profile icon
Prof

Axel Kallies

Professorial Fellow
Microbiology and Immunology
science & technology
life sciences & biomedicine
animals
immunology
mice
humans
cell differentiation
differentiation
expression
Axel Kallies's Profile Picture
Prof

Axel Kallies

 
Division
Medicine, Dentistry and Health Sciences
Axel Kallies's Profile Picture
Prof

Axel Kallies

 
Print
Axel's  Short Profile
 

Projects

Displaying the 9 most recent projects by Axel Kallies.

Project icon

Molecular regulators of adaptive immunity to overwhelming viral infections

2021 - 2023
Active
Project icon

UNDERSTANDING THE DYNAMIC REGULATION OF EXHAUSTED AND TISSUE-RESIDENT MEMORY T CELLS DIFFERENTIATION IN TUMORS

2020 - 2022
Active
Project icon

TRANSCRIPTIONAL AND METABOLIC REGULATION OF EFFECTOR AND MEMORY LYMPHOCYTE DIFFERENTIATION

I am an internationally recognized expert in the field of lymphocyte biology. My work has shed light on antibody production, T cell response..

2018 - 2023
Active
Project icon

MOLECULAR PATHWAYS THAT CONTROL DIFFERENTIATION AND FUNCTION OF TISSUE-RESIDENT MEMORY T CELLS

T cells residing in organs such as gut, liver or skin guard against infection and are critical for preventing tumour development. We found t..

2018 - 2021
Active
Project icon

PROTECTIVE MECHANISMS OF MAP KINASE PHOSPHATASE 5 IN ADIPOSE TISSUE FIBROSIS, HEPATIC STEATOSIS AND ATHEROSCLEROSIS

Obesity and associated complications such as diabetes, non-alcoholic fatty liver disease and atherosclerosis are a serious health burden. Re..

2018 - 2020
Completed
Project icon

COLLABORATIVE RESEARCH AND LICENCE AGREEMENT (KALLIES LAB) – WEHI - TO ALLOW TRANSFER OF MATERIALS TO THE UNIVERSITY OF MELBOURNE (LEX 31104/ TA 38954)

2017 - 2020
Completed
Project icon

REGULATION OF METABOLIC DYSFUNCTION AND EXHAUSTION OF VIRUS-SPECIFIC T CELLS DURING CHRONIC INFECTION

T cells control infections and cancer cells. During chronic infection or tumor development, however, loss of function of T cells prevents ef..

2017 - 2018
Completed
Project icon

MAINTENANCE OF REGULATORY T CELLS DURING INFLAMMATION AND TUMOR DEVELOPMENT BY IL-33

Regulatory T cells (Tregs) are required for preventing inflammation in tissues such as lung, fat and skin. We found recently, that the signa..

2017 - 2018
Completed
Project icon

TRANSCRIPTIONAL AND EPIGENETIC CONTROL OF CONVENTIONAL AND REGULATORY T CELL DIFFERENTIATION

2013 - 2018
Completed

9

Projects

Project Types

8

Research Grant

1

Research Contracts

Scholarly Works

Displaying the 10 most recent scholarly works by Axel Kallies.

Scholarly works icon

Sex-specific adipose tissue imprinting of regulatory T cells (vol 579,pg 581, 2020)

Ajithkumar Vasanthakumar, David Chisanga, Jonas Blume, Renee Gloury, Kara Britt, Darren C Henstridge, Yifan Zhan, Santiago Valle Torres, Sebastian Liene, Nicholas Collins, Enyuan Cao, Tom Sidwell, Chaoran Li, Raul German Spallanzani, Yang Liao, Paul A Beavis, Thomas Gebhardt, Natalie Trevaskis, Stephen L Nutt, Jeffrey D Zajac, et al.

Journal article  |  2021  |  Nature

Scholarly works icon

A new species of the genus Paranthrenella Strand, 1916 (Lepidoptera: Sesiidae) from China

Tiantian Yu, Lei Gao, Axel Kallies, Yutaka Arita, Min Wang

Journal article  |  2021  |  Zootaxa

A new clearwing moth, Paranthrenella cinnamoma sp. nov., is described from southern China. Adults and genitalia are illustrated, D..

Scholarly works icon

Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment

Takumi Kobayashi, Pui Yeng Lam, Hui Jiang, Karolina Bednarska, Renee Elyse Gloury, Valentine Murigneux, Joshua Tay, Nicolas Jacquelot, Rui Li, Zewen Kelvin Tuong, Graham R Leggatt, Maher K Gandhi, Michelle M Hill, Gabrielle T Belz, Shyuan Ngo, Axel Kallies, Stephen R Mattarollo

Journal article  |  2020  |  Blood

NK cells play critical roles in protection against haematological malignancies but can acquire a dysfunctional state, which limits..

Scholarly works icon

New and little-known sun-moth species from Australia (Lepidoptera, Castniidae)

Axel Kallies, Edward D Edwards, Andrew AE Williams

Journal article  |  2020  |  Zootaxa

In this study, we designate lectotypes and fix the identities of two Australian Castniidae species, Synemon sophia (White, 1841), ..

Scholarly works icon

BATF3 programs CD8( )T cell memory

Marco A Ataide, Karl Komander, Konrad Knoepper, Annika E Peters, Hao Wu, Sarah Eickhoff, Tea Gogishvili, Justus Weber, Anika Grafen, Axel Kallies, Natalio Garbi, Hermann Einsele, Michael Hudecek, Georg Gasteiger, Michael Hoelzel, Martin Vaeth, Wolfgang Kastenmueller

Journal article  |  2020  |  Nature Immunology

Scholarly works icon

CHARACTERIZATION OF DONOR AND RECIPIENT MYELOID CELLS FOLLOWING CONGENIC AND ALLOGENEIC LIVER TRANSPLANTATION

Sarah Dart, Amy Prosser, Wen Hua Huang, Liu Liu, Monalyssa Watson, Bastiaan de Boer, Gary Jeffrey, Axel Kallies, Michaela Lucas

Conference Proceedings  |  2020  |  TRANSPLANTATION

Scholarly works icon

CHARACTERIZATION OF DONOR AND RECIPIENT MYELOID CELLS FOLLOWING CONGENIC AND ALLOGENEIC LIVER TRANSPLANTATION

Sarah Dart, Amy Prosser, Wen Hua Huang, Liu Liu, Monalyssa Watson, Bastiaan de Boer, Gary Jeffrey, Axel Kallies, Michaela Lucas

Journal article  |  2020  |  Transplantation

Scholarly works icon

LIVER TISSUE-RESIDENT LYMPHOCYTES ARE SIGNIFICANTLY HETEROGENEOUS, AND THE ORIGINAL REPERTOIRE IS NOT RECREATED BY INFILTRATING RECIPIENT CELLS

Amy Prosser, Wen Hua Huang, Sarah Dart, Monalyssa Watson, Liu Liu, Bastiaan de Boer, Axel Kallies, Michaela Lucas

Journal article  |  2020  |  Transplantation

Scholarly works icon

RECIPIENT BONE MARROW TREG; MAJOR PLAYERS IN TRANSPLANT TOLERANCE

Amy Prosser, Wen Hua Huang, Sarah Dart, Monalyssa Watson, Liu Liu, Bastiaan de Boer, Axel Kallies, Michaela Lucas

Journal article  |  2020  |  Transplantation

Scholarly works icon

Methio "mine"! Cancer cells steal methionine and impair CD8 T-cell function

Patrick M Gubser, Axel Kallies

Journal article  |  2020  |  Immunology and Cell Biology

Tumor cells steal methionine from CD8 T cells. High expression of the methionine transporters SLC7A5 and SLC43A2 allows tumor cell..

200

Scholarly Works

Keyword Analysis

Immunology
Clinical Health (organs, Diseases and Abnormal Conditions)
Expanding Knowledge
Evolutionary Biology
Biochemistry and Cell Biology
Genetics
Flora, Fauna and Biodiversity
Medical Microbiology
Cardiovascular Medicine and Haematology
Oncology and Carcinogenesis

News

Displaying the 3 most recent news articles by Axel Kallies.

News icon

How severe viral infections overwhelm immune cells

Daniel Utzschneider, Axel Kallies, Sarah Gabriel

September 3, 2020
News icon

Finding the sex factor in immunity

Ajith Vasanthakumar, Axel Kallies

February 26, 2020
News icon

What malaria can tell us about ‘switching off’ diseases like HIV

Yang Liao, Diana Hansen, Axel Kallies, Wei Shi

November 21, 2019

3

News Articles

Credentials

Positions

Professorial Fellow

Microbiology and Immunology

Links