Stephen Nutt

The interweaved signatures of common-gamma-chain cytokines across immunologic lineages.

Alev Baysoy, Kumba Seddu, Tamara Salloum, Caleb A Dawson, Juliana J Lee, Liang Yang, Shani Gal-Oz, Hadas Ner-Gaon, Julie Tellier, Alberto Millan, Alexander Sasse, Brian Brown, Lewis L Lanier, Tal Shay, Stephen Nutt, Daniel Dwyer, Christophe Benoist, undefined Immunological Genome Project Consortium

Journal article  |  2023  |  J Exp Med

"γc" cytokines are a family whose receptors share a "common-gamma-chain" signaling moiety, and play central roles in differentiati..

Making sense of plasma cell heterogeneity.

David M Tarlinton, Zhoujie Ding, Julie Tellier, Stephen L Nutt

Journal article  |  2023  |  Curr Opin Immunol

Plasma cells (PCs) are essential for the quality and longevity of protective immunity. The canonical humoral response to vaccinati..

An arrayed CRISPR screen of primary B cells reveals the essential elements of the antibody secretion pathway.

Stephanie Trezise, Isabella Y Kong, Edwin D Hawkins, Marco J Herold, Simon N Willis, Stephen L Nutt

Journal article  |  2023  |  Front Immunol

BACKGROUND: Humoral immunity depends on the differentiation of B cells into antibody secreting cells (ASCs). Excess or inappropria..

NAb-seq: an accurate, rapid, and cost-effective method for antibody long-read sequencing in hybridoma cell lines and single B cells

Hema Preethi Subas Satish, Kathleen Zeglinski, Rachel T Uren, Stephen L Nutt, Matthew E Ritchie, Quentin Gouil, Ruth M Kluck

Journal article  |  2022  |  MABS

Despite their common use in research, monoclonal antibodies are currently not systematically sequenced. This can lead to issues wi..

CIS controls the functional polarization of GM-CSF-derived macrophages

Shengbo Zhang, Jai Rautela, Naiara G Bediaga, Tatiana B Kolesnik, Yue You, Junli Nie, Laura F Dagley, Justin Bedo, Hanqing Wang, Li Sun, Robyn Sutherland, Elliot Surgenor, Nadia Iannarella, Rhys Allan, Fernando Souza-Fonseca-Guimaraes, Yi Xie, Qike Wang, Yuxia Zhang, Yuekang Xu, Stephen L Nutt, et al.

Journal article  |  2022  |  CELLULAR & MOLECULAR IMMUNOLOGY

The cytokine granulocyte-macrophage-colony stimulating factor (GM-CSF) possesses the capacity to differentiate monocytes into macr..

The secret to longevity, plasma cell style

Julie Tellier, Stephen L Nutt

Journal article  |  2022  |  NATURE IMMUNOLOGY

Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis.

Ashleigh R Poh, Megan O'Brien, David Chisanga, Hong He, David Baloyan, Jasmin Traichel, Christine Dijkstra, Michaël Chopin, Stephen Nutt, Lachlan Whitehead, Louis Boon, Ashleigh Parkin, Clifford Lowell, Marina Pajic, Wei Shi, Mehrdad Nikfarjam, Matthias Ernst

Journal article  |  2022  |  Cell Rep

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a low 5-year survival rate and is associated with poor respo..

c-Myb instructs both stemness and functional exhaustion of CD8( ) T cells during chronic infection

C Tsui, L Kretschmer, S Rapelius, SS Gabriel, D Chisanga, K Knoepper, DT Utzschneider, S Nussing, Y Liao, T Mason, SV Torres, SA Wilcox, K Kanev, S Jarosch, J Leube, SL Nutt, D Zehn, I Parish, W Kastenmueller, W Shi, et al.

Conference Proceedings  |  2022  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Osteoclasts and Macrophages-Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development.

Benjamin Tosun, Lena Ingeborg Wolff, Astrid Houben, Stephen Nutt, Christine Hartmann

Journal article  |  2022  |  J Bone Miner Res

The formation of the bone marrow cavity is a prerequisite for endochondral ossification. In reviews and textbooks, it is occasiona..

Generation of a CRISPR activationmouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance (vol 13, 4739, 2022)

Yexuan Deng, Sarah T Diepstraten, Margaret A Potts, Goknur Giner, Stephanie Trezise, Ashley P Ng, Gerry Healey, Serena R Kane, Amali Cooray, Kira Behrens, Amy Heidersbach, Andrew J Kueh, Martin Pal, Stephen Wilcox, Lin Tai, Warren S Alexander, Jane E Visvader, Stephen L Nutt, Andreas Strasser, Benjamin Haley, et al.

Journal article  |  2022  |  NATURE COMMUNICATIONS

In this article the affiliation details for Amy Heidersbach were incorrectly given as ‘School of Dentistry and Medical Sciences, C..