Lukasz Kedzierski

In Semliki Forest virus encephalitis, suppressor of cytokine signaling 4 (SOCS4) is an essential modulator of immune responses that mediates the balance between immunopathology and virus clearance

Lukasz Kedzierski, Abigail Er Qi Tan, Isabelle Jia Hui Foo, Divya Narayanan, Nagaraj Moily, Hayley A McQuilten, Sandra E Nicholson, John K Fazakerley

Journal article  |  2023  |  IMMUNOLOGY AND CELL BIOLOGY

Central nervous system virus infections are a major cause of morbidity and mortality worldwide and a significant global public hea..

Prospective comprehensive profiling of immune responses to COVID-19 vaccination in patients on zanubrutinib therapy.

Thi HO Nguyen, Chhay Lim, Masa Lasica, Ashley Whitechurch, Surekha Tennakoon, Natalie R Saunders, Lilith F Allen, Louise C Rowntree, Brendon Y Chua, Lukasz Kedzierski, Hyon-Xhi Tan, Adam K Wheatley, Stephen J Kent, Theo Karapanagiotidis, Suellen Nicholson, Deborah A Williamson, Monica A Slavin, Constantine S Tam, Katherine Kedzierska, Benjamin W Teh

Journal article  |  2023  |  EJHaem

Zanubrutinib-treated and treatment-naïve patients with chronic lymphocytic leukaemia (CLL) or Waldenstrom's macroglobulinaemia wer..

Suppressor of Cytokine Signalling 5 (SOCS5) Modulates Inflammatory Responses during Alphavirus Infection

Lukasz Kedzierski, Abigail Er Qi Tan, Isabelle Jia Hui Foo, Sandra E Nicholson, John K Fazakerley

Journal article  |  2022  |  VIRUSES-BASEL

CNS viral infections are one of the major causes of morbidity and mortality worldwide and a significant global public health conce..

SARS-CoV-2-specific T cell memory with common TCR alpha beta motifs is established in unvaccinated children who seroconvert after infection

Louise C Rowntree, Thi HO Nguyen, Lukasz Kedzierski, Melanie R Neeland, Jan Petersen, Jeremy Chase Crawford, Lilith F Allen, E Bridie Clemens, Brendon Chua, Hayley A McQuilten, Anastasia A Minervina, Mikhail Pogorelyy, Priyanka Chaurasia, Hyon-Xhi Tan, Adam K Wheatley, Xiaoxiao Jia, Fatima Amanat, Florian Krammer, E Kaitlynn Allen, Sabrina Sonda, et al.

Journal article  |  2022  |  IMMUNITY

As the establishment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell memory in children remains la..

Immature Brain Cortical Neurons Have Low Transcriptional Competence to Activate Antiviral Defences and Control RNA Virus Infections

Divya Narayanan, Nagaraj Moily, Hayley A McQuilten, Katherine Kedzierska, Jason M Mackenzie, Lukasz Kedzierski, John K Fazakerley

Journal article  |  2022  |  JOURNAL OF INNATE IMMUNITY

Virus infections of the central nervous system (CNS) cause important diseases of humans and animals. As in other tissues, innate a..

SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

Wuji Zhang, Brendon Y Chua, Kevin J Selva, Lukasz Kedzierski, Thomas M Ashhurst, Ebene R Haycroft, Suzanne K Shoffner-Beck, Luca Hensen, David F Boyd, Fiona James, Effie Mouhtouris, Jason C Kwong, Kyra YL Chua, George Drewett, Ana Copaescu, Julie E Dobson, Louise C Rowntree, Jennifer R Habel, Lilith F Allen, Hui-Fern Koay, et al.

Journal article  |  2022  |  NATURE COMMUNICATIONS

Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying COVID-19. We examine cellular, humoral a..

Tu1544: HUMORAL AND T CELL RESPONSES TO COVID-19 VACCINATION IN INFLAMMATORY BOWEL DISEASE

Eva Zhang, Katherine Bond, Oanh Nguyen, Lukasz Kedzierski, Lilith F Allen, Katherine Kedzierka, Britt Christensen

Journal article  |  2022  |  Gastroenterology

Robust and prototypical immune responses towards COVID-19 BNT162b2 vaccines in Indigenous people

Wuji Zhang, Lukasz Kedzierski, Brendon Y Chua, Adam K Wheatley, Louise Rowntree, Lilith Allen, Jan Petersen, Priyanka Chaurasia, Robert Mettelman, Adrian Miller, Paul G Thomas, Jamie Rossjohn, Kanta Subbarao, Stephen J Kent, Jane Nelson, Jane Davies, Thi HO Nguyen, Katherine Kedzierska

Journal article  |  2022  |  The Journal of Immunology

Abstract SARS-CoV-2 has led to >270 million infections and >5 million deaths globally. Indigenous people are ..

P092 Humoral and T cell responses to COVID-19 vaccination in IBD

E Zhang, K Bond, O Nguyen, L Allen, L Kedzierski, K Kedzierka, B Christensen

Journal article  |  2022  |  Journal of Crohn's and Colitis

Abstract Background The characteristics of SARS-CoV-2 vaccine-induced immunity..

Humoral and T cell responses to COVID-19 vaccination in IBD

E Zhang, K Bond, O Nguyen, L Allen, L Kedzierski, K Kedzierka, B Christensen

Conference Proceedings  |  2022  |  JOURNAL OF CROHNS & COLITIS