Chad Bousman

Cognitive reserve attenuates age-related cognitive decline in the context of putatively accelerated brain ageing in schizophrenia-spectrum disorders.

Tamsyn E Van Rheenen, Vanessa Cropley, Birgitte Fagerlund, Cassandra Wannan, Jason Bruggemann, Rhoshel K Lenroot, Suresh Sundram, Cynthia Shannon Weickert, Thomas W Weickert, Andrew Zalesky, Chad A Bousman, Christos Pantelis

Journal article  |  2020  |  Psychological Medicine

BACKGROUND: In schizophrenia, relative stability in the magnitude of cognitive deficits across age and illness duration is inconsi..

The ubiquitin proteasome system and schizophrenia

Sandra Luza, Carlos M Opazo, Chad A Bousman, Christos Pantelis, Ashley I Bush, Ian P Everall

Journal article  |  2020  |  The Lancet Psychiatry

The ubiquitin-proteasome system is a master regulator of neural development and the maintenance of brain structure and function. I..

Pharmacogenetic Implications for Antidepressant Pharmacotherapy in Late-Life Depression: A Systematic Review of the Literature for Response, Pharmacokinetics and Adverse Drug Reactions

Victoria S Marshe, Farhana Islam, Malgorzata Maciukiewicz, Chad Bousman, Harris A Eyre, Helen Lavretsky, Benoit H Mulsant, Charles F Reynolds, Eric J Lenze, Daniel J Mueller

Journal article  |  2020  |  The American Journal of Geriatric Psychiatry

Affecting up to 15% of older adults, late-life depression (LLD) is characterized by the occurrence of depressive symptoms after th..

Impact of CYP2C19 genotype-predicted enzyme activity on hippocampal volume, anxiety, and depression.

Aisouda Savadlou, Aurina Arnatkeviciute, Jeggan Tiego, Ziarih Hawi, Mark A Bellgrove, Alex Fornito, Chad Bousman

Journal article  |  2020  |  Psychiatry Research

Cytochrome P450 C19 (CYP2C19) metabolizes exogenous and endogenous compounds. Although CYP2C19 is highly expressed in the liver, i..

Breast Cancer Survivor Symptoms: A Comparison of Physicians' Consultation Records and Nurse-Led Survivorship Care Plans.

Christina Kozul, Lesley Stafford, Ruth Little, Chad Bousman, Allan Park, Kerry Shanahan, G Bruce Mann

Journal article  |  2020  |  Clinical Journal of Oncology Nursing

BACKGROUND: Survivorship care plans (SCPs) have been used to address ongoing health problems associated with the diagnosis and tre..

Reply to Dawes et al.

Abdullah Al Maruf, Mikayla Fan, Paul D Arnold, Daniel J Mueller, Katherine Aitchison, Chad A Bousman

Journal article  |  2020  |  The Canadian Journal of Psychiatry

Use of antidepressants with pharmacogenetic prescribing guidelines in a 10-year depression cohort of adult primary care patients.

Chaten D Jessel, Sam Mostafa, Maria Potiriadis, Ian P Everall, Jane M Gunn, Chad A Bousman

Journal article  |  2020  |  Pharmacogenetics and Genomics

OBJECTIVES: To describe the usage patterns of antidepressants with published CYP2D6- and CYP2C19-based prescribing guidelines amon..

Reporting of clozapine-induced gastrointestinal hypomotility and factors associated with fatal outcomes in Canada: A pharmacovigilance database study.

Cecilia L Liu, Abdullah Al Maruf, Chad A Bousman

Journal article  |  2020  |  Psychiatry Research

Clozapine-induced gastrointestinal hypomotility (CIGH) is poorly understood and potentially life-threatening. Herein, we present t..

Engaging in building the educational support needed to deliver precision health in Canada.

Dave W Anderson, Chad A Bousman, Krista Chapman

Journal article  |  2020  |  Healthcare Management Forum

Canadian healthcare facilities are poised to benefit from the tools of precision health. To do so effectively, however, it is cruc..

Impact of CYP1A2, CYP2C19, and CYP2D6 genotype- and phenoconversion-predicted enzyme activity on clozapine exposure and symptom severity

Dorothea Lesche, Sam Mostafa, Ian Everall, Christos Pantelis, Chad A Bousman

Journal article  |  2020  |  The Pharmacogenomics Journal

Clozapine is an atypical antipsychotic metabolized by CYP1A2, CYP2D6, and CYP2C19 enzymes. Among 66 adult schizophrenia patients t..

"Black box'' pharmacogenetic decision-support tools in psychiatry

Chad A Bousman, Harris A Eyre

Journal article  |  2020  |  Brazilian Journal of Psychiatry

Pharmacogenetic Testing Options Relevant to Psychiatry in Canada

Abdullah Al Maruf, Mikayla Fan, Paul D Arnold, Daniel J Mueller, Katherine J Aitchison, Chad A Bousman

Journal article  |  2020  |  The Canadian Journal of Psychiatry

OBJECTIVE: To identify and assess pharmacogenetic testing options relevant to psychiatry in Canada. METHOD: Searches of published ..

Parenting x Brain Development interactions as predictors of adolescent depressive symptoms and well-being: Differential susceptibility or diathesis-stress?

Camille Deane, Nandita Vijayakumar, Nicholas B Allen, Orli Schwartz, Julian G Simmons, Chad A Bousman, Christos Pantelis, Sarah Whittle

Journal article  |  2020  |  Development and Psychopathology

It is unclear how individual differences in parenting and brain development interact to influence adolescent mental health outcome..

The Influence of Maternal Parenting Style on the Neural Correlates of Emotion Processing in Children

Elena Pozzi, Julian G Simmons, Chad A Bousman, Nandita Vijayakumar, Katherine O Bray, Orwa Dandash, Sally Richmond, Orli Schwartz, Marc Seal, Lisa Sheeber, Marie BH Yap, Nicholas B Allen, Sarah L Whittle

Journal article  |  2020  |  Journal of the American Academy of Child & Adolescent Psychiatry

OBJECTIVE: The importance of parenting in influencing mental health outcomes, particularly depression, during childhood and adoles..

Genetic associations with clozapine-induced myocarditis in patients with schizophrenia

Paul Lacaze, Kathlyn J Ronaldson, Eunice J Zhang, Ana Alfirevic, Hardik Shah, Leah Newman, Maya Strahl, Melissa Smith, Chad Bousman, Ben Francis, Andrew P Morris, Trevor Wilson, Fernando Rossello, David Powell, Vivien Vasic, Robert Sebra, John J McNeil, Munir Pirmohamed

Journal article  |  2020  |  Translational Psychiatry

Clozapine is the most effective antipsychotic drug for schizophrenia, yet it can cause life-threatening adverse drug reactions, in..

A Call for Clear and Consistent Communications Regarding the Role of Pharmacogenetics in Antidepressant Pharmacotherapy.

J Kevin Hicks, Jeffrey R Bishop, Roseann S Gammal, Katrin Sangkuhl, Chad A Bousman, J Steven Leeder, Adrián Llerena, Daniel J Mueller, Laura B Ramsey, Stuart A Scott, Todd C Skaar, Kelly E Caudle, Teri E Klein, Andrea Gaedigk

Journal article  |  2020  |  Clinical Pharmacology & Therapeutics

Genetic testing in psychiatry: State of the evidence

Chad A Bousman, Lisa C Brown, Ajeet B Singh, Harris A Eyre, Daniel J Mueller

Book Chapter  |  2020

The Impact of Childhood Adversity on Cognitive Development in Schizophrenia

Ruth Wells, Isabella Jacomb, Vaidy Swaminathan, Suresh Sundram, Danielle Weinberg, Jason Bruggemann, Vanessa Cropley, Rhoshel K Lenroot, Avril M Pereira, Andrew Zalesky, Chad Bousman, Christos Pantelis, Cynthia Shannon Weickert, Thomas W Weickert

Journal article  |  2020  |  Schizophrenia Bulletin

Childhood adversity, such as physical, sexual, and verbal abuse, as well as neglect and family conflict, is a risk factor for schi..

Consumer participation in personalized psychiatry

Harris A Eyre, Elisabeth RB Becker, Marissa S Blumenthal, Ajeet B Singh, Cyrus Raji, Arshya Vahabzadeh, Zoe Wainer, Chad Bousman

Book Chapter  |  2020

Protocol for Clozapine Rechallenge in a Case of Clozapine-Induced Myocarditis

G Shivakumar, N Thomas, M Sollychin, A Takacs, S Kolamunna, P Melgar, F Connally, C Neil, C Bousman, M Jayaram, C Pantelis

Journal article  |  2019  |  The Canadian Journal of Psychiatry

Kava for generalised anxiety disorder: A 16-week double-blind, randomised, placebo-controlled study

Jerome Sarris, Gerard J Byrne, Chad A Bousman, Lachlan Cribb, Karen M Savage, Oliver Holmes, Jenifer Murphy, Patricia Macdonald, Anika Short, Sonia Nazareth, Emma Jennings, Stuart Thomas, Edward Ogden, Suneel Chamoli, Andrew Scholey, Con Stough

Journal article  |  2019  |  Australian & New Zealand Journal of Psychiatry

OBJECTIVE: Previous randomised, double-blind, placebo-controlled studies have shown that Kava (a South Pacific medicinal plant) re..

International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic)

Takahiro Soda, Declan M McLoughlin, Scott R Clark, Leif Oltedal, Ute Kessler, Jan Haavik, Chad Bousman, Daniel J Smith, Miquel Bioque, Caitlin C Clements, Colleen Loo, Fidel Vila-Rodriguez, Alessandra Minelli, Brian J Mickey, Roumen Milev, Anna R Docherty, Julie Langan Martin, Eric D Achtyes, Volker Arolt, Ronny Redlich, et al.

Journal article  |  2019  |  European Archives of Psychiatry and Clinical Neuroscience

Increased peripheral inflammation in schizophrenia is associated with worse cognitive performance and related cortical thickness reductions

H North, J Bruggemann, V Cropley, V Swaminathan, S Sundram, R Lenroot, AM Pereira, A Zalesky, C Bousman, C Pantelis, T Weickert, C Shannon Weickert

Conference Proceedings  |  2019  |  European Neuropsychopharmacology

S-Adenosylmethionine (SAMe) monotherapy for depression: an 8-week double-blind, randomised, controlled trial

Jerome Sarris, Jenifer Murphy, Con Stough, David Mischoulon, Chad Bousman, Patricia MacDonald, Laura Adams, Sonia Nazareth, Georgina Oliver, Lachlan Cribb, Karen Savage, Ranjit Menon, Suneel Chamoli, Michael Berk, Chee H Ng, Gerard J Byrne

Journal article  |  2019  |  Psychopharmacology

RATIONALE: Dysregulation of the one carbon cycle is documented in depression. Thereby, S-adenosylmethionine (SAMe), a one-carbon c..

Adverse effect of catechol-O-methyltransferase (COMT) Val158Met met/met genotype in methamphetamine-related executive dysfunction

Mariana Cherner, Caitlin W-M Watson, Rowan Saloner, Laura E Halpin, Arpi Minassian, Sarah S Murray, Florin Vaida, Chad Bousman, Ian Everall, Igor Grant, Ronald J Ellis, Scott L Letendre, Cristian L Achim, Mariana Cherner, Erin E Morgan, Jared Young, Ian S Abramson, Clint Cushman, Florin Vaida, Ian S Abramson, et al.

Journal article  |  2019  |  Addictive Behaviors

INTRODUCTION: The Val allele of the Val158Met single-nucleotide polymorphism of the catechol-o-methyltransferase gene (COMT) confe..

Hippocampal subfields and visuospatial associative memory across stages of schizophrenia-spectrum disorder

Cassandra MJ Wannan, Vanessa L Cropley, M Mallar Chakravarty, Tamsyn E Van Rheenen, Sam Mancuso, Chad Bousman, Ian Everall, Patrick D McGorry, Christos Pantelis, Cali F Bartholomeusz

Journal article  |  2019  |  PSYCHOLOGICAL MEDICINE

BACKGROUND: While previous studies have identified relationships between hippocampal volumes and memory performance in schizophren..

EPA and DHA as markers of nutraceutical treatment response in major depressive disorder.

Kiki P van der Burg, Lachlan Cribb, Joseph Firth, Diana Karmacoska, David Mischoulon, Gerard J Byrne, Chad Bousman, Con Stough, Jenifer Murphy, Georgina Oliver, Michael Berk, Chee H Ng, Jerome Sarris

Journal article  |  2019  |  European Journal of Nutrition

PURPOSE: Depression clinical trials are increasingly studying biomarkers to predict and monitor response to treatment. Assessment ..

The schizophrenia genetics knowledgebase: a comprehensive update of findings from candidate gene studies

Chenxing Liu, Tetsufumi Kanazawa, Ye Tian, Suriati Mohamed Saini, Serafino Mancuso, Md Shaki Mostaid, Atsushi Takahashi, Dai Zhang, Fuquan Zhang, Hao Yu, Hyoung Doo Shin, Hyun Sub Cheong, Masashi Ikeda, Michiaki Kubo, Nakao Iwata, Sung-Il Woo, Weihua Yue, Yoichiro Kamatani, Yongyong Shi, Zhiqiang Li, et al.

Journal article  |  2019  |  Translational Psychiatry

Interaction between hypothalamic-pituitary-adrenal axis genetic variation and maternal behavior in the prediction of amygdala connectivity in children

Elena Pozzi, Chad A Bousman, Julian G Simmons, Nandita Vijayakumar, Orli Schwartz, Marc Seal, Marie BH Yap, Nicholas B Allen, Sarah L Whittle

Journal article  |  2019  |  NeuroImage

Exploring Heterogeneity on the Wisconsin Card Sorting Test in Schizophrenia Spectrum Disorders: A Cluster Analytical Investigation

Sean P Carruthers, Caroline T Gurvich, Denny Meyer, Chad Bousman, Ian P Everall, Erica Neill, Christos Pantelis, Philip J Sumner, Eric J Tan, Elizabeth HX Thomas, Tamsyn E Van Rheenen, Susan L Rossell

Journal article  |  2019  |  Journal of the International Neuropsychological Society

OBJECTIVES: The Wisconsin Card Sorting Test (WCST) is a complex measure of executive function that is frequently employed to inves..

Navigating the Labyrinth of Pharmacogenetic Testing: A Guide to Test Selection.

Chad A Bousman, Heather Zierhut, Daniel J Müller

Journal article  |  2019  |  Clinical Pharmacology & Therapeutics

Antidepressant pharmacogenetics in children and young adults: A systematic review.

Abdullah Al Maruf, Alexandra Greenslade, Paul D Arnold, Chad Bousman

Journal article  |  2019  |  Journal of Affective Disorders

OBJECTIVE: Antidepressants are frequently prescribed and are the first-line pharmacological treatments for psychiatric disorders i..

Evidence for Network-Based Cortical Thickness Reductions in Schizophrenia

Cassandra MJ Wannan, Vanessa L Cropley, M Mallar Chakravarty, Chad Bousman, Eleni P Ganella, Jason M Bruggemann, Thomas W Weickert, Cynthia Shannon Weickert, Ian Everall, Patrick McGorry, Dennis Velakoulis, Stephen J Wood, Cali F Bartholomeusz, Christos Pantelis, Andrew Zalesky

Journal article  |  2019  |  American Journal of Psychiatry

Blood and brain protein levels of ubiquitin-conjugating enzyme E2K (UBE2K) are elevated in individuals with schizophrenia

Hannah Meiklejohn, Md Shaki Mostaid, Sandra Luza, Serafino G Mancuso, Dali Kang, Sonny Atherton, Debora A Rothmond, Cynthia Shannon Weickert, Carlos M Opazo, Christos Pantelis, Ashley I Bush, Ian P Everall, Chad A Bousman

Journal article  |  2019  |  Journal of Psychiatric Research

CYP2D6 testing to guide risperidone and aripiprazole therapy.

Chad A Bousman

Journal article  |  2019  |  The Lancet Psychiatry

Interrogating the Evolutionary Paradox of Schizophrenia: A Novel Framework and Evidence Supporting Recent Negative Selection of Schizophrenia Risk Alleles

Chenxing Liu, Ian Everall, Christos Pantelis, Chad Bousman

Journal article  |  2019  |  Frontiers in Genetics

Moving pharmacoepigenetics tools for depression toward clinical use

Laura M Hack, Gabriel R Fries, Harris A Eyre, Chad A Bousman, Ajeet B Singh, Joao Quevedo, Vineeth P John, Bernhard T Baune, Boadie W Dunlop

Journal article  |  2019  |  Journal of Affective Disorders

Insula Functional Connectivity in Schizophrenia: Subregions, Gradients, and Symptoms

Ye Tian, Andrew Zalesky, Chad Bousman, Ian Everall, Christos Pantelis

Journal article  |  2019  |  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

BACKGROUND: The insular cortex is connected to a diverse network of cortical and subcortical areas. This study aimed to investigat..

HIPPOCAMPAL SUBFIELDS AND VISUOSPATIAL ASSOCIATIVE MEMORY ACROSS STAGES OF SCHIZOPHRENIA-SPECTRUM DISORDER

Cassandra Wannan, Vanessa Cropley, Mallar Chakravarty, Tamsyn Van Rheenen, Sam Mancuso, Chad Bousman, Ian Everall, Patrick McGorry, Christos Pantelis, Cali Bartholomeusz

Conference Proceedings  |  2019  |  Schizophrenia Bulletin

COGNITIVE RESERVE ATTENUATES AGE-RELATED COGNITIVE DECLINE IN THE CONTEXT OF ACCELERATED BRAIN AGEING IN SCHIZOPHRENIA-SPECTRUM DISORDERS: EVIDENCE FOR ACTIVE COMPENSATION

Tamsyn Van Rheenen, Vanessa Cropley, Birgitte Fagerlund, Cassandra Wannan, Jason Bruggemann, Rhoshel Lenroot, Suresh Sundram, Cynthia Shannon Weickert, Thomas Weickert, Andrew Zalesky, Chad Bousman, Christos Pantelis

Conference Proceedings  |  2019  |  SCHIZOPHRENIA BULLETIN

DISRUPTION IN HIPPOCAMPAL-PREFRONTAL WHITE MATTER PATHWAYS AND MEMORY PERFORMANCE ACROSS STAGES OF SCHIZOPHRENIA-SPECTRUM DISORDER

Cassandra Wannan, Cali Bartholomeusz, Mallar Chakravarty, Tamsyn Van Rheenen, Chad Bousman, Ian Everall, Patrick D McGorry, Christos Pantelis, Andrew Zalesky, Vanessa Cropley

Conference Proceedings  |  2019  |  Schizophrenia Bulletin

The effects of a muscarinic receptor 1 gene variant on executive and nonexecutive cognition in schizophrenia spectrum disorders

Sean P Carruthers, Vanessa Cropley, Chad Bousman, Ian P Everall, Erica Neill, Christos Pantelis, Philip J Sumner, Eric J Tan, Kiymet Bozaoglu, Elizabeth HX Thomas, Tamsyn E Van Rheenen, Caroline T Gurvich, Susan L Rossell

Journal article  |  2019  |  Psychiatry Research

Elevated ubiquitinated proteins in brain and blood of individuals with schizophrenia

Chad A Bousman, Sandra Luza, Serafino G Mancuso, Dali Kang, Carlos M Opazo, Md Shaki Mostaid, Vanessa Cropley, Patrick McGorry, Cynthia Shannon Weickert, Christos Pantelis, Ashley I Bush, Ian P Everall

Journal article  |  2019  |  SCIENTIFIC REPORTS

Nutraceuticals for major depressive disorder- more is not merrier: An 8-week double-blind, randomised, controlled trial

Jerome Sarris, Gerard J Byrne, Con Stough, Chad Bousman, David Mischoulon, Jenifer Murphy, Patricia Macdonald, Laura Adams, Sonia Nazareth, Georgina Oliver, Lachlan Cribb, Karen Savage, Ranjit Menon, Suneel Chamoli, Michael Berk, Chee H Ng

Journal article  |  2019  |  Journal of Affective Disorders

Investigation of peripheral complement factors across stages of psychosis

Liliana Laskaris, Andrew Zalesky, Cynthia Shannon Weickert, Maria A Di Biase, Gursharan Chana, Bernhard T Baune, Chad Bousman, Barnaby Nelson, Patrick McGorry, Ian Everall, Christos Pantelis, Vanessa Cropley

Journal article  |  2019  |  Schizophrenia Research

An Interleukin-1 beta (IL1B) haplotype linked with psychosis transition is associated with IL1B gene expression and brain structure

Md Shaki Mostaid, Stefanos Dimitrakopoulos, Cassandra Wannan, Vanessa Cropley, Cynthia Shannon Weickert, Jan P Everall, Christos Pantelis, Chad A Bousman

Journal article  |  2019  |  Schizophrenia Research

Systematic review and critical appraisal of child abuse measurement instruments

Suriati Mohamed Saini, Cassandra R Hoffmann, Christos Pantelis, Ian P Everall, Chad A Bousman

Journal article  |  2019  |  Psychiatry Research

PHARMACOGENETIC DECISION SUPPORT TOOLS AND SYMPTOM REMISSION: A META-ANALYSIS OF PROSPECTIVE RANDOMIZED CONTROLLED TRIALS IN MAJOR DEPRESSIVE DISORDER

Chad Bousman, Katarina Arandjelovic, Serafino Mancuso, Harris Eyre, Dunlop Boadie

Conference Proceedings  |  2019  |  European Neuropsychopharmacology

Towards the integration of pharmacogenetics in psychiatry: a minimum, evidence-based genetic testing panel.

Chad Bousman, Abdullah Al Maruf, Daniel J Müller

Journal article  |  2019  |  Current Opinion in Psychiatry

PURPOSE OF REVIEW: The implementation of pharmacogenetic testing in psychiatry is underway but is not yet standard protocol. Barri..

The role of depression pharmacogenetic decision support tools in shared decision making

Katarina Arandjelovic, Harris A Eyre, Eric Lenze, Ajeet B Singh, Michael Berk, Chad Bousman

Journal article  |  2019  |  Journal of Neural Transmission

ELEVATED PERIPHERAL EXPRESSION OF NEUREGULIN-1 (NRG1) MRNA ISOFORMS IN PATIENTS WITH TREATMENT-RESISTANT SCHIZOPHRENIA

Md Shaki Mostaid, Ting Ting Lee, Gursharan Chana, Suresh Sundram, Cynthia Shannon Weickert, Christos Pantelis, Ian Paul Everall, Chad Bousman

Conference Proceedings  |  2019  |  European Neuropsychopharmacology

INTERACTION EFFECTS OF CHILDHOOD ADVERSITY AND GLUTAMATERGIC POLYGENIC RISK SCORE ON BRAIN STRUCTURE AND COGNITION IN SCHIZOPHRENIA

Suriati Mohamed Saini, Sam Mancuso, Chenxing Liu, Md Shaki Mostaid, Vanessa Cropley, Tamsyn Van Rheenen, Ian Paul Everall, Chad Bousman, Christos Pantellis

Conference Proceedings  |  2019  |  European Neuropsychopharmacology

Implications of pharmacogenomics in depression pathophysiology and treatment

MP Forbes, P Jaksa, HA Eyre, C Bousman

Book Chapter  |  2019

Pharmacogenetic tests and depressive symptom remission: a meta-analysis of randomized controlled trials

Chad A Bousman, Katarina Arandjelovic, Serafino G Mancuso, Harris A Eyre, Boadie W Dunlop

Journal article  |  2019  |  Pharmacogenomics

UBIQUITINATED PROTEINS ARE ELEVATED IN THE BLOOD AND BRAIN OF INDIVIDUALS WITH SCHIZOPHRENIA

Chad Bousman, Sandra Luza, Serafino Mancuso, Dali Kang, Md Shaki Mostaid, Vanessa Cropley, Cynthia Shannon Weickert, Carlos Opazo, Christos Pantelis, Ashley Bush, Ian Paul Everall

Conference Proceedings  |  2019  |  European Neuropsychopharmacology

Towards pharmacogenetic-based treatment in psychiatry.

Chad A Bousman, Andreas Menke, Daniel J Müller

Journal article  |  2019  |  Journal of Neural Transmission

Genetic variations in the ADCK1 gene predict paliperidone palmitate efficacy in Han Chinese patients with schizophrenia.

Yun-Ai Su, Chad Bousman, Qian Li, Ji-Tao Li, Jing-Yu Lin, Tian-Mei Si

Journal article  |  2019  |  Journal of Neural Transmission

Genome-wide association study results have linked ADCK1 genetic variation with paliperidone efficacy in a European cohort. However..

Opportunities and challenges of implementation models of pharmacogenomics in clinical practice

JCW Liu, I Gorbovskaya, C Bousman, LC Brown, DJ Müller

Book Chapter  |  2019

INTERROGATING THE EVOLUTIONARY PARADOX OF SCHIZOPHRENIA: A NOVEL EVIDENCE FROM NEANDERTHALS AND DENISOVANS

Chenxing Liu, Christos Pantelis, Ian Paul Everall, Chad Bousman

Conference Proceedings  |  2019  |  European Neuropsychopharmacology

Decreased peripheral TNF alpha (TNF-alpha) mRNA expression in patients with treatment-resistant schizophrenia

Md Shaki Mostaid, Christos Pantelis, Ian P Everall, Chad A Bousman

Journal article  |  2018  |  Schizophrenia Research

Exploring the moderating effects of dopaminergic polymorphisms and childhood adversity on brain morphology in schizophrenia-spectrum disorders

Cassandra Hoffmann, Tamsyn E Van Rheenen, Serafino G Mancuso, Andrew Zalesky, Jason Bruggemann, Rhoshel K Lenroot, Suresh Sundram, Cynthia Shannon Weickert, Thomas W Weickert, Christos Pantelis, Vanessa Cropley, Chad A Bousman

Journal article  |  2018  |  PSYCHIATRY RESEARCH-NEUROIMAGING

Pharmacogenetic guidelines and decision support tools for depression treatment: application to late-life

Donald D Chang, Harris A Eyreeuro, Ryan Abbott, Michael Coudreaut, Bernhard T Baune, Jeffrey A Shaman, Helen Lavretsky, Eric J Lenze, David A Merrill, Ajeet B Singh, Benoit H Mulsant, Charles F Reynolds, Daniel J Mueller, Chad Bousman

Journal article  |  2018  |  Pharmacogenomics

The effects of a muscarinic receptor 1 gene variant on cortical thickness and surface area in schizophrenia

Sean P Carruthers, Caroline T Gurvich, Vanessa L Cropley, Christos Pantelis, Chad Bousman, Rhoshel K Lenroot, Jason M Bruggemann, Thomas Weickert, Susan L Rossell

Journal article  |  2018  |  Psychiatry Research: Neuroimaging

Pharmacogenetics in Psychiatry: A Companion, Rather Than Competitor, to Protocol-Based Care.

Chad A Bousman, Daniel J Müller

Journal article  |  2018  |  JAMA Psychiatry

FKBP5 Genetic Variation and Expression Among Depressed Individuals with Chronic Hepatitis C

Duy Pham Anh, Sern Wei Yeoh, Diana Lewis, Darren Wong, Gursharan Chana, Chad Bousman, Ting Ting Lee, Md Shaki Mostaid, Alex Holmes, Michael Saling, Ian Everall, Amanda Nicoll

Conference Proceedings  |  2018  |  HEPATOLOGY

Adjunctive S-adenosylmethionine (SAMe) in treating non-remittent major depressive disorder: An 8-week double-blind, randomized, controlled trial

Jerome Sarris, Gerard J Byrne, Chad Bousman, Con Stough, Jenifer Murphy, Patricia MacDonald, Laura Adams, Sonia Nazareth, Georgina Oliver, Lachlan Cribb, Karen Savage, Ranjit Menon, Suneel Chamoli, Michael Berk, Chee Ng, David Mischoulon

Journal article  |  2018  |  European Neuropsychopharmacology

Genotype, phenotype, and medication recommendation agreement among commercial pharmacogenetic-based decision support tools

Chad A Bousman, Boadie W Dunlop

Journal article  |  2018  |  The Pharmacogenomics Journal

Downregulation of plasma SELENBP1 protein in patients with recent-onset schizophrenia

Edith J Chau, Md Shaki Mostaid, Vanessa Cropley, Patrick McGorry, Christos Pantelis, Chad A Bousman, Ian P Everall

Journal article  |  2018  |  Progress in Neuro-Psychopharmacology and Biological Psychiatry

SimPEL: Simulation-based power estimation for sequencing studies of low-prevalence conditions

Lauren Mak, Minghao Li, Chen Cao, Paul Gordon, Maja Tarailo-Graovac, Chad Bousman, Pei Wang, Quan Long

Journal article  |  2018  |  Genetic Epidemiology

Mind the prevalence rate: overestimating the clinical utility of psychiatric diagnostic classifiers

Ahmad Abu-Akel, Chad Bousman, Efstratios Skafidas, Christos Pantelis

Journal article  |  2018  |  Psychological Medicine

Widespread Volumetric Reductions in Schizophrenia and Schizoaffective Patients Displaying Compromised Cognitive Abilities

Tamsyn E Van Rheenen, Vanessa Cropley, Andrew Zalesky, Chad Bousman, Ruth Wells, Jason Bruggemann, Suresh Sundram, Danielle Weinberg, Roshel K Lenroot, Avril Pereira, Cynthia Shannon Weickert, Thomas W Weickert, Christos Pantelis

Journal article  |  2018  |  SCHIZOPHRENIA BULLETIN

Genetic variation in cytokine genes and risk for transition to psychosis among individuals at ultra-high risk

Chad A Bousman, Tae Young Lee, Minah Kim, Junhee Lee, Md Shaki Mostaid, Minji Bang, Suk Kyoon An, Ian P Everall, Christos Pantelis, Jun Soo Kwon

Journal article  |  2018  |  Schizophrenia Research

Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group

S Kelly, N Jahanshad, A Zalesky, P Kochunov, I Agartz, C Alloza, OA Andreassen, C Arango, N Banaj, S Bouix, CA Bousman, RM Brouwer, J Bruggemann, J Bustillo, W Cahn, V Calhoun, D Cannon, V Carr, S Catts, J Chen, et al.

Journal article  |  2018  |  Molecular Psychiatry

FRONTOSTRIATAL CONNECTIVITY IN TREATMENT-RESISTANT SCHIZOPHRENIA: RELATIONSHIP TO POSITIVE SYMPTOMS AND COGNITIVE FLEXIBILITY

Vanessa Cropley, Eleni Ganella, Cassandra Wannan, Andrew Zalesky, Tamsyn Van Rheenen, Chad Bousman, Ian Everall, Alexander Fornito, Christos Pantelis

Conference Proceedings  |  2018  |  SCHIZOPHRENIA BULLETIN

Response to the article by Bousman and colleagues: 'Systematic evaluation of commercial pharmacogenetic testing in psychiatry' Reply

Chad A Bousman, Philip Jaksa, Christos Pantelis

Journal article  |  2018  |  Pharmacogenetics and Genomics

Neuregulin-1 (NRG1) polymorphisms linked with psychosis transition are associated with enlarged lateral ventricles and white matter disruption in schizophrenia

CA Bousman, V Cropley, P Klauser, JL Hess, A Pereira, R Idrizi, J Bruggemann, MS Mostaid, R Lenroot, TW Weickert, SJ Glatt, IP Everall, S Sundram, A Zalesky, CS Weickert, C Pantelis

Journal article  |  2018  |  Psychological Medicine

Risk and resilience brain networks in treatment-resistant schizophrenia

Eleni P Ganella, Caio Seguin, Cali F Bartholomeusz, Sarah Whittle, Chad Bousman, Cassandra MJ Wannan, Maria A Di Biase, Christina Phassouliotis, Ian Everall, Christos Pantelis, Andrew Zalesky

Journal article  |  2018  |  Schizophrenia Research

Pharmacogenetic Tests in Psychiatry

Chad Bousman, Josiah Allen, Harris A Eyre

Journal article  |  2018  |  American Journal of Psychiatry

Pharmacogenetic Decision Support Tools: A New Paradigm for Late-Life Depression?

Ryan Abbott, Donald D Chang, Harris A Eyre, Chad A Bousman, David A Merrill, Helen Lavretsky

Journal article  |  2018  |  The American Journal of Geriatric Psychiatry

Assessment of Placental Cortisol Pathway Gene Expression in Term Pregnant Women with Anxiety

Penelope M Sheehan, Chad Bousman, Angela Komiti, Fiona Judd, Louise Newman, Bruce Tonge, David Castle, Ian Everall

Journal article  |  2018  |  Neuropsychobiology

Erythrocyte polyunsaturated fatty acid composition is associated with depression and FADS genotype in Caucasians

Lachlan Cribb, Jenifer Murphy, Amy Froud, Georgina Oliver, Chad A Bousman, Chee H Ng, Jerome Sarris

Journal article  |  2018  |  Nutritional Neuroscience

Elevated peripheral expression of neuregulin-1 (NRG1) mRNA isoforms in clozapine-treated schizophrenia patients

Md Shaki Mostaid, Ting Ting Lee, Gursharan Chana, Suresh Sundram, Cynthia Shannon Weickert, Christos Pantelis, Ian Everall, Chad Bousman

Journal article  |  2017  |  Translational Psychiatry

White matter connectivity disruptions in early and chronic schizophrenia

MA Di Biase, VL Cropley, BT Baune, J Olver, GP Amminger, C Phassouliotis, C Bousman, PD McGorry, I Everall, C Pantelis, A Zalesky

Journal article  |  2017  |  Psychological Medicine

Peripheral Transcription of NRG-ErbB Pathway Genes Are Upregulated in Treatment-Resistant Schizophrenia

Md Shaki Mostaid, Ting Ting Lee, Gursharan Chana, Suresh Sundram, Cynthia Shannon Weickert, Christos Pantelis, Ian Everall, Chad Bousman

Journal article  |  2017  |  Frontiers in Psychiatry

Systematic evaluation of commercial pharmacogenetic testing in psychiatry: a focus on CYP2D6 and CYP2C19 allele coverage and results reporting

Chad A Bousman, Philip Jaksa, Christos Pantelis

Journal article  |  2017  |  Pharmacogenetics and Genomics

The Ubiquitin Proteasome System is Dysregulated in the Blood and Brain of Individuals With Schizophrenia

Chad Bousman

Conference Proceedings  |  2017  |  NEUROPSYCHOPHARMACOLOGY

Schizophrenia genetics in the genome-wide era: a review of Japanese studies

Tetsufumi Kanazawa, Chad A Bousman, Chenxing Liu, Ian P Everall

Journal article  |  2017  |  npj Schizophrenia

Meta-analysis supports GWAS-implicated link between GRM3 and schizophrenia risk

SM Saini, SG Mancuso, Md S Mostaid, C Liu, C Pantelis, IP Everall, CA Bousman

Journal article  |  2017  |  Translational Psychiatry

Functional brain networks in treatment-resistant schizophrenia

Eleni P Ganella, Cali F Bartholomeusz, Caio Seguin, Sarah Whittle, Chad Bousman, Christina Phassouliotis, Ian Everall, Christos Pantelis, Andrew Zalesky

Journal article  |  2017  |  Schizophrenia Research

Antidepressant Pharmacogenetics

Ajeet B Singh, Chad A Bousman

Journal article  |  2017  |  American Journal of Psychiatry

White Matter Disruptions in Schizophrenia Are Spatially Widespread and Topologically Converge on Brain Network Hubs

Paul Klauser, Simon T Baker, Vanessa L Cropley, Chad Bousman, Alex Fornito, Luca Cocchi, Janice M Fullerton, Paul Rasser, Ulrich Schall, Frans Henskens, Patricia T Michie, Carmel Loughland, Stanley V Catts, Bryan Mowry, Thomas W Weickert, Cynthia Shannon Weickert, Vaughan Carr, Rhoshel Lenroot, Christos Pantelis, Andrew Zalesky

Journal article  |  2017  |  Schizophrenia Bulletin

Accelerated Gray and White Matter Deterioration With Age in Schizophrenia

Vanessa L Cropley, Paul Klauser, Rhoshel K Lenroot, Jason Bruggemann, Suresh Sundram, Chad Bousman, Avril Pereira, Maria A Di Biase, Thomas W Weickert, Cynthia Shannon Weickert, Christos Pantelis, Andrew Zalesky

Journal article  |  2017  |  American Journal of Psychiatry

Pathway-wide association study identifies five shared pathways associated with schizophrenia in three ancestral distinct populations

C Liu, CA Bousman, C Pantelis, E Skafidas, D Zhang, W Yue, IP Everall

Journal article  |  2017  |  Translational Psychiatry

Antidepressant prescribing in the precision medicine era: a prescriber's primer on pharmacogenetic tools

Chad A Bousman, Malcolm Forbes, Mahesh Jayaram, Harris Eyre, Charles F Reynolds, Michael Berk, Malcolm Hopwood, Chee Ng

Journal article  |  2017  |  BMC PSYCHIATRY

Polygenic phenotypic plasticity moderates the effects of severe childhood abuse on depressive symptom severity in adulthood: A 5-year prospective cohort study

Chad A Bousman, Jane M Gunn, Maria Potiriadis, Ian P Everall

Journal article  |  2017  |  The World Journal of Biological Psychiatry

Meta-analysis reveals associations between genetic variation in the 5 ' and 3 ' regions of Neuregulin-1 and schizophrenia

MS Mostaid, SG Mancuso, C Liu, S Sundram, C Pantelis, IP Everall, CA Bousman

Journal article  |  2017  |  Translational Psychiatry

Concordance between actual and pharmacogenetic predicted desvenlafaxine dose needed to achieve remission in major depressive disorder: a 10-week open-label study

Chad A Bousman, Daniel J Mueller, Chee H Ng, Keith Byron, Michael Berk, Ajeet B Singh

Journal article  |  2017  |  Pharmacogenetics and Genomics

A Prospective Study of Serotonin and Norepinephrine Transporter Genes and the Response to Desvenlafaxine Over 8 Weeks in Major Depressive Disorder

CH Ng, C Bousman, DJ Smith, N Dowling, K Byron, J King, J Sarris

Journal article  |  2016  |  Pharmacopsychiatry

Neuregulin-1 and schizophrenia in the genome-wide association study era

Md Shaki Mostaid, David Lloyd, Benny Liberg, Suresh Sundram, Avril Pereira, Christos Pantelis, Tim Karl, Cynthia Shannon Weickert, Ian P Everall, Chad A Bousman

Journal article  |  2016  |  Neuroscience & Biobehavioral Reviews

The Brain-Derived neurotrophic Factor Val66Met Polymorphism Moderates the effects of childhood abuse on severity of Depressive symptoms in a Time-Dependent Manner

Caitlin Webb, Jane M Gunn, Maria Potiriadis, Ian P Everall, Chad A Bousman

Journal article  |  2016  |  Frontiers in Psychiatry

Early origins of mental disorder - risk factors in the perinatal and infant period

Louise Newman, Fiona Judd, Craig A Olsson, David Castle, Chad Bousman, Penelope Sheehan, Christos Pantelis, Jeffrey M Craig, Angela Komiti, Ian Everall

Journal article  |  2016  |  BMC PSYCHIATRY

Commercial pharmacogenetic-based decision-support tools in psychiatry

Chad A Bousman, Malcolm Hopwood

Journal article  |  2016  |  The Lancet Psychiatry

Genetic variation in the tryptophan hydroxylase 2 gene moderates depressive symptom trajectories and remission over 8 weeks of escitalopram treatment

Yun-Ai Su, Ji-Tao Li, Wen-Ji Dai, Xue-Mei Liao, Li-Cai Dong, Tian-Lan Lu, Chad Bousman, Tian-Mei Si

Journal article  |  2016  |  International Clinical Psychopharmacology

Predictors of depression and anxiety symptom trajectories in the 24 months following diagnosis of breast or gynaecologic cancer

Lesley Stafford, Angela Komiti, Chad Bousman, Fiona Judd, Penny Gibson, G Bruce Mann, Michael Quinn

Journal article  |  2016  |  The Breast

Intensive residential treatment for obsessive-compulsive disorder: Outcomes and predictors of patient adherence to cognitive behavioural therapy

Nathan Dowling, Neil Thomas, Scott Blair-West, Chad Bousman, Keong Yap, Deidre J Smith, Chee H Ng

Journal article  |  2016  |  Journal of Obsessive-Compulsive and Related Disorders

The effect of a muscarinic receptor 1 gene variant on grey matter volume in schizophrenia

Vanessa L Cropley, Elizabeth Scarr, Alex Fornito, Paul Klauser, Chad A Bousman, Rodney Scott, Murray J Cairns, Paul A Tooney, Christos Pantelis, Brian Dean

Journal article  |  2015  |  Psychiatry Research: Neuroimaging

Kava for the treatment of generalised anxiety disorder (K-GAD): study protocol for a randomised controlled trial

Karen M Savage, Con K Stough, Gerard J Byrne, Andrew Scholey, Chad Bousman, Jenifer Murphy, Patricia Macdonald, Chao Suo, Matthew Hughes, Stuart Thomas, Rolf Teschke, Chengguo Xing, Jerome Sarris

Journal article  |  2015  |  Trials

Effects of oxytocin and genetic variants on brain and behaviour: Implications for treatment in schizophrenia

Cali F Bartholomeusz, Eleni P Ganella, Izelle Labuschagne, Chad Bousman, Christos Pantelis

Journal article  |  2015  |  Schizophrenia Research

Inhibition of catechol-O-methyl transferase (COMT) by tolcapone restores reductions in microtubule-associated protein 2 (MAP2) and synaptophysin (SYP) following exposure of neuronal cells to neurotropic HIV

Ting Ting Lee, Gursharan Chana, Paul R Gorry, Anne Ellett, Chad A Bousman, Melissa J Churchill, Lachlan R Gray, Ian P Everall

Journal article  |  2015  |  JOURNAL OF NEUROVIROLOGY

Serotonin transporter polymorphism (5HTTLPR), severe childhood abuse and depressive symptom trajectories in adulthood

Timothy B Nguyen, Jane M Gunn, Maria Potiriadis, Ian P Everall, Chad A Bousman

Journal article  |  2015  |  BJPsych Open

Effects of COMT, DRD2, BDNF, and APOE Genotypic Variation on Treatment Efficacy and Cognitive Side Effects of Electroconvulsive Therapy

Chad A Bousman, Natalie Katalinic, Donel M Martin, Deidre J Smith, Anna Ingram, Nathan Dowling, Chee Ng, Colleen K Loo

Journal article  |  2015  |  The Journal of ECT

An adjunctive antidepressant nutraceutical combination in treating major depression: Study protocol, and clinical considerations

Jerome Sarris, Con Stough, Chad Bousman, Jenifer Murphy, Karen Savage, Deidre J Smith, Ranjit Menon, Suneel Chamoli, Georgina Oliver, Michael Berk, Gerard J Byrne, Chee Ng, David Mischoulon

Journal article  |  2015  |  Advances in Integrative Medicine

Effects of Persisting Emotional Impact from Child Abuse and Norepinephrine Transporter Genetic Variation on Antidepressant Efficacy in Major Depression: A Pilot Study

Ajeet Bhagat Singh, Chad A Bousman, Chee Hong Ng, Keith Byron, Michael Berk

Journal article  |  2015  |  Clinical Psychopharmacology and Neuroscience

Typologies of Positive Psychotic Symptoms in Methamphetamine Dependence

Chad A Bousman, Rebecca McKetin, Richard Burns, Steven Paul Woods, Erin E Morgan, J Hampton Atkinson, Ian P Everall, Igor Grant

Journal article  |  2015  |  The American Journal on Addictions

The impact of premorbid and current intellect in schizophrenia: cognitive, symptom, and functional outcomes

Ruth Wells, Vaidy Swaminathan, Suresh Sundram, Danielle Weinberg, Jason Bruggemann, Isabella Jacomb, Vanessa Cropley, Rhoshel Lenroot, Avril M Pereira, Andrew Zalesky, Chad Bousman, Christos Pantelis, Cynthia Shannon Weickert, Thomas W Weickert

Journal article  |  2015  |  npj Schizophrenia

Neuregulin-1 Loci Recently Associated with Psychosis Onset are Associated with Increased NRG1 mRNA and Lateral Ventricle Volume

Chad Bousman, Vanessa Cropley, Suresh Sundram, Avril Pereira, Rhoshel Lenroot, Jason Bruggemann, Elizabeth Scarr, Thomas Weickert, Andrew Zalesky, Ian Everall, Christos Pantelis, Cyndi Shannon Weickert

Conference Proceedings  |  2014  |  NEUROPSYCHOPHARMACOLOGY

Escitalopram Efficacy in Depression A Cross-Ethnicity Examination of the Serotonin Transporter Promoter Polymorphism

Chad A Bousman, Jerome Sarris, Eun-Soo Won, Hun-Soo Chang, Ajeet Singh, Hwa-Young Lee, Byung-Joo Ham, Chay-Hoon Tan, Min-Soo Lee, Chee H Ng

Journal article  |  2014  |  Journal of Clinical Psychopharmacology

Typologies of positive psychotic symptoms in methamphetamine dependence.

CA Bousman, R McKetin, R Burns, SP Woods, EE Morgan, JH Atkinson, IP Everall, I Grant, undefined the Translational Methamphetamine AIDS Research Center (TMARC) Group

Journal article  |  2014  |  American Journal on Addictions

Understanding methamphetamine associated psychotic (MAP) symptom typologies could aid in identifying individuals at risk of progre..

G-protein beta 3 subunit genetic variation moderates five-year depressive symptom trajectories of primary care attendees

Chad A Bousman, Maria Potiriadis, Ian P Everall, Jane M Gunn

Journal article  |  2014  |  JOURNAL OF AFFECTIVE DISORDERS

Biomarkers for psychosis onset: Promising candidates from the genome

C Bousman

Conference Proceedings  |  2014  |  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

BLOOD BRAIN BARRIER POLYMORPHISM PREDICTS ESCITALOPRAM DOSE NEEDED FOR REMISSION IN MAJOR DEPRESSION

Ajeet B Singh, Chad A Bousman, Chee H Ng, Keith Byron, Michael Berk

Conference Proceedings  |  2014  |  AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

HIGH-IMPACT CHILD ABUSE MAY PREDICT RISK OF ELEVATED SUICIDALITY DURING ANTIDEPRESSANT INITIATION

Ajeet B Singh, Chad A Bousman, Chee H Ng, Michael Berk

Conference Proceedings  |  2014  |  AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

PSYCHOMOTOR DEPRESSIVE SYMPTOMS MAY DIFFERENTIALLY RESPOND TO VENLAFAXINE, BUT NOREPINEPHRINE TRANSPORTER POLYMORPHISMS DO NOT APPEAR ASSOCIATED WITH DIFFERENTIAL SSRI TO SNRI EFFICACY IN MAJOR DEPRESSION

Ajeet B Singh, Chad A Bousman, Chee H Ng, Keith Byron, Michael Berk

Conference Proceedings  |  2014  |  AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Methylenetetrahydrofolate Reductase (MTHFR) Genetic Variation and Major Depressive Disorder Prognosis: A Five-Year Prospective Cohort Study of Primary Care Attendees

Chad A Bousman, Maria Potiriadis, Ian P Everall, Jane M Gunn

Journal article  |  2014  |  American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics

Construction of a genetic classifier for ASD using gene pathway analysis

G Chana, R Testa, P Gillett, D Williams, CA Bousman, D Zantomio, IP Everall, C Pantelis, E Skafidas

Book Chapter  |  2014

Effects of Neuregulin-1 Genetic Variation and Depression Symptom Severity on Longitudinal Patterns of Psychotic Symptoms in Primary Care Attendees

CA Bousman, M Potiriadis, IP Everall, JM Gunn

Journal article  |  2014  |  American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics

Pathogenesis of Mental Health Disorders in HIV

Gursharan Chana, Chad A Bousman, Ian P Everall

Book Chapter  |  2014

Antidepressant pharmacogenetics

Ajeet B Singh, Chad A Bousman, Chee Ng, Michael Berk

Journal article  |  2014  |  Current Opinion in Psychiatry

High impact child abuse may predict risk of elevated suicidality during antidepressant initiation

Ajeet B Singh, Chad A Bousman, Chee H Ng, Michael Berk

Journal article  |  2013  |  Australian and New Zealand Journal of Psychiatry

Kava for the Treatment of Generalized Anxiety Disorder RCT: Analysis of Adverse Reactions, Liver Function, Addiction, and Sexual Effects

J Sarris, C Stough, R Teschke, ZT Wahid, CA Bousman, G Murray, KM Savage, P Mouatt, C Ng, I Schweitzer

Journal article  |  2013  |  Phytotherapy Research: an international journal devoted to medical and scientific research on plants and plant products

Kava in the Treatment of Generalized Anxiety Disorder A Double-Blind, Randomized, Placebo-Controlled Study

Jerome Sarris, Con Stough, Chad A Bousman, Zahra T Wahid, Greg Murray, Rolf Teschke, Karen M Savage, Ashley Dowell, Chee Ng, Isaac Schweitzer

Journal article  |  2013  |  Journal of Clinical Psychopharmacology

Pharmacogenetic polymorphisms and response to escitalopram and venlafaxine over 8 weeks in major depression

Chee Ng, Jerome Sarris, Ajeet Singh, Chad Bousman, Keith Byron, Lai Huat Peh, Deidre Joy Smith, Chay Hoon Tan, Isaac Schweitzer

Journal article  |  2013  |  Human Psychopharmacology: Clinical and Experimental

Biomarker investigations related to pathophysiological pathways in schizophrenia and psychosis

Gursharan Chana, Chad A Bousman, Tammie T Money, Andrew Gibbons, Piers Gillett, Brian Dean, Ian P Everall

Journal article  |  2013  |  Frontiers in Cellular Neuroscience

Psychomotor depressive symptoms may differentially respond to venlafaxine

Ajeet B Singh, Chad A Bousman, Chee H Ng, Keith Byron, Michael Berk

Journal article  |  2013  |  International Clinical Psychopharmacology

Effects of NRG1 and DAOA genetic variation on transition to psychosis in individuals at ultra-high risk for psychosis

CA Bousman, AR Yung, C Pantelis, JA Ellis, RA Chavez, B Nelson, A Lin, SJ Wood, GP Amminger, D Velakoulis, PD McGorry, IP Everall, DL Foley

Journal article  |  2013  |  Translational Psychiatry

Negative Symptoms of Psychosis Correlate with Gene Expression of the Wnt/β-Catenin Signaling Pathway in Peripheral Blood.

Chad A Bousman, Stephen J Glatt, Sharon D Chandler, James Lohr, William S Kremen, Ming T Tsuang, Ian P Everall

Journal article  |  2013  |  Psychiatry J

Genes in the Wnt (wingless)/ β -catenin signaling pathway have been implicated in schizophrenia pathogenesis. No study has examine..

ABCB1 polymorphism predicts escitalopram dose needed for remission in major depression

AB Singh, CA Bousman, CH Ng, K Byron, M Berk

Journal article  |  2012  |  TRANSLATIONAL PSYCHIATRY

The acute effects of kava and oxazepam on anxiety, mood, neurocognition; and genetic correlates: a randomized, placebo-controlled, double-blind study

J Sarris, A Scholey, I Schweitzer, C Bousman, E LaPorte, C Ng, G Murray, C Stough

Journal article  |  2012  |  Human Psychopharmacology - Clinical and Experimental

Alpha-5 and-3 nicotinic receptor gene variants predict nicotine dependence but not cessation: Findings from the COMMIT cohort

Chad A Bousman, Cheryl Rivard, Jason Den Haese, Christine Ambrosone, Andrew Hyland

Journal article  |  2012  |  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Chronic Illness Histories of Adults Entering Treatment for Co-occurring Substance Abuse and Other Mental Health Disorders

Nicholas J Chesher, Chad A Bousman, Maiken Gale, Sonya B Norman, Elizabeth W Twamley, Robert K Heaton, Ian P Everall, Patricia A Judd

Journal article  |  2012  |  American Journal on Addictions

Oestrogen Alpha-Receptor Variant and Two-Year Memory Decline in Mid life Australian Women

Chad A Bousman, Cassandra Szoeke, Karren Chen, Lorraine Dennerstein, Victor W Henderson, Ian P Everall

Journal article  |  2012  |  Neuropsychobiology

Assessing Neuropsychological Performance in a Migrant Farm Working Colonia in Baja California, Mexico: A Feasibility Study

Chad A Bousman, Hugo Salgado, Terence Hendrix, Miguel Fraga, Mariana Cherner

Journal article  |  2011  |  Journal of Immigrant and Minority Health

Dopamine receptor D3 genetic polymorphism (rs6280TC) is associated with rates of cognitive impairment in methamphetamine-dependent men with HIV: preliminary findings

Saurabh Gupta, Chad A Bousman, Gursharan Chana, Mariana Cherner, Robert K Heaton, Reena Deutsch, Ronald J Ellis, Igor Grant, Ian P Everall

Journal article  |  2011  |  Journal of NeuroVirology

Characteristics of Homeless Youth Attending Two Different Youth Drop-In Centers

AM Shillington, CA Bousman, JD Clapp

Journal article  |  2011  |  Youth & Society

Methamphetamine-Associated Psychosis: A Model for Biomarker Discovery in Schizophrenia

Chad A Bousman, Stephen J Glatt, Ian P Everall, Ming T Tsuang

Book Chapter  |  2011

Formidable Challenges in the Search for Biomarkers of Psychiatric Disorders

CA Bousman, IP Everall

Journal article  |  2011  |  Metabolomics

Formidable Challenges in the Search for Biomarkers of Psychiatric Disorders

Chad A Bousman, Ian P Ian P. Everall

Journal article  |  2011  |  Journal of Postgenomics Drug & Biomarker Development

Homelessness and Neuropsychological Impairment Preliminary Analysis of Adults Entering Outpatient Psychiatric Treatment

Chad A Bousman, Elizabeth W Twamley, Lea Vella, Maiken Gale, Sonya B Norman, Patricia Judd, Ian P Everall, Robert K Heaton

Journal article  |  2010  |  Journal of Nervous and Mental Disease

Preliminary evidence of motor impairment among polysubstance 3,4-methylenedioxymethamphetamine users with intact neuropsychological functioning

Chad A Bousman, Mariana Cherner, Kristen T Emory, Daniel Barron, Patricia Grebenstein, J Hampton Atkinson, Robert K Heaton, Igor Grant

Journal article  |  2010  |  Journal of the International Neuropsychological Society

Positive Symptoms of Psychosis Correlate With Expression of Ubiquitin Proteasome Genes in Peripheral Blood

Chad A Bousman, Gursharan Chana, Stephen J Glatt, Sharon D Chandler, Todd May, James Lohr, William S Kremen, Ming T Tsuang, Ian P Everall

Journal article  |  2010  |  American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics

Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals

Erick T Tatro, Timothy B Nguyen, Chad A Bousman, Eliezer Masliah, Igor Grant, J Hampton Atkinson, Ian P Everall

Journal article  |  2010  |  Journal of NeuroVirology

Cytochrome P450-2D6 extensive metabolizers are more vulnerable to methamphetamine-associated neurocognitive impairment: Preliminary findings

Mariana Cherner, Chad Bousman, Ian Everall, Daniel Barron, Scott Letendre, Florin Vaida, J Hampton Atkinson, Robert Heaton, Igor Grant

Journal article  |  2010  |  Journal of the International Neuropsychological Society

Preliminary evidence of ethnic divergence in associations of putative genetic variants for methamphetamine dependence

Chad A Bousman, Stephen J Glatt, Mariana Cherner, J Hampton Atkinson, Igor Grant, Ming T Tsuang, Ian P Everall

Journal article  |  2010  |  Psychiatry Research

Formative Assessment of ARM-U: A Modular Intervention for Decreasing Risk Behaviors Among HIV-Positive and HIV-Negative Methamphetamine-Using MSM.

Richard S Garfein, Mitcheal Metzner, Jazmine Cuevas, Chad A Bousman, Thomas Patterson

Journal article  |  2010  |  Open AIDS J

BACKGROUND: Methamphetamine is a major contributor to HIV transmission among men who have sex with men (MSM). Recent studies show ..

Family History of Lung Cancer and Contemplation of Smoking Cessation

Chad A Bousman, Lisa Madlensky

Journal article  |  2010  |  Preventing chronic disease

Preliminary Evidence of Ubiquitin Proteasome System Dysregulation in Schizophrenia and Bipolar Disorder: Convergent Pathway Analysis Findings from Two Independent Samples

Chad A Bousman, Gursharan Chana, Stephen J Glatt, Sharon D Chandler, Ginger R Lucero, Erick Tatro, Todd May, James B Lohr, William S Kremen, Ming T Tsuang, Ian P Everall

Journal article  |  2010  |  American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics

COMT Val158Met Polymorphism, Executive Dysfunction, and Sexual Risk Behavior in the Context of HIV Infection and Methamphetamine Dependence.

CA Bousman, M Cherner, JH Atkinson, RK Heaton, I Grant, IP Everall, The Hnrc Group

Journal article  |  2010  |  Interdiscip Perspect Infect Dis

Catechol-O-methyltransferease (COMT) metabolizes prefrontal cortex dopamine (DA), a neurotransmitter involved in executive behavio..

HIV, Methamphetamine, and the Brain in the Era of Antiretroviral Treatment.

undefined Nguyen, A Bousman, GC Chana, undefined Tatro, IPE Everall

Book Chapter  |  2010

Impact of COMT Val158Met on executive functioning in the context of HIV and methamphetamine.

Chad A Bousman, Mariana Cherner, Stephen J Glatt, J Hampton Atkinson, Igor Grant, Ming T Tsuang, Ian P Everall

Journal article  |  2010  |  Neurobehavioral HIV Medicine

The catechol-O-methyltransferease (COMT) Val allele has been linked to executive dysfunction among healthy individuals. The nature..

Genetic Association Studies of Methamphetamine Use Disorders: A Systematic Review and Synthesis

Chad A Bousman, Stephen J Glatt, Ian P Everall, Ming T Tsuang

Journal article  |  2009  |  American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics

Negative mood and sexual behavior among non-monogamous men who have sex with men in the context of methamphetamine and HIV

CA Bousman, M Cherner, C Ake, S Letendre, JH Atkinson, TL Patterson, I Grant, IP Everall

Journal article  |  2009  |  Journal of Affective Disorders

Predictors of Weapon Carrying in Youth Attending Drop-in Centers

Elaine J Blumberg, Sandy Liles, Norma J Kelley, Melbourne F Hovell, Chad A Bousman, Audrey M Shillington, Ming Ji, John Clapp

Journal article  |  2009  |  American Journal of Health Behavior

Alternatively Spliced Genes as Biomarkers for Schizophrenia, Bipolar Disorder and Psychosis: A Blood-Based Spliceome-Profiling Exploratory Study.

SJ Glatt, SD Chandler, CA Bousman, G Chana, GR Lucero, E Tatro, T May, JB Lohr, WS Kremen, IP Everall, MT Tsuang

Journal article  |  2009  |  Current Pharmacogenomics

OBJECTIVE: Transcriptomic biomarkers of psychiatric diseases obtained from a query of peripheral tissues that are clinically acces..

Biomarker Discovery in Major Psychiatric Disorders: Approaches, Limitations, and Future Directions

A Bousman, G CHANA, undefined Tatro, undefined Glatt, undefined Tsuang, I EVERALL

Book Chapter  |  2009

Evaluation of OPRM1 variants in heroin dependence by family-based association testing and meta-analysis

Stephen J Glatt, Chad Bousman, Richard S Wang, Kenton K Murthy, Brinda K Rana, Jessica A Lasky-Su, Shao C Zhu, Ruimin Zhang, Jianhua Li, Bo Zhang, Jixiang Li, Michael J Lyons, Stephen V Faraone, Ming T Tsuang

Journal article  |  2007  |  Drug and Alcohol Dependence

Predictors of substance use among homeless youth in San Diego

CA Bousman, EJ Blumberg, AM Shillington, MF Hovell, M Ji, S Lehman, J Clapp

Journal article  |  2005  |  Addictive Behaviors

Holocene pollen from swamp, cave and hyrax dung deposits at Blydefontein (Kikvorsberge), Karoo, South Africa

L Scott, CB Bousman, M Nyakale

Journal article  |  2005  |  Quaternary International

Exploration of a genomic expression and pathway analysis approach to neurocognitive performance: preliminary findings

Chad Bousman

Journal article  |  Neurobehavioral HIV Medicine

Metabolomics of Psychotic Disorders

Tammie T Money Chad A Bousman

Journal article  |  Metabolomics