Dale Godfrey

Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2 (vol 13, 889372, 2022)

Bruce D Wines, Liriye Kurtovic, Halina M Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L Mordant, Wen Shi Lee, Nicholas A Gherardin, Sheila K Patel, Gemma E Hartley, Phillip Pymm, James P Cooney, James G Beeson, Dale I Godfrey, Louise M Burrell, Menno C van Zelm, Adam K Wheatley, Amy WW Chung, et al.

Journal article  |  2023  |  FRONTIERS IN IMMUNOLOGY

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Intratumoural administration of an NKT cell agonist with CpG promotes NKT cell infiltration associated with an enhanced antitumour response and abscopal effect

Kef K Prasit, Laura Ferrer-Font, Olivia K Burn, Regan J Anderson, Benjamin J Compton, Alfonso J Schmidt, Johannes U Mayer, Chun-Jen J Chen, Nathaniel Dasyam, David S Ritchie, Dale Godfrey, Stephen R Mattarollo, P Rod Dundar, Gavin F Painter, Ian F Hermans

Journal article  |  2022  |  ONCOIMMUNOLOGY

Intratumoural administration of unmethylated cytosine-phosphate-guanine motifs (CpG) to stimulate toll-like receptor (TLR)-9 has b..

Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2

Phillip Pymm, Samuel J Redmond, Olan Dolezal, Francesca Mordant, Ester Lopez, James P Cooney, Kathryn C Davidson, Ebene R Haycroft, Chee Wah Tan, Rebecca Seneviratna, Samantha L Grimley, Damian FJ Purcell, Stephen J Kent, Adam K Wheatley, Lin-Fa Wang, Andrew Leis, Alisa Glukhova, Marc Pellegrini, Amy W Chung, Kanta Subbarao, et al.

Journal article  |  2022  |  ISCIENCE

The development of therapeutics to prevent or treat COVID-19 remains an area of intense focus. Protein biologics, including monocl..

CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells

Michael NT Souter, Wael Awad, Shihan Li, Troi Pediongco, Bronwyn S Meehan, Lucy J Meehan, Zehua Tian, Zhe Zhao, Huimeng Wang, Adam Nelson, Jérôme Le Nours, Yogesh Khandokar, T Praveena, Jacinta Wubben, Jie Lin, Lucy C Sullivan, George Lovrecz, Jeffrey YW Mak, Ligong Liu, Lyudmila Kostenko, et al.

Journal article  |  2022  |  Journal of Experimental Medicine

Mucosal-associated invariant T (MAIT) cells detect microbial infection via recognition of riboflavin-based antigens presented by t..

Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2

Bruce D Wines, Liriye Kurtovic, Halina M Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L Mordant, Wen Shi Lee, Nicholas A Gherardin, Sheila K Patel, Gemma E Hartley, Phillip Pymm, James P Cooney, James G Beeson, Dale Godfrey, Louise M Burrell, Menno C van Zelm, Adam K Wheatley, Amy W Chung, et al.

Journal article  |  2022  |  FRONTIERS IN IMMUNOLOGY

Joining a function-enhanced Fc-portion of human IgG to the SARS-CoV-2 entry receptor ACE2 produces an antiviral decoy with strain ..

A Complementary Union of SARS-CoV2 Natural and Vaccine Induced Immune Responses

Joseph Torresi, Melissa A Edeling, Terry Nolan, Dale I Godfrey

Journal article  |  2022  |  FRONTIERS IN IMMUNOLOGY

Our understanding of the immune responses that follow SARS-CoV-2 infection and vaccination has progressed considerably since the C..

The NKT cell TCR repertoire can accommodate structural modifications to the lipid and orientation of the terminal carbohydrate of iGb3

Garth Cameron, Janice MH Cheng, Dale I Godfrey, Mattie SM Timmer, Bridget L Stocker, Emma M Dangerfield

Journal article  |  2022  |  RSC ADVANCES

Isoglobotrihexosylceramide (iGb3) is a known NKT cell agonist, however the specific interactions required to trigger NKT cell TCR ..

MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT.

Hana Andrlová, Oriana Miltiadous, Anastasia I Kousa, Anqi Dai, Susan DeWolf, Sara Violante, Hee-Yon Park, Sudha Janaki-Raman, Rui Gardner, Sary El Daker, John Slingerland, Paul Giardina, Annelie Clurman, Antonio LC Gomes, Chi Nguyen, Marina Burgos da Silva, Gabriel K Armijo, Nicole Lee, Roberta Zappasodi, Ronan Chaligne, et al.

Journal article  |  2022  |  Sci Transl Med

Microbial diversity is associated with improved outcomes in recipients of allogeneic hematopoietic cell transplantation (allo-HCT)..

Nonhuman primate models for evaluation of SARS-CoV-2 vaccines

Jessica A Neil, Maryanne Griffith, Dale I Godfrey, Damian FJ Purcell, Georgia Deliyannis, David Jackson, Steve Rockman, Kanta Subbarao, Terry Nolan

Journal article  |  2022  |  EXPERT REVIEW OF VACCINES

INTRODUCTION: Evaluation of immunogenicity and efficacy in animal models provide critical data in vaccine development. Nonhuman pr..

SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

Wuji Zhang, Brendon Y Chua, Kevin J Selva, Lukasz Kedzierski, Thomas M Ashhurst, Ebene R Haycroft, Suzanne K Shoffner-Beck, Luca Hensen, David F Boyd, Fiona James, Effie Mouhtouris, Jason C Kwong, Kyra YL Chua, George Drewett, Ana Copaescu, Julie E Dobson, Louise C Rowntree, Jennifer R Habel, Lilith F Allen, Hui-Fern Koay, et al.

Journal article  |  2022  |  NATURE COMMUNICATIONS

Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying COVID-19. We examine cellular, humoral a..