Bruno Catimel

MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors

Anuratha Sakthianandeswaren, Marie J Parsons, Dmitri Mouradov, Ruth N MacKinnon, Bruno Catimel, Sheng Liu, Michelle Palmieri, Christopher Love, Robert N Jorissen, Shan Li, Lachlan Whitehead, Tracy L Putoczki, Adele Preaudet, Cary Tsui, Cameron J Nowell, Robyn L Ward, Nicholas J Hawkins, Jayesh Desai, Peter Gibbs, Matthias Ernst, et al.

Journal article  |  2018  |  Cancer Discovery

Development of monoclonal anti-PDGF-CC antibodies as tools for investigating human tissue expression and for blocking PDGF-CC induced PDGFR alpha signalling in vivo

Hong Li, Manuel Zeitelhofer, Ingrid Nilsson, Xicong Liu, Laura Allan, Benjamin Gloria, Angelo Perani, Carmel Murone, Bruno Catimel, A Munro Neville, Fiona E Scott, Andrew M Scott, Ulf Eriksson

Journal article  |  2018  |  PLOS ONE

Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine

Gahana Advani, Ya Chee Lim, Bruno Catimel, Daisy Sio Seng Lio, Nadia LY Ng, Anderly C Chueh, Mai Tran, Mohd Ishtiaq Anasir, Heather Verkade, Hong-Jian Zhu, Benjamin E Turk, Thomas E Smithgall, Ching-Seng Ang, Michael Griffin, Heung-Chin Cheng

Journal article  |  2017  |  Cell Communication and Signaling

Cross-species analysis of Fc engineered anti-Lewis-Y human IgG1 variants in human neonatal receptor transgenic mice reveal importance of S254 and Y436 in binding human neonatal Fc receptor

Ingrid JG Burvenich, William Farrugia, Fook T Lee, Bruno Catimel, Zhanqi Liu, Dahna Makris, Diana Cao, Graeme J O'Keefe, Martin W Brechbiel, Dylan King, Violeta Spirkoska, Laura C Allan, Paul A Ramsland, Andrew M Scott

Journal article  |  2016  |  mAbs

Synthesis of a Tethered myo-Inositol (1,3,4,5,6)Pentakisphosphate (IP5) Derivative as a Probe for Biological Studies

Mark Gregory, Bruno Catimel, Meng-Xin Yin, Melanie Condron, Antony W Burgess, Andrew B Holmes

Journal article  |  2016  |  Synlett

The C-terminal tail inhibitory phosphorylation sites of PTEN regulate its intrinsic catalytic activity and the kinetics of its binding to phosphatidylinositol-4,5-bisphosphate

Yeong-Chit Joel Chia, Bruno Catimel, Daisy Sio Seng Lio, Ching-Seng Ang, Benjamin Peng, Hong Wu, Hong-Jian Zhu, Heung-Chin Cheng

Journal article  |  2015  |  Archives of Biochemistry and Biophysics

Plasmodium falciparum coronin organizes arrays of parallel actin filaments potentially guiding directional motility in invasive malaria parasites

Maya A Olshina, Fiona Angrisano, Danushka S Marapana, David T Riglar, Kartik Bane, Wilson Wong, Bruno Catimel, Meng-Xin Yin, Andrew B Holmes, Friedrich Frischknecht, David R Kovar, Jake Baum

Journal article  |  2015  |  Malaria Journal

Synthesis of Highly Water-Soluble Adamantyl Phosphoinositide Derivatives

Mark Gregory, Meng-Xin Yin, Malcolm J McConville, Eleanor Williams, Alex N Bullock, Stuart J Conway, Antony W Burgess, Bruno Catimel, Andrew B Holmes

Journal article  |  2015  |  Australian Journal of Chemistry

Activation of Src family tyrosine kinases by ferric ions

Graham S Baldwin, Daisy Sio-Seng Lio, Audrey Ferrand, Bruno Catimel, B Philip Shehan, Raymond S Norton, Heung-Chin Cheng

Journal article  |  2014  |  Biochimica et Biophysica Acta-Protein Structure and Molecular Enzymology

A Mechanism for Actin Filament Severing by Malaria Parasite Actin Depolymerizing Factor 1 via a Low Affinity Binding Interface

Wilson Wong, Andrew I Webb, Maya A Olshina, Giuseppe Infusini, Yan Hong Tan, Eric Hanssen, Bruno Catimel, Cristian Suarez, Melanie Condron, Fiona Angrisano, Thomas Neb, David R Kovar, Jake Baum

Journal article  |  2014  |  Journal of Biological Chemistry

Defining the Substrate Specificity Determinants Recognized by the Active Site of C-Terminal Src Kinase-Homologous Kinase (CHK) and Identification of beta-Synuclein as a Potential CHK Physiological Substrate

Kim K Ia, Grace R Jeschke, Yang Deng, Mohd Aizuddin Kamaruddin, Nicholas A Williamson, Denis B Scanlon, Janetta G Culvenor, Mohammed Iqbal Hossain, Anthony W Purcell, Sheng Liu, Hong-Jian Zhu, Bruno Catimel, Benjamin E Turk, Heung-Chin Cheng

Journal article  |  2011  |  Biochemistry

Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1

Wilson Wong, Colleen T Skau, Danushka S Marapana, Eric Hanssen, Nicole L Taylor, David T Riglar, Elizabeth S Zuccala, Fiona Angrisano, Heather Lewis, Bruno Catimel, Oliver B Clarke, Nadia J Kershaw, Matthew A Perugini, David R Kovar, Jacqueline M Gulbis, Jake Baum

Journal article  |  2011  |  Proceedings of the National Academy of Sciences of the United States of America

Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide

Kevin RW Ngoei, Bruno Catimel, Nicole Church, Daisy S Lio, Con Dogovski, Matthew A Perugini, Paul M Watt, Heung-Chin Cheng, Dominic CH Ng, Marie A Bogoyevitch

Journal article  |  2011  |  Biochemical Journal

Analysis of cellular phosphatidylinositol (3,4,5)-trisphosphate levels and distribution using confocal fluorescent microscopy

Michelle Palmieri, Cameron J Nowell, Melanie Condron, James Gardiner, Andrew B Holmes, Jayesh Desai, Antony W Burgess, Bruno Catimel

Journal article  |  2010  |  Analytical Biochemistry

Synthesis and biological evaluation of phosphatidylinositol phosphate affinity probes

Stuart J Conway, James Gardiner, Simon JA Grove, Melloney K Johns, Ze-Yi Lim, Gavin F Painter, Diane EJE Robinson, Christine Schieber, Jan W Thuring, Leon S-M Wong, Meng-Xin Yin, Antony W Burgess, Bruno Catimel, Phillip T Hawkins, Nicholas T Ktistakis, Leonard R Stephens, Andrew B Holmes

Journal article  |  2010  |  Organic & Biomolecular Chemistry

PI(3,4,5)P3 Interactome

Bruno Catimel, Meng-Xin Yin, Christine Schieber, Melanie Condron, Heather Patsiouras, Jenny Catimel, Diane EJE Robinson, Leon S-M Wong, Edouard C Nice, Andrew B Holmes, Antony W Burgess

Journal article  |  2009  |  Journal of Proteome Research

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR

Thomas PJ Garrett, Antony W Burgess, Hui K Gan, Rod B Luwor, Glenn Cartwright, Francesca Walker, Suzanne G Orchard, Andrew HA Clayton, Edouard C Nice, Julie Rothacker, Bruno Catimel, Webster K Cavenee, Lloyd J Old, Elisabeth Stockert, Gerd Ritter, Timothy E Adams, Peter A Hoyne, K Dane Wittrup, Ginger Chao, Jennifer R Cochran, et al.

Journal article  |  2009  |  Proceedings of the National Academy of Sciences of the United States of America

The PI(3,5)P2 and PI(4,5)P2 Interactomes

Bruno Cadmel, Christine Schleber, Melanie Condron, Heather Patsiouras, Lisa Connolly, Jenny Catimel, Edouard C Nice, Antony W Burgess, Andrew B Holmes

Journal article  |  2008  |  Journal of Proteome Research

Recruitment of adenomatous polyposis coli and beta-catenin to axin-puncta

MC Faux, JL Coates, B Catimel, S Cody, AHA Clayton, MJ Layton, AW Burgess

Journal article  |  2008  |  Oncogene

Use of multidimensional separation protocols for the purification of trace components in complex biological samples for proteomics analysis

EC Nice, J Rothacker, J Weinstock, L Lim, B Catimel

Journal article  |  2007  |  Journal of Chromatography A

Use of multidimensional separation protocols for the purification of trace components in complex biological samples for proteomics analysis

EC Nice, J Rothacker, J Weinstock, L Lim, B Catimel

Journal article  |  2007  |  Journal of Chromatography A

The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins

Laurence Goffin, Sadanand Vodala, Christine Fraser, Joanne Ryan, Mark Timms, Sarina Meusburger, Bruno Catimel, Edouard C Nice, Pamela A Silver, Chong-Yun Xiao, David A Jans, Mary-Jane H Gething

Journal article  |  2006  |  Molecular Biology of the Cell

In situ phosphorylation of immobilized receptors on biosensor surfaces: Application to E-cadherin/beta-catenin interactions

Bruno Catimel, Meredith Layton, Nicole Church, Janine Ross, Melanie Condron, Maree Faux, Richard J Simpson, Antony W Burgess, Edouard C Nice

Journal article  |  2006  |  Analytical Biochemistry

In situ phosphorylation of immobilized receptors on biosensor surfaces: Application to E-cadherin/β-catenin interactions

Bruno Catimel, Meredith Layton, Nicole Church, Janine Ross, Melanie Condron, Maree Faux, Richard J Simpson, Antony W Burgess, Edouard C Nice

Journal article  |  2006  |  Analytical Biochemistry

Purification and characterization of a high specificity polyclonal antibody to the adenomatous polyposis coli tumour suppressor protein

Bruno Catimel, Edouard C Nice, Maria Karrlander, Janine Ross, Jenny Catimel, Antony W Burgess, Maree Faux

Journal article  |  2006  |  Biomedical Chromatography

An automated peptide and protein thiazolidine coupling chemistry for biosensor immobilization giving a unique N-terminal orientation

JD Wade, K Hojo, K Kawasaki, TG Johns, B Catimel, J Rothacker, EC Nice

Journal article  |  2006  |  Analytical Biochemistry

Biosensor-based micro-affinity purification for the proteomic analysis of protein complexes

B Catimel, J Rothacker, J Catimel, M Faux, J Ross, L Connolly, A Clippingdale, AW Burgess, E Nice

Journal article  |  2005  |  Journal of Proteome Research

A cellular deficiency of gangliosides causes hypersensitivity to Clostridium perfringens phospholipase C

M Flores-Diaz, A Alape-Giron, G Clark, B Catimel, Y Hirabayashi, E Nice, JM Gutierrez, R Titball

Journal article  |  2005  |  Journal of Biological Chemistry

Affinity-Based Biosensors, Microarrays and Proteomics

E Nice, B Catimel

Book Chapter  |  2004

A binding motif for Siah ubiquitin ligase

CM House, IJ Frew, HL Huang, G Wiche, N Traficante, E Nice, B Catimel, DDL Bowtell

Journal article  |  2003  |  Proceedings of the National Academy of Sciences of the United States of America

The use of coiled-coil interactions for the analysis and micropreparative isolation of adenomatous polyposis coli protein complexes

B Catimel, MC Faux, M Nerrie, J Rothacker, L Otvos, JD Wade, EC Nice, AW Burgess

Journal article  |  2001  |  Journal of Peptide Research

The use of biosensors for microaffinity purification: an integrated approach to proteomics

B Catimel, J Rothacker, E Nice

Journal article  |  2001  |  Journal of Biochemical and Biophysical Methods

Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3

T Makinen, T Veikkola, S Mustjoki, T Karpanen, B Catimel, EC Nice, L Wise, A Mercer, H Kowalski, D Kerjaschki, SA Stacker, MG Achen, K Alitalo

Journal article  |  2001  |  EMBO Journal

Structural and biosensor analyses of a synthetic biotinylated peptide probe for the isolation of adenomatous polyposis coli tumor suppressor protein complexes

JD Wade, B Catimel, MC Faux, AW Burgess, E Nice, L Otvos

Journal article  |  2001  |  Journal of Peptide Research

The specificity of receptor binding by vascular endothelial growth factor-D is different in mouse and man

ME Baldwin, B Catimel, EC Nice, S Roufail, NE Hall, KL Stenvers, MJ Karkkainen, K Alitalo, SA Stacker, MG Achen

Journal article  |  2001  |  Journal of Biological Chemistry

Specific localization, gamma camera imaging, and intracellular trafficking of radiolabelled chimeric anti-G(D3) ganglioside monoclonal antibody KM871 in SK-MEL-28 melanoma xenografts

FT Lee, A Rigopoulos, C Hall, K Clarke, SH Cody, FE Smyth, ZQ Liu, MW Brechbiel, N Hanai, EC Nice, B Catimel, AW Burgess, S Welt, G Ritter, LJ Old, AM Scott

Journal article  |  2001  |  Cancer Research

Synthesis, conformational studies and biological activity of N-alpha-mono-biotinylated rat relaxin

MN Mathieu, JD Wade, B Catimel, CP Bond, EC Nice, RJ Summers, L Otvos, GW Tregear

Journal article  |  2001  |  Journal of Peptide Research

Targeting properties of an anti-CD16/anti-CD30 bispecific: antibody in an in vivo system

C Renner, I Stehle, FT Lee, C Hall, B Catimel, EC Nice, A Mountain, A Rigopoulos, MW Brechbiel, M Pfreundschuh, AM Scott

Journal article  |  2001  |  Cancer Immunology, Immunotherapy

Design of inhibitors of Ras-Raf interaction using a computational combinatorial algorithm

J Zeng, T Nheu, A Zorzet, B Catimel, E Nice, H Maruta, AW Burgess, HR Treutlein

Journal article  |  2001  |  Protein Engineering

The use of a synthetic biotinylaged peptide probe for the isolation of adenoatous polyposis coli (APC) tumur suppressor protein complexes.

BL CATIMEL, JDC WADE, M FAUX, AW BURGESS, L OTVOS, EC NICE

Conference Proceedings  |  2001  |  Peptides. The Wave of the Future.

Use of thiazolidine-mediated ligation for site specific biotinylation of mouse EGF for biosensor immobilisation

JD Wade, T Domagala, J Rothacker, B Catimel, E Nice

Conference Proceedings  |  2001  |  Letters in Peptide Science

c-Raf-1 RBD associates with a subset of active v-H-Ras

M Fridman, F Walker, B Catimel, T Domagala, E Nice, A Burgess

Journal article  |  2000  |  Biochemistry

Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells

CN Johnstone, NC Tebbutt, HE Abud, SJ White, KL Stenvers, NE Hall, SH Cody, RH Whitehead, B Catimel, EC Nice, AW Burgess, JK Heath

Journal article  |  2000  |  American Journal of Physiology-Gastrointestinal and Liver Physiology

Monoclonal antibodies to vascular endothelial growth factor-D block its interactions with both VEGF receptor-2 and VEGF receptor-3

MG Achen, S Roufail, T Domagala, B Catimel, EC Nice, DM Geleick, R Murphy, AM Scott, C Caesar, T Makinen, K Alitalo, SA Stacker

Journal article  |  2000  |  European Journal of Biochemistry

Micropreparative ligand fishing with a cuvette-based optical mirror resonance biosensor

B Catimel, J Weinstock, M Nerrie, T Domagala, EC Nice

Journal article  |  2000  |  Journal of Chromatography A

Recent applications of instrumental biosensors for protein and peptide structure-function studies

B Catimel, T Domagala, M Nerrie, J Weinstock, S White, H Abud, J Heath, E Nice

Journal article  |  1999  |  Protein and Peptide Letters

Instrumental biosensors: new perspectives for the analysis of biomolecular interactions

EC Nice, B Catimel

Journal article  |  1999  |  BioEssays

Mutagenesis and selection of PDZ domains that bind new protein targets

S Schneider, M Buchert, O Georgiev, B Catimel, M Halford, SA Stacker, T Baechi, K Moelling, CM Hovens

Journal article  |  1999  |  Nature Biotechnology

PDZ domains are a recently characterized protein-recognition module. In most cases, PDZ domains bind to the C-terminal end of targ..

Direct immobilization of gangliosides onto gold-carboxymethyldextran sensor surfaces by hydrophobic interaction: applications to antibody characterization

B Catimel, AM Scott, FT Lee, N Hanai, G Ritter, S Welt, LJ Old, AW Burgess, EC Nice

Journal article  |  1998  |  Glycobiology

Micro-sequencing strategies for the human A33 antigen, a novel surface glycoprotein of human gastrointestinal epithelium

RL Moritz, G Ritter, B Catimel, LS Cohen, S Welt, LJ Old, AW Burgess, EC Nice, RJ Simpson

Journal article  |  1998  |  Journal of Chromatography A

Characterization of posttranslational modifications of human A33 antigen, a novel palmitoylated surface glycoprotein of human gastrointestinal epithelium

G Ritter, LS Cohen, EC Nice, B Catimel, AW Burgess, RL Moritz, H Ji, JK Heath, SJ White, S Welt, LJ Old, RJ Simpson

Journal article  |  1997  |  Biochemical and Biophysical Research Communications

Kinetic analysis of the interaction between the monoclonal antibody A33 and its colonic epithelial antigen by the use of an optical biosensor - A comparison of immobilisation strategies

B Catimel, M Nerrie, FT Lee, AM Scott, G Ritter, S Welt, LJ Old, AW Burgess, EC Nice

Conference Proceedings  |  1997  |  Journal of Chromatography A

Strategies for the identification and purification of ligands for orphan biomolecules

E Nice, B Catimel, M Lackmann, S Stacker, A Runting, A Wilks, N Nicola, A Burgess

Journal article  |  1997  |  Letters in Peptide Science

Electrophoretic analysis of the novel antigen for the gastrointestinal-specific monoclonal antibody, A33

H Ji, RL Moritz, GE Reid, G Ritter, B Catimel, E Nice, JK Heath, SJ White, S Welt, LJ Old, AW Burgess, RJ Simpson

Journal article  |  1997  |  Electrophoresis

The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily

JK Heath, SJ White, CN Johnstone, B Catimel, RJ Simpson, RL Moritz, GF Tu, H Ji, RH Whitehead, LC Groenen, AM Scott, G Ritter, L Cohen, S Welt, LJ Old, EC Nice, AW Burgess

Journal article  |  1997  |  Proceedings of the National Academy of Sciences

Strategies for the identification and purification of ligands for orphan biomolecules

E Nice, B Catimel, M Lackmann, S Stacker, A Runting, A Wilks, N Nicola, A Burgess

Journal article  |  1997  |  International Journal of Peptide Research and Therapeutics

Purification and characterization of a novel restricted antigen expressed by normal and transformed human colonic epithelium

B Catimel, G Ritter, S Welt, LJ Old, L Cohen, MA Nerrie, SJ White, JK Heath, B Demediuk, T Domagala, FT Lee, AM Scott, GF Tu, H Ji, RL Moritz, RJ Simpson, AW Burgess, EC Nice

Journal article  |  1996  |  Journal of Biological Chemistry

Identification of a functional site on CD36 involved in the interaction between platelets and collagen

N Mercier, B Catimel, MP Reck, D Pellecchia, JL Mcgregor

Journal article  |  1995  |  Platelets

Simplified conjugation chemistry for coupling peptides to F(ab') fragments: autologous red cell agglutination assay for HIV-1 antibodies.

KM Wilson, B Catimel, KI Mitchelhill, BE Kemp

Journal article  |  1994  |  Journal of Immunological Methods

The rapid whole blood test, developed for the detection of circulating antibodies to human immunodeficiency virus type 1 (HIV-1), ..

Kinetics of the autologous red cell agglutination test.

B Catimel, KM Wilson, BE Kemp

Journal article  |  1993  |  Journal of Immunological Methods

The kinetics of the autologous red cell agglutination test for detecting circulating antibodies to HIV-1 were studied. Two monoclo..

Human platelet glycoprotein IIIb binds to thrombospondin fragments bearing the C-terminal region, and/or the type I repeats (CSVTCG motif), but not to the N-terminal heparin-binding region.

B Catimel, L Leung, H el Ghissasi, N Mercier, J McGregor

Journal article  |  1992  |  Biochemical Journal

Major blood membrane platelet glycoprotein IIIb (GPIIIb), also termed GPIV or CD365, has been identified as a receptor for thrombo..

Role of glycoprotein IIa (beta 1 subunit of very late activation antigens) in platelet functions.

S Parmentier, B Catimel, L McGregor, LL Leung, JL McGregor

Journal article  |  1991  |  Blood

Very late activation antigens (VLAs) are glycoproteins (GPs) that play a major role in platelet adhesion to extracellular matrix. ..

Separation of important new platelet glycoproteins (GPIa, GPIc, GPIc*, GPIIa and GMP-140) by f.p.l.c. Characterization by monoclonal antibodies and gas-phase sequencing.

B Catimel, S Parmentier, LL Leung, JL McGregor

Journal article  |  1991  |  Biochemical Journal

A large number of membrane glycoproteins (around 40) are present on the surface of human blood platelets. Some of these glycoprote..

Epithelial membrane glycoprotein PAS-IV is related to platelet glycoprotein IIIb binding to thrombospondin but not to malaria-infected erythrocytes.

B Catimel, JL McGregor, T Hasler, DE Greenwalt, RJ Howard, LL Leung

Journal article  |  1991  |  Blood

Glycoprotein (GP) IIIb (also termed GPIV or CD36) is an integral platelet membrane protein, and has been identified as a binding s..

Inhibition of platelet functions by a monoclonal antibody (LYP20) directed against a granule membrane glycoprotein (GMP-140/PADGEM).

S Parmentier, L McGregor, B Catimel, LL Leung, JL McGregor

Journal article  |  1991  |  Blood

Granule membrane protein (GMP-140), also known as platelet activation-dependent granule-external membrane (PAD-GEM) is an integral..

New families of adhesion molecules play a vital role in platelet functions.

S Parmentier, C Kaplan, B Catimel, JL McGregor

Journal article  |  1990  |  Immunology Today

Adhesion molecules play a crucial part in cell-matrix and in cell-cell interactions. These interactions, which are essential to th..

New families of adhesion molecules play a vital role in platelet functions

S Parmentier, C Kaplan, B Catimel, JL McGregor

Journal article  |  1990  |  Trends in Immunology

Aggregation to thrombin and collagen of platelets from a Glanzmann thrombasthenic patient lacking glycoproteins IIb and IIIa.

L McGregor, M Hanss, A Sayegh, JJ Calvette, MC Trzeciak, D Ville, B Catimel, JJ Viala, M Dechavanne, JL McGregor

Journal article  |  1989  |  Thrombosis and Haemostasis

The aim of this study was to investigate the platelets of a Glanzmann thrombasthenic patient, which in citrated PRP failed to resp..

Rapid purification and partial characterization of human platelet glycoprotein IIIb. Interaction with thrombospondin and its role in platelet aggregation.

JL McGregor, B Catimel, S Parmentier, P Clezardin, M Dechavanne, LL Leung

Journal article  |  1989  |  Journal of Biological Chemistry

Glycoprotein IIIb (also known as glycoprotein IV) is a major glycoprotein present on the surface of human platelets. Recent studie..

Identification of two distinct regions within the binding sites for fibrinogen and fibronectin on the IIb-IIIa human platelet membrane glycoprotein complex by monoclonal antibodies P2 and P4.

JL McGregor, L McGregor, AS Bauer, B Catimel, J Brochier, M Dechavanne, KJ Clemetson

Journal article  |  1986  |  European Journal of Biochemistry

The effect of two monoclonal antibodies P2 (LyP 2) or P4 (LyP 4), specific for the platelet membrane glycoprotein IIb/IIIa complex..