Eric Hanssen

The multi-faceted mechano-bactericidal mechanism of nanostructured surfaces

Elena P Ivanova, Denver P Linklater, Marco Werner, Vladimir A Baulin, XiuMei Xu, Nandi Vrancken, Sergey Rubanov, Eric Hanssen, Jason Wandiyanto, Vi Khanh Truong, Aaron Elbourne, Shane Maclaughlin, Saulius Juodkazis, Russell J Crawford

Journal article  |  2020  |  Proceedings of the National Academy of Sciences

The mechano-bactericidal activity of nanostructured surfaces has become the focus of intensive research toward the development of ..

Tailoring the structure of casein micelles through a multifactorial approach to manipulate rennet coagulation properties

F Lazzaro, A Bouchoux, J Raynes, R Williams, L Ong, E Hanssen, V Lechevalier, S Pezennec, HJ Cho, A Logan, S Gras, F Gaucheron

Journal article  |  2020  |  Food Hydrocolloids

The properties of casein micelles are known to be affected by modifications to the environment, such as variations in pH or the ad..

Ordered Mesoporous Metal-Phenolic Network Particles.

Zhixing Lin, Jiajing Zhou, Christina Cortez-Jugo, Yiyuan Han, Yutian Ma, Shuaijun Pan, Eric Hanssen, Joseph J Richardson, Frank Caruso

Journal article  |  2020  |  Journal of the American Chemical Society

Mesoporous metal-organic networks have attracted widespread interest owing to their potential applications in diverse fields inclu..

Automated segmentation of cardiomyocyte Z-disks from high-throughput scanning electron microscopy data.

Afshin Khadangi, Eric Hanssen, Vijay Rajagopal

Journal article  |  2019  |  BMC Medical Informatics and Decision Making

BACKGROUND: With the advent of new high-throughput electron microscopy techniques such as serial block-face scanning electron micr..

The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis

Stanley C Xie, Riley D Metcalfe, Eric Hanssen, Tuo Yang, David L Gillett, Andrew P Leis, Craig J Morton, Michael J Kuiper, Michael W Parker, Natalie J Spillman, Wilson Wong, Christopher Tsu, Lawrence R Dick, Michael DW Griffin, Leann Tilley

Journal article  |  2019  |  Nature Microbiology

The activity of the proteasome 20S catalytic core is regulated by protein complexes that bind to one or both ends. The PA28 regula..

Identification of Two Independent COL5A1 Variants in Dogs with Ehlers-Danlos Syndrome

Anina Bauer, John F Bateman, Shireen R Lamande, Eric Hanssen, Shannon GM Kirejczyk, Mark Yee, Ali Ramiche, Vidyha Jagannathan, Monika Welle, Tosso Leeb, Fiona L Bateman

Journal article  |  2019  |  Genes

The Ehlers-Danlos syndromes (EDS) are a heterogeneous group of heritable disorders affecting connective tissues. The mutations cau..

A novel target for splice-modulating therapies: a common pseudoexon-inducing mutation that causes a severe collagen VI-related muscular dystrophy

V Bolduc, A Foley, H Solomon Degefa, A Sarathy, S Donkervoort, Y Hu, H Zhou, B Cummings, M Lek, O Regev, C Jimenez-Mallebrera, V Allamand, A Ferlini, S Wilton, E Hanssen, S Lamande, D MacArthur, R Wagener, F Muntoni, C Bonnemann

Conference Proceedings  |  2019  |  Neuromuscular Disorders

Thermally coupled dark-anoxia incubation: A platform technology to induce auto-fermentation and thus cell-wall thinning in both nitrogen-replete and nitrogen-deplete Nannochloropsis slurries

Ronald Halim, David RA Hill, Eric Hanssen, Paul A Webley, Gregory JO Martin

Journal article  |  2019  |  Bioresource Technology

Nitrogen-deprived Nannochloropsis cells invested their fixed carbon into the accumulation of triacylglycerol and cell wall cellulo..

A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites

M Fleur Sernee, Julie E Ralton, Tracy L Nero, Lukasz F Sobala, Joachim Kloehn, Marcel A Vieira-Lara, Simon A Cobbold, Lauren Stanton, Douglas EV Pires, Eric Hanssen, Alexandra Males, Tom Ward, Laurence M Bastidas, Phillip L van der Peet, Michael W Parker, David B Ascher, Spencer J Williams, Gideon J Davies, Malcolm J McConville

Journal article  |  2019  |  Cell Host & Microbe

Display of malaria transmission-blocking antigens on chimeric duck hepatitis B virus-derived virus-like particles produced in Hansenula polymorpha

David Wetzel, Jo-Anne Chan, Manfred Suckow, Andreas Barbian, Michael Weniger, Volker Jenzelewski, Linda Reiling, Jack S Richards, David A Anderson, Betty Kouskousis, Catherine Palmer, Eric Hanssen, Gerhard Schembecker, Juliane Merz, James G Beeson, Michael Piontek

Journal article  |  2019  |  PLOS ONE

CRYO-EM OF THE MALARIA PARASITE PA28/20S PROTEASOME COMPLEX REVEALS AN UNUSUAL ACTIVATION MECHANISM WITH IMPLICATIONS FOR ARTEMISININ SENSITIVITY

Stanley Xie, Michael Griffin, Riley Metcalfe, Eric Hanssen, Tuo Yang, David Gilley, Andrew Leis, Craig Morton, Michael Kuiper, Michael Parker, Natalie Spillman, Wilson Wong, Christopher Tsu, Lawrence Dick, Leann Tilley

Conference Proceedings  |  2019  |  PROTEIN SCIENCE

Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking

Kit Kennedy, Simon A Cobbold, Eric Hanssen, Jakob Birnbaum, Natalie J Spillman, Emma McHugh, Hannah Brown, Leann Tilley, Tobias Spielmann, Malcolm J McConville, Stuart A Ralph

Journal article  |  2019  |  PLOS BIOLOGY

Apicomplexan parasites possess a plastid organelle called the apicoplast. Inhibitors that selectively target apicoplast housekeepi..

Towards sustainable microalgal biomass processing: anaerobic induction of autolytic cell-wall self-ingestion in lipid-rich Nannochloropsis slurries

Ronald Halim, David RA Hill, Eric Hanssen, Paul A Webley, Susan Blackburn, Arthur R Grossman, Clemens Posten, Gregory JO Martin

Journal article  |  2019  |  Green Chemistry

Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death

Amy A Baxter, Thanh Kha Phan, Eric Hanssen, Michael Liem, Mark D Hulett, Suresh Mathivanan, Ivan KH Poon

Journal article  |  2019  |  Scientific Reports

Multimodal analysis of Plasmodium knowlesi-infected erythrocytes reveals large invaginations, swelling of the host cell, and rheological defects

Boyin Liu, Adam J Blanch, Arman Namvar, Olivia Carmo, Snigdha Tiash, Dean Andrew, Eric Hanssen, Vijay Rajagopal, Matthew WA Dixon, Leann Tilley

Journal article  |  2019  |  CELLULAR MICROBIOLOGY

A Common Deep Intronic Mutation Causing Collagen VI-Related Muscular Dystrophy: Validation of Splice-Modulating Approaches In Vitro and Development of a Mouse Model

Veronique Bolduc, A Reghan Foley, Herimela Solomon-Degefa, Apurva Sarathy, Sandra Donkervoort, Ying Hu, Grace S Chen, Matthew Nalls, Haiyan Zhou, Sara Aguti, Beryl B Cummings, Monkol Lek, Taru Tukiainen, Jamie L Marshall, Oded Regev, Dina Marek-Yagel, Anna Sarkozy, Russell J Butterfield, Cristina Jou, Cecilia Jimenez-Mallebrera, et al.

Conference Proceedings  |  2019  |  MOLECULAR THERAPY

A recurrent COL6A1 pseudoexon insertion causes muscular dystrophy and is effectively targeted by splice-correction therapies

Veronique Bolduc, A Reghan Foley, Herimela Solomon-Degefa, Apurva Sarathy, Sandra Donkervoort, Ying Hu, Grace S Chen, Katherine Sizov, Matthew Nalls, Haiyan Zhou, Sara Aguti, Beryl B Cummings, Monkol Lek, Taru Tukiainen, Jamie L Marshall, Oded Regev, Dina Marek-Yagel, Anna Sarkozy, Russell J Butterfield, Cristina Jou, et al.

Journal article  |  2019  |  JCI Insight

Interaction of Giant Unilamellar Vesicles with the Surface Nanostructures on Dragonfly Wings

Samuel Cheeseman, Khanh Truong Vi, Vivien Walter, Fabrice Thalmann, Carlos M Marques, Eric Hanssen, Jitraporn Vongsvivut, Mark J Tobin, Vladimir A Baulin, Saulius Juodkazis, Shane Maclaughlin, Gary Bryant, Russell J Crawford, Elena P Ivanova

Journal article  |  2019  |  Langmuir

In Situ Monitoring of Bacteria under Antimicrobial Stress Using P-31 Solid-State NMR

Sarah A Overall, Shiying Zhu, Eric Hanssen, Frances Separovic, Marc-Antoine Sani

Journal article  |  2019  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture

Shouryadipta Ghosh, Kenneth Tran, Lea MD Delbridge, Anthony JR Hickey, Eric Hanssen, Edmund J Crampin, Vijay Rajagopal

Journal article  |  2018  |  PLOS COMPUTATIONAL BIOLOGY

Gel-Mediated Electrospray Assembly of Silica Supraparticles for Sustained Drug Delivery

Yutian Ma, Mattias Bjoernmalm, Andrew K Wise, Christina Cortez-Jugo, Eve Revalor, Yi Ju, Orlagh M Feeney, Rachael T Richardson, Eric Hanssen, Robert K Shepherd, Christopher JH Porter, Frank Caruso

Journal article  |  2018  |  ACS APPLIED MATERIALS & INTERFACES

High Aspect Ratio Nanostructures Kill Bacteria via Storage and Release of Mechanical Energy

Denver P Linklater, Michael De Volder, Vladimir A Baulin, Marco Werner, Sarah Jessl, Mehdi Golozar, Laura Maggini, Sergey Rubanov, Eric Hanssen, Saulius Juodkazis, Elena P Ivanova

Journal article  |  2018  |  ACS Nano

An automated workflow for segmenting single adult cardiac cells from large-volume serial block-face scanning electron microscopy data

Akter Hussain, Shouryadipta Ghosh, Siavash Beikoghli Kalkhoran, Derek J Hausenloy, Eric Hanssen, Vijay Rajagopal

Journal article  |  2018  |  Journal of Structural Biology

Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture

Shouryadipta Ghosh, Kenneth Tran, Lea Delbridge, Anthony Hickey, Eric Hanssen, Edmund Crampin, Vijay Rajagopal

Journal article  |  2018

Abstract Recent electron microscopy data have revealed that cardiac mitochondria are not arranged in crystalline columns, but are ..

Biochemical transformation of calciprotein particles in uraemia

Edward R Smith, Tim D Hewitson, Eric Hanssen, Stephen G Holt

Journal article  |  2018  |  Bone

Creating a Structurally Realistic Finite Element Geometric Model of a Cardiomyocyte to Study the Role of Cellular Architecture in Cardiomyocyte Systems Biology

Vijay Rajagopal, Gregory Bass, Shouryadipta Ghosh, Hilary Hunt, Cameron Walkers, Eric Hanssen, Edmund Crampin, Christian Soeller

Journal article  |  2018  |  Journal of Visualized Experiments

Sequential Membrane Rupture and Vesiculation during Plasmodium berghei Gametocyte Egress from the Red Blood Cell

Maria Andreadaki, Eric Hanssen, Elena Deligianni, Cyrille Claudet, Kai Wengelnik, Vanessa Mollard, Geoffrey I McFadden, Manouk Abkarian, Catherine Braun-Breton, Inga Siden-Kiamos

Journal article  |  2018  |  Scientific Reports

The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity

Prajakta Gosavi, Fiona J Houghton, Paul J McMillan, Eric Hanssen, Paul A Gleeson

Journal article  |  2018  |  Journal of Cell Science

Biologically active constituents of the secretome of human W8B2( ) cardiac stem cells

Shuai Nie, Xin Wang, Priyadharshini Sivakumaran, Mark MW Chong, Xin Liu, Tara Karnezis, Nadeeka Bandara, Kaloyan Takov, Cameron J Nowell, Stephen Wilcox, Mitch Shambrook, Andrew F Hill, Nicole C Harris, Andrew E Newcomb, Padraig Strappe, Ramin Shayan, Damian Hernandez, Jordan Clarke, Eric Hanssen, Sean M Davidson, et al.

Journal article  |  2018  |  SCIENTIFIC REPORTS

An Automated Workflow for Segmenting Single Adult Cardiac Cells from Large-Volume Serial Block-Face Scanning Electron Microscopy Data

Akter Hussain, Shouryadipta Ghosh, Siavash Beikoghli Kalkhoran, Derek Hausenloy, Eric Hanssen, Vijay Rajagopal

Journal article  |  2018

ABSTRACT This paper presents a new algorithm to automatically segment the myofibrils, mitochondria and nuclei within single adult ..

Cellular Imaging

Book  |  2018

This book highlights important techniques for cellular imaging and covers the basics and applications of electron tomography and r..

Clickable Cubosomes for Antibody-Free Drug Targeting and Imaging Applications

Nicolas Alcaraz, Qingtao Liu, Eric Hansen, Angus Johnston, Ben J Boyd

Journal article  |  2018  |  Bioconjugate Chemistry

Automated framework to reconstruct 3D model of cardiac Z-disk: an image processing approach

Eric Hanssen, V Rajagopal, Afshin Khadankishandi

Conference Proceedings  |  2018  |  PROCEEDINGS 2018 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE (BIBM)

The Z-disk or Z-line is located at the lateral borders of sarcomere, the fundamental unit of striated muscle. They provide mechani..

Biologically active composition of human W8B2( ) cardiac stem cell secretome

P Sivakumaran, S Nie, X Wang, T Karnezis, N Bandara, C Nowell, S Wilcox, AF Hill, M Shambrook, NC Harris, AE Newcomb, P Strappe, R Shayan, D Hernandez, J Clarke, GJ Dusting, K Takov, S Davidson, E Hanssen, A Pebay, et al.

Conference Proceedings  |  2017  |  HUMAN GENE THERAPY

Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development

Molly Parkyn Schneider, Boyin Liu, Philipp Glock, Annika Suttie, Emma McHugh, Dean Andrew, Steven Batinovic, Nicholas Williamson, Eric Hanssen, Paul McMillan, Marion Hliscs, Leann Tilley, Matthew WA Dixon

Journal article  |  2017  |  PLOS PATHOGENS

The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

Sarah C Charnaud, Matthew WA Dixon, Catherine Q Nie, Lia Chappell, Paul R Sanders, Thomas Nebl, Eric Hanssen, Matthew Berriman, Jo-Anne Chan, Adam J Blanch, James G Beeson, Julian C Rayner, Jude M Przyborski, Leann Tilley, Brendan S Crabb, Paul R Gilson

Journal article  |  2017  |  PLOS ONE

A Semi-Automated Workflow for Segmenting Contents of Single Cardiac Cells from Serial-Block-Face Scanning Electron Microscopy Data

Akter Hussain, Eric Hanssen, Vijay Rajagopal

Conference Proceedings  |  2017  |  Microscopy and Microanalysis

Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis

Wilson Wong, Xiao-Chen Bai, Brad E Sleebs, Tony Triglia, Alan Brown, Jennifer K Thompson, Katherine E Jackson, Eric Hanssen, Danushka S Marapana, Israel S Fernandez, Stuart A Ralph, Alan F Cowman, Sjors HW Scheres, Jake Baum

Journal article  |  2017  |  Nature Microbiology

A nanomechanical study of the effects of colistin on the Klebsiella pneumoniae AJ218 capsule

Anna Mularski, Jonathan Wilksch, Eric Hanssen, Jian Li, Takehiro Tomita, Sacha James Pidot, Tim Stinear, Frances Separovic, Dick Strugnell

Journal article  |  2017  |  EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

A Dominant-Negative COL6A1 Pseudoexon Insertion Is Skippable Using Splice-Modulating Oligonucleotides

Veronique Bolduc, A Reghan Foley, Sandra Donkervoort, Ying Hu, Beryl B Cummings, Monkol Lek, Apurva Sarathy, Katherine Sizov, Herimela Solomon Degefa, Raimund Wagener, Grant W Hennig, Eric Hanssen, Shireen R Lamande, Francesco Muntoni, Steve D Wilton, Daniel G MacArthur, Carsten G Bonnemann

Conference Proceedings  |  2017  |  MOLECULAR THERAPY

Changes in mitochondrial morphology and organization can enhance energy supply from mitochondrial oxidative phosphorylation in diabetic cardiomyopathy

Jan Jarosz, Shouryadipta Ghosh, Lea MD Delbridge, Amorita Petzer, Anthony JR Hickey, Edmund J Crampin, Eric Hanssen, Vijay Rajagopal

Journal article  |  2017  |  American Journal of Physiology-Cell Physiology

A Computational Study of the Role of Mitochondrial Organization on Cardiac Bioenergetics

Shouryadipta Ghosh, Edmund J Crampin, Eric Hanssen, Vijay Rajagopal

Conference Proceedings  |  2017  |  2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite

Danielle I Stanisic, John Gerrard, James Fink, Paul M Griffin, Xue Q Liu, Lana Sundac, Silvana Sekuloski, Ingrid B Rodriguez, Jolien Pingnet, Yuedong Yang, Yaoqi Zhou, Katharine R Trenholme, Claire YT Wang, Hazel Hackett, Jo-Anne A Chan, Christine Langer, Eric Hanssen, Stephen L Hoffman, James G Beeson, James S McCarthy, et al.

Journal article  |  2016  |  Infection and Immunity

Structural Insights into the PorK and PorN Components of the Porphyromonas gingivalis Type IX Secretion System

Dhana G Gorasia, Paul D Veith, Eric G Hanssen, Michelle D Glew, Keiko Sato, Hideharu Yukitake, Koji Nakayama, Eric C Reynolds

Journal article  |  2016  |  PLOS PATHOGENS

Atomic force microscopy of bacteria reveals the mechanobiology of pore forming peptide action

Anna Mularski, Jonathan J Wilksch, Eric Hanssen, Richard A Strugnell, Frances Separovic

Journal article  |  2016  |  BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Immobilized Particle Imaging for Quantification of Nano- and Microparticles

Jiwei Cui, Benjamin Hibbs, Sylvia T Gunawan, Julia A Braunger, Xi Chen, Joseph J Richardson, Eric Hanssen, Frank Caruso

Journal article  |  2016  |  LANGMUIR

Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells

Shashi K Gopal, David W Greening, Eric G Hanssen, Hong-Jian Zhu, Richard J Simpson, Rommel A Mathias

Journal article  |  2016  |  Oncotarget

Inhibition of hIAPP Amyloid Aggregation and Pancreatic beta-Cell Toxicity by OH-Terminated PAMAM Dendrimer

Esteban N Gurzov, Bo Wang, Emily H Pilkington, Pengyu Chen, Aleksandr Kakinen, William J Stanley, Sara A Litwak, Eric G Hanssen, Thomas P Davis, Feng Ding, Pu Chun Ke

Journal article  |  2016  |  Small

Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins

Stanley C Xie, Con Dogovski, Eric Hanssen, Francis Chiu, Tuo Yang, Maria P Crespo, Che Stafford, Steven Batinovic, Silvia Teguh, Susan Charman, Nectarios Klonis, Leann Tilley

Journal article  |  2016  |  Journal of Cell Science

A repeat sequence domain of the ring-exported protein-1 of Plasmodium falciparum controls export machinery architecture and virulence protein trafficking

Emma McHugh, Steven Batinovic, Eric Hanssen, Paul J McMillan, Shannon Kenny, Michael DW Griffin, Simon Crawford, Katharine R Trenholme, Donald L Gardiner, Matthew WA Dixon, Leann Tilley

Journal article  |  2015  |  Molecular Microbiology

Thermorudis pharmacophila sp nov., a novel member of the class Thermomicrobia isolated from geothermal soil, and emended descriptions of Thermomicrobium roseum, Thermomicrobium carboxidum, Thermorudis peleae and Sphaerobacter thermophilus

Karen M Houghton, Xochitl C Morgan, Kirill Lagutin, Andrew D MacKenzie, Mikhail Vyssotskii, Kevin A Mitchell, Ian R McDonald, Hugh W Morgan, Jean F Power, John W Moreau, Eric Hanssen, Matthew B Stott

Journal article  |  2015  |  INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Interactions between Plasmodium falciparum skeleton-binding protein 1 and the membrane skeleton of malaria-infected red blood cells

Lev M Kats, Nicholas I Proellocks, Donna W Buckingham, Lionel Blanc, John Hale, Xinhua Guo, Xinhong Pei, Susann Herrmann, Eric G Hanssen, Ross L Coppel, Narla Mohandas, Xiuli An, Brian M Cooke

Journal article  |  2015  |  Biochimica et Biophysica Acta (BBA) - Biomembranes

Limisphaera ngatamarikiensis gen. nov., sp nov., a thermophilic, pink-pigmented coccus isolated from subaqueous mud of a geothermal hotspring

Heike Anders, Jean F Power, Andrew D MacKenzie, Kirill Lagutin, Mikhail Vyssotski, Eric Hanssen, John W Moreau, Matthew B Stott

Journal article  |  2015  |  International Journal of Systematic and Evolutionary Microbiology

Distinct properties of the egress-related osmiophilic bodies in male and female gametocytes of the rodent malaria parasite Plasmodium berghei

Anna Olivieri, Lucia Bertuccini, Elena Deligianni, Blandine Franke-Fayard, Chiara Curra, Inga Siden-Kiamos, Eric Hanssen, Felicia Grasso, Fabiana Superti, Tomasino Pace, Federica Fratini, Chris J Janse, Marta Ponzi

Journal article  |  2015  |  Cellular Microbiology

Aberrant Mitochondria in a Bethlem Myopathy Patient with a Homozygous Amino Acid Substitution That Destabilizes the Collagen VI alpha 2(VI) Chain

Laura K Zamurs, Miguel A Idoate, Eric Hanssen, Asier Gomez-Ibanez, Pau Pastor, Shireen R Lamande

Journal article  |  2015  |  Journal of Biological Chemistry

A molecular nematic liquid crystalline material for high-performance organic photovoltaics

Kuan Sun, Zeyun Xiao, Shirong Lu, Wojciech Zajaczkowski, Wojciech Pisula, Eric Hanssen, Jonathan M White, Rachel M Williamson, Jegadesan Subbiah, Jianyong Ouyang, Andrew B Holmes, Wallace WH Wong, David J Jones

Journal article  |  2015  |  NATURE COMMUNICATIONS

Export of virulence proteins by malaria-infected erythrocytes involves remodeling of host actin cytoskeleton

Melanie Rug, Marek Cyrklaff, Antti Mikkonen, Leandro Lemgruber, Simone Kuelzer, Cecilia P Sanchez, Jennifer Thompson, Eric Hanssen, Matthew O'Neill, Christine Langer, Michael Lanzer, Friedrich Frischknecht, Alexander G Maier, Alan F Cowman

Journal article  |  2014  |  Blood

A lysine-rich membrane-associated PHISTb protein involved in alteration of the cytoadhesive properties of Plasmodium falciparum-infected red blood cells

Nicholas I Proellocks, Susann Herrmann, Donna W Buckingham, Eric Hanssen, Emma K Hodges, Brendan Elsworth, Belinda J Morahan, Ross L Coppel, Brian M Cooke

Journal article  |  2014  |  The FASEB Journal

Membrane-Wrapping Contributions to Malaria Parasite Invasion of the Human Erythrocyte

Sabyasachi Dasgupta, Thorsten Auth, Nir S Gov, Timothy J Satchwell, Eric Hanssen, Elizabeth S Zuccala, David T Riglar, Ashley M Toye, Timo Betz, Jake Baum, Gerhard Gompper

Journal article  |  2014  |  Biophysical Journal

Morphology Change and Improved Efficiency in Organic Photovoltaics via Hexa-peri-hexabenzocoronene Templates

Henk H Dam, Kuan Sun, Eric Hanssen, Jonathan M White, Tomasz Marszalek, Wojciech Pisula, Jens Czolk, Jens Ludwig, Alexander Colsmann, Marina Pfaff, Dagmar Gerthsen, Wallace WH Wong, David J Jones

Journal article  |  2014  |  ACS APPLIED MATERIALS & INTERFACES

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine

Wilson Wong, Xiao-chen Bai, Alan Brown, Israel S Fernandez, Eric Hanssen, Melanie Condron, Yan Hong Tan, Jake Baum, Sjors HW Scheres

Journal article  |  2014  |  ELIFE

Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility

Andrey Kan, Yan-Hong Tan, Fiona Angrisano, Eric Hanssen, Kelly L Rogers, Lachlan Whitehead, Vanessa P Mollard, Anton Cozijnsen, Michael J Delves, Simon Crawford, Robert E Sinden, Geoffrey I McFadden, Christopher Leckie, James Bailey, Jake Baum

Journal article  |  2014  |  CELLULAR MICROBIOLOGY

The Apical Complex Provides a Regulated Gateway for Secretion of Invasion Factors in Toxoplasma

Nicholas J Katris, Giel G van Dooren, Paul J McMillan, Eric Hanssen, Leann Tilley, Ross F Waller

Journal article  |  2014  |  PLOS PATHOGENS

Local regularization of tilt projections reduces artifacts in electron tomography

Mauro Majorca, Coralie Millet, Eric Hanssen, Brian Abbey, Edmund Kazmierczak, Leann Tilley

Journal article  |  2014  |  Journal of structural biology

Thermoflavifilum aggregans gen. nov., sp nov., a thermophilic and slightly halophilic filamentous bacterium from the phylum Bacteroidetes

Heike Anders, Peter F Dunfield, Kirill Lagutin, Karen M Houghton, Jean F Power, Andrew D MacKenzie, Mikhail Vyssotski, Jason LJ Ryan, Eric G Hanssen, John W Moreau, Matthew B Stott

Journal article  |  2014  |  International Journal of Systematic and Evolutionary Microbiology

A Mechanism for Actin Filament Severing by Malaria Parasite Actin Depolymerizing Factor 1 via a Low Affinity Binding Interface

Wilson Wong, Andrew I Webb, Maya A Olshina, Giuseppe Infusini, Yan Hong Tan, Eric Hanssen, Bruno Catimel, Cristian Suarez, Melanie Condron, Fiona Angrisano, Thomas Neb, David R Kovar, Jake Baum

Journal article  |  2014  |  Journal of Biological Chemistry

The role of solvent vapor annealing in highly efficient air-processed small molecule solar cells

Kuan Sun, Zeyun Xiao, Eric Hanssen, Michael FG Klein, Henk H Dam, Marina Pfaff, Dagmar Gerthsen, Wallace WH Wong, David J Jones

Journal article  |  2014  |  JOURNAL OF MATERIALS CHEMISTRY A

Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion

Eric Hanssen, Chaitali Dekiwadia, David T Riglar, Melanie Rug, Leandro Lemgruber, Alan F Cowman, Marek Cyrklaff, Mikhail Kudryashev, Friedrich Frischknecht, Jake Baum, Stuart A Ralph

Journal article  |  2013  |  CELLULAR MICROBIOLOGY

Spatial and temporal mapping of the PfEMP1 export pathway in Plasmodium falciparum

Paul J McMillan, Coralie Millet, Steven Batinovic, Mauro Maiorca, Eric Hanssen, Shannon Kenny, Rebecca A Muhle, Martin Melcher, David A Fidock, Joseph D Smith, Matthew WA Dixon, Leann Tilley

Journal article  |  2013  |  CELLULAR MICROBIOLOGY

The Exported Protein PbCP1 Localises to Cleft-Like Structures in the Rodent Malaria Parasite Plasmodium berghei

Silvia Haase, Eric Hanssen, Kathryn Matthews, Ming Kalanon, Tania F de Koning-Ward

Journal article  |  2013  |  PLoS One

Fetuin-A-Containing Calciprotein Particles Reduce Mineral Stress in the Macrophage

Edward R Smith, Eric Hanssen, Lawrence P McMahon, Stephen G Holt

Journal article  |  2013  |  PLoS One

Spatial association with PTEX complexes defines regions for effector export into Plasmodium falciparum-infected erythrocytes

David T Riglar, Kelly L Rogers, Eric Hanssen, Lynne Turnbull, Hayley E Bullen, Sarah C Charnaud, Jude Przyborski, Paul R Gilson, Cynthia B Whitchurch, Brendan S Crabb, Jake Baum, Alan F Cowman

Journal article  |  2013  |  Nature Communications

Shape-shifting gametocytes: how and why does P-falciparum go banana-shaped?

Matthew WA Dixon, Megan K Dearnley, Eric Hanssen, Tim Gilberger, Leann Tilley

Journal article  |  2012  |  Trends in Parasitology

Prion-infected cells regulate the release of exosomes with distinct ultrastructural features

Bradley M Coleman, Eric Hanssen, Victoria A Lawson, Andrew F Hill

Journal article  |  2012  |  FASEB JOURNAL

Improving the quality of electron tomography image volumes using pre-reconstruction filtering

Mauro Maiorca, Eric Hanssen, Edmund Kazmierczak, Bohumil Maco, Misha Kudryashev, Richard Hall, Harry Quiney, Leann Tilley

Journal article  |  2012  |  Journal of structural biology

A 95 kDa protein of Plasmodium vivax and P. cynomolgi visualized by three-dimensional tomography in the caveola-vesicle complexes (Schuffner's dots) of infected erythrocytes is a member of the PHIST family

Sheila Akinyi, Eric Hanssen, Esmeralda VS Meyer, Jianlin Jiang, Cindy C Korir, Balwan Singh, Stacey Lapp, John W Barnwell, Leann Tilley, Mary R Galinski

Journal article  |  2012  |  Molecular Microbiology

Origin, composition, organization and function of the inner membrane complex of Plasmodium falciparum gametocytes

Megan K Dearnley, Jeffrey A Yeoman, Eric Hanssen, Shannon Kenny, Lynne Turnbull, Cynthia B Whitchurch, Leann Tilley, Matthew WA Dixon

Journal article  |  2012  |  Journal of Cell Science

Soft X-ray microscopy analysis of cell volume and hemoglobin content in erythrocytes infected with asexual and sexual stages of Plasmodium falciparum

Eric Hanssen, Christian Knoechel, Megan Dearnley, Matthew WA Dixon, Mark Le Gros, Carolyn Larabell, Leann Tilley

Journal article  |  2012  |  Journal of structural biology

Soft X-ray microscopy analysis of cell volume and hemoglobin content in erythrocytes infected with asexual and sexual stages of Plasmodium falciparum

E Hanssen, C Knoechel, MK Dearnley, MW Dixon, M Le Gros, C Larabell, L Tilley

Journal article  |  2012  |  Journal of structural biology

Super-resolution optical imaging of malaria parasites

L Tilley, P McMillan, M Dixon, E Hanssen, J Yeoman, C Whitchurch, N Klonis

Conference Proceedings  |  2011  |  Optics InfoBase Conference Papers

Super-resolution optical imaging of malaria parasites

L Tillev, P McMillan, M Dixon, E Hanssen, J Yeoman, C Whitchurch, N Klonis

Conference Proceedings  |  2011  |  2011 International Quantum Electronics Conference (IQEC) and Conference on Lasers and Electro-Optics (CLEO) Pacific Rim incorporating the Australasian Conference on Optics, Lasers and Spectroscopy and the Australian Conference on Optical Fibre Technology

Genetic ablation of a Maurer's cleft protein prevents assembly of the Plasmodium falciparum virulence complex

Matthew WA Dixon, Shannon Kenny, Paul J McMillan, Eric Hanssen, Katharine R Trenholme, Donald L Gardiner, Leann Tilley

Journal article  |  2011  |  Molecular Microbiology

Relevant Assay to Study the Adhesion of Plasmodium falciparum-Infected Erythrocytes to the Placental Epithelium

Philippe Boeuf, Wina Hasang, Eric Hanssen, Jocelyn D Glazier, Stephen J Rogerson

Journal article  |  2011  |  PLOS ONE

Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1

Wilson Wong, Colleen T Skau, Danushka S Marapana, Eric Hanssen, Nicole L Taylor, David T Riglar, Elizabeth S Zuccala, Fiona Angrisano, Heather Lewis, Bruno Catimel, Oliver B Clarke, Nadia J Kershaw, Matthew A Perugini, David R Kovar, Jacqueline M Gulbis, Jake Baum

Journal article  |  2011  |  Proceedings of the National Academy of Sciences of the United States of America

Tracking Glideosome-Associated Protein 50 Reveals the Development and Organization of the Inner Membrane Complex of Plasmodium falciparum

Jeffrey A Yeoman, Eric Hanssen, Alexander G Maier, Nectarios Klonis, Bohumil Maco, Jake Baum, Lynne Turnbull, Cynthia B Whitchurch, Matthew WA Dixon, Leann Tilley

Journal article  |  2011  |  Eukaryotic Cell

Cryo transmission X-ray imaging of the malaria parasite, P. falciparum

Eric Hanssen, Christian Knoechel, Nectarios Klonis, Nurhidanatasha Abu-Bakar, Samantha Deed, Mark LeGros, Carolyn Larabell, Leann Tilley

Journal article  |  2011  |  Journal of structural biology

MAHRP2, an exported protein of Plasmodium falciparum, is an essential component of Maurer's cleft tethers

Esther Pachlatko, Sebastian Rusch, Anouk Mueller, Andrew Hemphill, Leann Tilley, Eric Hanssen, Hans-Peter Beck

Journal article  |  2010  |  Molecular Microbiology

Cellular architecture of Plasmodium falciparum-infected erythrocytes

Eric Hanssen, Paul J McMillan, Leann Tilley

Journal article  |  2010  |  International Journal for Parasitology

Hematin-Hematin Self-Association States Involved in the Formation and Reactivity of the Malaria Parasite Pigment, Hemozoin

Nectarios Klonis, Ruben Dilanian, Eric Hanssen, Connie Darmanin, Victor Streltsov, Samantha Deed, Harry Quiney, Leann Tilley

Journal article  |  2010  |  Biochemistry

Digestive-vacuole genesis and endocytic processes in the early intraerythrocytic stages of Plasmodium falciparum

Nurhidanatasha Abu Bakar, Nectarios Klonis, Eric Hanssen, Cherrine Chan, Leann Tilley

Journal article  |  2010  |  Journal of Cell Science

Whole cell imaging reveals novel modular features of the exomembrane system of the malaria parasite, Plasmodium falciparum

Eric Hanssen, Peter Carlton, Samantha Deed, Nectarios Klonis, John Sedat, Joe DeRisi, Leann Tilley

Journal article  |  2010  |  International Journal for Parasitology

Ultrastructure of the Asexual Blood Stages of Plasmodium falciparum

Eric Hanssen, Kenneth N Goldie, Leann Tilley

Book Chapter  |  2010  |  Methods in Cell Biology

Whole cell imaging of Plasmodium falciparum blood stages

Eric Hanssen, Christian Knoechel, Peter Carlton, John Sedat, Carolyn Larabell, Leann Tilley

Journal article  |  2009  |  Microscopy and Microanalysis

Characterisation of PfRON6, a Plasmodium falciparum rhoptry neck protein with a novel cysteine-rich domain

Nicholas I Proellocks, Lev M Kats, David A Sheffield, Eric Harissen, Casilda G Black, Karena L Waller, Ross L Coppel

Journal article  |  2009  |  International Journal for Parasitology

Functional alteration of red blood cells by a megadalton protein of Plasmodium falciparum

Fiona K Glenister, Kate M Fernandez, Lev M Kats, Eric Hanssen, Narla Mohandas, Ross L Coppel, Brian M Cooke

Journal article  |  2009  |  Blood

High-resolution X-ray imaging of Plasmodium falciparum-infected red blood cells

Garth J Williams, Eric Hanssen, Andrew G Peele, Mark A Pfeifer, Jesse Clark, Brian Abbey, Guido Cadenazzi, Martin D de Jonge, Stefan Vogt, Leann Tilley, Keith A Nugent

Journal article  |  2008  |  Cytometry Part A

Targeted mutagenesis of the ring-exported protein-1 of Plasmodium falciparum disrupts the architecture of Maurer's cleft organelles

Eric Hanssen, Paula Hawthorne, Matthew WA Dixon, Katharine R Trenholme, Paul J McMillan, Tobias Spielmann, Donald L Gardiner, Leann Tilley

Journal article  |  2008  |  Molecular Microbiology

The Maurer's cleft protein MAHRP1 is essential for trafficking of PfEMP1 to the surface of Plasmodium falciparum-infected erythrocytes

Cornelia Spycher, Melanie Rug, Esther Pachlatko, Eric Hanssen, David Ferguson, Alan F Cowman, Leann Tilley, Hans-Peter Beck

Journal article  |  2008  |  Molecular Microbiology

Quantitative phase measurement in coherent diffraction imaging

JN Clark, GJ Williams, HM Quiney, L Whitehead, MD de Jonge, E Hanssen, M Altissimo, KA Nugent, AG Peele

Journal article  |  2008  |  Optics Express

Electron tomography of the Maurer's cleft organelles of Plasmodium falciparum-infected erythrocytes reveals novel structural features

Eric Hanssen, Rachid Sougrat, Sarah Frankland, Samantha Deed, Nectarios Klonis, Jennifer Lippincott-Schwartzand, Leann Tilley

Journal article  |  2008  |  Molecular Microbiology

The twists and turns of Maurer's cleft trafficking in P-Falciparum-infected erythrocytes

Leann Tilley, Rachid Sougrat, Trevor Lithgow, Eric Hanssen

Journal article  |  2008  |  Traffic

A 3D view of the host cell compartment in P-falciparum-infected erythrocytes

L Tilley, E Hanssen

Journal article  |  2008  |  Transfusion Clinique et Biologique

The Maurer's cleft enigma.

Eric Hanssen, Rachid Sougrat, Sarah Frankland, Sam Deed, Leann Tilley

Conference Proceedings  |  2008  |  INTERNATIONAL JOURNAL FOR PARASITOLOGY

Artemisinin and a series of novel endoperoxide Antimalarials exert early effects on digestive vacuole morphology

Maria del Pilar Crespo, Thomas D Avery, Eric Hanssen, Emma Fox, Tony V Robinson, Peter Valente, Dennis K Taylor, Leann Tilley

Journal article  |  2008  |  Antimicrobial Agents and Chemotherapy

The Maurer's cleft protein MAHRP1 is essential for trafficking of PfEMP1 to the surface of Plasmodium falciparum-infected erythrocytes

C Spycher, M Rug, E Pachlatko, E Hanssen, D Ferguson, AF Cowman, L Tilley, HP Beck

Journal article  |  2008  |  Molecular Microbiology

Chelation of zinc inhibits growth of P-falciparum but antagonises the activity of artemisinin.

Nurhidanatasha Abu Bakar, Maria Del Pilar Crespo, Samantha Deed, Eric Hanssen, Garth Williams, Stefan Voght, Leann Tilley

Conference Proceedings  |  2008  |  INTERNATIONAL JOURNAL FOR PARASITOLOGY

Arternisinin and novel endoperoxides induce early effects on digestive vacuole integrity in Plasmodium falciparum.

Maria Del Pilar Crespo, Thomas Avery, Eric Hanssen, Dennis Taylor, Leann Tilley

Conference Proceedings  |  2008  |  INTERNATIONAL JOURNAL FOR PARASITOLOGY

The 'ins and outs' of trafficking in P-falciparum infected erythrocytes.

Leann Tilley, Eric Hanssen, Kath Jackson, Sarah Frankland, Nick Klonis, Alex Maier, Rachid Sougrat, Alan Cowman, Jennifer Lippincott-Schwartz

Conference Proceedings  |  2008  |  INTERNATIONAL JOURNAL FOR PARASITOLOGY

Characterizing the endocytic pathways in Plasmodium falciparuin-infected red blood cells.

Katherine Jackson, Olivia Tan, Jeffrey Yeoman, Nectarios Klonis, Eric Hanssen, Michael Klemba, Alexander G Maier, Alan F Cowman, Leann Tilley

Conference Proceedings  |  2008  |  INTERNATIONAL JOURNAL FOR PARASITOLOGY

Antimalarial activity and mechanism of action of artemisinin antimalarials: Is the digestive vacuole (DV) the primary target?

Maria del Pillar Crespo Ortiz, Thomas Avery, Eric Hanssen, Dennis Taylor, Leann Tilley

Conference Proceedings  |  2007  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein

Rena Hirani, Eric Hanssen, Mark A Gibson

Journal article  |  2007  |  Matrix Biol

Selective permeabilization of the host cell membrane of Plasmodium falciparum-infected red blood cells with streptolysin O and equinatoxin II

Katherine E Jackson, Tobias Spielmann, Eric Hanssen, Akinola Adisa, Frances Separovic, Matthew WA Dixon, Katharine R Trenholme, Paula L Hawthorne, Don L Gardiner, Tim Gilberger, Leann Tilley

Journal article  |  2007  |  Biochemical Journal

X-ray ultramicroscopy using integrated sample cells

Dachao Gao, Stephen W Wilkins, David J Parry, Tim E Gureyev, Peter R Miller

Journal article  |  2006  |  Opt Express

beta ig-h3 interacts directly with biglycan and decorin, promotes collagen VI aggregation, and participates in ternary complexing with these macromolecules

B Reinboth, J Thomas, E Hanssen, MA Gibson

Journal article  |  2006  |  J Biol Chem

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils

E Hanssen, FH Hew, E Moore, MA Gibson

Journal article  |  2004  |  J Biol Chem

Covalent and non-covalent interactions of beta ig-h3 with collagen VI - beta ig-h3 is covalently attached to the amino-terminal region of collagen VI in tissue microfibrils

E Hanssen, B Reinboth, MA Gibson

Journal article  |  2003  |  J Biol Chem

Molecular interactions of biglycan and decorin with elastic fiber components - Biglycan forms a ternary complex with tropoelastin and microfibril-associated glycoprotein 1

B Reinboth, E Hanssen, EG Cleary, MA Gibson

Journal article  |  2002  |  J Biol Chem

Synthesis and structural organization of zonular fibers during development and aging

E Hanssen, S Franc, R Garrone

Journal article  |  2001  |  Matrix Biol

"Beads-on-a-string" filaments: structure, functions and associated pathologies

E Hanssen, S Franc

Journal article  |  2001  |  médecine/sciences

Fibrillin-rich microfibrils: structural modifications during ageing in normal human zonule

E Hanssen, S Franc, R Garrone

Journal article  |  1998  |  J Submicrosc Cytol Pathol

Atomic force microscopy and modeling of natural elastic fibrillin polymers

E Hanssen, S Franc, R Garrone

Journal article  |  1998  |  Biol Cell

Purification of fibrillin-containing microfibrils and collagen VI microfibrils by density gradient centrifugation

CM Kielty, E Hanssen, CA Shuttleworth

Journal article  |  1998  |  Anal Biochem