Joseph Ischia

Why is it worth testing the ability of zinc to protect against ischaemia reperfusion injury for human application

Joseph Ischia, Damien M Bolton, Oneel Patel

Journal article  |  2019  |  Metallomics

Ischaemia (interruption in the blood/oxygen supply) and subsequent damage induced by reperfusion (restoration of blood/oxygen supp..

Preconditioning against renal ischaemia reperfusion injury: the failure to translate to the clinic

Dermot O'Kane, Graham S Baldwin, Damien M Bolton, Joseph J Ischia, Oneel Patel

Journal article  |  2019  |  Journal of Nephrology

Metformin may offer no protective effect in men undergoing external beam radiation therapy for prostate cancer

Weranja KB Ranasinghe, Scott Williams, Joseph Ischia, David Wetherell, Graham Baldwin, Arthur Shulkes, Shomik Sengupta, Damien Bolton, Oneel Patel

Conference Proceedings  |  2019  |  BJU International

Zinc protects the kidney against ischaemia-reperfusion injury: investigating the mechanisms of protection in wild-type and genetic-knockout murine strains

D O'Kane, J Du Plessis, A Shulkes, G Baldwin, D Bolton, J Ischia, O Patel

Conference Proceedings  |  2019  |  BJU INTERNATIONAL

Corrigendum to "Targeting HIF-1α to Prevent Renal Ischemia-Reperfusion Injury: Does It Work?"

Kapil Sethi, Kenny Rao, Arthur Shulkes, Graham Baldwin, Damien Bolton, Oneel Patel, Joseph Ischia

Journal article  |  2019  |  International Journal of Cell Biology

[This corrects the article DOI: 10.1155/2018/9852791.].

Zinc preconditioning protects against renal ischaemia reperfusion injury in a preclinical sheep large animal model

Dermot O'Kane, Luke Gibson, Clive N May, Justin du Plessis, Arthur Shulkes, Graham S Baldwin, Damien Bolton, Joseph Ischia, Oneel Patel

Journal article  |  2018  |  BioMetals

Trends in percutaneous renal biopsy: The evolving diagnostic pathway for the small renal mass

Marlon Perera, Nathan Papa, Joseph Ischia, Daniel Christidis, Damien Bolton, Nathan Lawrentschuk

Journal article  |  2018  |  Urology Annals

Zinc ion dyshomeostasis increases resistance of prostate cancer cells to oxidative stress via upregulation of HIF1α.

David Wetherell, Graham S Baldwin, Arthur Shulkes, Damien Bolton, Joseph Ischia, Oneel Patel

Journal article  |  2018  |  Oncotarget

Zinc ions (Zn2+) are known to influence cell survival and proliferation. However the homeostatic regulation of Zn2+ and their role..

Targeting HIF-1 α to Prevent Renal Ischemia-Reperfusion Injury: Does It Work?

K Sethi, K Rao, D Bolton, O Patel, J Ischia

Journal article  |  2018  |  International Journal of Cell Biology

Partial nephrectomy (open or minimally invasive) usually requires temporary renal arterial occlusion to limit intraoperative bleed..

Protective effect of zinc preconditioning against renal ischemia reperfusion injury is dose dependent

Kenny Rao, Kapil Sethi, Joseph Ischia, Luke Gibson, Laurence Galea, Lin Xiao, Mildred Yim, Mike Chang, Nathan Papa, Damien Bolton, Arthur Shulkes, Graham S Baldwin, Oneel Patel

Journal article  |  2017  |  PLOS ONE

Contrast Enhanced Ultrasonography in suspected renal colic: response

Frank T D'Arcy, Mike Leveridge, Dermot O'Kane, Joseph Ischia, David Webb, Damien Bolton, Nathan Lawrentschuk

Journal article  |  2016  |  European Journal of Emergency Medicine

Guideline of guidelines: follow-up after nephrectomy for renal cell carcinoma

Timothy J Williamson, John R Pearson, Joseph Ischia, Damien M Bolton, Nathan Lawrentschuk

Journal article  |  2016  |  BJU International

Renal colic: current protocols for emergency presentations

Mike Leveridge, Frank T D'Arcy, Dermot O'Kane, Joseph J Ischia, David R Webb, Damien M Bolton, Nathan Lawrentschuk

Journal article  |  2016  |  European Journal of Emergency Medicine

Consistency of written post-operative patient information for common urological procedures

Nicholas Davies, Nathan Papa, Joseph Ischia, Damien Bolton, Nathan Lawrentschuk

Journal article  |  2015  |  ANZ journal of surgery

National nephrectomy registries: Reviewing the need for population-based data

John Pearson, Timothy Williamson, Joseph Ischia, Damien M Bolton, Mark Frydenberg, Nathan Lawrentschuk

Journal article  |  2015  |  Korean Journal of Urology

Identification of binding sites for C-terminal pro-gastrin-releasing peptide (GRP)-derived peptides in renal cell carcinoma: a potential target for future therapy

Joseph Ischia, Oneel Patel, Kapil Sethi, Marianne S Nordlund, Damien Bolton, Arthur Shulkes, Graham S Baldwin

Journal article  |  2015  |  BJU International

HIF1 alpha Expression under Normoxia in Prostate Cancer-Which Pathways to Target?

Weranja KB Ranasinghe, Graham S Baldwin, Damien Bolton, Arthur Shulkes, Joseph Ischia, Oneel Patel

Journal article  |  2015  |  Journal of Urology

Intraoperative registered transrectal ultrasound guidance for robot-assisted laparoscopic radical prostatectomy.

Omid Mohareri, Joseph Ischia, Peter C Black, Caitlin Schneider, Julio Lobo, Larry Goldenberg, Septimiu E Salcudean

Journal article  |  2015  |  Journal of Urology

PURPOSE: To provide unencumbered real-time ultrasound image guidance during robot-assisted laparoscopic radical prostatectomy, we ..

Multiparametric 3D in vivo ultrasound vibroelastography imaging of prostate cancer: Preliminary results

Mehdi Moradi, S Sara Mahdavi, Guy Nir, Omid Mohareri, Anthony Koupparis, Louis-Olivier Gagnon, Ladan Fazli, Rowan G Casey, Joseph Ischia, Edward C Jones, S Larry Goldenberg, Septimiu E Salcudean

Journal article  |  2014  |  Medical Physics

Optimizing intravesical mitomycin C therapy in non-muscle-invasive bladder cancer.

Homayoun Zargar, Jonathan Aning, Joseph Ischia, Alan So, Peter Black

Journal article  |  2014  |  Nature Reviews Urology

Nearly three-quarters of all newly diagnosed urothelial cancers are non-muscle-invasive bladder cancers (NMIBCs). Although bladder..

Expression and function of gastrin-releasing peptide (GRP) in normal and cancerous urological tissues

Joseph Ischia, Oneel Patel, Damien Bolton, Arthur Shulkes, Graham S Baldwin

Journal article  |  2014  |  BJU International

The role of heat shock proteins in bladder cancer.

Joseph Ischia, Alan I So

Journal article  |  2013  |  Nature Reviews Urology

Heat shock proteins (HSPs) and clusterin (another chaperone protein with HSP-like properties) are present in normal cells and are ..

The promise of heat shock protein inhibitors in the treatment of castration resistant prostate cancer.

Joseph Ischia, Fred Saad, Martin Gleave

Journal article  |  2013  |  Current Opinion in Urology

PURPOSE OF REVIEW: To present the recent advances in novel agents that target heat shock proteins (Hsps) to treat or delay the dev..

Radical prostatectomy in high-risk prostate cancer.

Joseph Ischia, Martin Gleave

Journal article  |  2013  |  International Journal of Urology

One consistent finding in the studies regarding treating men with prostate cancer is that men with high-risk disease have the most..