Michael Hofman

ENZA-p trial protocol: a randomized phase II trial using prostate-specific membrane antigen as a therapeutic target and prognostic indicator in men with metastatic castration-resistant prostate cancer treated with enzalutamide (ANZUP 1901)

Louise Emmett, Shalini Subramaniam, Anthony M Joshua, Megan Crumbaker, Andrew Martin, Alison Y Zhang, Nisha Rana, Ailsa Langford, Jenna Mitchell, Sonia Yip, Roslyn Francis, Michael S Hofman, Shahneen Sandhu, Arun Azad, Craig Gedye, Margaret McJannett, Martin R Stockler, Ian D Davis

Journal article  |  2021  |  BJU INTERNATIONAL

OBJECTIVES: To determine the activity and safety of lutetium-177 (177 Lu)-prostate-specific membrane antigen (PSMA)-617 in men wit..

Preclinical Evidence of the Efficacy of Lewis Y Car T Cells in Patient-Derived Models of Prostate Cancer

Gail Petuna Risbridger, Laura Helen Porter, Joe Zhu, David Byrne, Natalie Lister, Arun Azad, Michael Hofman, Ian Vela, Renea A Taylor, Paul Neeson, Phil Darcy, Joseph Trapani

Conference Proceedings  |  2021  |  Journal of the Endocrine Society

Abstract Chimeric antigen receptor T (CAR T) cell therapy is an adoptive immunotherapy that has led to new treatmen..

UpFrontPSMA: a randomized phase 2 study of sequential Lu-177-PSMA-617 and docetaxel vs docetaxel in metastatic hormone-naive prostate cancer (clinical trial protocol)

Nattakorn Dhiantravan, Louise Emmett, Anthony M Joshua, David A Pattison, Roslyn J Francis, Scott Williams, Shahneen Sandhu, Ian D Davis, Ian Vela, Nitika Neha, Mathias Bressel, Declan G Murphy, Michael S Hofman, Arun A Azad

Journal article  |  2021  |  BJU INTERNATIONAL

OBJECTIVE: To assess the activity and safety of sequential lutetium-177 (177 Lu)-PSMA-617 and docetaxel vs docetaxel on a backgrou..

Intra-patient comparison of physiologic Ga-68-PSMA-11 and F-18-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay

Medhat M Osman, Amir Iravani, Michael S Hofman, Rodney J Hicks

Journal article  |  2021  |  CANCER IMAGING

BACKGROUND: Recent studies reported metabolic uptake in at least one of the evaluated ganglia in 98.5% of patients undergoing 68Ga..

Management of Persistently Elevated Prostate-specific Antigen After Radical Prostatectomy: A Systematic Review of the Literature

Guillaume Ploussard, Nicola Fossati, Thomas Wiegel, Anthony D'Amico, Michael S Hofman, Silke Gillessen, Nicolas Mottet, Steven Joniau, Daniel E Spratt

Journal article  |  2021  |  EUROPEAN UROLOGY ONCOLOGY

CONTEXT: The prognosis and optimal management of pN0/pN1 patients with persistently elevated prostate-specific antigen (PSA) 6-8 w..

The Global Reading Room: Nuclear Medicine Imaging of Suspected Paraganglioma.

Michael S Hofman, Lizette Louw, Karel Pacak, David Taïeb

Journal article  |  2021  |  AJR Am J Roentgenol

The role of PSMA PET/CT imaging in the diagnosis, staging and restaging of prostate cancer

Dominic Bagguley, Sean Ong, James P Buteau, Sam Koschel, Nattakorn Dhiantravan, Michael S Hofman, Louise Emmett, Declan G Murphy, Nathan Lawrentschuk

Journal article  |  2021  |  FUTURE ONCOLOGY

Prostate-specific membrane antigen (PSMA) PET/CT is a novel imaging technique for the detection and staging of either primary or r..

Automated assessment of functional lung imaging with Ga-68-ventilation/perfusion PET/CT using iterative histogram analysis

Lachlan McIntosh, Price Jackson, Nicholas Hardcastle, Mathias Bressel, Tomas Kron, Jason W Callahan, Daniel Steinfort, Nicholas Bucknell, Michael S Hofman, Shankar Siva

Journal article  |  2021  |  EJNMMI PHYSICS

PURPOSE: Functional lung mapping from Ga68-ventilation/perfusion (V/Q) PET/CT, which has been shown to correlate with pulmonary fu..

Positron Emission Tomography and Whole-body Magnetic Resonance Imaging for Metastasis-directed Therapy in Hormone-sensitive Oligometastatic Prostate Cancer After Primary Radical Treatment: A Systematic Review.

Andrea Farolfi, Boris Hadaschik, Freddie C Hamdy, Ken Herrmann, Michael S Hofman, Declan G Murphy, Piet Ost, Anwar R Padhani, Stefano Fanti

Journal article  |  2021  |  Eur Urol Oncol

CONTEXT: Next-generation imaging includes positron emission tomography (PET) imaging and whole-body magnetic resonance imaging (wb..

18F-Fluorothymidine PET for Functional Response Assessment Following Radiation Therapy for Extramedullary Hematopoiesis.

Belinda A Campbell, Jason Callahan, Merrole Cole-Sinclair, Michael MacManus, Michael S Hofman

Journal article  |  2021  |  Clin Nucl Med

ABSTRACT: As a marker of cellular proliferation, 18F-fluorothymidine (FLT) PET can detect the distribution of proliferating hemato..