Matthias Reumann

High performance computing enabling exhaustive analysis of higher order single nucleotide polymorphism interaction in Genome Wide Association Studies

Benjamin Goudey, Mani Abedini, John L Hopper, Michael Inouye, Enes Makalic, Daniel F Schmidt, John Wagner, Zeyu Zhou, Justin Zobel, Matthias Reumann

Journal article  |  2015  |  HEALTH INFORMATION SCIENCE AND SYSTEMS

Genome-wide association studies (GWAS) are a common approach for systematic discovery of single nucleotide polymorphisms (SNPs) wh..

GENOME ASSEMBLY FRAMEWORK ON MASSIVELY PARALLEL, DISTRIBUTED MEMORY SUPERCOMPUTERS

Friedrich Menhorn, Matthias Reumann

Journal article  |  2013  |  BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK

Supercomputing Enabling Exhaustive Statistical Analysis of Genome Wide Association Study Data: Preliminary Results

Matthias Reumann, Enes Makalic, Benjamin W Goudey, Michael Inouye, Adrian Bickerstaffe, Minh Bui, Daniel J Park, Miroslaw K Kapuscinski, Daniel F Schmidt, Zeyu Zhou, Guoqi Qian, Justin Zobel, John Wagner, John L Hopper

Conference Proceedings  |  2012  |  2012 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)

Most published GWAS do not examine SNP interactions due to the high computational complexity of computing p-values for the interac..

Performance of Hybrid Programming Models for Multiscale Cardiac Simulations: Preparing for Petascale Computation

Bernard J Pope, Blake G Fitch, Michael C Pitman, John J Rice, Matthias Reumann

Journal article  |  2011  |  IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Future multiscale and multiphysics models that support research into human disease, translational medical science, and treatment c..

Design of Multiple Sequence Alignment Algorithms on Parallel, Distributed Memory Supercomputers

Philip C Church, Andrzej Goscinski, Kathryn Holt, Michael Inouye, Amol Ghoting, Konstantin Makarychev, Matthias Reumann

Conference Proceedings  |  2011  |  2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)

The challenge of comparing two or more genomes that have undergone recombination and substantial amounts of segmental loss and gai..

Precision Medicine: Dawn of Supercomputing in ‘omics Research

M Reumann, KE Holt, M Inouye, T Stinear, B Goudey, G Abraham, Q WANG, F Shi, A Kowalczyk, A Pearce, A Isaac, BJ Pope, H Butzkueven, J Wagner, S Moore, M Downton, PC Church, SJ Turner, J Field, M Southey, et al.

Conference Proceedings  |  2011

Petascale Computation Performance of Lightweight Multiscale Cardiac Models using Hybrid Programming Models

Bernard J Pope, Blake G Fitch, Michael C Pitman, John J Rice, Matthias Reumann

Conference Proceedings  |  2011  |  2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)

Future multiscale and multiphysics models must use the power of high performance computing (HPC) systems to enable research into h..

Orthogonal recursive bisection as data decomposition strategy for massively parallel cardiac simulations

Matthias Reumann, Blake G Fitch, Aleksandr Rayshubskiy, Michael C Pitman, John J Rice

Journal article  |  2011  |  BIOMEDIZINISCHE TECHNIK

We present the orthogonal recursive bisection algorithm that hierarchically segments the anatomical model structure into subvolume..