Ashley Dunn

Joseph F. Sambrook (1939-2019) obituary

Ashley Dunn, Ricky W Johnstone, Bruce Stillman

Journal article  |  2019  |  NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor

Nicholas M Gough, Jill Gough, Donald Metcalf, Anne Kelso, Dianne Grail, Nicos A Nicola, Antony W Burgess, Ashley R Dunn

Journal article  |  2017  |  JOURNAL OF IMMUNOLOGY

cDNA clones specifying the murine granulocyte-macrophage colony stimulating factor have been isolated. This haematopoietic growth ..

Donald Metcalf (1929-2014) Obituary

Douglas J Hilton, Nicos A Nicola, Warren S Alexander, Andrew W Roberts, Ashley R Dunn

Journal article  |  2015  |  CELL

Mice lacking both G-CSF and IL-6 are more susceptible to Candida albicans infection: Critical role of neutrophils in defense against Candida albicans

Sunanda Basu, Cathy Quilici, Hui-Hua Zhang, Dianne Grail, Ashley R Dunn

Journal article  |  2008  |  GROWTH FACTORS

Neutrophils play an important role in the host's defense against infection with various pathogenic organisms. Granulocyte colony s..

Macrophage-colony stimulating factor is required for the production of neutrophil-promoting activity by mouse embryo fibroblasts deficient in G-CSF and GM-CSF

Hui Hua Zhang, Sunanda Basu, Fenqiang Wu, C Glenn Begley, Christiaan JM Saris, Ashley R Dunn, Antony W Burgess, Francesca Walker

Journal article  |  2007  |  JOURNAL OF LEUKOCYTE BIOLOGY

G-CSF and GM-CSF play important roles in regulating neutrophil production, survival, differentiation, and function. However, we ha..

Mice lacking three myeloid colony-stimulating factors (G-CSF, GM-CSF, and M-CSF) still produce macrophages and Granulocytes and mount sterile model of peritonitis

Margaret L Hibbs, Cathy Quilici, Nicole Kountouri, John F Seymour, Jane E Armes, Antony W Burgess, Ashley R Dunn

Journal article  |  2007  |  JOURNAL OF IMMUNOLOGY

To assess the combined role of G-CSF, GM-CSF, and M-CSF in myeloid cell production, mice deficient in all three myeloid CSFs were ..

Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4( ) hemangiocytes

David K Jin, Koji Shido, Hans-Georg Kopp, Isabelle Petit, Sergey V Shmelkov, Lauren M Young, Andrea T Hooper, Hideki Amano, Scott T Avecilla, Beate Heissig, Koichi Hattori, Fan Zhang, Daniel J Hicklin, Yan Wu, Zhenping Zhu, Ashley Dunn, Hassan Salari, Zena Werb, Neil R Hackett, Ronald G Crystal, et al.

Journal article  |  2006  |  NATURE MEDICINE

The mechanisms through which hematopoietic cytokines accelerate revascularization are unknown. Here, we show that the magnitude of..

Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy

SJ Kaczmarczyk, S Andrikopoulos, J Favaloro, AA Domenighetti, A Dunn, M Ernst, D Grail, M Fodero-Tavoletti, CE Huggins, LM Delbridge, JD Zajac, J Proietto

Journal article  |  2003  |  JOURNAL OF MOLECULAR ENDOCRINOLOGY

The aim of this study was to investigate the metabolic and structural consequences of a decrease in glucose transporter-4 (GLUT4) ..

Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

ML Hibbs, KW Harder, J Armes, N Kountouri, C Quilici, F Casagranda, AR Dunn, DM Tarlinton

Journal article  |  2002  |  JOURNAL OF EXPERIMENTAL MEDICINE

Genetic ablation of the Lyn tyrosine kinase has revealed unique inhibitory roles in B lymphocyte signaling. We now report the cons..

Hematopoietic abnormalities in mice deficient in gpl130-mediated STAT signaling

BJ Jenkins, C Quilici, AW Roberts, D Grail, AR Dunn, M Ernst

Journal article  |  2002  |  EXPERIMENTAL HEMATOLOGY

OBJECTIVE: Studies on mice lacking the common receptor subunit gp130 reveal that activation of gp130-dependent signaling pathways ..