Andre Mu

Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria.

Andre Mu, William P Klare, Sarah L Baines, CN Ignatius Pang, Romain Guérillot, Nichaela Harbison-Price, Nadia Keller, Jonathan Wilksch, Nguyen Thi Khanh Nhu, Minh-Duy Phan, Bernhard Keller, Brunda Nijagal, Dedreia Tull, Saravanan Dayalan, Hwa Huat Charlie Chua, Dominik Skoneczny, Jason Koval, Abderrahman Hachani, Anup D Shah, Nitika Neha, et al.

Journal article  |  2023  |  Nat Commun

Even in the setting of optimal resuscitation in high-income countries severe sepsis and septic shock have a mortality of 20-40%, w..

Bacteriophage discovery to advance biotechnology and biotherapeutics

Andre Mu, Trevor D Lawley

Journal article  |  2023  |  NATURE REVIEWS MICROBIOLOGY

A global perspective on bacterial diversity in the terrestrial deep subsurface.

A Soares, A Edwards, D An, A Bagnoud, J Bradley, E Barnhart, M Bomberg, K Budwill, SM Caffrey, M Fields, J Gralnick, V Kadnikov, L Momper, M Osburn, A Mu, JW Moreau, D Moser, L Purkamo, SM Rassner, CS Sheik, et al.

Journal article  |  2023  |  Microbiology (Reading)

While recent efforts to catalogue Earth's microbial diversity have focused upon surface and marine habitats, 12-20 % of Earth's bi..

Chronic Leptin Deficiency Improves Tolerance of Physiological Damage and Host-Pathogen Cooperation during Yersinia pseudotuberculosis Infection.

Karina K Sanchez, Katia Troha, Andre Mu, Samuel E Redford, Justin L McCarville, Arianna Insenga, Sarah Stengel, Yujung Michelle Lee, Janelle S Ayres

Journal article  |  2022  |  Infect Immun

To combat infections, hosts employ a combination of antagonistic and cooperative defense strategies. The former refers to pathogen..

Gut microbiome signatures and host colorization with multidrug-resistant bacteria

Nicole S Isles, Andre Mu, Jason C Kwong, Benjamin P Howden, Timothy P Stinear

Journal article  |  2022  |  TRENDS IN MICROBIOLOGY

The human gut is host to a diverse range of microorganisms that offer protection against colonization by multidrug-resistant bacte..

Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection

Tania Wong Fok Lung, Daniel Charytonowicz, Kristin G Beaumont, Shivang S Shah, Shwetha H Sridhar, Claire L Gorrie, Andre Mu, Casey E Hofstaedter, David Varisco, Thomas H McConville, Marija Drikic, Brandon Fowler, Andreacarola Urso, Wei Shi, Dario Fucich, Medini K Annavajhala, Ibrahim N Khan, Irina Oussenko, Nancy Francoeur, Melissa L Smith, et al.

Journal article  |  2022  |  CELL METABOLISM

K. pneumoniae sequence type 258 (Kp ST258) is a major cause of healthcare-associated pneumonia. However, it remains unclear how it..

Adipose triglyceride lipase mediates lipolysis and lipid mobilization in response to iron-mediated negative energy balance

Alicia R Romero, Andre Mu, Janelle S Ayres

Journal article  |  2022  |  ISCIENCE

Maintenance of energy balance is essential for overall organismal health. Mammals have evolved complex regulatory mechanisms that ..

The Impact of Mouthwash on the Oropharyngeal Microbiota of Men Who Have Sex with Men: a Substudy of the OMEGA Trial

Erica L Plummer, Kate Maddaford, Gerald L Murray, Christopher K Fairley, Shivani Pasricha, Andre Mu, Catriona S Bradshaw, Deborah A Williamson, Eric PF Chow

Journal article  |  2022  |  MICROBIOLOGY SPECTRUM

Mouthwash is a commonly used product and has been proposed as an alternative intervention to prevent gonorrhea transmission. Howev..

Assessment of the microbiome during bacteriophage therapy in combination with systemic antibiotics to treat a case of staphylococcal device infection

Andre Mu, Daniel McDonald, Alan K Jarmusch, Cameron Martino, Caitriona Brennan, Mackenzie Bryant, Gregory C Humphrey, Julia Toronczak, Tara Schwartz, Dominic Nguyen, Gail Ackermann, Anthony D'Onofrio, Steffanie A Strathdee, Robert T Schooley, Pieter C Dorrestein, Rob Knight, Saima Aslam

Journal article  |  2021  |  MICROBIOME

BACKGROUND: Infectious bacterial diseases exhibiting increasing resistance to antibiotics are a serious global health issue. Bacte..

Microbiota control of maternal behavior regulates early postnatal growth of offspring

Yujung Michelle Lee, Andre Mu, Martina Wallace, Jivani M Gengatharan, Annalee J Furst, Lars Bode, Christian M Metallo, Janelle S Ayres

Journal article  |  2021  |  SCIENCE ADVANCES

Maternal behavior is necessary for optimal development and growth of offspring. The intestinal microbiota has emerged as a critica..