Pavel Lobachevsky

MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

Arcadi Cipponi, David L Goode, Justin Bedo, Mark J McCabe, Marina Pajic, David R Croucher, Alvaro Gonzalez Rajal, Simon R Junankar, Darren N Saunders, Pavel Lobachevsky, Anthony T Papenfuss, Danielle Nessem, Max Nobis, Sean C Warren, Paul Timpson, Mark Cowley, Ana C Vargas, Min R Qiu, Daniele G Generali, Shivakumar Keerthikumar, et al.

Journal article  |  2020  |  Science

In microorganisms, evolutionarily conserved mechanisms facilitate adaptation to harsh conditions through stress-induced mutagenesi..

A Roberts Syndrome Individual With Differential Genotoxin Sensitivity and a DNA Damage Response Defect

Michael J McKay, Jeffery Craig, Paul Kalitsis, Sergei Kozlov, Sandra Verschoor, Phillip Chen, Pavel Lobachevsky, Raja Vasireddy, Yuqian Yan, Jacinta Ryan, George McGillivray, Ravi Savarirayan, Martin F Lavin, Robert G Ramsay, Huiling Xu

Journal article  |  2019  |  International Journal of Radiation Oncology • Biology • Physics

A Functional Immune System Is Required for the Systemic Genotoxic Effects of Localized Irradiation

Pavel N Lobachevsky, Jessica Ventura, Lina Giannakandropoulou, Helen Forrester, Jason S Palazzolo, Nicole M Haynes, Andrew W Stevenson, Christopher J Hall, Joel Mason, Gerasimos Pollakis, Ioannis S Pateras, Vassilis Gorgoulis, Georgia I Terzoudi, John A Hamilton, Carl N Sprung, Alexandros G Georgakilas, Olga A Martin

Journal article  |  2019  |  International Journal of Radiation Oncology • Biology • Physics

Systemic effects of synchrotron radiation

J Ventura, CN Sprung, HB Forrester, JS Palazzolo, A Ivashkevich, AW Stevenson, CJ Hall, AG Georgakilas, PN Lobachevsky, OA Martin

Conference Proceedings  |  2019  |  Journal of Physics Conference Series

Radiation Therapy Modulates DNA Repair Efficiency in Peripheral Blood Mononuclear Cells of Patients With Non-Small Cell Lung Cancer

Xiaoyu Yin, Joel Mason, Pavel N Lobachevsky, Laura Munforte, Lisa Selbie, David L Ball, Roger F Martin, Trevor Leong, Shankar Siva, Olga A Martin

Journal article  |  2019  |  International Journal of Radiation Oncology*Biology*Physics

A Bayesian Approach for Prediction of Patient Radiosensitivity

Alan Herschtal, Roger F Martin, Trevor Leong, Pavel Lobachevsky, Olga A Martin

Journal article  |  2018  |  International Journal of Radiation Oncology*Biology*Physics

Localized synchrotron radiation in mice induces persistent systemic genotoxic events mediated by the functional immune system

Jessica Ventura, Pavel Lobachevsky, Jason Palazzolo, Helen Forrester, Nicole Haynes, Alesia Ivashkevich, Andrew Stevenson, Christopher Hall, Vassilis Gorgoulis, John Hamilton, Alexandros Georgakilas, Calr Sprung, Olga A Martin

Conference Proceedings  |  2018  |  Clinical Research (Excluding Clinical Trials)

Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses

Jessica Ventura, Pavel N Lobachevsky, Jason S Palazzolo, Helen Forrester, Nicole M Haynes, Alesia Ivashkevich, Andrew W Stevenson, Christopher J Hall, Andreas Ntargaras, Vasilis Kotsaris, Gerasimos Ch Pollakis, Gianna Potsi, Konstantinos Skordylis, Georgia Terzoudi, Ioannis S Pateras, Vassilis G Gorgoulis, Alexandros G Georgakilas, Carl N Sprung, Olga A Martin

Journal article  |  2017  |  Cancer Research

Compromized DNA repair as a basis for identification of cancer radiotherapy patients with extreme radiosensitivity

Pavel Lobachevsky, Trevor Leong, Patricia Daly, Jai Smith, Nickala Best, Jonathan Tomaszewski, Ella R Thompson, Na Li, Ian G Campbell, Roger F Martin, Olga A Martin

Journal article  |  2016  |  Cancer Letters

Triple targeting of Auger emitters using octreotate conjugated to a DNA-binding ligand and a nuclear localizing signal

John A Violet, Gabriella Farrugia, Colin Skene, Jonathan White, Pavel Lobachevsky, Roger Martin

Journal article  |  2016  |  International Journal of Radiation Biology