAL & TRANSLATIONAL IMMUNOLOGY

OBJECTIVES: Glioblastoma is a highly aggressive and fatal brain malignancy, and effective targeted therapies are required. The com..

Investigating disparity in access to Australian clinical genetic health services for Aboriginal and Torres Strait Islander people.

Joanne Luke, Philippa Dalach, Lindsay Tuer, Ravi Savarirayan, Angeline Ferdinand, Julie McGaughran, Emma Kowal, Libby Massey, Gail Garvey, Hugh Dawkins, Misty Jenkins, Yin Paradies, Glenn Pearson, Chloe A Stutterd, Gareth Baynam, Margaret Kelaher

Journal article  |  2022  |  Nat Commun

Globally, there is a recognised need that all populations should be able to access the benefits of genomics and precision medicine..

De novo-designed transmembrane domains tune engineered receptor functions

Assaf Elazar, Nicholas J Chandler, Ashleigh S Davey, Jonathan Y Weinstein, Julie Nguyen, Raphael Trenker, Ryan S Cross, Misty R Jenkins, Melissa J Call, Matthew E Call, Sarel J Fleishman

Journal article  |  2022  |  ELIFE

De novo-designed receptor transmembrane domains (TMDs) present opportunities for precise control of cellular receptor functions. W..

To go or not to go? Biological logic gating engineered T cells

Rebecca C Abbott, Hannah E Hughes-Parry, Misty R Jenkins

Journal article  |  2022  |  JOURNAL FOR IMMUNOTHERAPY OF CANCER

Genetically engineered T cells have been successfully used in the treatment of hematological malignancies, greatly increasing both..

BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Diane Moujalled, Adam G Southon, Eiman Saleh, Kerstin Brinkmann, Francine Ke, Melinda Iliopoulos, Ryan S Cross, Misty R Jenkins, Duong Nhu, Zilu Wang, Melissa X Shi, Ruth M Kluck, Guillaume Lessene, Stephanie Grabow, Ashley Bush, Andreas Strasser

Journal article  |  2022  |  CELL DEATH AND DIFFERENTIATION

Glioblastoma multiforme (GBM) is the most common and aggressive form of brain cancer, with treatment options often constrained due..

Challenges and opportunities in 2021.

Leila Akkari, Stacey D Finley, Ping-Chih Ho, Misty Jenkins, Barbara B Maier, Nicholas McGranahan, Miriam Mutebi, Rushika M Perera, Carla Daniela Robles-Espinoza, Santosha Vardhana, Liling Wan, Meng Michelle Xu

Journal article  |  2021  |  Nat Cancer

A Novel Peptide-MHC Targeted Chimeric Antigen Receptor T Cell Forms a T Cell-like Immune Synapse

Stacie Shiqi Wang, Kylie Luong, Fiona Margaret Gracey, Shereen Jabar, Brad McColl, Ryan Stanley Cross, Misty Rayna Jenkins

Journal article  |  2021  |  BIOMEDICINES

Chimeric Antigen Receptor (CAR) T cell therapy is a promising form of adoptive cell therapy that re-engineers patient-derived T ce..

Identification and Targeting of Mutant Peptide Neoantigens in Cancer Immunotherapy

Daniel J Verdon, Misty R Jenkins

Journal article  |  2021  |  CANCERS

In recent decades, adoptive cell transfer and checkpoint blockade therapies have revolutionized immunotherapeutic approaches to ca..

"This is my boy's health! Talk straight to me!" perspectives on accessible and culturally safe care among Aboriginal and Torres Strait Islander patients of clinical genetics services

Philippa Dalach, Ravi Savarirayan, Gareth Baynam, Julie McGaughran, Emma Kowal, Libby Massey, Misty Jenkins, Yin Paradies, Margaret Kelaher

Journal article  |  2021  |  INTERNATIONAL JOURNAL FOR EQUITY IN HEALTH

BACKGROUND: Aboriginal and Torres Strait Islander people do not enjoy equal access to specialist health services that adequately m..