Michael Leeming

Nontargeted Identification of Plasma Proteins O-, N-, and S-Transmethylated by O-Methyl Organophosphates

Huixin Wang, Michael G Leeming, Blake J Cochran, James M Hook, Junming Ho, Giang TH Nguyen, Ling Zhong, Claudiu T Supuran, William A Donald

Journal article  |  2020  |  Analytical Chemistry

Protonation isomers of highly charged protein ions can be separated in FAIMS-MS

J Diana Zhang, Micah T Donor, Amber D Rolland, Michael G Leeming, Huixin Wang, Adam J Trevitt, KM Mohibul Kabir, James S Prell, William A Donald

Journal article  |  2020  |  International Journal of Mass Spectrometry

Phosphomatics: Interactive interrogation of substrate-kinase networks in global phosphoproteomics datasets.

Michael G Leeming, Sean O'Callaghan, Luana Licata, Marta Iannuccelli, Prisca Lo Surdo, Elisa Micarelli, Ching-Seng Ang, Shuai Nie, Swati Varshney, Sadia Ameen, Heung-Chin Cheng, Nicholas A Williamson

Journal article  |  2020  |  Bioinformatics

MOTIVATION: Mass spectrometry-based phosphoproteomics can routinely identify and quantify thousands of phosphorylated peptides fro..

Expanding the allergen repertoire of salmon and catfish

Thimo Ruethers, Aya C Taki, Shaymaviswanathan Karnaneedi, Shuai Nie, Tanja Kalic, Danyi Dai, Sakda Daduang, Michael Leeming, Nicholas A Williamson, Heimo Breiteneder, Sam S Mehr, Sandip D Kamath, Dianne E Campbell, Andreas L Lopata

Journal article  |  2020  |  Allergy

BACKGROUND: Diagnostic tests for fish allergy are hampered by the large number of under-investigated fish species. Four salmon all..

Type IX Secretion System Cargo Proteins Are Glycosylated at the C Terminus with a Novel Linking Sugar of the Wbp/Vim Pathway

Paul D Veith, Mikio Shoji, Richard AJ O'Hair, Michael G Leeming, Shuai Nie, Michelle D Glew, Gavin E Reid, Koji Nakayama, Eric C Reynolds

Journal article  |  2020  |  mBio

Porphyromonas gingivalis and Tannerella forsythia use the type IX secretion system to secrete cargo proteins to the cell surface w..

Differential cleavage of viral polypeptides by allotypic variants of granzyme B skews immunity to mouse cytomegalovirus

Vivien R Sutton, Christopher Andoniou, Michael G Leeming, Colin M House, Sally Watt, Sandra Verschoor, Annette Ciccone, Ilia Voskoboinik, Mariapia Degli-Esposti, Joseph A Trapani

Journal article  |  2020  |  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

We investigated the molecular basis for the remarkably different survival outcomes of mice expressing different alloforms of the p..

HiTIME: An efficient model-selection approach for the detection of unknown drug metabolites in LC-MS data

Michael G Leeming, Andrew P Isaac, Luke Zappia, Richard AJ O'Hair, William A Donald, Bernard J Pope

Journal article  |  2020  |  SoftwareX

What are the Potential Sites of DNA Attack by N-Acetyl-p-benzoquinone Imine (NAPQI)?

Siqi Li, Michael G Leeming, Bun Chan, Richard AJ O'Hair

Journal article  |  2020  |  Australian Journal of Chemistry

Metabolic bioactivation of small molecules can produce electrophilic metabolites that can covalently modify proteins and DNA. Para..

Using high-resolution Twin-Ion Metabolite Extraction (HiTIME) mass spectrometry with stable isotope labelling to investigate the metabolism of valproic acid in vivo

Michael G Leeming, Noel Cranswick, Christine E Wright, James Ziogas, Terence J O'Brien, William A Donald, Richard AJ O'Hair

Journal article  |  2019  |  International Journal of Mass Spectrometry

IgE-reactive proteins defined by 88 fish-allergic children, predicting the allergenicity of 66 Asia-Pacific fish species

T Ruethers, AC Taki, R Nugraha, S Karnaneedi, TT Cao, D Dai, T Shanmuganathan, M Leeming, S Nie, NA Williamson, SS Mehr, DE Campbell, AL Lopata

Conference Proceedings  |  2019  |  ALLERGY