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Dr

Jeffrey Liddell

Research Fellow
Biochemistry and Pharmacology
science & technology
life sciences & biomedicine
animals
neurosciences & neurology
neurosciences
mice
humans
biochemistry & molecular biology
oxidative stress
Jeffrey Liddell's Profile Picture
Dr

Jeffrey Liddell

 
Division
Medicine, Dentistry and Health Sciences
Jeffrey Liddell's Profile Picture
Dr

Jeffrey Liddell

 
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Jeffrey's  Short Profile
 

Projects

Displaying the 9 most recent projects by Jeffrey Liddell.

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The neurotoxic consequences of glial iron accumulation in MND

2019 - 2019
Completed
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Loss of copper regulation promotes Nrf2 deficiency and oxidative stress in neurodegeneration

2016 - 2016
Completed
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AGENTS TARGETING IRON IN THE BRAIN IN PARKINSON'S DISEASE

The impaired coordination and tremors experienced by the 64,000 Australians with Parkinson’s disease make managing life at work and home dif..

2014 - 2017
Completed
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AGENTS TARGETING IRON IN THE BRAIN IN PARKINSON'S DISEASE

The impaired coordination and tremors experienced by the 64,000 Australians with Parkinson’s disease make managing life at work and home dif..

2014 - 2017
Completed
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Induction of Nrf2 by neuroprotective CuII(atsm) in SOD1-G37R astrocytes

2014 - 2014
Completed
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CUBTSCS AS POTENTIAL THERAPEUTICS FOR NEURODEGENERATIVE DISEASE

Dr Liddell is a neuroscientist investigating potential therapeutic agents for the treatment of diseases of affecting the brain such as Alzhe..

2013 - 2017
Completed
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Investigating the cellular targests of therapeutic metal complexes for the treatment of Alzheimer's disease

2012 - 2013
Completed
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Defining impaired energy metabolism in motor neuron disease

2012 - 2012
Completed
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Involvement of energy impairment in TDP-43-related neurodegenerative diseases

2012 - 2012
Completed

9

Projects

Project Types

7

Research Grant

2

Internal Research Grant

Scholarly Works

Displaying the 10 most recent scholarly works by Jeffrey Liddell.

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Copper-ATSM as a Treatment for ALS: Support from Mutant SOD1 Models and Beyond

Sara Nikseresht, James BW Hilton, Kai Kysenius, Jeffrey R Liddell, Peter J Crouch

Journal article  |  2020  |  Life

The blood-brain barrier permeant, copper-containing compound, CuII(atsm), has successfully progressed from fundamental research ou..

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A versatile quantitative microdroplet elemental imaging method optimised for integration in biochemical workflows for low-volume samples

Kai Kysenius, Bence Paul, James B Hilton, Jeffrey R Liddell, Dominic J Hare, Peter J Crouch

Journal article  |  2019  |  Analytical and Bioanalytical Chemistry

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Cu-II(atsm) Attenuates Neuroinflammation

Xin Yi Choo, Jeffrey R Liddell, Mikko T Huuskonen, Alexandra Grubman, Diane Moujalled, Jessica Roberts, Kai Kysenius, Lauren Patten, Hazel Quek, Lotta E Oikari, Clare Duncan, Simon A James, Lachlan E McInnes, David J Hayne, Paul S Donnelly, Eveliina Pollari, Suvi Vahatalo, Katarina Lejavova, Mikko Kettunen, Tarja Malm, et al.

Journal article  |  2018  |  FRONTIERS IN NEUROSCIENCE

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Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

Moataz Abdalkader, Riikka Lampinen, Katja M Kanninen, Tarja M Malm, Jeffrey R Liddell

Journal article  |  2018  |  FRONTIERS IN NEUROSCIENCE

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Nexus between mitochondrial function, iron, copper and glutathione in Parkinson's disease

Jeffrey R Liddell, Anthony R White

Journal article  |  2018  |  NEUROCHEMISTRY INTERNATIONAL

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Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?

Jeffrey R Liddell

Journal article  |  2017  |  ANTIOXIDANTS

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TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

Diane Moujalled, Alexandra Grubman, Karla Acevedo, Shu Yang, Yazi D Ke, Donia M Moujalled, Clare Duncan, Aphrodite Caragounis, Nirma D Perera, Bradley J Turner, Mercedes Prudencio, Leonard Petrucelli, Ian Blair, Lars M Ittner, Peter J Crouch, Jeffrey R Liddell, Anthony R White

Journal article  |  2017  |  Human Molecular Genetics

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Adamantyl- and other polycyclic cage-based conjugates of desferrioxamine B (DFOB) for treating iron-mediated toxicity in cell models of Parkinson's disease

Thomas J Telfer, Jeffrey R Liddell, Clare Duncan, Anthony R White, Rachel Codd

Journal article  |  2017  |  Bioorganic & Medicinal Chemistry Letters

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Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture

Alexandra I Mot, Jeffrey R Liddell, Anthony R White, Peter J Crouch

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

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Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes

Jeffrey R Liddell, Sarka Lehtonen, Clare Duncan, Velta Keksa-Goldsteine, Anna-Liisa Levonen, Gundars Goldsteins, Tarja Malm, Anthony R White, Jari Koistinaho, Katja M Kanninen

Journal article  |  2016  |  JOURNAL OF NEUROINFLAMMATION

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Scholarly Works

Keyword Analysis

Neurosciences
Expanding Knowledge
Clinical Health (organs, Diseases and Abnormal Conditions)
Biochemistry and Cell Biology
Inorganic Chemistry
Clinical Sciences
Medical Biochemistry and Metabolomics
Other Health
Other Medical and Health Sciences
Human Pharmaceutical Products

Credentials

Positions

Research Fellow

Biochemistry and Pharmacology

Education

Doctor of Philosophy

Monash University

Links