Gabrielle Belz

Type 2 Innate Lymphoid Cells Protect against Colorectal Cancer Progression and Predict Improved Patient Survival

Qiutong Huang, Nicolas Jacquelot, Adele Preaudet, Soroor Hediyeh-zadeh, Fernando Souza-Fonseca-Guimaraes, Andrew NJ McKenzie, Philip M Hansbro, Melissa J Davis, Lisa A Mielke, Tracy L Putoczki, Gabrielle T Belz

Journal article  |  2021  |  Cancers

Chronic inflammation of the gastrointestinal (GI) tract contributes to colorectal cancer (CRC) progression. While the role of adap..

Differences in pulmonary group 2 innate lymphoid cells are dependent on mouse age, sex and strain

Svenja Loering, Guy JM Cameron, Nirmal P Bhatt, Gabrielle T Belz, Paul S Foster, Philip M Hansbro, Malcolm R Starkey

Journal article  |  2021  |  Immunology and Cell Biology

Innate lymphoid cells (ILCs) are resident in the lung and are involved in both the maintenance of homeostasis and the pathogenesis..

Intestinal-derived ILCs migrating in lymph increase IFN gamma production in response to Salmonella Typhimurium infection

Verena Kastele, Johannes Mayer, Edward S Lee, Natalie Papazian, John J Cole, Vuk Cerovic, Gabrielle Belz, Michio Tomura, Gerard Eberl, Carl Goodyear, Rose A Maciewicz, Daniel Wall, Tom Cupedo, David R Withers, Simon Milling

Journal article  |  2021  |  Mucosal Immunology

Innate lymphoid cells (ILCs) are enriched in mucosae and have been described as tissue-resident. Interestingly, ILCs are also pres..

Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment

Takumi Kobayashi, Pui Yeng Lam, Hui Jiang, Karolina Bednarska, Renee Elyse Gloury, Valentine Murigneux, Joshua Tay, Nicolas Jacquelot, Rui Li, Zewen Kelvin Tuong, Graham R Leggatt, Maher K Gandhi, Michelle M Hill, Gabrielle T Belz, Shyuan Ngo, Axel Kallies, Stephen R Mattarollo

Journal article  |  2020  |  Blood

NK cells play critical roles in protection against haematological malignancies but can acquire a dysfunctional state, which limits..

Transcriptome dynamics of CD4( ) T cells during malaria maps gradual transit from effector to memory

Megan SF Soon, Hyun Jae Lee, Jessica A Engel, Jasmin Straube, Bryce S Thomas, Clara PS Pernold, Lachlan S Clarke, Pawat Laohamonthonkul, Rohit N Haldar, Cameron G Williams, Lianne IM Lansink, Marcela L Moreira, Michael Bramhall, Lambros T Koufariotis, Scott Wood, Xi Chen, Kylie R James, Tapio Lonnberg, Steven W Lane, Gabrielle T Belz, et al.

Journal article  |  2020  |  Nature Immunology

The dynamics of CD4+ T cell memory development remain to be examined at genome scale. In malaria-endemic regions, antimalarial che..

Systemic administration of IL-33 induces a population of circulating KLRG1(hi)type 2 innate lymphoid cells and inhibits type 1 innate immunity against multiple myeloma

Camille Guillerey, Kimberley Stannard, Jason Chen, Sophie Krumeich, Kim Miles, Kyohei Nakamura, Jessica Smith, Yuan Yu, Susanna Ng, Heidi Harjunpaa, Michele WL Teng, Christian Engwerda, Gabrielle T Belz, Mark J Smyth

Journal article  |  2020  |  Immunology & Cell Biology

Type 2 innate lymphoid cells (ILC2s) are important producers of type 2 cytokines whose role in hematological cancers remains uncle..

Impact of diet and the bacterial microbiome on the mucous barrier and immune disorders

Charlotte A Alemao, Kurtis F Budden, Henry M Gomez, Saima F Rehman, Jacqueline E Marshall, Shakti D Shukla, Chantal Donovan, Samuel C Forster, Ian A Yang, Simon Keely, Elizabeth R Mann, Emad M El Omar, Gabrielle T Belz, Philip M Hansbro

Journal article  |  2020  |  Allergy

Therapeutic ISCOMATRIX (TM) adjuvant vaccine elicits effective anti-tumor immunity in the TRAMP-C1 mouse model of prostate cancer

Adele M Barr, Anabel Silva, Sandro Prato, Gabrielle T Belz, Eugene Maraskovsky, Adriana Baz Morelli

Journal article  |  2020  |  Cancer Immunology Immunotherapy

Cancer vaccine development has proven challenging with the exception of some virally induced cancers for which prophylactic vaccin..

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

Hui Fern Koay, Shian Su, Daniela Amann-Zalcenstein, Stephen R Daley, Iain Comerford, Carly E Whyte, Igor E Konstantinov, Yves d'Udekem, Tracey Baldwin, Peter F Hickey, Stuart P Berzins, Jeffrey YW Mak, Axel Kallies, Zhenjun Chen, Simone Nussing, Katherine Kedzierska, Laura K Mackay, Shaun R McColl, Elissa K Deenick, David P Fairlie, et al.

Conference Proceedings  |  2020  |  JOURNAL OF IMMUNOLOGY

Membrane association of a model CD4( ) T-cell vaccine antigen confers enhanced yet incomplete protection against murid herpesvirus-4 infection

Joseph Yunis, Alec J Redwood, Gabrielle T Belz, Philip G Stevenson

Journal article  |  2020  |  Immunology and Cell Biology

Vaccination against γ-herpesviruses has proved difficult. CD4+ T cells are essential to contain infection, but how best to prime t..