Joseph Ischia

Open partial nephrectomy: current review

Ellen O'Connor, Brennan Timm, Nathan Lawrentschuk, Joseph Ischia

Journal article  |  2020  |  TRANSLATIONAL ANDROLOGY AND UROLOGY

Partial nephrectomy (PN) is increasingly considered the gold standard treatment for localized renal cell carcinomas (RCCs) where t..

MRI of the Prostate With and Without Endorectal Coil at 3 T: Correlation With Whole-Mount Histopathologic Gleason Score

Ravjot Dhatt, Stephen Choy, Steven J Co, Joseph Ischia, Piotr Kozlowski, Alison C Harris, Edward C Jones, Peter C Black, S Larry Goldenberg, Silvia D Chang

Journal article  |  2020  |  AMERICAN JOURNAL OF ROENTGENOLOGY

OBJECTIVE. The purpose of this article is to prospectively compare image quality and diagnostic accuracy of clinically significant..

The Protective Effect of Zinc Against Liver Ischaemia Reperfusion Injury in a Rat Model of Global Ischaemia

Ernest Cheung, Mehrdad Nikfarjam, Louise Jackett, Damien M Bolton, Joseph Ischia, Oneel Patel

Journal article  |  2020  |  JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY

Background: Ischaemia-reperfusion injury (IRI) is a major obstacle during liver transplantation and resection surgeries for cancer..

Experimental rat models for contrast-induced nephropathy; A comprehensive review

M Perera, J Ischia, D Bolton, A Shulkes, GS Baldwin, O Patel

Journal article  |  2020  |  Journal of Nephropathology

Contrast-induced nephropathy (CIN) is an iatrogenic disease caused by the parenteral administration of iodinated contrast media (C..

Zinc preconditioning protects against renal ischaemia-reperfusion injury through manipulation of key metabolic pathways

D O'kane, G Baldwin, D Bolton, O Patel, J Ischia

Conference Proceedings  |  2020  |  BJU INTERNATIONAL

Dual-energy computerised tomography for enhanced evaluation of renal cell carcinoma with inferior vena cava thrombus

E O'Connor, A Baker, J Ischia, D Bolton, N Lawrentschuk

Conference Proceedings  |  2020  |  BJU INTERNATIONAL

Randomised controlled trial for high-dose intravenous zinc as adjunctive therapy in SARS-CoV-2 (COVID-19) positive critically ill patients: trial protocol

Marlon Perera, John El Khoury, Vidyasagar Chinni, Damien Bolton, Liang Qu, Paul Johnson, Jason Trubiano, Christine F McDonald, Daryl Jones, Rinaldo Bellomo, Oneel Patel, Joseph Ischia

Journal article  |  2020  |  BMJ OPEN

INTRODUCTION: SARS-CoV-2 (COVID-19) has caused an international pandemic of respiratory illness, resulting in significant healthca..

Why is it worth testing the ability of zinc to protect against ischaemia reperfusion injury for human application

Joseph Ischia, Damien M Bolton, Oneel Patel

Journal article  |  2019  |  METALLOMICS

Ischaemia (interruption in the blood/oxygen supply) and subsequent damage induced by reperfusion (restoration of blood/oxygen supp..

Preconditioning against renal ischaemia reperfusion injury: the failure to translate to the clinic

Dermot O'Kane, Graham S Baldwin, Damien M Bolton, Joseph J Ischia, Oneel Patel

Journal article  |  2019  |  JOURNAL OF NEPHROLOGY

Acute kidney injury (AKI) as a result of ischaemia-reperfusion represents a major healthcare burden worldwide. Mortality rates fro..

Metformin may offer no protective effect in men undergoing external beam radiation therapy for prostate cancer

Weranja KB Ranasinghe, Scott Williams, Joseph Ischia, David Wetherell, Graham Baldwin, Arthur Shulkes, Shomik Sengupta, Damien Bolton, Oneel Patel

Conference Proceedings  |  2019  |  BJU INTERNATIONAL

OBJECTIVES: To assess whether metformin reduces radio-resistance and increases survival in men undergoing external beam radiation ..