Maarten Van Den Buuse

Acute NMDA Receptor Antagonism Impairs Working Memory Performance but Not Attention in Rats-Implications for the NMDAr Hypofunction Theory of Schizophrenia

Jaime Lee, Maarten van den Buuse, Jess Nithianantharajah, Nigel C Jones

Journal article  |  2020  |  Behavioral Neuroscience

Cognitive deficits in schizophrenia, which include impairments in working memory and attention, represent some of the most disabli..

7,8-Dihydroxyflavone Enhances Cue-Conditioned Alcohol Reinstatement in Rats

Samuel J Hogarth, Elvan Djouma, Maarten van den Buuse

Journal article  |  2020  |  Brain Sciences

Alcohol use disorder (AUD) is a detrimental disease that develops through chronic ethanol exposure. Reduced brain-derived neurotro..

Sex differences in the effect of maternal immune activation on cognitive and psychosis-like behaviour in Long Evans rats

Andrea Gogos, Alyssa Sbisa, Diede Witkamp, Maarten van den Buuse

Journal article  |  2020  |  European Journal of Neuroscience

Maternal immune activation during pregnancy is associated with increased risk of development of schizophrenia in later life. There..

Involvement of brain-derived neurotrophic factor (BDNF) in the long-term memory effects of glucocorticoid stimulation during adolescence/young adulthood

Maarten van den Buuse, Laetitia Buret, Rachel Hill

Journal article  |  2020  |  Behavioural Brain Research

Brain-derived neurotrophic factor (BDNF) has been implicated in cognition and the effects of chronic stress. We have previously sh..

Neurobiology of BDNF in fear memory, sensitivity to stress, and stress-related disorders

Michael Notaras, Maarten van den Buuse

Journal article  |  2020  |  Molecular Psychiatry

Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience and antidepressant drug action, is a..

Interaction of reelin and stress on immobility in the forced swim test but not dopamine-mediated locomotor hyperactivity or prepulse inhibition disruption: Relevance to psychotic and mood disorders

Michael J Notaras, Billie Vivian, Carey Wilson, Maarten van den Buuse

Journal article  |  2020  |  Schizophrenia Research

RATIONALE: Psychotic disorders, such as schizophrenia, as well as some mood disorders, such as bipolar disorder, have been suggest..

Pharmacological Mechanisms Involved in Sensory Gating Disruption Induced by ( /-)-3,4-Methylene- Dioxymethamphetamine (MDMA): Relevance to Schizophrenia

Jaime Lee, Shane Thwaites, Andrea Gogos, Maarten van den Buuse

Journal article  |  2020  |  Brain Sciences

Sensory gating deficits have been demonstrated in schizophrenia, but the mechanisms involved remain unclear. In the present study,..

Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome.

David W Greening, Michael Notaras, Maoshan Chen, Rong Xu, Joel D Smith, Lesley Cheng, Richard J Simpson, Andrew F Hill, Maarten van den Buuse

Journal article  |  2019  |  Molecular Psychiatry

Methamphetamine (Meth) abuse has reached epidemic proportions in many countries and can induce psychotic episodes mimicking the cl..

Brain-Derived Neurotrophic Factor (BDNF): Novel Insights into Regulation and Genetic Variation

Michael Notaras, Maarten van den Buuse

Journal article  |  2019  |  The Neuroscientist

Since its discovery, brain-derived neurotrophic factor (BDNF) has spawned a literature that now spans 35 years of research. While ..

GAL(3) receptor knockout mice exhibit an alcohol-preferring phenotype

Shannyn G Genders, Karlene J Scheller, Emily J Jaehne, Bradley J Turner, Andrew J Lawrence, Susanne M Brunner, Barbara Kofler, Maarten van den Buuse, Elvan Djouma

Journal article  |  2019  |  Addiction Biology

Galanin is a neuropeptide which mediates its effects via three G-protein coupled receptors (GAL1-3 ). Administration of a GAL3 ant..