Iain Clarke

Kiss1 expression in the hypothalamic arcuate nucleus is lower in dairy cows of reduced fertility†.

Iain J Clarke, Charlotte B Reed, Chris R Burke, Qun Li, Susanne Meier

Journal article  |  2022  |  Biol Reprod

We tested the hypothesis that divergent genetic merit for fertility of dairy cows is due to aberrant reproductive neuroendocrine f..

Response to kisspeptin and gonadotropin-releasing hormone agonist administration in Holstein-Friesian dairy heifers with positive or negative genetic merit for fertility traits

HE Flay, CB Reed, B Kuhn-Sherlock, CVC Phyn, CR Burke, S Meier, IJ Clarke

Journal article  |  2022  |  JOURNAL OF DAIRY SCIENCE

Previous research has identified that Holstein-Friesian dairy heifers with positive (POS) genetic merit for fertility traits (Fert..

Onset of normal cycles in postpartum anovulatory dairy cattle treated with kisspeptin.

Chris R Burke, John R Roche, Robert P Millar, Iain J Clarke

Journal article  |  2022  |  Reprod Fertil

UNLABELLED: The efficacy of a long-acting synthetic derivative of kisspeptin (Kp) to initiate normal oestrous cycles was tested in..

Hexapeptides from mammalian inhibitory hormone hunt activate and inactivate nematode reproduction.

John E Hart, Sharad Mohan, Keith G Davies, Ben Ferneyhough, Iain J Clarke, John A Hunt, Steve D Shnyder, Christopher R Mundy, David R Howlett, Russell P Newton

Journal article  |  2022  |  PLoS One

BACKGROUND: Biopurification has been used to disclose an evolutionarily conserved inhibitory reproductive hormone involved in tiss..

Access to Shade Mitigate Heat Stress and Improves Growth Performance in Lambs During Summer

Aleena Joy, Frank R Dunshea, Brian J Leury, Iain J Clarke, Kristy DiGiacomo, Pragna Prathap, Minghao Zhang, Surinder S Chauhan

Journal article  |  2021  |  Journal of Animal Science

The objective of the present study was to investigate the effects of provision of shade on behavior, physiology, and growth of Mer..

275 Access to Shade Mitigate Heat Stress and Improves Growth Performance in Lambs During Summer

Aleena Joy, Frank R Dunshea, Brian J Leury, Iain J Clarke, Kristy DiGiacomo, Pragna Prathap, Minghao Zhang, Surinder S Chauhan

Journal article  |  2021  |  Journal of Animal Science

The objective of the present study was to investigate the effects of provision of shade on behavior, physiology, and growth of Mer..

The melanocortin pathway and energy homeostasis: From discovery to obesity therapy

Giles SH Yeo, Daniela Herrera Moro Chao, Anna-Maria Siegert, Zoe M Koerperich, Mark D Ericson, Stephanie E Simonds, Courtney M Larson, Serge Luquet, Iain Clarke, Shubh Sharma, Karine Clement, Michael A Cowley, Carrie Haskell-Luevano, Lex Van der Ploeg, Roger AH Adan

Journal article  |  2021  |  MOLECULAR METABOLISM

BACKGROUND: Over the past 20 years, insights from human and mouse genetics have illuminated the central role of the brain leptin-m..

Glucagon-like peptide-1 control of GnRH secretion in female sheep

Leila Arbabi, Qun Li, Belinda A Henry, Iain J Clarke

Journal article  |  2021  |  JOURNAL OF ENDOCRINOLOGY

The role of glucagon-like peptide-1 (GLP-1) on gonadotropin-releasing hormone (GnRH) secretion was investigated in ovariectomised ..

Comparative Assessment of Thermotolerance in Dorper and Second-Cross (Poll Dorset/Merino x Border Leicester) Lambs

Aleena Joy, Frank R Dunshea, Brian J Leury, Kristy DiGiacomo, Iain J Clarke, Minghao H Zhang, Archana Abhijith, Richard Osei-Amponsah, Surinder S Chauhan

Journal article  |  2020  |  ANIMALS

The objective of this study was to compare the thermotolerance of second-cross (SC; Poll Dorset × Merino × Border Leicester) and D..

Effect of sex and sex steroids on brown adipose tissue heat production in humans

John-Paul Fuller-Jackson, Aimee L Dordevic, Iain J Clarke, Belinda A Henry

Journal article  |  2020  |  EUROPEAN JOURNAL OF ENDOCRINOLOGY

OBJECTIVE: Retrospective studies suggest that women have more active brown adipose tissue (BAT) than men, but little is known of t..