Yunshun Chen

A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast

Bhupinder Pal, Yunshun Chen, Francois Vaillant, Bianca D Capaldo, Rachel Joyce, Xiaoyu Song, Vanessa L Bryant, Jocelyn S Penington, Leon Di Stefano, Nina Tubau Ribera, Stephen Wilcox, Gregory B Mann, Anthony T Papenfuss, Geoffrey J Lindeman, Gordon K Smyth, Jane E Visvader

Journal article  |  2021  |  EMBO JOURNAL

To examine global changes in breast heterogeneity across different states, we determined the single-cell transcriptomes of > 340,0..

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging (vol 35, pg 618, 2019)

Anne C Rios, Bianca D Capaldo, Francois Vaillant, Bhupinder Pal, Ravian van Ineveld, Caleb A Dawson, Yunshun Chen, Emma Nolan, Nai Yang Fu, Felicity C Jackling, Sapna Devi, David Clouston, Lachlan Whitehead, Gordon K Smyth, Scott N Mueller, Geoffrey J Lindeman, Jane E Visvader

Journal article  |  2019  |  CANCER CELL

(Cancer Cell 35, 618–632.e1–e6; April 15, 2019) In the STAR Methods section of the originally published version of this article, t..

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

D Merino, TS Weber, A Serrano, F Vaillant, K Liu, B Pal, L Di Stefano, J Schreuder, D Lin, Y Chen, ML Asselin-Labat, TN Schumacher, D Cameron, GK Smyth, AT Papenfuss, GJ Lindeman, JE Visvader, SH Naik

Journal article  |  2019  |  NATURE COMMUNICATIONS

Primary triple negative breast cancers (TNBC) are prone to dissemination but sub-clonal relationships between tumors and resulting..

Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway

Clare E Weeden, Yunshun Chen, Stephen B Ma, Yifang Hu, Georg Ramm, Kate D Sutherland, Gordon K Smyth, Marie-Liesse Asselin-Labat

Journal article  |  2017  |  PLOS BIOLOGY

Lung squamous cell carcinoma (SqCC), the second most common subtype of lung cancer, is strongly associated with tobacco smoking an..