Michael Wilson

Cellular Microenvironment Stiffness Regulates Eicosanoid Production and Signaling Pathways

Asres Berhan, Trudi Harris, Jade Jaffar, Fernando Jativa, Shenna Langenbach, Ingrid Loennstedt, Monther Alhamdoosh, Milica Ng, Peter Lee, Glen Westall, Nick Wilson, Michael Wilson, Alastair G Stewart

Journal article  |  2020  |  AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pathological changes in the biomechanical environment are implicated in the progression of idiopathic pulmonary fibrosis (IPF). St..

Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans

Jarny Choi, Tracey M Baldwin, Mae Wong, Jessica E Bolden, Kirsten A Fairfax, Erin C Lucas, Rebecca Cole, Christine Biben, Clare Morgan, Kerry A Ramsay, Ashley P Ng, Maria Kauppi, Lynn M Corcoran, Wei Shi, Nick Wilson, Michael J Wilson, Warren S Alexander, Douglas J Hilton, Carolyn A de Graaf

Journal article  |  2019  |  NUCLEIC ACIDS RESEARCH

During haematopoiesis, haematopoietic stem cells differentiate into restricted potential progenitors before maturing into the many..

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis

Ian K Campbell, David Leong, Kirsten M Edwards, Veronika Rayzman, Milica Ng, Gabrielle L Goldberg, Nicholas J Wilson, Karen Scalzo-Inguanti, Charley Mackenzie-Kludas, Kate E Lawlor, Ian P Wicks, Lorena E Brown, Adriana Baz Morelli, Con Panousis, Michael J Wilson, Andrew D Nash, Brent S McKenzie, Arna E Andrews

Journal article  |  2016  |  JOURNAL OF IMMUNOLOGY

G-CSF is a hemopoietic growth factor that has a role in steady state granulopoiesis, as well as in mature neutrophil activation an..

Haemopedia: An Expression Atlas of Murine Hematopoietic Cells

Carolyn A De Graaf, Jarny Choi, Tracey M Baldwin, Jessica E Bolden, Kirsten A Fairfax, Aaron J Robinson, Christine Biben, Clare Morgan, Kerry Ramsay, Ashley P Ng, Maria Kauppi, Elizabeth A Kruse, Tobias J Sargeant, Nick Seidenman, Angela D'Amico, Marthe C D'Ombrain, Erin C Lucas, Sandra Koernig, Adriana Baz Morelli, Michael J Wilson, et al.

Journal article  |  2016  |  STEM CELL REPORTS

Hematopoiesis is a multistage process involving the differentiation of stem and progenitor cells into distinct mature cell lineage..

CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common beta chain of the IL-3, GM-CSF and IL-5 receptors

Con Panousis, Urmi Dhagat, Kirsten M Edwards, Veronika Rayzman, Matthew P Hardy, Hal Braley, Gail M Gauvreau, Timothy R Hercus, Steven Smith, Roma Sehmi, Laura McMillan, Mara Dottore, Barbara J McClure, Louis J Fabri, Gino Vairo, Angel F Lopez, Michael W Parker, Andrew D Nash, Nicholas J Wilson, Michael J Wilson, et al.

Journal article  |  2016  |  MABS

The β common-signaling cytokines interleukin (IL)-3, granulocyte-macrophage colony stimulating factor (GM-CSF) and IL-5 stimulate ..

A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk

Magnus Larsson, Veronika Rayzman, Marc W Nolte, Katrin F Nickel, Jenny Bjorkqvist, Anne Jamsa, Matthew P Hardy, Marion Fries, Stefan Schmidbauer, Patricia Hedenqvist, Michael Broome, Ingo Pragst, Gerhard Dickneite, Michael J Wilson, Andrew D Nash, Con Panousis, Thomas Renne

Journal article  |  2014  |  SCIENCE TRANSLATIONAL MEDICINE

Currently used anticoagulants prevent thrombosis but increase bleeding. We show an anticoagulation therapy without bleeding risk b..