Simon Harrison

Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): a randomised, multicentre, open-label, phase 3 study

Michel Attal, Paul G Richardson, S Vincent Rajkumar, Jesus San-Miguel, Meral Beksac, Ivan Spicka, Xavier Leleu, Fredrik Schjesvold, Philippe Moreau, Meletios A Dimopoulos, Jeffrey Shang-Yi Huang, Jiri Minarik, Michele Cavo, H Miles Prince, Sandrine Mace, Kathryn P Corzo, Frank Campana, Solenn Le-Guennec, Franck Dubin, Kenneth C Anderson

Journal article  |  2019  |  The Lancet

Prolonged survival with the early use of a novel extracorporeal photopheresis regimen in patients with Sezary syndrome

Crystal Gao, Christopher McCormack, Carrie van der Weyden, Michelle S Goh, Belinda A Campbell, Robert Twigger, Odette Buelens, Simon J Harrison, Christine Khoo, Stephen Lade, H Miles Prince

Journal article  |  2019  |  Blood

Extracorporeal photopheresis (ECP) has demonstrated therapeutic benefit in patients with Sézary syndrome (SS) and erythrodermic my..

A Phase 1, First-in-Human Study of AMG 176, a Selective MCL-1 Inhibitor, in Patients With Relapsed or Refractory Multiple Myeloma

Andrew Spencer, Aaron Seth Rosenberg, Andrzej Jakubowiak, Noopur Raje, Manik Chatterjee, Suzanne Trudel, Nizar J Bahlis, David S Siegel, Stefan Wilop, Simon J Harrison, Murthy NagaKrishna, Shyeilla Dhuria, Antreas Hindoyan, Zach McIver, Haby Henary, Phuong Khanh Morrow, Andrew Roberts

Conference Proceedings  |  2019  |  Clinical Lymphoma Myeloma and Leukemia

Carfilzomib, Thalidomide and Dexa-methasone (KTd) is safe and effective in RRMM: interim analysis of the single arm, multicentre phase II ALLG MM018/AMN002 study

Slavisa Ninkovic, Wee Joo Chng, Simon J Harrison, Nick Murphy, Jae Hoon Lee, Jane Estell, Noemi Horvath, Richard Eek, Bradley Augustson, Akash Kalro, Rajeev Rajagopal, Kihyun Kim, Soo-Mee Bang, Shang-Yi Huang, Belinda Butcher, Brian Durie, Peter Mollee, Hang Quach

Conference Proceedings  |  2019  |  Clinical Lymphoma Myeloma and Leukemia

A Phase 3 Study of Venetoclax or Placebo in Combination with Bortezomib and Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma

Shaji Kumar, Simon J Harrison, Michele Cavo, Javier De La Rubia, Rakesh Popat, Cristina J Gasparetto, Vania Hungria, Hans J Salwender, Kenshi Suzuki, Inho Kim, Elizabeth Punnoose, Wan-Jen Hong, Kevin J Freise, Anjla Sood, Muhammad Jalaluddin, Jeremy Ross, James E Ward, Paulo Maciag, Philippe Moreau

Conference Proceedings  |  2019  |  Clinical Lymphoma Myeloma and Leukemia

Cell surface glucose-regulated protein 78 (GRP78) is upregulated in plasma cells of patients with multiple myeloma compared to monoclonal gammopathy of uncertain significance

Slavisa Ninkovic, Lenny Straszkowski, Anupa Dey, Constantine Tam, Harshal Nandurkar, Simon J Harrison, Louise Purton, Hang Quach

Conference Proceedings  |  2019  |  Clinical Lymphoma Myeloma and Leukemia

Pacific Islanders with multiple myeloma are younger and have inferior survival when compared to other ethnicities: a study from the Australian and New Zealand Myeloma and Related Diseases Registry (MRDR)

Hilary Blacklock, Elizabeth Moore, Cameron Wellard, Simon J Harrison, P Joy Ho, Jay Hocking, Zoe McQuilten, Peter Mollee, Hang Quach, Ruth Spearing, Erica Wood, Andrew Spencer

Conference Proceedings  |  2019  |  Clinical Lymphoma Myeloma and Leukemia

Efficacy of isatuximab/pomalidomide/dexamethasone in relapsed/refractory multiple myeloma: ICARIA-MM high-risk cytogenetics subgroup analysis

Simon J Harrison, Paul G Richardson, Adrian Alegre, David Simpson, Ming Chung Wang, Andrew Spencer, Sossana Delimpasi, Cyrille Hulin, Kazutaka Sunami, Thierry Facon, Philip Vlummens, Kwee Yong, Frank Campana, Marlene Inchauspe, Sandrine Mace, Marie-Laure Risse, Helgi van de Velde, Michel Attal

Conference Proceedings  |  2019  |  Clinical Lymphoma Myeloma and Leukemia

Effect of isatuximab plus pomalidomide/dexamethasone on renal impairment in relapsed/refractory multiple myeloma: ICARIA-MM study subgroup analysis

Meletios A Dimopoulos, Xavier Leleu, Philippe Moreau, Michel Attal, Paul G Richardson, Anna Marina Liberati, Simon J Harrison, H Miles Prince, Enrique M Ocio, Sylvie Assadourian, Frank Campana, Laure Malinge, Helgi van de Velde, Kwee Yong

Conference Proceedings  |  2019  |  Clinical Lymphoma Myeloma and Leukemia

Time from autologous to allogeneic hematopoietic stem cell transplantation impacts post-transplant outcomes in multiple myeloma.

Salvatore Fiorenza, David Routledge, Jenny Collins, Michael Shipton, Simon Harrison, Ashish Bajel, James Cavet, Eleni Tholouli, Jordan Gauthier, David Ritchie

Journal article  |  2019  |  Bone Marrow Transplantation

FDG-PET/CT in managing infection in patients with hematological malignancy: clinician knowledge and experience in Australia

Abby P Douglas, Karin A Thursky, Leon J Worth, Simon James Harrison, Rod John Hicks, Monica A Slavin

Journal article  |  2019  |  Leukemia & Lymphoma

PET/CT is useful for investigation of neutropenic fever (NF) and potential invasive fungal infection (IFI) in those with hematolog..

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study

Amit Khot, Natalie Brajanovski, Donald P Cameron, Nadine Hein, Kylee H Maclachlan, Elaine Sanij, John Lim, John Soong, Emma Link, Piers Blombery, Ella R Thompson, Andrew Fellowes, Karen E Sheppard, Grant A McArthur, Richard B Pearson, Ross D Hannan, Gretchen Poortinga, Simon J Harrison

Journal article  |  2019  |  Cancer Discovery

RNA polymerase I (Pol I) transcription of ribosomal RNA genes (rDNA) is tightly regulated downstream of oncogenic pathways, and it..

Renal Impairment at Diagnosis in Myeloma: Patient Characteristics, Treatment, and Impact on Outcomes. Results From the Australia and New Zealand Myeloma and Related Diseases Registry.

P Joy Ho, Elizabeth M Moore, Zoe K McQuilten, Cameron Wellard, Krystal Bergin, Bradley Augustson, Hilary Blacklock, Simon J Harrison, Noemi Horvath, Tracy King, Peter Mollee, Hang Quach, Christopher Reid, Brian Rosengarten, Patricia Walker, Erica M Wood, Andrew Spencer

Journal article  |  2019  |  Clinical Lymphoma Myeloma and Leukemia

BACKGROUND: Renal impairment (RI) is a common complication of multiple myeloma (MM) and remains a poor prognostic factor despite i..

Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Siltuximab in High-Risk Smoldering Multiple Myeloma

Timothy A Brighton, Amit Khot, Simon J Harrison, David Ghez, Brendan M Weiss, Andres Kirsch, Hila Magen, Mercedes Gironella, Albert Oriol, Matthew Streetly, Britte Kranenburg, Xiang Qin, Rajesh Bandekar, Peter Hu, Mary Guilfoyle, Ming Qi, Sepideh Nemat, Hartmut Goldschmidt

Journal article  |  2019  |  Clinical Cancer Research

The Use of Optimal Treatment for DLBCL Is Improving in All Age Groups and Is a Key Factor in Overall Survival, but Non-Clinical Factors Influence Treatment

Nicole Wong Doo, Victoria M White, Kara Martin, Julie K Bassett, H Miles Prince, Simon J Harrison, Michael Jefford, Ingrid Winship, Jeremy L Millar, Roger L Milne, John F Seymour, Graham G Giles

Journal article  |  2019  |  Cancers

INTRODUCTION: Diffuse large B cell lymphoma (DLBCL) is an aggressive form of non-Hodgkin lymphoma for which a cure is usually the ..

Access, knowledge and experience with fluorodeoxyglucose positron emission tomography/computed tomography in infection management: a survey of Australia and New Zealand infectious diseases physicians and microbiologists

Abby P Douglas, Karin A Thursky, Leon J Worth, Simon J Harrison, Rodney J Hicks, Monica A Slavin

Journal article  |  2019  |  Internal Medicine Journal

The pharmacokinetics and pharmacodynamics of busulfan when combined with melphalan as conditioning in adult autologous stem cell transplant recipients

Abbey Willcox, Eric Wong, Christa Nath, Brett Janson, Simon J Harrison, Rosemary Hoyt, Ashish Bajel, Peter Shaw, David Ritchie, Andrew Grigg

Journal article  |  2018  |  Annals of Hematology

Novel Combination Therapy Targeting rDNA Transcription and Histone Deacetylation Provides Effective Treatment for Multiple Myeloma, and Synergises in Bortezomib-Resistant MM

Kylee H Maclachlan, Andrew Cuddihy, Nadine Hein, Carleen Cullinane, Simon J Harrison, Ross Hannan, Gretchen Poortinga

Conference Proceedings  |  2018  |  Blood

Outcomes of Autologous Stem Cell Transplantation (ASCT) in Elderly Multiple Myeloma (MM) Patients Aged >= 65 Years: A Multi-Centre Australian Experience

Jeremy An Ke Er, David Routledge, Jennifer Hempton, Colin Wood, Trish Joyce, Simon J Harrison, Philip Campbell

Conference Proceedings  |  2018  |  Blood

Carfilzomib Thalidomide and Dexamethasone Is Safe and Effective in the Treatment of Relapsed/Refractory Multiple Myeloma: Preliminary Outcome from the Open Label Phase II ALLGMM018/AMN003 Study

Hang Quach, Simon J Harrison, Slavisa Ninkovic, Jane Estell, Noemi Horvath, Nick Murphy, Richard Eek, Bradley Augustson, Philip Campbell, Rajeev Rajagopal, Akash Kalro, Robyn Hemme, Belinda Butcher, Tracey Gerber, Peter Mollee, Brian GM Durie, Wee-Joo Chng

Conference Proceedings  |  2018  |  Blood

Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma

Nicholas A Gherardin, Liyen Loh, Lorenztino Admojo, Alexander J Davenport, Kelden Richardson, Amy Rogers, Phillip K Darcy, Misty R Jenkins, H Miles Prince, Simon J Harrison, Hang Quach, David P Fairlie, Katherine Kedzierska, James McCluskey, Adam P Uldrich, Paul J Neeson, David S Ritchie, Dale I Godfrey

Journal article  |  2018  |  Scientific Reports

Considerations for pre-transfusion immunohaematology testing in patients receiving the anti-CD38 monoclonal antibody daratumumab for the treatment of multiple myeloma

Hang Quach, Simon Benson, Helen Haysom, Anne-Marie Wilkes, Nicole Zacher, Merrole Cole-Sinclair, Henry Miles Prince, Peter Mollee, Andrew Spencer, Phoebe Joy Ho, Simon J Harrison, Cindy Lee, Bradley Augustson, James Daly

Journal article  |  2018  |  Internal Medicine Journal

A phase 1 clinical trial evaluating marizomib, pomalidomide and low-dose dexamethasone in relapsed and refractory multiple myeloma (NPI-0052-107): final study results

Andrew Spencer, Simon Harrison, Jeffrey Zonder, Ashraf Badros, Jacob Laubach, Krystal Bergin, Amit Khot, Todd Zimmerman, Dharminder Chauhan, Nancy Levin, Ann MacLaren, Steven D Reich, Mohit Trikha, Paul Richardson

Journal article  |  2018  |  British Journal of Haematology

"Real-world' Australian experience of pomalidomide for relapsed and refractory myeloma

Ashleigh Scott, Nicholas Weber, Campbell Tiley, Kerry Taylor, John Taper, Simon Harrison, Kah-Lok Chan, Richard Stark, Cindy Lee, Kirk Morris, P Joy Ho, Anthony Dodds, Sundra Ramanathan, Raj Ramakrishna, Anne-Marie Watson, Bradley Auguston, Fiona Kwok, Hang Quach, Pauline Warburton, Philip Rowlings, et al.

Journal article  |  2018  |  Leukemia & Lymphoma

Promising efficacy and acceptable safety of venetoclax plus bortezomib and dexamethasone in relapsed/refractory MM

Philippe Moreau, Asher Chanan-Khan, Andrew W Roberts, Amit B Agarwal, Thierry Facon, Shaji Kumar, Cyrille Touzeau, Elizabeth A Punnoose, Jaclyn Cordero, Wijith Munasinghe, Jia Jia, Ahmed Hamed Salem, Kevin J Freise, Joel D Leverson, Sari Heitner Enschede, Jeremy A Ross, Paulo C Maciag, Maria Verdugo, Simon J Harrison

Journal article  |  2017  |  Blood

The influence of unmet supportive care needs on anxiety and depression during cancer treatment and beyond: a longitudinal study of survivors of haematological cancers

Devesh Oberoi, Victoria M White, John F Seymour, H Miles Prince, Simon Harrison, Michael Jefford, Ingrid Winship, David Hill, Damien Bolton, Anne Kay, Jeremy Millar, Nicole Wong Doo, Graham Giles

Journal article  |  2017  |  Supportive Care in Cancer

Distress and unmet needs during treatment and quality of life in early cancer survivorship: A longitudinal study of haematological cancer patients

Devesh V Oberoi, Victoria M White, John F Seymour, H Miles Prince, Simon Harrison, Michael Jefford, Ingrid Winship, David J Hill, Damien Bolton, Jeremy Millar, Nicole Wong Doo, Anne Kay, Graham Giles

Journal article  |  2017  |  European Journal of Haematology

Predicting Risk of Infection in Patients with Newly Diagnosed Multiple Myeloma: Utility of Immune Profiling

Benjamin W Teh, Simon J Harrison, Cody Charles Allison, Monica A Slavin, Tim Spelman, Leon J Worth, Karin A Thursky, David Ritchie, Marc Pellegrini

Journal article  |  2017  |  Frontiers in Immunology

Vox Sanguinis International Forum on provision of granulocytes for transfusion and their clinical use: summary

S Morton, S Stanworth, M Lozano, SJ Harrison, FS Hong, P Dennington, Z McQuilten, N Worel, V Compernolle, JM Kutner, APH Yokoyama, S Nahirniak, M Germain, H Hume, N Robitaille, A Wilson, A Tinmouth, E Massey, C Boulat, G Woimant, et al.

Journal article  |  2017  |  Vox Sanguinis

Vox Sanguinis International Forum on provision of granulocytes for transfusion and their clinical use

SJ Harrison, FS Hong, P Dennington, Z McQuilten, N Worel, V Compernolle, JM Kutner, APH Yokoyama, S Nahirniak, M Germain, H Hume, N Robitaille, A Wilson, A Tinmouth, S Morton, S Stanworth, E Massey, C Boulat, G Woimant, P Tiberghien, et al.

Journal article  |  2017  |  Vox Sanguinis

Physical Activity Preferences for People Living With Multiple Myeloma A Qualitative Study

Melinda Craike, Kaye Hose, Kerry S Courneya, Simon J Harrison, Patricia M Livingston

Journal article  |  2017  |  Cancer Nursing

Bisphosphonate guidelines for treatment and prevention of myeloma bone disease

Oi Lin Lee, Noemi Horvath, Cindy Lee, Doug Joshua, Joy Ho, Jeff Szer, Hang Quach, Andrew Spencer, Simon Harrison, Peter Mollee, Andrew W Roberts, Dipti Talaulikar, Ross Brown, Bradley Augustson, Silvia Ling, Wilfrid Jaksic, John Gibson, Anna Kalff, Anna Johnston, Akash Kalro, et al.

Journal article  |  2017  |  Internal Medicine Journal

The course of anxiety, depression and unmet needs in survivors of diffuse large B cell lymphoma and multiple myeloma in the early survivorship period

Devesh Oberoi, Victoria White, John Seymour, H Miles Prince, Simon Harrison, Michael Jefford, Ingrid Winship, David Hill, Damien Bolton, Anne Kay, Jeremy Millar, Nicole Wong Doo, Graham Giles

Journal article  |  2017  |  Journal of Cancer Survivorship

Multiple myeloma of the spine

Arian Lasocki, Frank Gaillard, Simon J Harrison

Journal article  |  2017  |  The Neuroradiology Journal

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

Nadine Hein, Donald P Cameron, Katherine M Hannan, Nhu-Y N Nguyen, Chun Yew Fong, Jirawas Sornkom, Meaghan Wall, Megan Pavy, Carleen Cullinane, Jeannine Diesch, Jennifer R Devlin, Amee J George, Elaine Sanij, Jaclyn Quin, Gretchen Poortinga, Inge Verbrugge, Adele Baker, Denis Drygin, Simon J Harrison, James D Rozario, et al.

Journal article  |  2017  |  Blood

Upfront lower dose lenalidomide is less toxic and does not compromise efficacy for vulnerable patients with relapsed refractory multiple myeloma: final analysis of the phase II RevLite study

Hang Quach, Liam Fernyhough, Ross Henderson, Gillian Corbett, Bart Baker, Peter Browett, Hilary Blacklock, Cecily Forsyth, Craig Underhill, Paul Cannell, Judith Trotman, Annette Neylon, Simon Harrison, Emma Link, Arlene Swern, Linda Cowan, Meletios A Dimopoulos, H Miles Prince

Journal article  |  2017  |  British Journal of Haematology

Epidemiology of bloodstream infections in patients with myeloma receiving current era therapy

Benjamin W Teh, Simon J Harrison, Monica A Slavin, Leon J Worth

Journal article  |  2017  |  European Journal of Haematology

Treatment of patients with Waldenstrom macroglobulinaemia: clinical practice guidelines from the Myeloma Foundation of Australia Medical and Scientific Advisory Group

Dipti Talaulikar, Constantine S Tam, Douglas Joshua, Joy Phoebe Ho, Jeff Szer, Hang Quach, Andrew Spencer, Simon Harrison, Peter Mollee, Andrew W Roberts, Noemi Horvath, Cindy Lee, Andrew Zannettino, Ross Brown, Bradley Augustson, Wilfrid Jaksic, John Gibson, Anna Kalff, Anna Johnston, Judith Trotman, et al.

Journal article  |  2017  |  Internal Medicine Journal

Engraftment syndrome manifesting as acute brachial neuropathy following high-dose chemotherapy for management of plasma cell myeloma

Slavisa Ninkovic, Chan Y Cheah, Arian Lasocki, Simon James Harrison

Journal article  |  2016  |  Leukemia & Lymphoma

Infection risk with immunomodulatory and proteasome inhibitor-based therapies across treatment phases for multiple myeloma: A systematic review and meta-analysis

Benjamin W Teh, Simon J Harrison, Leon J Worth, Karin A Thursky, Monica A Slavin

Journal article  |  2016  |  European Journal of Cancer

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments

Edwin D Hawkins, Delfim Duarte, Olufolake Akinduro, Reema A Khorshed, Diana Passaro, Malgorzata Nowicka, Lenny Straszkowski, Mark K Scott, Steve Rothery, Nicola Ruivo, Katie Foster, Michaela Waibel, Ricky W Johnstone, Simon J Harrison, David A Westerman, Hang Quach, John Gribben, Mark D Robinson, Louise E Purton, Dominique Bonnet, et al.

Journal article  |  2016  |  Nature

Caregivers' information needs and their 'experiences of care' during treatment are associated with elevated anxiety and depression: a cross-sectional study of the caregivers of renal cancer survivors

Devesh V Oberoi, Vicki White, Michael Jefford, Graham G Giles, Damien Bolton, Ian Davis, Ingrid Winship, H Miles Prince, Jeremy Millar, Simon Harrison, Anne Kay, David Hill

Journal article  |  2016  |  Supportive Care in Cancer

Phase I Clinical Trial of Marizomib (NPI-0052) in Patients with Advanced Malignancies Including Multiple Myeloma: Study NPI-0052-102 Final Results

Simon J Harrison, Paul Mainwaring, Timothy Price, Michael J Millward, Peeter Padrik, Craig R Underhill, Paul K Cannell, Steven D Reich, Mohit Trikha, Andrew Spencer

Journal article  |  2016  |  Clinical Cancer Research

Spontaneous onset and transplant models of the Vk*MYC mouse show immunological sequelae comparable to human multiple myeloma

Rachel E Cooke, Nicholas A Gherardin, Simon J Harrison, Hang Quach, Dale I Godfrey, Miles Prince, Rachel Koldej, David S Ritchie

Journal article  |  2016  |  Journal of Translational Medicine

Marizomib irreversibly inhibits proteasome to overcome compensatory hyperactivation in multiple myeloma and solid tumour patients

Nancy Levin, Andrew Spencer, Simon J Harrison, Dharminder Chauhan, Francis J Burrows, Kenneth C Anderson, Steven D Reich, Paul G Richardson, Mohit Trikha

Journal article  |  2016  |  British Journal of Haematology

The Perspectives of Haematological Cancer Patients on Tissue Banking

Heidi Turon, Amy Waller, Tara Clinton-McHarg, Allison Boyes, Jennifer Fleming, Paula Marlton, Simon J Harrison, Rob Sanson-Fisher

Journal article  |  2016  |  Oncology and Therapy

Predicting the response of multiple myeloma to the proteasome inhibitor Bortezomib by evaluation of the unfolded protein response

N Nikesitch, C Tao, K Lai, M Killingsworth, S Bae, M Wang, S Harrison, TL Roberts, SCW Ling

Journal article  |  2016  |  Blood Cancer Journal

Aggressive and extramedullary plasma cell myeloma evade bone marrow flow cytometric minimal residual disease detection

Neil Came, Nguyen Vuong, David Westerman, Simon Harrison

Journal article  |  2016  |  British Journal of Haematology

Update and new approaches in the treatment of Castleman disease

Kah-Lok Chan, Stephen Lade, H Miles Prince, Simon J Harrison

Journal article  |  2016  |  Journal of Blood Medicine

Myeloma of the central nervous system - an ongoing conundrum!

Simon J Harrison, Andrew Spencer, Hang Quach

Journal article  |  2016  |  Leukemia & Lymphoma

Antiviral prophylaxis for varicella zoster virus infections in patients with myeloma in the era of novel therapies

Benjamin W Teh, Simon J Harrison, Leon J Worth, Monica A Slavin

Journal article  |  2016  |  Leukemia & Lymphoma

Global measures of peripheral blood-derived DNA methylation as a risk factor in the development of mature B-cell neoplasms

Nicole Wong Doo, Enes Makalic, JiHoon E Joo, Claire M Vajdic, Daniel F Schmidt, Ee Ming Wong, Chol-Hee Jung, Gianluca Severi, Daniel J Park, Jessica Chung, Laura Baglietto, Henry Miles Prince, John F Seymour, Constantine Tam, John L Hopper, Dallas R English, Roger L Milne, Simon J Harrison, Melissa C Southey, Graham G Giles

Journal article  |  2016  |  Epigenomics

Risks, severity and timing of infections in patients with multiple myeloma: a longitudinal cohort study in the era of immunomodulatory drug therapy

Benjamin W Teh, Simon J Harrison, Leon J Worth, Tim Spelman, Karin A Thursky, Monica A Slavin

Journal article  |  2015  |  British Journal of Haematology

Plasmacytoma of the testis in a patient with relapsed and refractory multiple myeloma: Case report and review of the literature

Munad Khan, Nieroshan Rajarubendra, Sarah Azer, Alison Skene, Simon J Harrison, Belinda Campbell, Nathan Lawrentschuk

Journal article  |  2015  |  Urology Annals

Ceritinib in patients with advanced anaplastic lymphoma kinase-rearranged anaplastic large-cell lymphoma

Heike Richly, Tae Min Kim, Martin Schuler, Dong-Wan Kim, Simon J Harrison, Alice T Shaw, Anthony L Boral, Alejandro Yovine, Benjamin Solomon

Journal article  |  2015  |  Blood

Comment on "Retrospective matched-pairs analysis of bortezomib plus dexamethasone versus bortezomib monotherapy in relapsed multiple myeloma"

Simon J Harrison, Hang Quach, Andrew Spencer, H Miles Prince

Journal article  |  2015  |  Haematologica

Intracranial involvement by multiple myeloma

A Lasocki, S Gangatharan, F Gaillard, SJ Harrison

Journal article  |  2015  |  Clinical Radiology

Risks and burden of viral respiratory tract infections in patients with multiple myeloma in the era of immunomodulatory drugs and bortezomib: experience at an Australian Cancer Hospital

Benjamin W Teh, Leon J Worth, Simon J Harrison, Karin A Thursky, Monica A Slavin

Journal article  |  2015  |  Supportive Care in Cancer

Errata: Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia (Blood (2011) 117, 13 (3658-3668))

MJ Bishton, SJ Harrison, BP Martin

Journal article  |  2015  |  Blood

The addition of dexamethasone to bortezomib for patients with relapsed multiple myeloma improves outcome but ongoing maintenance therapy has minimal benefit

Simon J Harrison, Hang Quach, Emma Link, Huaibao Feng, Joanne Dean, Michael Copeman, Helgi Van de Velde, Anthony Schwarer, Bartrum Baker, Andrew Spencer, John Catalano, Philip Campbell, Bradley Augustson, Ken Romeril, Henry Miles Prince

Journal article  |  2015  |  American Journal of Hematology

Myelosuppressive Therapies Significantly Increase ProInflammatory Cytokines and Directly Cause Bone Loss

Julie M Quach, Maria Askmyr, Tanja Jovic, Emma K Baker, Nicole C Walsh, Simon J Harrison, Paul Neeson, David Ritchie, Peter R Ebeling, Louise E Purton

Journal article  |  2015  |  Journal of Bone and Mineral Research

Management of systemic AL amyloidosis: recommendations of the Myeloma Foundation of Australia Medical and Scientific Advisory Group

N Weber, P Mollee, B Augustson, R Brown, L Catley, J Gibson, S Harrison, PJ Ho, N Horvath, W Jaksic, D Joshua, H Quach, AW Roberts, A Spencer, J Szer, D Talaulikar, B To, A Zannettino, HM Prince

Journal article  |  2015  |  Internal Medicine Journal

Treatment of patients with multiple myeloma who are not eligible for stem cell transplantation: position statement of the myeloma foundation of Australia Medical and Scientific Advisory Group

H Quach, D Joshua, J Ho, J Szer, A Spencer, S Harrison, P Mollee, AW Roberts, N Horvath, D Talaulikar, B To, A Zannettino, R Brown, L Catley, B Augustson, W Jaksic, J Gibson, HM Prince

Journal article  |  2015  |  Internal Medicine Journal

Prevention of viral infections in patients with multiple myeloma: the role of antiviral prophylaxis and immunization

Benjamin W Teh, Monica A Slavin, Simon J Harrison, Leon J Worth

Journal article  |  2015  |  Expert Review of Anti-infective Therapy

Treatment of patients with multiple myeloma who are eligible for stem cell transplantation: position statement of the Myeloma Foundation of Australia Medical and Scientific Advisory Group

H Quach, D Joshua, J Ho, J Szer, A Spencer, SJ Harrison, P Mollee, AW Roberts, N Horvath, D Talulikar, B To, A Zannettino, R Brown, L Catley, B Augustson, W Jaksic, J Gibson, HM Prince

Journal article  |  2015  |  Internal Medicine Journal

The utility and limitations of F-18-fluorodeoxyglucose positron emission tomography with computed tomography in patients with primary mediastinal B-cell lymphoma: single institution experience and literature review

Chan Y Cheah, Michael S Hofman, John F Seymour, David S Ritchie, Michael Dickinson, Andrew Wirth, H Miles Prince, Max Wolf, Elchanan H Januszcewicz, Dennis A Carney, Kirsten E Herbert, Simon J Harrison, Kate L Burbury, Constantine S Tam

Journal article  |  2015  |  Leukemia & Lymphoma

Invasive fungal infections in patients with multiple myeloma: a multi-center study in the era of novel myeloma therapies

Benjamin W Teh, Jasmine C Teng, Karin Urbancic, Andrew Grigg, Simon J Harrison, Leon J Worth, Monica A Slavin, Karin A Thursky

Journal article  |  2015  |  Haematologica

The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myeloma

Andrew Spencer, Sung-Soo Yoon, Simon J Harrison, Shannon R Morris, Deborah A Smith, Richard A Brigandi, Jennifer Gauvin, Rakesh Kumar, Joanna B Opalinska, Christine Chen

Journal article  |  2014  |  Blood

A multicentre retrospective comparison of central nervous system prophylaxis strategies among patients with high-risk diffuse large B-cell lymphoma

CY Cheah, KE Herbert, K O'Rourke, GA Kennedy, A George, PL Fedele, M Gilbertson, SY Tan, DS Ritchie, SS Opat, HM Prince, M Dickinson, K Burbury, M Wolf, EH Januszewicz, CS Tam, DA Westerman, DA Carney, SJ Harrison, JF Seymour

Journal article  |  2014  |  British Journal of Cancer

Immune regulatory effects of panobinostat in patients with Hodgkin lymphoma through modulation of serum cytokine levels and T-cell PD1 expression

Y Oki, D Buglio, J Zhang, Y Ying, S Zhou, A Sureda, D Ben-Yehuda, PL Zinzani, HM Prince, SJ Harrison, M Kirschbaum, PB Johnston, A Shen, B von Tresckow, A Younes

Journal article  |  2014  |  Blood Cancer Journal

The Choice of Multiple Myeloma Induction Therapy Affects the Frequency and Severity of Oral Mucositis After Melphalan-Based Autologous Stem Cell Transplantation

Shaun Fleming, Simon J Harrison, Piers Blombery, Trish Joyce, Kerrie Stokes, John F Seymour, H Miles Prince, David Ritchie

Journal article  |  2014  |  Clinical Lymphoma Myeloma and Leukemia

Plerixafor plus pegfilgrastim is a safe, effective mobilization regimen for poor or adequate mobilizers of hematopoietic stem and progenitor cells: a phase I clinical trial

KE Herbert, L Demosthenous, G Wiesner, E Link, DA Westerman, N Came, DS Ritchie, S Harrison, JF Seymour, HM Prince

Journal article  |  2014  |  Bone Marrow Transplantation

Limited clinical benefit for surveillance PET-CT scanning in patients with histologically transformed lymphoma in complete metabolic remission following primary therapy

Chan Y Cheah, Michael Dickinson, Michael S Hofman, Anupkumar George, David S Ritchie, H Miles Prince, David Westerman, Simon J Harrison, Kate Burbury, Max Wolf, Henry Januszewicz, Kirsten E Herbert, Dennis A Carney, Constantine Tam, John F Seymour

Journal article  |  2014  |  Annals of Hematology

Early thymus and activation-regulated chemokine (TARC) reduction and response following panobinostat treatment in patients with relapsed/refractory Hodgkin lymphoma following autologous stem cell transplant

Simon J Harrison, Andy K Hsu, Paul Neeson, Anas Younes, Anna Sureda, Andreas Engert, H Miles Prince, Martha Li, Paula Savage, Roberto Bugarini, Denise Williams, Margaret Squier, David S Ritchie

Journal article  |  2014  |  Leukemia & Lymphoma

Myeloma and pregnancy: strange bedfellows?

Amit S Khot, H Miles Prince, Simon J Harrison, John F Seymour

Journal article  |  2014  |  Leukemia & Lymphoma

Changing treatment paradigms for patients with plasma cell myeloma: Impact upon immune determinants of infection

Benjamin W Teh, Simon J Harrison, Marc Pellegrini, Karin A Thursky, Leon J Worth, Monica A Slavin

Journal article  |  2014  |  Blood Reviews

Low Uptake of Upfront Autologous Transplantation for Myeloma in a Jurisdiction With Universal Health Care Coverage: A Population-Based Patterns of Care Study in Australia

Nicole Wong Doo, Michael Coory, Victoria White, Simon J Harrison, H Miles Prince, Jeremy L Millar, Margaret Dimech, Graham G Giles

Journal article  |  2014  |  Clinical Lymphoma, Myeloma & Leukemia

Natural killer T cell defects in multiple myeloma and the impact of lenalidomide therapy

AC Chan, P Neeson, E Leeansyah, K Tainton, H Quach, HM Prince, SJ Harrison, DI Godfrey, D Ritchie, SP Berzins

Journal article  |  2014  |  Clinical and Experimental Immunology

A messenger at the door: cytomegalovirus retinitis in myeloma patients with progressive disease

BW Teh, AS Khot, SJ Harrison, HM Prince, MA Slavin

Journal article  |  2013  |  Transplant Infectious Disease

Limited role for surveillance PET-CT scanning in patients with diffuse large B-cell lymphoma in complete metabolic remission following primary therapy

CY Cheah, MS Hofman, M Dickinson, A Wirth, D Westerman, SJ Harrison, K Burbury, M Wolf, H Januszewicz, K Herbert, HM Prince, DA Carney, DS Ritchie, RJ Hicks, JF Seymour

Journal article  |  2013  |  British Journal of Cancer

Bortezomib with high dose melphalan conditioning for autologous transplant is safe and effective in patients with heavily pretreated and high risk multiple myeloma

Nicole Wong Doo, Philip A Thompson, H Miles Prince, John F Seymour, David Ritchie, Kerrie Stokes, Kate Burbury, Max Wolf, Trish Joyce, Simon J Harrison

Journal article  |  2013  |  Leukemia and Lymphoma

Perceived benefits and barriers to exercise for recently treated patients with multiple myeloma: a qualitative study

Melinda J Craike, Kaye Hose, Kerry S Courneya, Simon J Harrison, Patricia M Livingston

Journal article  |  2013  |  BMC Cancer

Histone deacetylase inhibitors reduce glycoprotein VI expression and platelet responses to collagen related peptide

Mark J Bishton, Elizabeth E Gardiner, Simon J Harrison, H Miles Prince, Ricky W Johnstone

Journal article  |  2013  |  Thrombosis Research

Systematic Review of Quality Improvement Interventions Directed at Cancer Specialists

Michael Coory, Victoria M White, Kristin S Johnson, David J Hill, Michael Jefford, Simon Harrison, Ingrid Winship, Jeremy Millar, Graham G Giles

Journal article  |  2013  |  Journal of Clinical Oncology

Pegfilgrastim compared with filgrastim for cytokine-alone mobilization of autologous haematopoietic stem and progenitor cells

KE Herbert, P Gambell, EK Link, A Mouminoglu, DM Wall, SJ Harrison, DS Ritchie, JF Seymour, HM Prince

Journal article  |  2013  |  Bone Marrow Transplantation

A Risk-Adapted Protocol for Delayed Administration of Filgrastim After High-Dose Chemotherapy and Autologous Stem Cell Transplantation

Amit Khot, Michael Dickinson, Kerrie Stokes, Simon Harrison, Kate Burbury, Shaun Fleming, Dominic Wall, Peter Gambell, H Miles Prince, John F Seymour, David Ritchie

Journal article  |  2013  |  Clinical Lymphoma & Myeloma

Emergence of central nervous system myeloma in the era of novel agents

Shane A Gangatharan, Dennis A Carney, H Miles Prince, Max M Wolf, E Henry Januszewicz, David S Ritchie, Simon J Harrison

Journal article  |  2012  |  Hematological Oncology

A focus on the preclinical development and clinical status of the histone deacetylase inhibitor, romidepsin (depsipeptide, Istodax (R))

Simon J Harrison, Mark Bishton, Susan E Bates, Steven Grant, Richard L Piekarz, Ricky W Johnstone, Yun Dai, Becki Lee, Maria E Araujo, H Miles Prince

Journal article  |  2012  |  Epigenomics

Panobinostat in Patients With Relapsed/Refractory Hodgkin's Lymphoma After Autologous Stem-Cell Transplantation: Results of a Phase II Study

Anas Younes, Anna Sureda, Dina Ben-Yehuda, Pier Luigi Zinzani, Tee-Chuan Ong, H Miles Prince, Simon J Harrison, Mark Kirschbaum, Patrick Johnston, Jennifer Gallagher, Christophe Le Corre, Angela Shen, Andreas Engert

Journal article  |  2012  |  Journal of Clinical Oncology

Complete remission of localised gastric plasmacytomas following definitive radiotherapy

Jennifer Tan, Stephen Lade, Simon Harrison, Stephen Opat, Michael P Mac Manus

Journal article  |  2012  |  Journal of Medical Imaging and Radiation Oncology

Peripheral Blood CD34( ) Cell Enumeration as a Predictor of Apheresis Yield: An Analysis of More Than 1,000 Collections

Peter Gambell, Kirsten Herbert, Michael Dickinson, Kerrie Stokes, Mathias Bressel, Dominic Wall, Simon Harrison, H Miles Prince

Journal article  |  2012  |  Biology of Blood and Marrow Transplantation

M(yeloma)IXing up T maintenance

Simon J Harrison, Amit Khot

Journal article  |  2012  |  Blood

Response of myeloma to the proteasome inhibitor bortezomib is correlated with the unfolded protein response regulator XBP-1

Silvia CW Ling, Edwin KK Lau, Ammira Al-Shabeeb, Angela Nikolic, Albert Catalano, Harry Iland, Noemi Horvath, P Joy Ho, Simon Harrison, Shaun Fleming, Douglas E Joshua, John D Allen

Journal article  |  2012  |  Haematologica

Response Dexamethasone dose alters expression of NK activating receptors in vivo

Andy Hsu, Hang Quach, Tsin Tai, H Miles Prince, Simon J Harrison, Joseph A Trapani, Mark J Smyth, Paul J Neeson, David S Ritchie

Journal article  |  2011  |  Blood

A high rate of durable responses with romidepsin, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma

Simon J Harrison, Hang Quach, Emma Link, John F Seymour, David S Ritchie, Sam Ruell, Joanne Dean, Henry Januszewicz, Ricky Johnstone, Paul Neeson, Michael Dickinson, Jean Nichols, H Miles Prince

Journal article  |  2011  |  Blood

To validate: Is it so simple?

Melisa Darby, Simon J Harrison

Journal article  |  2011  |  Transfusion and Apheresis Science

Bortezomib added to high-dose melphalan as pre-transplant conditioning is safe in patients with heavily pre-treated multiple myeloma

PA Thompson, HM Prince, JF Seymour, D Ritchie, K Stokes, K Burbury, M Wolf, S Peinert, T Joyce, SJ Harrison

Journal article  |  2011  |  Bone Marrow Transplantation

Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia

Mark J Bishton, Simon J Harrison, Benjamin P Martin, Nicole McLaughlin, Chloe James, Emma C Josefsson, Katya J Henley, Benjamin T Kile, H Miles Prince, Ricky W Johnstone

Journal article  |  2011  |  Blood

The immunostimulatory effect of lenalidomide on NK-cell function is profoundly inhibited by concurrent dexamethasone therapy

Andy K Hsu, Hang Quach, Tsin Tai, H Miles Prince, Simon J Harrison, Joseph A Trapani, Mark J Smyth, Paul Neeson, David S Ritchie

Journal article  |  2011  |  Blood

Bortezomib, cyclophosphamide, and dexamethasone: highly effective for rapid reversal of myeloma-associated hyperammonemic encephalopathy

Rebecca Howman, Arti Thakerer, Matthew Pitman, Nik Ding, Philip A Thompson, Amit Khot, Simon J Harrison

Journal article  |  2010  |  Leukemia and Lymphoma

Lessons Learned From an Unusual Presentation of CD3( ), CD56(-) T-Cell Large Granular Lymphocyte Leukemia

Rebecca J Lee, Nicole Ritz, Angela Chi-Ying Chan, Stuart P Berzins, Neil Came, Nigel Curtis, Andrew Lim, Simon James Harrison

Journal article  |  2010  |  Journal of Clinical Oncology

Ex vivo culture of chimeric antigen receptor T cells generates functional CD8( ) T cells with effector and central memory-like phenotype

P Neeson, A Shin, KM Tainton, P Guru, HM Prince, SJ Harrison, S Peinert, MJ Smyth, JA Trapani, MH Kershaw, PK Darcy, DS Ritchie

Journal article  |  2010  |  Gene Therapy

Overview of Histone Deacetylase Inhibitors in Haematological Malignancies.

Mark J Bishton, Ricky W Johnstone, Michael Dickinson, Simon Harrison, H Miles Prince

Journal article  |  2010  |  Pharmaceuticals

Histone deacetylase inhibitors (HDACi) can induce hyperacetylation of both histone and non-histone target resulting in epigenetic ..

Oseltamivir Resistance in Adult Oncology and Hematology Patients Infected with Pandemic (H1N1) 2009 Virus, Australia

Adrian R Tramontana, Biju George, Aeron C Hurt, Joseph S Doyle, Katherine Langan, Alistair B Reid, Janet M Harper, Karin Thursky, Leon J Worth, Dominic E Dwyer, C Orla Morrissey, Paul DR Johnson, Kirsty L Buising, Simon James Harrison, John F Seymour, Patricia E Ferguson, Bin Wang, Justin T Denholm, Allen C Cheng, Monica Slavin

Journal article  |  2010  |  Emerging Infectious Diseases

Gene-modified T cells as immunotherapy for multiple myeloma and acute myeloid leukemia expressing the Lewis Y antigen

S Peinert, HM Prince, PM Guru, MH Kershaw, MJ Smyth, JA Trapani, P Gambell, S Harrison, AM Scott, FE Smyth, PK Darcy, K Tainton, P Neeson, DS Ritchie, D Hoenemann

Journal article  |  2010  |  Gene Therapy

Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma

H Quach, D Ritchie, AK Stewart, P Neeson, S Harrison, MJ Smyth, HM Prince

Journal article  |  2010  |  Leukemia

Clinical Studies of Histone Deacetylase Inhibitors

H Miles Prince, Mark J Bishton, Simon J Harrison

Journal article  |  2009  |  Clinical Cancer Research

Predicting durable remissions following thalidomide therapy for relapsed myeloma

Hang Quach, Linda Mileshkin, John F Seymour, Alvin Milner, David Ritchie, Simon Harrison, David Westerman, H Miles Prince

Journal article  |  2009  |  Leukemia and Lymphoma

Enumeration of blood dendritic cells in patients with multiple myeloma at presentation and through therapy

Simon J Harrison, Ian M Franklin, John DM Campbell

Journal article  |  2008  |  LEUKEMIA & LYMPHOMA

Immunotherapy of multiple myeloma: the start of a long and tortuous journey

Simon J Harrison, Gordon Cook, Robert JB Nibbs, H Miles Prince

Journal article  |  2006  |  EXPERT REVIEW OF ANTICANCER THERAPY