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Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte ..
Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P-2 posit..
Differing rates of antibody acquisition to merozoite antigens in malaria: implications for..
A novel approach to identifying patterns of human invasion-inhibitory antibodies guides th..
Exploration of the P-3 region of PEXEL peptidomimetics leads to a potent inhibitor of the ..
Displaying the 56 most recent scholarly works by Anthony Hodder.
Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex
Wilson Wong, Rick Huang, Sebastien Menant, Chuan Hong, Jarrod J Sandow, Richard W Birkinshaw, Julie Healer, Anthony N Hodder, Usheer Kanjee, Christopher J Tonkin, Denise Heckmann, Vladislav Soroka, Teit Max Moscote Sogaard, Thomas Jorgensen, Manoj T Duraisingh, Peter E Czabotar, Willem A de Jongh, Wai-Hong Tham, Andrew I Webb, Zhiheng Yu, et al.
Journal article | 2019 | Nature
Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte Membrane Protein 1-DBL beta Are Biomarkers of Protective Immunity to Malaria in a Cohort of Young Children from Papua New Guinea
Sofonias K Tessem, Digjaya Utama, Olga Chesnokov, Anthony N Hodder, Clara S Lin, GL Abby Harrison, Jakob S Jespersen, Bent Petersen, Livingstone Tavul, Peter Siba, Dominic Kwiatkowski, Thomas Lavstsen, Diana S Hansen, Andrew Oleinikov, Ivo Mueller, Alyssa E Barry
Journal article | 2018 | Infection and Immunity
Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P-2 position of PEXEL peptidomimetics
William Nguyen, Anthony N Hodder, Richard Bestel de Lezongard, Peter E Czabotar, Kate E Jarman, Matthew T O'Neill, Jennifer K Thompson, Helene Jousset Sabroux, Alan F Cowman, Justin A Boddey, Brad E Sleebs
Journal article | 2018 | European Journal of Medicinal Chemistry
Differing rates of antibody acquisition to merozoite antigens in malaria: implications for immunity and surveillance
Fiona J McCallum, Kristina EM Persson, Freya JI Fowkes, Linda Reiling, Cleopatra K Mugyenyi, Jack S Richards, Julie A Simpson, Thomas N Williams, Paul R Gilson, Anthony N Hodder, Paul R Sanders, Robin F Anders, David L Narum, Chetan Chitnis, Brendan S Crabb, Kevin Marsh, James G Beeson
Journal article | 2017 | Journal of Leukocyte Biology
A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens
Damien R Drew, Danny W Wilson, Salenna R Elliott, Nadia Cross, Ulrich Terheggen, Anthony N Hodder, Peter M Siba, Kiprotich Chelimo, Arlene E Dent, James W Kazura, Ivo Mueller, James G Beeson
Journal article | 2016 | BMC Medicine
Exploration of the P-3 region of PEXEL peptidomimetics leads to a potent inhibitor of the Plasmodium protease, plasmepsin V
Michelle Gazdik, Kate E Jarman, Matthew T O'Neill, Anthony N Hodder, Kym N Lowes, Helene Jousset Sabroux, Alan F Cowman, Justin A Boddey, Brad E Sleebs
Journal article | 2016 | Bioorganic & Medicinal Chemistry
Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding
Justin A Boddey, Matthew T O'Neill, Sash Lopaticki, Teresa G Carvalho, Anthony N Hodder, Thomas Nebl, Stephan Wawra, Pieter van West, Zeinab Ebrahimzadeh, Dave Richard, Sven Flemming, Tobias Spielmann, Jude Przyborski, Jeff J Babon, Alan F Cowman
Journal article | 2016 | Nature Communications
Structural basis for plasmep sin V inhibition that blocks export of malaria proteins to human erythrocytes
Anthony N Hodder, Brad E Sleebs, Peter E Czabotar, Michelle Gazdik, Yibin Xu, Matthew T O'Neill, Sash Lopaticki, Thomas Nebl, Tony Triglia, Brian J Smith, Kym Lowes, Justin A Boddey, Alan F Cowman
Journal article | 2015 | Nature Structural & Molecular Biology
Antibodies to the Plasmodium falciparum Proteins MSPDBL1 and MSPDBL2 Opsonize Merozoites, Inhibit Parasite Growth, and Predict Protection From Clinical Malaria
Chris YH Chiu, Anthony N Hodder, Clara S Lin, Danika L Hill, Connie SN Li Wai Suen, Louis Schofield, Peter M Siba, Ivo Mueller, Alan F Cowman, Diana S Hansen
Journal article | 2015 | Journal of Infectious Diseases
Limited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 supports the development of effective multi-allele vaccines
Ulrich Terheggen, Damien R Drew, Anthony N Hodder, Nadia J Cross, Cleopatra K Mugyenyi, Alyssa E Barry, Robin F Anders, Sheetij Dutta, Faith HA Osier, Salenna R Elliott, Nicolas Senn, Danielle I Stanisic, Kevin Marsh, Peter M Siba, Ivo Mueller, Jack S Richards, James G Beeson
Journal article | 2014 | BMC Medicine
The Merozoite Surface Protein 1 Complex Is a Platform for Binding to Human Erythrocytes by Plasmodium falciparum
Clara S Lin, Alessandro D Uboldi, Danushka Marapana, Peter E Czabotar, Christian Epp, Hermann Bujard, Nicole L Taylor, Matthew A Perugini, Anthony N Hodder, Alan F Cowman
Journal article | 2014 | Journal of Biological Chemistry
Synthetic peptides derived from the C-terminal 6 kDa region of Plasmodium falciparum SERA5 inhibit the enzyme activity and malaria parasite development
Shivani Kanodia, Gautam Kumar, Luca Rizzi, Alessandro Pedretti, Anthony N Hodder, Sergio Romeo, Pawan Malhotra
Journal article | 2014 | Biochimica et Biophysica Acta - General Subjects
Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites
Brad E Sleebs, Sash Lopaticki, Danushka S Marapana, Matthew T O'Neill, Pravin Rajasekaran, Michelle Gazdik, Svenja Guenther, Lachlan W Whitehead, Kym N Lowes, Lea Barfod, Lars Hviid, Philip J Shaw, Anthony N Hodder, Brian J Smith, Alan F Cowman, Justin A Boddey
Journal article | 2014 | PLoS Biology
Vaccination with Conserved Regions of Erythrocyte-Binding Antigens Induces Neutralizing Antibodies against Multiple Strains of Plasmodium falciparum
Julie Healer, Jennifer K Thompson, David T Riglar, Danny W Wilson, Yu-H C Chiu, Kazutoyo Miura, Lin Chen, Anthony N Hodder, Carole A Long, Diana S Hansen, Jake Baum, Alan F Cowman
Journal article | 2013 | PLoS One
Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to Plasmodium falciparum Malaria for Vaccine and Biomarker Development
Jack S Richards, Thangavelu U Arumugam, Linda Reiling, Julie Healer, Anthony N Hodder, Freya JI Fowkes, Nadia Cross, Christine Langer, Satoru Takeo, Alex D Uboldi, Jennifer K Thompson, Paul R Gilson, Ross L Coppel, Peter M Siba, Christopher L King, Motomi Torii, Chetan E Chitnis, David L Narum, Ivo Mueller, Brendan S Crabb, et al.
Journal article | 2013 | Journal of Immunology
Defining the Antigenic Diversity of Plasmodium falciparum Apical Membrane Antigen 1 and the Requirements for a Multi-Allele Vaccine against Malaria
Damien R Drew, Anthony N Hodder, Danny W Wilson, Michael Foley, Ivo Mueller, Peter M Siba, Arlene E Dent, Alan F Cowman, James G Beeson
Journal article | 2012 | PLoS ONE
Insights into Duffy Binding-like Domains through the Crystal Structure and Function of the Merozoite Surface Protein MSPDBL2 from Plasmodium falciparum
Anthony N Hodder, Peter E Czabotar, Alessandro D Uboldi, Oliver B Clarke, Clara S Lin, Julie Healer, Brian J Smith, Alan F Cowman
Journal article | 2012 | Journal of Biological Chemistry
Biochemical and Functional Analysis of Two Plasmodium falciparum Blood-Stage 6-Cys Proteins: P12 and P41
Tana Taechalertpaisarn, Cecile Crosnier, S Josefin Bartholdson, Anthony N Hodder, Jenny Thompson, Leyla Y Bustamante, Danny W Wilson, Paul R Sanders, Gavin J Wright, Julian C Rayner, Alan F Cowman, Paul R Gilson, Brendan S Crabb
Journal article | 2012 | PLoS One
Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils
Christopher G Adda, Vince J Murphy, Margaret Sunde, Lynne J Waddington, Jesse Schloegel, Gert H Talbo, Kleo Vingas, Vivian Kienzle, Rosella Masciantonio, Geoffrey J Howlett, Anthony N Hodder, Michael Foley, Robin F Anders
Journal article | 2009 | Molecular and Biochemical Parasitology
Analysis of structure and function of the giant protein Pf332 in Plasmodium falciparum
Anthony N Hodder, Alexander G Maier, Melanie Rug, Monica Brown, Mirja Hommel, Ivan Pantic, Marina Puig-de-Morales-Marinkovic, Brian Smith, Tony Triglia, James Beeson, Alan F Cowman
Journal article | 2009 | Mol. Microbiol.
Inhibition of malaria parasite development by a cyclic peptide that targets the vital parasite protein SERA5
W Douglas Fairlie, Tim P Spurck, Joanne E McCoubrie, Paul R Gilson, Susanne K Miller, Geoffrey I McFadden, Robyn Malby, Brendan S Crabb, Anthony N Hodder
Journal article | 2008 | Infection and Immunity
Evidence for a common role for the serine-type Plasmodium falciparum serine repeat antigen proteases: Implications for vaccine and drug design
Joanne E McCoubrie, Susanne K Miller, Tobias Sargeant, Robert T Good, Anthony N Hodder, Terence P Speed, Tania F de Koning-Ward, Brendan S Crabb
Journal article | 2007 | Infection and Immunity
Antigen delivery via two molecules on the CD8(-) dendritic cell subset induces humoral immunity in the absence of conventional "danger"
AJ Corbett, I Caminschi, BS McKenzie, JL Brady, MD Wright, PL Mottram, PM Hogarth, AN Hodder, YF Zhan, DM Tarlinton, K Shortman, AM Lew
Journal article | 2005 | European Journal of Immunology
A human phase 1 vaccine clinical trial of the Plasmodium falciparum malaria vaccine candidate apical membrane antigen 1 in Montanide ISA720 adjuvant
A Saul, G Lawrence, A Allworth, S Elliott, K Anderson, C Rzepczyk, LB Martin, D Taylor, DP Eisen, DO Irving, D Pye, PE Crewther, AN Hodder, VJ Murphy, RF Anders
Journal article | 2005 | Vaccine
CD4 T cells acting independently of antibody contribute to protective immunity to Plasmodium chabaudi infection after apical membrane antigen 1 immunization.
H Xu, AN Hodder, H Yan, PE Crewther, RF Anders, MF Good
Journal article | 2000 | The Journal of Immunology
Apical membrane Ag 1 (AMA1) is a leading malaria vaccine candidate. Homologues of AMA1 can induce protection in mice and monkeys, ..
Pathotyping isolates of Newcastle disease virus using antipeptide antibodies to pathotype-specific regions of their fusion and hemagglutinin-neuraminidase proteins.
DB Scanlon, GL Corino, BJ Shiell, AJ Della-Porta, RJ Manvell, DJ Alexander, AN Hodder, JJ Gorman
Journal article | 1999 | Archives of Virology
Antipeptide antibodies have been evaluated for their abilities to predict the characteristics of the cleavage motifs of the fusion..
Characterization of field isolates of Newcastle disease virus using antipeptide antibodies.
AN Hodder, ZY Liu, PW Selleck, GL Corino, BJ Shiell, DC Grix, CJ Morrow, JJ Gorman
Journal article | 1994 | Avian Diseases
A recent Australian field isolate of Newcastle disease virus (NDV) was analyzed with antipeptide antibodies capable of differentia..
Analysis of pathotype-specific structural features and cleavage activation of Newcastle disease virus membrane glycoproteins using antipeptide antibodies.
AN Hodder, PW Selleck, JR White, JJ Gorman
Journal article | 1993 | Journal of General Virology
Peptides were synthesized, that correspond to cleaved and trimmed carboxyl termini of the F2 polypeptide regions of fusion (F) pro..
Antipeptide antibodies for analysis of pathotype-specific variations in cleavage activation of the membrane glycoprotein precursors of Newcastle disease virus isolates in cultured cells.
JJ Gorman, AN Hodder, PW Selleck, E Hansson
Journal article | 1992 | Journal of Virological Methods
Antipeptide antibodies have been produced which target regions either side of the cleavage activation sites of Newcastle disease v..
Medical Biology (W.E.H.I.)