Philippe Bouillet

Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer

Paul M Nguyen, Laura F Dagley, Adele Preaudet, Nga Lam, Maybelline Giam, Ka Yee Fung, Kaheina Aizel, Gemma van Duijneveldt, Chin Wee Tan, Yumiko Hirokawa, Hon Yan K Yip, Christopher G Love, Ashleigh R Poh, Akshay D' Cruz, Charlotte Burstroem, Rebecca Feltham, Suad M Abdirahman, Kristy Meiselbach, Ronnie Ren Jie Low, Michelle Palmieri, et al.

Journal article  |  2020  |  Cell Death & Differentiation

Gastrointestinal epithelial cells provide a selective barrier that segregates the host immune system from luminal microorganisms, ..

CARD11 is dispensable for homeostatic responses and suppressive activity of peripherally induced FOXP3( ) regulatory T cells

Antonia Polichen, Keisuke Horikawa, Liz Milla, Jennifer Kofler, Philippe Bouillet, Gabrielle T Belz, Lorraine A O'Reilly, Christopher C Goodnow, Andreas Strasser, Daniel HD Gray

Journal article  |  2019  |  Immunology & Cell Biology

FOXP3+ regulatory T (Treg) cells are essential for immunological tolerance and immune homeostasis. Despite a great deal of interes..

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

Michael Chopin, Aaron T Lun, Yifan Zhan, Jaring Schreuder, Hannah Coughlan, Angela D'Amico, Lisa A Mielke, Francisca F Almeida, Andrew J Kueh, Ross A Dickins, Gabrielle T Belz, Shalin H Naik, Andrew M Lew, Phillipe Bouillet, Marco J Herold, Gordon K Smyth, Lynn M Corcoran, Stephen L Nutt

Journal article  |  2019  |  Immunity

Constitutive overexpression of TNF in BPSM1 mice causes iBALT and bone marrow nodular lymphocytic hyperplasia

Cyril Seillet, Elysa Carr, Derek Lacey, Michael D Stutz, Marc Pellegrini, Lachlan Whitehead, Joel Rimes, Edwin D Hawkins, Ben Roediger, Gabrielle T Belz, Philippe Bouillet

Journal article  |  2019  |  Immunology and Cell Biology

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and-7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1 beta Activation

James E Vince, Dominic De Nardo, Wenqing Gao, Angelina J Vince, Cathrine Hall, Kate McArthur, Daniel Simpson, Swarna Vijayaraj, Lisa M Lindqvist, Philippe Bouillet, Mark A Rizzacasa, Si Ming Man, John Silke, Seth L Masters, Guillaume Lessene, David CS Huang, Daniel HD Gray, Benjamin T Kile, Feng Shao, Kate E Lawlor

Journal article  |  2018  |  Cell Reports

VDAC2 enables BAX to mediate apoptosis and limit tumor development

Hui San Chin, Mark X Li, Iris KL Tan, Robert L Ninnis, Boris Reljic, Kristen Scicluna, Laura F Dagley, Jarrod J Sandow, Gemma L Kelly, Andre L Samson, Stephane Chappaz, Seong L Khaw, Catherine Chang, Andrew Morokoff, Kerstin Brinkmann, Andrew Webb, Colin Hockings, Cathrine M Hall, Andrew J Kueh, Michael T Ryan, et al.

Journal article  |  2018  |  Nature Communications

LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L

Lucia Taraborrelli, Nieves Peltzer, Antonella Montinaro, Sebastian Kupka, Eva Rieser, Torsten Hartwig, Aida Sarr, Maurice Darding, Peter Draber, Tobias L Haas, Ayse Akarca, Teresa Marafioti, Manolis Pasparakis, John Bertin, Peter J Gough, Philippe Bouillet, Andreas Strasser, Martin Leverkus, John Silke, Henning Walczak

Journal article  |  2018  |  Nature Communications

LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis

Nieves Peltzer, Maurice Darding, Antonella Montinaro, Peter Draber, Helena Draberova, Sebastian Kupka, Eva Rieser, Amanda Fisher, Ciaran Hutchinson, Lucia Taraborrelli, Torsten Hartwig, Elodie Lafont, Tobias L Haas, Yutaka Shimizu, Charlotta Boiers, Aida Sarr, James Rickard, Silvia Alvarez-Diaz, Michael T Ashworth, Allison Beal, et al.

Journal article  |  2018  |  Nature

Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner

Rui Liu, Ashleigh King, Philippe Bouillet, David M Tarlinton, Andreas Strasser, Jorg Heierhorst

Journal article  |  2018  |  Frontiers in Immunology

Bim suppresses the development of SLE by limiting myeloid inflammatory responses

FuNien Tsai, Philip J Homan, Hemant Agrawal, Alexander V Misharin, Hiam Abdala-Valencia, G Kenneth Haines, Salina Dominguez, Christina L Bloomfield, Rana Saber, Anthony Chang, Chandra Mohan, Jack Hutcheson, Anne Davidson, GR Scott Budinger, Philippe Bouillet, Andrea Dorfleutner, Christian Stehlik, Deborah R Winter, Carla M Cuda, Harris Perlman

Journal article  |  2017  |  Journal of Experimental Medicine

Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo

Emma M Carrington, Yifan Zhan, Jamie L Brady, Jian-Guo Zhang, Robyn M Sutherland, Natasha S Anstee, Robyn L Schenk, Ingela B Vikstrom, Rebecca B Delconte, David Segal, Nicholas D Huntington, Philippe Bouillet, David M Tarlinton, David CS Huang, Andreas Strasser, Suzanne Cory, Marco J Herold, Andrew M Lew

Journal article  |  2017  |  Cell Death & Differentiation

TNF-induced chronic inflammation does not affect tumorigenesis driven by p53 loss

Derek Lacey, Andreas Strasser, Philippe Bouillet

Journal article  |  2017  |  Cell Death & Disease

Male sterility in Mcl-1-flox mice is not due to enhanced Mcl1 protein stability

Casey Ah-Cann, Maximilien Tailler, Andrew J Kueh, Marco J Herold, Joseph T Opferman, Marie-Liesse Asselin-Labat, Philippe Bouillet

Journal article  |  2016  |  Cell Death & Disease

Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis

Charis E Teh, Najoua Lalaoui, Reema Jain, Antonia N Policheni, Melanie Heinlein, Silvia Alvarez-Diaz, Julie M Sheridan, Eva Rieser, Stefanie Deuser, Maurice Darding, Hui-Fern Koay, Yifang Hu, Fiona Kupresanin, Lorraine A O'Reilly, Dale I Godfrey, Gordon K Smyth, Philippe Bouillet, Andreas Strasser, Henning Walczak, John Silke, et al.

Journal article  |  2016  |  Nature Communications

Physiological restraint of Bak by Bcl-x(L) is essential for cell survival

Erinna F Lee, Stephanie Grabow, Stephane Chappaz, Grant Dewson, Colin Hockings, Ruth M Kluck, Marlyse A Debrincat, Daniel H Gray, Matthew T Witkowski, Marco Evangelista, Anne Pettikiriarachchi, Philippe Bouillet, Rachael M Lane, Peter E Czabotar, Peter M Colman, Brian J Smith, Benjamin T Kile, W Douglas Fairlie

Journal article  |  2016  |  Genes & Development

BCL2-modifying factor promotes germ cell loss during murine oogenesis

Kavitha Vaithiyanathan, Seng H Liew, Nadeen Zerafa, Thilini Gamage, Michele Cook, Lorraine A O'Reilly, Philippe Bouillet, Clare L Scott, Andreas Strasser, Jock K Findlay, Karla J Hutt

Journal article  |  2016  |  Reproduction

Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis

S Grabow, GL Kelly, ARD Delbridge, PN Kelly, P Bouillet, JM Adams, A Strasser

Journal article  |  2016  |  Cell Death & Disease

Is BOK required for apoptosis induced by endoplasmic reticulum stress?

Yuniel Fernandez-Marrero, Francine Ke, Nohemy Echeverry, Philippe Bouillet, Daniel Bachmann, Andreas Strasser, Thomas Kaufmann

Journal article  |  2016  |  Proceedings of the National Academy of Sciences

Deregulation of TNF expression can also cause heart valve disease

Derek Lacey, Philippe Bouillet

Journal article  |  2016  |  Cytokine

Spontaneous retrotransposon insertion into TNF 3'UTR causes heart valve disease and chronic polyarthritis

Derek Lacey, Peter Hickey, Benedicta D Arhatari, Lorraine A O'Reilly, Leona Rohrbeck, Helen Kiriazis, Xiao-Jun Du, Philippe Bouillet

Journal article  |  2015  |  Proceedings of the National Academy of Sciences

Pro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2

D Merino, SA Best, M-L Asselin-Labat, F Vaillant, B Pal, RA Dickins, RL Anderson, A Strasser, P Bouillet, GJ Lindeman, JE Visvader

Journal article  |  2015  |  Oncogene

Functional antagonism between pro-apoptotic BIM and anti-apoptotic BCL-XL in MYC-induced lymphomagenesis

ARD Delbridge, S Grabow, P Bouillet, JM Adams, A Strasser

Journal article  |  2015  |  Oncogene

EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival

Nai Yang Fu, Anne C Rios, Bhupinder Pal, Rina Soetanto, Aaron TL Lun, Kevin Liu, Tamara Beck, Sarah A Best, Francois Vaillant, Philippe Bouillet, Andreas Strasser, Thomas Preiss, Gordon K Smyth, Rey J Lindeman, Jane E Visvader

Journal article  |  2015  |  Nature Cell Biology

BCL-2 is dispensable for thrombopoiesis and platelet survival

MA Debrincat, I Pleines, M Lebois, RM Lane, ML Holmes, J Corbin, CJ Vandenberg, WS Alexander, AP Ng, A Strasser, P Bouillet, M Sola-Visner, BT Kile, EC Josefsson

Journal article  |  2015  |  Cell Death & Disease

Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

Emma M Carrington, Jian-Guo Zhang, Robyn M Sutherland, Ingela B Vikstrom, Jamie L Brady, Priscilla Soo, David Vremec, Cody Allison, Erinna F Lee, W Douglas Fairlie, Philippe Bouillet, Stephanie Grabow, Eleonora Ottina, Marco J Herold, Marc Pellegrini, David CS Huang, David M Tarlinton, Andreas Strasser, Andrew M Lew, Yifan Zhan

Journal article  |  2015  |  Proceedings of the National Academy of Sciences

Bcl-2 Antagonists Kill Plasmacytoid Dendritic Cells From Lupus-Prone Mice and Dampen Interferon-alpha Production

Yifan Zhan, Emma M Carrington, Hyun-Ja Ko, Ingela B Vikstrom, Shereen Oon, Jian-Guo Zhang, David Vremec, Jamie L Brady, Philippe Bouillet, Li Wu, David CS Huang, Ian P Wicks, Eric F Morand, Andreas Strasser, Andrew M Lew

Journal article  |  2015  |  Arthritis & Rheumatology

Pro-apoptotic BIM is an essential initiator of physiological endothelial cell death independent of regulation by FOXO3

MN Koenig, E Naik, L Rohrbeck, MJ Herold, E Trounson, P Bouillet, T Thomas, AK Voss, A Strasser, L Coultas

Journal article  |  2014  |  Cell Death & Differentiation

Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice

MJ Herold, R Stuchbery, D Merino, T Willson, A Strasser, D Hildeman, P Bouillet

Journal article  |  2014  |  Cell Death & Disease

Evidence against upstream regulation of the unfolded protein response (UPR) by pro-apoptotic BIM and PUMA

MJ Herold, LA O'Reilly, A Lin, R Srivastava, M Doerflinger, P Bouillet, A Strasser, H Puthalakath

Journal article  |  2014  |  Cell Death & Disease

Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199

SL Khaw, D Merino, MA Anderson, SP Glaser, P Bouillet, AW Roberts, DCS Huang

Journal article  |  2014  |  Leukemia

Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf

Verena Labi, Claudia Woess, Selma Tuzlak, Miriam Erlacher, Philippe Bouillet, Andreas Strasser, Alexandar Tzankov, Andreas Villunger

Journal article  |  2014  |  Blood

Loss of the Proapoptotic BH3-Only Protein BCL-2 Modifying Factor Prolongs the Fertile Life Span in Female Mice1

Seng H Liew, Kavitha Vaithiyanathan, Michele Cook, Philippe Bouillet, Clare L Scott, JB Kerr, Andreas Strasser, Jock K Findlay, Karla J Hutt

Journal article  |  2014  |  Biology of Reproduction

Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis

Toru Okamoto, Leigh Coultas, Donald Metcalf, Mark F van Delft, Stefan P Glaser, Megumi Takiguchi, Andreas Strasser, Philippe Bouillet, Jerry M Adams, David CS Huang

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

Gemma L Kelly, Stephanie Grabow, Stefan P Glaser, Leah Fitzsimmons, Brandon J Aubrey, Toru Okamoto, Liz J Valente, Mikara Robati, Lin Tai, W Douglas Fairlie, Erinna F Lee, Mikael S Lindstrom, Klas G Wiman, David CS Huang, Philippe Bouillet, Martin Rowe, Alan B Rickinson, Marco J Herold, Andreas Strasser

Journal article  |  2014  |  Genes & Development

Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein

Marco J Herold, Leona Rohrbeck, Mathias J Lang, Raelene Grumont, Steve Gerondakis, Lin Tai, Philippe Bouillet, Thomas Kaufmann, Andreas Strasser

Journal article  |  2013  |  EMBO Reports

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia

Gabriela Brumatti, Marika Salmanidis, Chung H Kok, Rebecca A Bilardi, Jarrod J Sandow, Natasha Silke, Kylie Mason, Jolanda Visser, Anissa M Jabbour, Stefan P Glaser, Toru Okamoto, Philippe Bouillet, Richard J D'Andrea, Paul G Ekert

Journal article  |  2013  |  Oncotarget

Hoxb8 regulates expression of microRNAs to control cell death and differentiation

M Salmanidis, G Brumatti, N Narayan, BD Green, JA van den Bergen, JJ Sandow, AG Bert, N Silke, R Sladic, H Puthalakath, L Rohrbeck, T Okamoto, P Bouillet, MJ Herold, GJ Goodall, AM Jabbour, PG Ekert

Journal article  |  2013  |  Cell Death & Differentiation

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3( ) regulatory T cells

Wim Pierson, Benedicte Cauwe, Antonia Policheni, Susan M Schlenner, Dean Franckaert, Julien Berges, Stephanie Humblet-Baron, Susann Schonefeldt, Marco J Herold, David Hildeman, Andreas Strasser, Philippe Bouillet, Li-Fan Lu, Patrick Matthys, Antonio A Freitas, Rita J Luther, Casey T Weaver, James Dooley, Daniel HD Gray, Adrian Liston

Journal article  |  2013  |  Nature Immunology

CREB-binding protein (CBP) regulates beta-adrenoceptor (beta-AR) - mediated apoptosis

YY Lee, D Moujalled, M Doerflinger, L Gangoda, R Weston, A Rahimi, I de Alboran, M Herold, P Bouillet, Q Xu, X Gao, X-J Du, H Puthalakath

Journal article  |  2013  |  Cell Death & Differentiation

Consequences of the combined loss of BOK and BAK or BOK and BAX

F Ke, P Bouillet, T Kaufmann, A Strasser, J Kerr, AK Voss

Journal article  |  2013  |  Cell Death & Disease

BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice (vol 19, pg 915, 2012)

F Ke, A Voss, JB Kerr, LA O'Reilly, L Tai, N Echeverry, P Bouillet, A Strasser, T Kaufmann

Journal article  |  2013  |  Cell Death & Differentiation

IL-5 fosters age-driven regulatory T cell accrual in the face of declining IL-2 levels

Jana Raynor, Allyson Sholl, David R Plas, Philippe Bouillet, Claire A Chougnet, David A Hildeman

Journal article  |  2013  |  Frontiers in Immunology

DNA Damage-Induced Primordial Follicle Oocyte Apoptosis and Loss of Fertility Require TAp63-Mediated Induction of Puma and Noxa

Jeffrey B Kerr, Karla J Hutt, Ewa M Michalak, Michele Cook, Cassandra J Vandenberg, Seng H Liew, Philippe Bouillet, Alea Mills, Clare L Scott, Jock K Findlay, Andreas Strasser

Journal article  |  2012  |  Molecular Cell

Bcl-2 family member Bcl-G is not a proapoptotic protein

M Giam, T Okamoto, JD Mintern, A Strasser, P Bouillet

Journal article  |  2012  |  Cell Death & Disease

The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens

Daniel HD Gray, Fiona Kupresanin, Stuart P Berzins, Marco J Herold, Lorraine A O'Reilly, Philippe Bouillet, Andreas Strasser

Journal article  |  2012  |  Immunity

Anti-apoptotic gene Bcl2 is required for stapes development and hearing

MR Carpinelli, AK Wise, BD Arhatari, P Bouillet, SSM Manji, MG Manning, AA Cooray, RA Burt

Journal article  |  2012  |  Cell Death & Disease

Detection of Bcl-2 family member Bcl-G in mouse tissues using new monoclonal antibodies

M Giam, JD Mintern, GJP Rautureau, MG Hinds, A Strasser, P Bouillet

Journal article  |  2012  |  Cell Death & Disease

Bim must be able to engage all pro-survival Bcl-2 family members for efficient tumor suppression

D Merino, A Strasser, P Bouillet

Journal article  |  2012  |  Oncogene

Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells

Delphine Merino, Seong L Khaw, Stefan P Glaser, Daniel J Anderson, Lisa D Belmont, Chihunt Wong, Peng Yue, Mikara Robati, Belinda Phipson, Walter D Fairlie, Erinna F Lee, Kirsteen J Campbell, Cassandra J Vandenberg, Suzanne Cory, Andrew W Roberts, Mary JC Ludlam, David CS Huang, Philippe Bouillet

Journal article  |  2012  |  Blood

BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice

F Ke, A Voss, JB Kerr, LA O'Reilly, L Tai, N Echeverry, P Bouillet, A Strasser, T Kaufmann

Journal article  |  2012  |  Cell Death & Differentiation

Alternative splicing of Bim and Erk-mediated Bim(EL) phosphorylation are dispensable for hematopoietic homeostasis in vivo

C Clybouw, D Merino, T Nebl, F Masson, M Robati, L O'Reilly, A Huebner, RJ Davis, A Strasser, P Bouillet

Journal article  |  2012  |  Cell Death & Differentiation

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

Stefan P Glaser, Erinna F Lee, Evelyn Trounson, Philippe Bouillet, Andrew Wei, W Douglas Fairlie, David J Izon, Johannes Zuber, Amy R Rappaport, Marco J Herold, Warren S Alexander, Scott W Lowe, Lorraine Robb, Andreas Strasser

Journal article  |  2012  |  Genes & Development

Death receptor-induced apoptosis signalling - essential guardian against autoimmune disease

Andreas Strasser, Lorraine A O'Reilly, Philipp Jost, Thomas Kaufmann, Stephanie Grabow, Elizabeth Kruse, Lin Tai, Mark Smyth, Philippe Bouillet

Conference Proceedings  |  2012  |  ARTHRITIS RESEARCH & THERAPY

Regulation of memory B-cell survival by the BH3-only protein Puma

Cyril Clybouw, Silke Fischer, Marie Therese Auffredou, Patricia Hugues, Catherine Alexia, Philippe Bouillet, Martine Raphael, Gerald Leca, Andreas Strasser, David M Tarlinton, Aime Vazquez

Journal article  |  2011  |  Blood

Can the analysis of BH3-only protein knockout mice clarify the issue of 'direct versus indirect' activation of Bax and Bak?

A Villunger, V Labi, P Bouillet, J Adams, A Strasser

Journal article  |  2011  |  Cell Death Differ.

Defects in the Bcl-2-Regulated Apoptotic Pathway Lead to Preferential Increase of CD25(low)Foxp3( ) Anergic CD4( ) T Cells

Yifan Zhan, Yuxia Zhang, Daniel Gray, Emma M Carrington, Philippe Bouillet, Hyun-Ja Ko, Lorraine O'Reilly, Ian P Wicks, Andreas Strasser, Andrew M Lew

Journal article  |  2011  |  Journal of Immunology

Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1

Ben A Croker, Joanne A O'Donnell, Cameron J Nowell, Donald Metcalf, Grant Dewson, Kirsteen J Campbell, Kelly L Rogers, Yifang Hu, Gordon K Smyth, Jian-Guo Zhang, Michael White, Kurt Lackovic, Louise H Cengia, Lorraine A O'Reilly, Philippe Bouillet, Suzanne Cory, Andreas Strasser, Andrew W Roberts

Journal article  |  2011  |  Proceedings of the National Academy of Sciences of the United States of America

Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells

Edwina Naik, Lorraine A O'Reilly, Marie-Liesse Asselin-Labat, Delphine Merino, Ann Lin, Michele Cook, Leigh Coultas, Philippe Bouillet, Jerry M Adams, Andreas Strasser

Journal article  |  2011  |  Journal of Experimental Medicine

Type I Interferon Drives Dendritic Cell Apoptosis via Multiple BH3-Only Proteins following Activation by PolyIC In Vivo

Silvia A Fuertes Marraco, Clare L Scott, Philippe Bouillet, Annette Ives, Slavica Masina, David Vremec, Elisa S Jansen, Lorraine A O'Reilly, Pascal Schneider, Nicolas Fasel, Ken Shortman, Andreas Strasser, Hans Acha-Orbea

Journal article  |  2011  |  PLoS One

Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage

A Badmann, A Keough, T Kaufmann, P Bouillet, T Brunner, N Corazza

Journal article  |  2011  |  Cell Death & Disease

Accuracy of computed tomographic colonography in a nationwide multicentre trial, and its relation to radiologist expertise.

D Heresbach, M Djabbari, F Riou, C Marcus, A Le Sidaner, MA Pierredon-Foulogne, T Ponchon, M Boudiaf, JA Seyrig, H Laumonier, D Luet, M Giraud-Cohen, AL Pelletier, A Charachon, F Ramaholimihaso, P Bouillet, M Veyrac, S Ficarelli, K Vahedi, J Keruhel, et al.

Journal article  |  2011  |  Gut

OBJECTIVE: Reports on the accuracy of computed tomographic colonography (CTC) mainly involve series from expert institutions. The ..

Apoptosis and cell survival in the immune system

D Mérino, P Bouillet

Book Chapter  |  2011

Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory

Ingela Vikstrom, Sebastian Carotta, Katja Luethje, Victor Peperzak, Philipp J Jost, Stefan Glaser, Meinrad Busslinger, Philippe Bouillet, Andreas Strasser, Stephen L Nutt, David M Tarlinton

Journal article  |  2010  |  Science

Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation

Karen A Fortner, Philippe Bouillet, Andreas Strasser, Ralph C Budd

Journal article  |  2010  |  Eur. J. Immunol.

Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance

Kirsteen J Campbell, Mary L Bath, Marian L Turner, Cassandra J Vandenberg, Philippe Bouillet, Donald Metcalf, Clare L Scott, Suzanne Cory

Journal article  |  2010  |  Blood

Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development

PN Kelly, MJ White, MW Goschnick, KA Fairfax, DM Tarlinton, SA Kinkel, P Bouillet, JM Adams, BT Kile, A Strasser

Journal article  |  2010  |  Cell Death & Differentiation

Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax

Mark D McKenzie, Emma Jamieson, Elisa S Jansen, Clare L Scott, David CS Huang, Philippe Bouillet, Janette Allison, Thomas WH Kay, Andreas Strasser, Helen E Thomas

Journal article  |  2010  |  Diabetes

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

Stephen Malin, Shane McManus, Cesar Cobaleda, Maria Novatchkova, Alessio Delogu, Philippe Bouillet, Andreas Strasser, Meinrad Busslinger

Journal article  |  2010  |  Nature Immunology

Antiapoptotic molecule Bcl-2 is essential for the anabolic activity of parathyroid hormone in bone

Yuichi Nagase, Mitsuyasu Iwasawa, Toru Akiyama, Naoshi Ogata, Yuho Kadono, Masaki Nakamura, Yasushi Oshima, Tetsuro Yasui, Takumi Matsumoto, Hironari Masuda, Philippe Bouillet, Kozo Nakamura, Sakae Tanaka

Conference Proceedings  |  2010  |  Annals of the New York Academy of Sciences

Anti-apoptotic Molecule Bcl-2 Regulates the Differentiation, Activation, and Survival of Both Osteoblasts and Osteoclasts

Yuichi Nagase, Mitsuyasu Iwasawa, Toru Akiyama, Yuho Kadono, Masaki Nakamura, Yasushi Oshima, Tetsuro Yasui, Takumi Matsumoto, Jun Hirose, Hiroaki Nakamura, Takeshi Miyamoto, Philippe Bouillet, Kozo Nakamura, Sakae Tanaka

Journal article  |  2009  |  Journal of Biological Chemistry

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

Lorraine A O' Reilly, Lin Tai, Lily Lee, Elizabeth A Kruse, Stephanie Grabow, W Douglas Fairlie, Nicole M Haynes, David M Tarlinton, Jian-Guo Zhang, Gabrielle T Belz, Mark J Smyth, Philippe Bouillet, Lorraine Robb, Andreas Strasser

Journal article  |  2009  |  Nature

XIAP discriminates between type I and type II FAS-induced apoptosis

Philipp J Jost, Stephanie Grabow, Daniel Gray, Mark D McKenzie, Ueli Nachbur, David CS Huang, Philippe Bouillet, Helen E Thomas, Christoph Borner, John Silke, Andreas Strasser, Thomas Kaufmann

Journal article  |  2009  |  Nature

The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins

Delphine Merino, Maybelline Giam, Peter D Hughes, Owen M Siggs, Klaus Heger, Lorraine A O'Reilly, Jerry M Adams, Andreas Strasser, Erinna F Lee, Walter D Fairlie, Philippe Bouillet

Journal article  |  2009  |  Journal of Cell Biology

CD95, BIM and T cell homeostasis

Philippe Bouillet, Lorraine A O'Reilly

Journal article  |  2009  |  Nature Reviews Immunology

Chemotherapy response evaluation in metastatic colorectal cancer with FDG PET/CT and CT scans.

J Monteil, N Mahmoudi, S Leobon, PY Roudaut, A El Badaoui, S Verbeke, L Venat-Bouvet, J Martin, V Le Brun-Ly, S Lavau-Denes, A Maubon, P Bouillet, M Pouquet, JC Vandroux, N Tubiana-Mathieu

Journal article  |  2009  |  Anticancer Research

BACKGROUND: [18F]-fluorodeoxyglucose with positron-emission tomography (PET) and computed tomography (CT) scans were used to asses..

The anterior intermeniscal ligament of the knee: an anatomic and MR study.

Pierre-Sylvain Marcheix, Bertrand Marcheix, Julien Siegler, Philippe Bouillet, Patrick Chaynes, Denis Valleix, Christian Mabit

Journal article  |  2009  |  Surgical and Radiologic Anatomy

BACKGROUND: The purposes of this study were to identify the presence of the anterior intermeniscal ligament of the knee (AIL), to ..

The Bcl-2 family in autoimmune and degenerative disorders

Delphine Merino, Philippe Bouillet

Journal article  |  2009  |  Apoptosis

A tumor suppressor function for caspase-2

Lien Ha Ho, Robyn Taylor, Loretta Dorstyn, Dimitrios Cakouros, Philippe Bouillet, Sharad Kumar

Journal article  |  2009  |  Proceedings of the National Academy of Sciences

Fatal Hepatitis Mediated by Tumor Necrosis Factor TNF alpha Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim

Thomas Kaufmann, Philipp J Jost, Marc Pellegrini, Hamsa Puthalakath, Raffi Gugasyan, Steve Gerondakis, Erika Cretney, Mark J Smyth, John Silke, Razq Hakem, Philippe Bouillet, Tak W Mak, Vishva M Dixit, Andreas Strasser

Journal article  |  2009  |  Immunity

BH3-only proteins and their roles in programmed cell death

M Giam, DCS Huang, P Bouillet

Journal article  |  2008  |  Oncogene

Intrahepatic murine CD8 T-Cell activation associates with a distinct phenotype leading to Bim-dependent death

Lauren E Holz, Volker Benseler, David G Bowen, Philippe Bouillet, Andreas Strasser, Lorraine O'Reilly, William MH D'Avigdor, Alex G Bishop, Geoffrey W McCaughan, Patrick Bertolino

Journal article  |  2008  |  Gastroenterology

MicroRNAs and lymphocyte homeostasis - Dangerous eggs in a single basket

Delphine Merino, Philippe Bouillet

Journal article  |  2008  |  IMMUNOLOGY AND CELL BIOLOGY

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

Peter D Hughes, Gabrielle T Belz, Karen A Fortner, Ralph C Budd, Andreas Strasser, Philippe Bouillet

Journal article  |  2008  |  Immunity

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

Erinna F Lee, Peter E Czabotar, Mark F Van Delft, Ewa M Michalak, Michelle J Boyle, Simon N Willis, Hamsa Puthalakath, Philippe Bouillet, Peter M Colman, David CS Huang, W Douglas Fairlie

Journal article  |  2008  |  Journal of Cell Biology

What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain

Andreas Strasser, Hamsa Puthalakath, Lorraine A O'Reilly, Philippe Bouillet

Journal article  |  2008  |  Immunol. Cell Biol.

Proapoptotic BH3-only protein Bim is essential for developmentally programmed death of germinal center-derived memory B cells and antibody-forming cells

Silke F Fischer, Philippe Bouillet, Kristy O'Donnell, Amanda Light, David M Tarlinton, Andreas Strasser

Journal article  |  2007  |  Blood

Bim expression indicates the pathway to retinal cell death in development and degeneration

Francesca Doonan, Maryanne Donovan, Violeta Gomez-Vicente, Philippe Bouillet, Thomas G Cotter

Journal article  |  2007  |  Journal of Neuroscience

ER stress triggers apoptosis by activating BH3-only protein Bim

Hamsa Puthalakath, Lorraine A O'Reilly, Priscilla Gunn, Lily Lee, Priscilla N Kelly, Nicholas D Huntington, Peter D Hughes, Ewa M Michalak, Jennifer McKimm-Breschkin, Noburo Motoyama, Tomomi Gotoh, Shizuo Akira, Philippe Bouillet, Andreas Strasser

Journal article  |  2007  |  Cell

Hrk/DP5 contributes to the apoptosis of select neuronal populations but is dispensable for haematopoietic cell apoptosis

Leigh Coultas, Susanna Terzano, Tim Thomas, Anne Voss, Kate Reid, Edouard G Stanley, Clare L Scott, Philippe Bouillet, Perry Bartlett, Jonathan Ham, Jerry M Adams, Andreas Strasser

Journal article  |  2007  |  J. Cell Sci.

Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease

Celine Perier, Jordi Bove, Du-Chu Wu, Benjamin Dehay, Dong-Kug Choi, Vernice Jackson-Lewis, Silvia Rathke-Hartlieb, Philippe Bouillet, Andreas Strasser, Joerg B Schulz, Serge Przedborski, Miquel Vila

Journal article  |  2007  |  Proc. Natl. Acad. Sci. U. S. A.

BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms

Arnaud A Mailleux, Michael Overholtzer, Tobias Schmelzle, Philippe Bouillet, Andreas Strasser, Joan S Brugge

Journal article  |  2007  |  Dev. Cell

Erratum: Bim and Bad mediate imatinib-induced killing of Bcr/Abl leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic (Proceedings of the National Academy of Sciences of the United States of America (October 3, 2006) 40, 103 (14907-14912) DOI: 10.1073/pnas.0606176103)

J Kuroda, H Puthalakath, MS Cragg, PN Kelly, P Bouillet, DCS Huang, S Kimura, OG Ottmann, BJ Druker, A Villunger, AW Roberts, A Strasser

Journal article  |  2006  |  Proceedings of the National Academy of Sciences

"Bim and Bad mediate imatinib-induced killing of Bcr/Abl( ) leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic" (vol 103, pg 14907, 2006)

Junya Kuroda, Hamsa Puthalakath, Mark S Cragg, Priscilla N Kelly, Philippe Bouillet, David CS Huang, Shinya Kimura, Oliver G Ottmann, Brian J Druker, Andreas Villunger, Andrew W Roberts, Andreas Strasser

Journal article  |  2006  |  Proc. Natl. Acad. Sci. U. S. A.

Selective involvement of BH3-only Bcl-2 family members Bim and Bad in neonatal hypoxia-ischemia

Jayne M Ness, Cary A Harvey, Andreas Strasser, Philippe Bouillet, Barbara J Klocke, Kevin A Roth

Journal article  |  2006  |  Brain Res.

Loss of PKD1 and loss of Bcl-2 elicit polycystic kidney disease through distinct mechanisms

P Hughes, M Robati, W Lu, J Zhou, A Strasser, P Bouillet

Journal article  |  2006  |  Cell Death Differ.

The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis

Takashi Yano, Kosei Ito, Hiroshi Fukamachi, Xin-Zi Chi, Hee-Jun Wee, Ken-ichi Inoue, Hiroshi Ida, Philippe Bouillet, Andreas Strasser, Suk-Chul Bae, Yoshiaki Ito

Journal article  |  2006  |  Mol. Cell. Biol.

Adenosine A(2A) receptor-mediated cell death of mouse thymocytes involves adenylate cyclase and Bim and is negatively regulated by Nur77

Ildiko Kiss, Henriett Oskolas, Reka Toth, Philippe Bouillet, Katalin Toth, Andras Fulop, Beata Scholtz, Catherine Ledent, Laszlo Fesus, Zsuzsa Szondy

Journal article  |  2006  |  European Journal of Immunology

Pelvic congestion syndrome and pelvic varices: Diagnosis and treatment

A Faury, M Pouquet, P Bouillet, A Maubon

Journal article  |  2006  |  Revue du Praticien - Gynecologie et Obstetrique

Role of Bim and other Bcl-2 family members in autoimmune and degenerative diseases.

Peter Hughes, Philippe Bouillet, Andreas Strasser

Journal article  |  2006  |  Current directions in autoimmunity

Apoptosis is essential for the development, function and homeostasis of the immune system. Experiments with transgenic and gene kn..

Concomitant loss of proapoptotic BH3-only bcl-2 antagonists Bik and Bim arrests spermatogenesis

L Coultas, P Bouillet, KL Loveland, S Meachem, H Perlman, JM Adams, A Strasser

Journal article  |  2005  |  EMBO J.

NKT cell stimulation with glycolipid antigen in vivo: Costimulation-dependent expansion, Bim-dependent contraction, and hyporesponsiveness to further antigenic challenge

AP Uldrich, NY Crowe, K Kyparissoudis, DG Pellicci, YF Zhan, AM Lew, P Bouillet, A Strasser, MJ Smyth, DI Godfrey

Journal article  |  2005  |  Journal of Immunology

Polycystic kidney disease prevented by transgenic RNA interference

P Bouillet, M Robati, M Bath, A Strasser

Journal article  |  2005  |  Cell Death Differ.

Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis

J Hutcheson, JC Scatizzi, E Bickel, NJ Brown, P Bouillet, A Strasser, H Perlman

Journal article  |  2005  |  J. Exp. Med.

Complications and survival following radiologically and endoscopically-guided gastrostomy in patients with amyotrophic lateral sclerosis.

Jean-Claude Desport, Tarek Mabrouk, Philippe Bouillet, Abuyaba Perna, Pierre-Marie Preux, Philippe Couratier

Journal article  |  2005  |  Amyotrophic Lateral Sclerosis

In the natural progression of amyotrophic lateral sclerosis (ALS), a state of malnutrition often develops, associated with reduced..

In vitro and in vivo assays for osteoclast apoptosis

T Akiyama, T Miyazaki, P Bouillet, K Nakamura, A Strasser, S Tanaka

Journal article  |  2005  |  Biol. Proc. Online

[Post-traumatic renal arteriovenous fistula discovered after 28 years].

Nicolas Lesaux, Pascal Paulhac, Philippe Bouillet, Xavier Plainard, Pierre Colombeau, Jean-Philippe Dumas

Journal article  |  2005  |  Progres en Urologie

There is only one published case of arteriovenous fistula discovered 20 years after firearm trauma. The authors report the case of..

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy

TT Tan, K Degenhardt, DA Nelson, B Beaudoin, W Nieves-Neira, P Bouillet, A Villunger, JM Adams, E White

Journal article  |  2005  |  Cancer Cell

Subversion of the Bcl-2 life/death switch in cancer development and therapy

JM Adams, DCS Huang, A Strasser, S Willis, L Chen, A Wei, M Van Delft, JI Fletcher, H Puthalakath, J Kuroda, EM Michalak, PN Kelly, P Bouillet, A Villunger, L O'Reilly, ML Bath, DP Smith, A Egle, AW Harris, M Hinds, et al.

Journal article  |  2005  |  Cold Spring Harbor Symp. Quant. Biol.

Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice

M Pellegrini, P Bouillet, M Robati, GT Belz, GM Davey, A Strasser

Journal article  |  2004  |  Journal of Experimental Medicine

Interleukin (IL)-7 receptor (R) signaling is essential for T and B lymphopoiesis by promoting proliferation, differentiation, and ..

Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice

M Pellegrini, P Bouillet, M Robati, GT Belz, GM Davey, A Strasser

Journal article  |  2004  |  J. Exp. Med.

Negative selection of seminature CD4( )8(-)HSA( ) thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling

A Villunger, VS Marsden, YF Zhan, M Erlacher, AM Lew, P Bouillet, S Berzins, DI Godfrey, WR Heath, A Strasser

Journal article  |  2004  |  Proceedings of the National Academy of Sciences of the United States of America

Bim is a suppressor of Myc-induced mouse B cell leukemia

A Egle, AW Harris, P Bouillet, S Cory

Journal article  |  2004  |  Proceedings of the National Academy of Sciences

Pre-irradiation chemotherapy for newly diagnosed high grade astrocytoma.

N Tubiana Mathieu, D Genet, F Labrousse, P Bouillet, S Lavau Denes, J Martin, JL Labourey, L Venat, P Clavere, JJ Moreau

Journal article  |  2004  |  Anticancer Research

The purpose of this work was to determine the response rate and toxicity of a combination of Carmustine and Cisplatin administered..

Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death

L Coultas, P Bouillet, EG Stanley, TC Brodnicki, JM Adams, A Strasser

Journal article  |  2004  |  Mol. Cell. Biol.

Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim

T Akiyama, P Bouillet, T Miyazaki, Y Kadono, H Chikuda, UG Chung, A Fukuda, A Hikita, H Seto, T Okada, T Inaba, A Sanjay, R Baron, H Kawaguchi, H Oda, K Nakamura, A Strasser, S Tanaka

Journal article  |  2003  |  EMBO J.

Loss of pro-apoptotic BH3-only Bcl-2 family member Bim does not protect mutant Lurcher mice from neurodegeneration

P Bouillet, M Robati, JM Adams, A Strasser

Journal article  |  2003  |  J. Neurosci. Res.

Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

M Pellegrini, G Belz, P Bouillet, A Strasser

Journal article  |  2003  |  Proceedings of the National Academy of Sciences of the United States of America

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells

A Enders, P Bouillet, H Puthalakath, YK Xu, DM Tarlinton, A Strasser

Journal article  |  2003  |  J. Exp. Med.

The control of apoptosis in lymphocyte selection

A Strasser, P Bouillet

Journal article  |  2003  |  Immunol. Rev.

Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival

A Villunger, C Scott, P Bouillet, A Strasser

Journal article  |  2003  |  Blood

Role of BH3-only protein Bim in autoimmune and degenerative diseases.

P Bouillet, S Cory, J Adams, A Strasser

Journal article  |  2003  |  Arthritis Research & Therapy

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

VS Marsden, L O'Connor, LA O'Reilly, J Silke, D Metcalf, PG Ekert, DCS Huang, F Cecconi, K Kuida, KJ Tomaselli, S Roy, DW Nicholson, DL Vaux, P Bouillet, JM Adams, A Strasser

Journal article  |  2002  |  Nature

Bax and Bak: back-bone of T cell death

P Bouillet, A Strasser

Journal article  |  2002  |  Nat. Immunol.

Erratum: BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes (Nature (2002) 415 (922-926))

P Bouillet, JF Purton, DI Godfrey, LC Zhang, L Coultas, H Puthalakath, M Pellegrini, S Cory, JM Adams, A Strasser

Journal article  |  2002  |  Nature

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes (vol 415, pg 922, 2002)

P Bouillet, JF Purton, DI Godfrey, LC Zhang, L Coultas, H Puthalakath, M Pellegrini, S Cory, JM Adams, A Strasser

Journal article  |  2002  |  Nature

Activated T cell death in vivo mediated by proapoptotic Bcl-2 family member Bim

DA Hildeman, YN Zhu, TC Mitchell, P Bouillet, A Strasser, J Kappler, P Marrack

Journal article  |  2002  |  Immunity

BH3-only proteins - Evolutionarily conserved pro-apoptotic Bcl-2 family members essential for initiating programmed cell death

P Bouillet, A Strasser

Journal article  |  2002  |  Journal of Cell Science

BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death

P Bouillet, A Strasser

Journal article  |  2002  |  J. Cell Sci.

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

P Bouillet, JF Purton, DI Godfrey, LC Zhang, L Coultas, H Puthalakath, M Pellegrini, S Cory, JM Adams, A Strasser

Journal article  |  2002  |  Nature

Avancées récentes en IRM des voies biliaires

P Bouillet

Journal article  |  2002  |  Acta Endoscopica

Les protéines à BH3-seulement à l’origine de maladies autoimmunes ou dégénératives ?

P Bouillet

Journal article  |  2002  |  médecine/sciences

Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist bim

P Bouillet, S Cory, LC Zhang, A Strasser, JM Adams

Journal article  |  2001  |  Dev. Cell

Value of magnetic resonance cholangiography in the preoperative diagnosis of common bile duct stones.

A Laokpessi, P Bouillet, D Sautereau, F Cessot, JC Desport, A Le Sidaner, B Pillegand

Journal article  |  2001  |  American Journal of Gastroenterology

OBJECTIVE: The aim of this study was to assess the performance of magnetic resonance cholangiography (MRC) in the preoperative dia..

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

GV Putcha, KL Moulder, JP Golden, P Bouillet, JA Adams, A Strasser, EM Johnson

Journal article  |  2001  |  Neuron

Gene structure, alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim

P Bouillet, LC Zhang, DCS Huang, GC Webb, CDK Bottema, P Shore, HJ Eyre, GR Sutherland, JM Adams

Journal article  |  2001  |  Mammalian Genome

Differential expression of retinoic acid-inducible (Stra) genes during mouse placentation

V Sapin, P Bouillet, M Oulad-Abdelghani, B Dastugue, P Chambon, P Dolle

Journal article  |  2000  |  Mechanisms of Development

How, when, and why do lymphocytes die?

A Strasser, K Newton, LA O'Reilly, M Pellegrini, L O'Connor, H Puthalakath, L Cullen, L Tai, L Coultas, DCS Huang, A Villunger, P Bouillet, ML Bath, DL Vaux, S Cory, JM Adams, AW Harris

Journal article  |  2000  |  Immunologist

The role of the pro-apoptotic bcl-2 family member Bim in physiological cell death

P Bouillet, DCS Huang, LA O'Reilly, H Puthalakath, L O'Connor, S Cory, JM Adams, A Strasser

Conference Proceedings  |  2000  |  Annals of the New York Academy of Sciences

The role of Bim, a proapoptotic BH3-only member of the Bcl-2 family, in cell-death control

A Strasser, H Puthalakath, P Bouillet, DCS Huang, L O'Connor, L O'Reilly, L Cullen, S Cory, JM Adams

Conference Proceedings  |  2000  |  Annals of the New York Academy of Sciences

Proapoptotic Bcl-2 relative bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

P Bouillet, D Metcalf, DCS Huang, DM Tarlinton, TWH Kay, F Kontgen, JM Adams, A Strasser

Journal article  |  1999  |  Science

[Simplified exploration of jaundice: cholangiography with magnetic resonance imaging].

A Gainant, P Bouillet

Journal article  |  1999  |  Journal de Chirurgie

Control of apoptosis in hematopoietic cells by the Bcl-2 family of proteins

JM Adams, DCS Huang, H Puthalakath, P Bouillet, G Vairo, K Moriishi, G Hausmann, L O'Reilly, K Newton, S Ogilvy, ML Bath, CG Print, AW Harris, A Strasser, S Cory

Conference Proceedings  |  1999  |  Cold Spring Harbor Symposia on Quantitative Biology

Value of MR cholangiography in the diagnosis of obstructive diseases of the biliary tree: a study of 58 cases.

MH Mendler, P Bouillet, D Sautereau, P Chaumerliac, F Cessot, A Le Sidaner, B Pillegand

Journal article  |  1998  |  The American Journal of Gastroenterology

OBJECTIVE: The aim of this study was to evaluate magnetic resonance cholangiography (MRC) in the diagnosis of biliary tree obstruc..

Dual-energy CT in the diagnosis and quantification of fatty liver: limited clinical value in comparison to ultrasound scan and single-energy CT, with special reference to iron overload.

MH Mendler, P Bouillet, A Le Sidaner, E Lavoine, F Labrousse, D Sautereau, B Pillegand

Journal article  |  1998  |  Journal of Hepatology

BACKGROUND/AIMS: It has been suggested that dual-energy CT could differentiate irregular fatty liver from other hypodense lesions...

Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily

M Oulad-Abdelghani, C Chazaud, P Bouillet, MG Mattei, P Dolle, P Chambon

Journal article  |  1998  |  International Journal of Developmental Biology

[A feminist poem: searching for the author].

C Scotto, VL Ratti, JY Salles, P Soria, L Delaire, P Bouillet, E Liozon, E Vidal

Conference Proceedings  |  1998  |  La Revue de Médecine Interne

Meis2, a novel mouse Pbx-related homeobox gene induced by retinoic acid during differentiation of P19 embryonal carcinoma cells

M OuladAbdelghani, C Chazaud, P Bouillet, V Sapin, P Chambon, P Dolle

Journal article  |  1997  |  Developmental Dynamics

Overexpression of Stra13 a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells

M Boudjelal, R Taneja, S Matsubara, P Bouillet, P Dolle, P Chambon

Journal article  |  1997  |  Genes & Development

Developmental expression pattern of Stra6, a retinoic acid-responsive gene encoding a new type of membrane protein

P Bouillet, V Sapin, C Chazaud, N Messaddeq, D Decimo, P Dolle, P Chambon

Journal article  |  1997  |  Mechanisms of Development

Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene

M OuladAbdelghani, P Bouillet, D Decimo, A Gansmuller, S Heyberger, P Dolle, S Bronner, Y Lutz, P Chambon

Journal article  |  1996  |  The Journal of Cell Biology

Evaluation of magnetic resonance imaging for the detection of sacroiliitis in patients with early seronegative spondylarthropathy.

M Rémy, P Bouillet, P Bertin, AF Leblanche, C Bonnet, JL Pascaud, MP Boncoeur-Martel, R Trèves

Journal article  |  1996  |  Revue du Rhumatisme (English Edition)

A prospective study was conducted in 23 patients to evaluate magnetic resonance imaging versus computed tomography and plain film ..

Isolation of retinoic acid-repressed genes from P19 embryonal carcinoma cells

H Nakshatri, P Bouillet, P BhatNakshatri, P Chambon

Journal article  |  1996  |  Gene

A new mouse member of the Wnt gene family, mWnt-8, is expressed during early embryogenesis and is ectopically induced by retinoic acid

P Bouillet, M OuladAbdelghani, SJ Ward, S Bronner, P Chambon, P Dolle

Journal article  |  1996  |  Mechanisms of Development

The expression pattern of the mouse receptor tyrosine kinase gene MDK1 is conserved through evolution and requires Hoxa-2 for rhombomere-specific expression in mouse embryos

R Taneja, B Thisse, FM Rijli, C Thisse, P Bouillet, P Dolle, P Chambon

Journal article  |  1996  |  Developmental Biology

AP-2.2: A novel AP-2-related transcription factor induced by retinoic acid during differentiation of P19 embryonal carcinoma cells

M OuladAbdelghani, P Bouillet, C Chazaud, P Dolle, P Chambon

Journal article  |  1996  |  Experimental Cell Research

Restricted expression of a novel retinoic acid responsive gene during limb bud dorsoventral patterning and endochondral ossification

C Chazaud, P Bouillet, M OuladAbdelghani, P Dolle

Journal article  |  1996  |  Developmental Genetics

[Study of morphometric and anatomo-densitometric correlations of the normal pancreas. Apropos of 28 cases].

F Lachachi, P Bouillet, D Valleix, B Descottes, M Caix

Journal article  |  1996  |  Annales de Radiologie

The authors report morphometric mensurations from axial features on CT scan of twenty eight cases of normal pancreas. A review of ..

AP-2.2, a novel gene related to AP-2, is expressed in the forebrain, limbs and face during mouse embryogenesis

C Chazaud, M OuladAbdelghani, P Bouillet, D Decimo, P Chambon, P Dolle

Journal article  |  1996  |  Mechanisms of Development

MRI of paraganglioma of the filum terminale.

MP Boncoeur-Martel, A Lesort, JJ Moreau, F Labrousse, I Roche, P Bouillet, JL Pascaud, JP Dupuy

Journal article  |  1996  |  Journal of Computer Assisted Tomography

SEQUENCE AND EXPRESSION PATTERN OF THE STRA7 (GBX-2) HOMEOBOX-CONTAINING GENE INDUCED BY RETINOIC ACID IN P19 EMBRYONAL CARCINOMA-CELLS

P BOUILLET, C CHAZAUD, M OULADABDELGHANI, P DOLLE, P CHAMBON

Journal article  |  1995  |  Developmental Dynamics

COMPARATIVE EXPRESSION OF THE PSORIASIN (S100A7) AND S100C GENES IN BREAST-CARCINOMA AND COLOCALIZATION TO HUMAN-CHROMOSOME 1Q21-Q22

C MOOGLUTZ, P BOUILLET, CH REGNIER, C TOMASETTO, MG MATTEI, MP CHENARD, P ANGLARD, MC RIO, P BASSET

Journal article  |  1995  |  International Journal of Cancer

REEXPRESSION OF RETINOIC ACID RECEPTOR (RAR)GAMMA OR OVEREXPRESSION OF RAR-ALPHA OR RAR-BETA IN RAR-GAMMA-NULL F9 CELLS REVEALS A PARTIAL FUNCTIONAL REDUNDANCY BETWEEN THE 3 RAR TYPES

R TANEJA, P BOUILLET, JF BOYLAN, MP GAUB, B ROY, LJ GUDAS, P CHAMBON

Journal article  |  1995  |  Proceedings of the National Academy of Sciences

EFFICIENT CLONING OF CDNAS OF RETINOIC ACID-RESPONSIVE GENES IN P19 EMBRYONAL CARCINOMA-CELLS AND CHARACTERIZATION OF A NOVEL MOUSE GENE, STRA1 (MOUSE LERK-2/EPLG2)

P BOUILLET, M OULADABDELGHANI, S VICAIRE, JM GARNIER, B SCHUHBAUR, P DOLLE, P CHAMBON

Journal article  |  1995  |  Developmental Biology

Granulocytic sarcoma of the brain: CT and MRI appearances

MP Boncoeur-Martel, E Liozon, JL Pascaud, P Bouillet, AF Le Blanche, J Macedo, JP Dupuy

Journal article  |  1994  |  Revue d'Imagerie Medicale

[Pulmonary hemosiderosis. Hemodynamic or idiopathic origin? Diagnostic contribution of imaging and review of the literature].

AF Le Blanche, JL Pascaud, P Bouillet, JF Majoulet, T Provensol, S Gaillard

Journal article  |  1991  |  Journal de Radiologie

We report two cases of Pulmonary Hemosiderosis. The first patient (adult male) had an angiosarcoma of the left auricle and develop..

[Congenital anomaly of the inferior vena cava with hemiazygos continuation. Ultrasonic diagnosis].

AF Le Blanche, P Bouillet, S Gaillard

Journal article  |  1990  |  Annales de Radiologie

Congenital anomaly of the inferior vena cava with hemiazygos continuation: ultrasonic diagnosis. We report a case of agenesis of t..

[Gastric leiomyosarcoma. Contribution of imaging to the diagnosis. Report of 2 cases].

P Millant, A Maréchal, JF Majoulet, P Bouillet, F Montagne, J Rousseau

Journal article  |  1990  |  Annales de Radiologie

Leiomyosarcomas, are rare gastric tumors with a tendency for extraluminal growth. In relation to two new cases, the authors report..

[Radiologic aspect of benign pleural fibrous mesothelioma. Reports of 4 cases].

JF Majoulet, P Millant, P Bouillet, AF Le Blanche, S Gaillard

Journal article  |  1990  |  Annales de Radiologie

Solitary fibrous tumor or pleural fibroma is a rare tumor. It grows slowly and has a good prognosis after surgical resection. Pleu..

[Fractures of the sacrum caused by bone insufficiency].

P Bouillet, R Trèves, JL Pascaud, G Rondier, A Maréchal, J Rousseau

Journal article  |  1988  |  Annales de Radiologie

Digital substraction angiography in cervico-cerebro trunks

JP Dupuy, P Bouillet, E Meary, F Mailhes

Journal article  |  1984  |  Angeiologie