Marnie Blewitt

Hippocampal neurogenesis mediates sex-specific effects of social isolation and exercise on fear extinction in adolescence.

Katherine D Drummond, Michelle L Waring, Geoffrey J Faulkner, Marnie E Blewitt, Christina J Perry, Jee Hyun Kim

Journal article  |  2021  |  Neurobiol Stress

Impaired extinction of conditioned fear is associated with anxiety disorders. Common lifestyle factors, like isolation stress and ..

SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization

Alexandra D Gurzau, Christopher R Horne, Yee-Foong Mok, Megan Iminitoff, Tracy A Willson, Samuel N Young, Marnie E Blewitt, James M Murphy

Journal article  |  2021  |  BIOCHEMICAL JOURNAL

Structural maintenance of chromosomes flexible hinge domain-containing 1 (SMCHD1) is an epigenetic regulator that mediates gene ex..

A functional genetic screen identifies aurora kinase b as an essential regulator of Sox9-positive mouse embryonic lung progenitor cells

Casey Ah-Cann, Verena C Wimmer, Clare E Weeden, Claire Marceaux, Charity W Law, Laura Galvis, Caitlin E Filby, Joy Liu, Kelsey Breslin, Tracy Willson, Matthew E Ritchie, Marnie E Blewitt, Marie-Liesse Asselin-Labat

Journal article  |  2021  |  DEVELOPMENT

Development of a branching tree in the embryonic lung is crucial for the formation of a fully mature functional lung at birth. Sox..

NanoMethViz: an R/Bioconductor package for visualizing long-read methylation data

Shian Su, Quentin Gouil, Marnie Blewitt, Dianne Cook, Peter Hickey, Matthew Ritchie

Journal article  |  2021

Motivation A key benefit of long-read nanopore sequencing technology is the ability to detect modified DNA bases, such as 5-methyl..

RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells

Kirsteen M Tullett, Peck Szee Tan, Hae-Young Park, Ralf B Schittenhelm, Nicole Michael, Rong Li, Antonia N Policheni, Emily Gruber, Cheng Huang, Alex J Fulcher, Jillian C Danne, Peter E Czabotar, Linda M Wakim, Justine D Mintern, Georg Ramm, Kristen J Radford, Irina Caminschi, Meredith O'Keeffe, Jose A Villadangos, Mark D Wright, et al.

Journal article  |  2020  |  ELIFE

The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction o..

Smchd1 is a maternal effect gene required for genomic imprinting

Iromi Wanigasuriya, Quentin Gouil, Sarah A Kinkel, Andres Tapia del Fierro, Tamara Beck, Ellise A Roper, Kelsey Breslin, Jessica Stringer, Karla Hutt, Heather J Lee, Andrew Keniry, Matthew E Ritchie, Marnie E Blewitt

Journal article  |  2020  |  ELIFE

Genomic imprinting establishes parental allele-biased expression of a suite of mammalian genes based on parent-of-origin specific ..

Relating SMCHD1 structure to its function in epigenetic silencing

Alexandra D Gurzau, Marnie E Blewitt, Peter E Czabotar, James M Murphy, Richard W Birkinshaw

Journal article  |  2020  |  BIOCHEMICAL SOCIETY TRANSACTIONS

The structural maintenance of chromosomes hinge domain containing protein 1 (SMCHD1) is a large multidomain protein involved in ep..

Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues

Kelan Chen, Richard W Birkinshaw, Alexandra D Gurzau, Iromi Wanigasuriya, Ruoyun Wang, Megan Iminitoff, Jarrod J Sandow, Samuel N Young, Patrick J Hennessy, Tracy A Willson, Denise A Heckmann, Andrew Webb, Marnie E Blewitt, Peter E Czabotar, James M Murphy

Journal article  |  2020  |  SCIENCE SIGNALING

Structural maintenance of chromosomes flexible hinge domain containing 1 (SMCHD1) is an epigenetic regulator in which polymorphism..

Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal

Kevin X Lau, Elizabeth A Mason, Joshua Kie, David P De Souza, Joachim Kloehn, Dedreia Tull, Malcolm J McConville, Andrew Keniry, Tamara Beck, Marnie E Blewitt, Matthew E Ritchie, Shalin H Naik, Daniela Zalcenstein, Othmar Korn, Shian Su, Irene Gallego Romero, Catrina Spruce, Christopher L Baker, Tracy C McGarr, Christine A Wells, et al.

Journal article  |  2020  |  Nature Communications

Archetypal human pluripotent stem cells (hPSC) are widely considered to be equivalent in developmental status to mouse epiblast st..

Smchd1 is a maternal effect gene required for autosomal imprinting

Iromi Wanigasuriya, Quentin Gouil, Sarah Kinkel, Andrés Tapia del Fierro, Tamara Beck, Ellise EA Roper, Kelsey Breslin, Jessica Stringer, Karla Hutt, Heather Lee, Andrew Keniry, Matthew Ritchie, Marnie Blewitt

Journal article  |  2020

Genomic imprinting establishes parental allele-biased expression of a suite of mammalian genes based on parent-of-origin specific ..