George Jerums

Dietary sodium and potassium intake in people with diabetes: are guidelines being met?

Sara Baqar, Adrian Michalopoulos, George Jerums, Elif I Ekinci

Journal article  |  2020  |  Nutrition & Diabetes

OBJECTIVE: Despite public health bodies advocating for lowering dietary sodium and increasing potassium intake to improve cardiova..

Effect of Salt Supplementation on Sympathetic Activity and Endothelial Function in Salt-Sensitive Type 2 Diabetes

Sara Baqar, Yee Wen Kong, Angela X Chen, Christopher O'Callaghan, Richard J MacIsaac, Maree Bouterakos, Gavin W Lambert, George Jerums, Elisabeth E Lambert, Elif Ekinci

Journal article  |  2020  |  The Journal of Clinical Endocrinology & Metabolism

CONTEXT: Lower sodium intake is paradoxically associated with higher mortality in type 2 diabetes (T2D). OBJECTIVE: To determine w..

Effect of angiotensin II receptor blocker and salt supplementation on short-term blood pressure variability in type 2 diabetes

Angela X Chen, John L Moran, Renata Libianto, Sara Baqar, Christopher O'Callaghan, Richard J MacIsaac, George Jerums, Elif Ekinci

Journal article  |  2020  |  Journal of Human Hypertension

High blood pressure variability (BPV) has been associated with increased cardiovascular (CV) risk. The effect of dietary salt and ..

Diabetes and higher HbA1c levels are independently associated with adverse renal outcomes in inpatients following multiple hospital admissions

N Torkamani, L Churilov, R Robbins, G Jerums, V Beik, N Radcliffe, S Patterson, R Bellomo, J Burns, GK Hart, Q Lam, DA Power, RJ MacIsaac, DF Johnson, J Zajac, E Ekinci

Journal article  |  2020  |  Journal of Diabetes and its Complications

OBJECTIVE: To assess the association between glycaemic status prior to the first hospital presentation with developing adverse ren..

Changes in soluble tumor necrosis factor receptor type 1 levels and early renal function decline in patients with diabetes

Richard J MacIsaac, Matthew Farag, Varuni Obeyesekere, Michele Clarke, Ray Boston, Glenn M Ward, George Jerums, Elif Ekinci

Journal article  |  2019  |  Journal of Diabetes Investigation

The relationship between serial changes in soluble tumor necrosis factor receptor type 1 (TNFR1) levels and an early decline in es..

Comparison of endothelial function and sympathetic nervous system activity along the glucose continuum in individuals with differing metabolic risk profiles and low dietary sodium intake

Sara Baqar, Nora E Straznicky, Gavin Lambert, Yee Wen Kong, John B Dixon, George Jerums, Elif Ilhan Ekinci, Elisabeth Lambert

Journal article  |  2019  |  BMJ Open Diabetes Research & Care

Is hyperfiltration associated with higher urine albumin-to-creatinine ratio at follow up among Indigenous Australians? The eGFR follow-up study

Elif Ekinci, Elizabeth LM Barr, Federica Barzi, Jaquelyne T Hughes, Paul D Lawton, Graham RD Jones, Wendy Hoy, Alan Cass, Mark Thomas, Ashim Sinha, George Jerums, Kerin O'Dea, Richard J MacIsaac, Louise J Maple-Brown

Journal article  |  2019  |  Journal of Diabetes and its Complications

Three Dimensional Glomerular Reconstruction: A Novel Approach to Evaluate Renal Microanatomy in Diabetic Kidney Disease

Niloufar Torkamani, George Jerums, Paul Crammer, Alison Skene, David A Power, Sianna Panagiotopoulos, Michele Clarke, Richard J MacIsaac, Elif I Ekinci

Journal article  |  2019  |  Scientific Reports

The relationship between habitual dietary sodium intake and RAAS blockade on circulating microparticle levels in type two diabetes

Sara Baqar, Dorothy Liu, Lisa F Lincz, Yee Wen Kong, George Jerums, Elif I Ekinci

Journal article  |  2018  |  Clinical Science

Contribution of cardiometabolic risk factors to estimated glomerular filtration rate decline in Indigenous Australians with and without albuminuria - the eGFR Follow-up Study

Elizabeth LM Barr, Federica Barzi, Jaquelyne T Hughes, George Jerums, Kerin O'Dea, Alex DH Brown, Elif I Ekinci, Graham RD Jones, Paul D Lawton, Ashim Sinha, Richard J MacIsaac, Alan Cass, Louise J Maple-Brown

Journal article  |  2018  |  Nephrology

Use of Readily Accessible inflammatory Markers to Predict Diabetic Kidney Disease

Lauren Winter, Lydia A Wong, George Jerums, Jas-Mine Seah, Michele Clarke, Sih Min Tan, Melinda T Coughlan, Richard J MacIsaac, Elif I Ekinci

Journal article  |  2018  |  Frontiers in Endocrinology

High Baseline Levels of Tumor Necrosis Factor Receptor 1 Are Associated With Progression of Kidney Disease in Indigenous Australians With Diabetes: The eGFR Follow-up Study

Elizabeth LM Barr, Federica Barzi, Jaquelyne T Hughes, George Jerums, Wendy E Hoy, Kerin O'Dea, Graham RD Jones, Paul D Lawton, Alex DH Brown, Mark Thomas, Elif I Ekinci, Ashim Sinha, Alan Cass, Richard J MacIsaac, Louise J Maple-Brown

Journal article  |  2018  |  Diabetes Care

Glycemic Control as Primary Prevention for Diabetic Kidney Disease

Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2018  |  Advances in Chronic Kidney Disease

Trajectories of eGFR decline over a four year period in an Indigenous Australian population at high risk of CKD-the eGFR follow up study

Federica Barzi, Graham RD Jones, Jaquelyne T Hughes, Paul D Lawton, Wendy Hoy, Kerin O'Dea, George Jerums, Richard J MacIsaac, Alan Cass, Louise J Maple-Brown

Journal article  |  2018  |  Clinical Biochemistry

Relationship between urinary sodium-to-potassium ratio and ambulatory blood pressure in patients with diabetes mellitus

Renata Libianto, John Moran, Christopher O'Callaghan, Sara Baqar, Angela X Chen, Scott T Baker, Michelle Clarke, Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2018  |  Clinical and Experimental Pharmacology and Physiology

Cross-sectional associations of albuminuria among Aboriginal and Torres Strait Islander adults: the eGFR Study

JT Hughes, LJ Maple-Brown, M Thomas, PD Lawton, A Sinha, A Cass, F Barzi, GRD Jones, G Jerums, RJ MacIsaac, K O'Dea, WE Hoy

Journal article  |  2018  |  Nephrology

Long-term intra-individual variability of albuminuria in type 2 diabetes mellitus: implications for categorization of albumin excretion rate

Amanda Leong, Elif Ilhan Ekinci, Cattram Nguyen, Michele Milne, Mariam Hachem, Matthew Dobson, Richard J MacIsaac, George Jerums

Journal article  |  2017  |  BMC Nephrology

Relationship of Uric Acid Clearance and Serum Uric Acid Levels with All-Cause Mortality in Type 2 Diabetes

Geetha Theverkalam, Ray Boston, Glenn M Ward, George Jerums, Elif I Ekinci, Richard J Macisaac

Conference Proceedings  |  2017  |  DIABETES

Effects of glycaemic management on diabetic kidney disease

Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2017  |  World Journal of Diabetes

Comparison of creatinine and cystatin C based eGFR in the estimation of glomerular filtration rate in Indigenous Australians: The eGFR Study

Elizabeth LM Barr, Louise J Maple-Brown, Federica Barzi, Jaquelyne T Hughes, George Jerums, Elif I Ekinci, Andrew G Ellis, Graham RD Jones, Paul D Lawton, Cherian Sajiv, Sandawana W Majoni, Alex DH Brown, Wendy E Hoy, Kerin O'Dea, Alan Cass, Richard J MacIsaac

Journal article  |  2017  |  Clinical Biochemistry

Clinical predictive factors in diabetic kidney disease progression

Nicholas J Radcliffe, Jas-Mine Seah, Michele Clarke, Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2017  |  Journal of Diabetes Investigation

Sodium and Its Role in Cardiovascular Disease - The Debate Continues

Yee Wen Kong, Sara Baqar, George Jerums, Elif I Ekinci

Journal article  |  2016  |  Frontiers in Endocrinology

Progression of Kidney Disease in Indigenous Australians: The eGFR Follow-up Study

Louise J Maple-Brown, Jaquelyne T Hughes, Rebecca Ritte, Federica Barzi, Wendy E Hoy, Paul D Lawton, Graham RD Jones, Elizabeth Death, Alison Simmonds, Ashim K Sinha, Sajiv Cherian, Mark AB Thomas, Robyn McDermott, Alex DH Brown, Kerin O'Dea, George Jerums, Alan Cass, Richard J Maclsaac

Journal article  |  2016  |  Clinical Journal of the American Society of Nephrology

Assessing the Value of BMI and Aerobic Capacity as Surrogate Markers for the Severity of Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes Who Are Obese

Cassandra Smith, Muhammad Asrar ul Haq, George Jerums, Erik Hanson, Alan Hayes, Jason D Allen, Melissa Sbaraglia, Steve Selig, Chiew Wong, David L Hare, Itamar Levinger

Journal article  |  2016  |  Clinical Medicine Insights: Cardiology

Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis

Melinda T Coughlan, Gavin C Higgins, Nguyen Tuong-Vi, Sally A Penfold, Vicki Thallas-Bonke, Sih Mm Tan, Georg Ramm, Nicole J Van Bergen, Darren C Henstridge, Karly C Sourris, Brooke E Harcourt, Ian A Trounce, Portia M Robb, Adrienne Laskowski, Sean L McGee, Amanda J Genders, Ken Walder, Brian G Drew, Paul Gregorevic, Hongwei Qian, et al.

Journal article  |  2016  |  Diabetes

A Single Dose of Prednisolone as a Modulator of Undercarboxylated Osteocalcin and Insulin Sensitivity Post-Exercise in Healthy Young Men: A Study Protocol

Itamar Levinger, Tara C Brennan-Speranza, Nigel K Stepto, George Jerums, Lewan Parker, Glenn K McConell, Mitchell Anderson, Andrew Garnham, David L Hare, Peter R Ebeling, Ego Seeman

Journal article  |  2016  |  JMIR Research Protocols

Elevated baseline glomerular filtration rate (GFR) is independently associated with a more rapid decline in renal function of patients with type 1 diabetes

Hilary J Thomson, Elif I Ekinci, Nicholas J Radcliffe, Jas-mine Seah, Richard J MacIsaac, George Jerums, Erosha Premaratne

Journal article  |  2016  |  Journal of Diabetes and its Complications

Glucose-loading reduces bone remodeling in women and osteoblast function in vitro

Itamar Levinger, Ego Seeman, George Jerums, Glenn K McConell, Mark S Rybchyn, Samantha Cassar, Elizabeth Byrnes, Steve Selig, Rebecca S Mason, Peter R Ebeling, Tara C Brennan-Speranza

Journal article  |  2016  |  Physiological Reports

The effects of muscle contraction and recombinant osteocalcin on insulin sensitivity ex vivo

I Levinger, X Lin, X Zhang, TC Brennan-Speranza, B Volpato, A Hayes, G Jerums, E Seeman, G McConell

Journal article  |  2016  |  Osteoporosis International

Muscle atrophy in patients with Type 2 Diabetes Mellitus: roles of inflammatory pathways, physical activity and exercise

Ben D Perry, Marissa K Caldow, Tara C Brennan-Speranza, Melissa Sbaraglia, George Jerums, Andrew Garnham, Chiew Wong, Pazit Levinger, Muhammad Asrar ul Haq, David L Hare, S Russ Price, Itamar Levinger

Journal article  |  2016  |  Exercise Immunology Review

Association of sex hormone-binding globulin and free testosterone with mortality in men with type 2 diabetes mellitus

Aye N Tint, Rudolf Hoermann, Henry Wong, Elif I Ekinci, Richard J MacIsaac, George Jerums, Jeffrey D Zajac, Mathis Grossmann

Journal article  |  2016  |  European Journal of Endocrinology

Estimating glomerular filtration rate: Performance of the CKD-EPI equation over time in patients with type 2 diabetes

Anna J Wood, Leonid Churilov, Nayomi Perera, David Thomas, Aurora Poon, Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2016  |  Journal of Diabetes and its Complications

Can Targeting the Incretin Pathway Dampen RAGE-Mediated Events in Diabetic Nephropathy?

Karly C Sourris, Henry Yao, George Jerums, Mark E Cooper, Elif I Ekinci, Melinda T Coughlan

Journal article  |  2016  |  Current Drug Targets

Cardio-renal protection with empagliflozin

RJ MacIsaac, G Jerums, EI Ekinci

Journal article  |  2016  |  Annals of Translational Medicine

Cardiovascular (CV) and kidney disease are common and significant complications in people with type 2 diabetes (T2DM). CV disease ..

The Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation does not improve the underestimation of Glomerular Filtration Rate (GFR) in people with diabetes and preserved renal function

Richard J MacIsaac, Elif I Ekinci, Erosha Premaratne, Zhong X Lu, Jas-mine Seah, Yue Li, Ray Boston, Glenn M Ward, George Jerums

Journal article  |  2015  |  BMC Nephrology

Hyperfiltration in Indigenous Australians with and without diabetes

Elif I Ekinci, Jaquelyne T Hughes, Mark D Chatfield, Paul D Lawton, Graham RD Jones, Andrew G Ellis, Alan Cass, Mark Thomas, Richard J MacIsaac, Kerin O'Dea, George Jerums, Louise J Maple-Brown

Journal article  |  2015  |  Nephrology Dialysis Transplantation

Short-term dietary salt supplementation blunts telmisartan induced increases in plasma renin activity in hypertensive patients with type 2 diabetes mellitus

Angela X Chen, George Jerums, Sara Baqar, Elisabeth Lambert, Goji Somarajah, Georgina Thomas, Christopher O'Callaghan, Richard J MacIsaac, Elif I Ekinci

Journal article  |  2015  |  Clinical Science

Cardiovascular outcomes with antihypertensive therapy in type 2 diabetes: an analysis of intervention trials

G Jerums, S Panagiotopoulos, E Ekinci, RJ MacIsaac

Journal article  |  2015  |  Journal of Human Hypertension

Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides

Joost P Schanstra, Petra Zuerbig, Alaa Alkhalaf, Angel Argiles, Stephan JL Bakker, Joachim Beige, Henk JG Bilo, Christos Chatzikyrkou, Mohammed Dakna, Jesse Dawson, Christian Delles, Hermann Haller, Marion Haubitz, Holger Husi, Joachim Jankowski, George Jerums, Nanne Kleefstra, Tatiana Kuznetsova, David M Maahs, Jan Menne, et al.

Journal article  |  2015  |  Journal of the American Society of Nephrology

How does exercise affect kidney disease in T1DM?

George Jerums, Richard J MacIsaac

Journal article  |  2015  |  Nature Reviews Endocrinology

Deficiency in Apoptosis Inducing Factor Recapitulates Diabetic Nephropathy via Aberrant Mitochondrial Homeostasis

Melinda T Coughlan, Gavin C Higgins, Tuong-Vi Nguyen, Sally A Penfold, Vicki Thallas-Bonke, Sih Min Tan, Georg Ramm, Nicole J Van Bergen, Darren C Henstridge, Ian A Trounce, Karly C Sourris, Brooke E Harcourt, Portia M Robb, Adrienne Laskowski, Sean L Mcgee, Ken Walder, Paul Gregorevic, Hongwei Qian, Merlin C Thomas, Brian G Drew, et al.

Conference Proceedings  |  2015  |  DIABETES

Adding Measures of Body Composition to the CKD-EPI GFR Estimating Equation in Indigenous Australians: The eGFR Study

Louise J Maple-Brown, Jaquelyne T Hughes, Mark D Chatfield, Leigh C Ward, Leonard S Piers, Graham RD Jones, Paul D Lawton, Andrew G Ellis, Alan Cass, Wendy E Hoy, Kerin O'Dea, Richard J MacIsaac, George Jerums

Journal article  |  2015  |  American Journal of Kidney Diseases

The impact of hyperfiltration on the diabetic kidney

E Premaratne, S Verma, EI Ekinci, G Theverkalam, G Jerums, RJ MacIsaac

Journal article  |  2015  |  Diabetes & Metabolism

The shifting paradigm of albuminuria in diabetic kidney disease

AK Watts, KM Dwyer, EI Ekinci, G Jerums, RJ MacIsaac

Journal article  |  2015  |  Medicine Today

The Effect of Acute Exercise on Undercarboxylated Osteocalcin and Insulin Sensitivity in Obese Men

Itamar Levinger, George Jerums, Nigel K Stepto, Lewan Parker, Fabio R Serpiello, Glenn K McConell, Mitchell Anderson, David L Hare, Elizabeth Byrnes, Peter R Ebeling, Ego Seeman

Journal article  |  2014  |  Journal of Bone and Mineral Research

Spectrum of renal disease in diabetes

Jessie Teng, Karen M Dwyer, Prue Hill, Emily See, Elif I Ekinci, George Jerums, Richard J Macisaac

Journal article  |  2014  |  Nephrology

Serum vitamin D levels, diabetes and cardio-metabolic risk factors in Aboriginal and Torres Strait Islander Australians

Louise J Maple-Brown, Jaquelyne T Hughes, Zhong X Lu, Kanakamani Jeyaraman, Paul Lawton, Graham RD Jones, Andrew Ellis, Ashim Sinha, Alan Cass, Richard J MacIsaac, George Jerums, Kerin O'Dea

Journal article  |  2014  |  Diabetology & Metabolic Syndrome

Performance of formulas for estimating glomerular filtration rate in Indigenous Australians with and without Type 2 diabetes: the eGFR Study

LJ Maple-Brown, EI Ekinci, JT Hughes, M Chatfield, PD Lawton, GRD Jones, AG Ellis, A Sinha, A Cass, WE Hoy, K O'Dea, G Jerums, RJ MacIsaac

Journal article  |  2014  |  Diabetic Medicine

'Progressive diabetic nephropathy. How useful is microalbuminuria?: Contra'

Richard J Maclsaac, Elif I Ekinci, G Jerums

Journal article  |  2014  |  Kidney International

Predicting renal function decline in patients with T2DM

George Jerums, Richard J MacIsaac

Journal article  |  2014  |  Nature Reviews Endocrinology

Relationship Between Urinary Sodium Excretion Over Time and Mortality in Type 2 Diabetes

Elif I Ekinci, John L Moran, Merlin C Thomas, Karey Cheong, Sophie Clarke, Angela Chen, Matt Dobson, Amanda Leong, Richard J MacIsaac, George Jerums

Journal article  |  2014  |  Diabetes Care

Markers of and Risk Factors for the Development and Progression of Diabetic Kidney Disease

Richard J MacIsaac, Elif I Ekinci, George Jerums

Journal article  |  2014  |  American Journal of Kidney Diseases

Relationship between urinary sodium excretion and serum aldosterone in patients with diabetes in the presence and absence of modifiers of the renin-.a ngiotensin-aldosterone system

Renata Libianto, George Jerums, Que Lam, Angela Chen, Sara Baqar, Felicity Pyrlis, Richard J Macisaac, John Moran, Elif I Ekinci

Journal article  |  2014  |  Clinical Science

Reducing the complications of type 2 diabetes: Challenges in individualising care

JM Seah, H Yao, RJ MacIsaac, EI Ekinci, G Jerums

Journal article  |  2014  |  Medicine Today

Prevalence, predictors and evolution of echocardiographically defined cardiac abnormalities in adults with type 1 diabetes: an observational cohort study

Bryan Wai, Sheila K Patel, Michelle Ord, Richard J MacIsaac, George Jerums, Piyush M Srivastava, Louise M Burrell

Journal article  |  2014  |  Journal of Diabetes and its Complications

Atypical presentations of diabetic nephropathy and novel therapies

LJ Imbriano, JK Maesaka, J Mattana, S Shirazian, G Jerums

Book Chapter  |  2014

Effect of exercise training on left ventricular remodeling in diabetic patients with diastolic dysfunction: rationale and design.

Muhammad Asrar Ul Haq, Chiew Wong, Itamar Levinger, Piyush M Srivastava, Melissa Sbaraglia, Deidre Toia, George Jerums, Steve Selig, David L Hare

Journal article  |  2014  |  Clinical Medicine: Cardiology

INTRODUCTION: This study will examine the effects of combined aerobic and resistance training on left ventricular remodeling in di..

Renal Structure in Normoalbuminuric and Albuminuric Patients With Type 2 Diabetes and Impaired Renal Function

Elif I Ekinci, George Jerums, Alison Skene, Paul Crammer, David Power, Karey Y Cheong, Sianna Panagiotopoulos, Karen McNeil, Scott T Baker, Paola Fioretto, Richard J MacIsaac

Journal article  |  2013  |  Diabetes Care

New insights into the effects of primary hyperparathyroidism on the cortical and trabecular compartments of bone

Thuy DT Vu, Xiao Fang Wang, Qingju Wang, Natalie E Cusano, Dinaz Irani, Barbara C Silva, Ali Ghasem-Zadeh, Julia Udesky, Megan E Romano, Roger Zebaze, George Jerums, Stephanie Boutroy, John P Bilezikian, Ego Seeman

Journal article  |  2013  |  Bone

Development of a novel polyclonal antibody-based immunoassay for the quantitation of non-albumin urinary proteins

WB Haigh, DM Guralski, LM Arrigo, JT Letsinger, M Clarke, RJ MacIsaac, G Jerums, DL Very

Journal article  |  2013  |  The Open Clinical Chemistry Journal

Background: Better diagnostic methods to detect urinary proteinuria or albuminuria, important indicators of di..

Early glomerular filtration rate loss as a marker of diabetic nephropathy

G Jerums, E Ekinci, S Panagiotopoulos, RJ MacIsaac

Journal article  |  2012  |  European Endocrinology

In the early 1980s, studies in type 1 diabetes suggested that glomerular filtration rate (GFR) loss begins with the onset of macro..

Depressed mood, glycaemic control and functional capacity in overweight/obese men with and without type 2 diabetes

Itamar Levinger, Steve Selig, George Jerums, Andrew Stewart, Cadeyrn J Gaskin, David L Hare

Journal article  |  2012  |  Diabetology & Metabolic Syndrome

Accurate Assessment of Kidney Function in Indigenous Australians: The Estimated GFR Study

Louise J Maple-Brown, Jaquelyne T Hughes, Paul D Lawton, Graham RD Jones, Andrew G Ellis, Katrina Drabsch, Alex DH Brown, Alan Cass, Wendy E Hoy, Richard J MacIsaac, Kerin O'Dea, George Jerums

Journal article  |  2012  |  American Journal of Kidney Diseases

Chronic kidney disease and measurement of albuminuria or proteinuria: a position statement

David W Johnson, Graham RD Jones, Timothy H Mathew, Marie J Ludlow, Stephen J Chadban, Tim Usherwood, Kevan Polkinghorne, Stephen Colagiuri, George Jerums, Richard MacIsaac, Helen Martin

Journal article  |  2012  |  MEDICAL JOURNAL OF AUSTRALIA

ACCURATE ASSESSMENT OF KIDNEY FUNCTION IN INDIGENOUS AUSTRALIANS: THE EGFR STUDY

LJ Maple-Brown, JT Hughes, PD Lawton, GRD Jones, AG Ellis, K Drabsch, A Cass, WE Hoy, RJ Macisaac, K O'Dea, G Jerums

Conference Proceedings  |  2012  |  NEPHROLOGY

Increased bone mineral density in Aboriginal and Torres Strait Islander Australians: Impact of body composition differences

LJ Maple-Brown, J Hughes, LS Piers, LC Ward, J Meerkin, JA Eisman, JR Center, NA Pocock, G Jerums, K O'Dea

Journal article  |  2012  |  Bone

Early glomerular filtration rate loss as a marker of diabetic nephropathy

G Jerums, E Ekinci, S Panagiotopoulos, RJ MacIsaac

Journal article  |  2012  |  US endocrinology

In the early 1980s, studies in type 1 diabetes suggested that glomerular filtration rate (GFR) loss begins with the onset of macro..

Less fat reduction per unit weight loss in type 2 diabetic compared with nondiabetic obese individuals completing a very-low-calorie diet program

Scott T Baker, George Jerums, Luke A Prendergast, Sianna Panagiotopoulos, Boyd J Strauss, Joseph Proietto

Journal article  |  2012  |  Metabolism: Clinical and Experimental

Estimating dual-energy X-ray absorptiometry-derived total body skeletal muscle mass using single-slice abdominal magnetic resonance imaging in obese subjects with and without diabetes: a pilot study

ST Baker, BJ Strauss, LA Prendergast, S Panagiotopoulos, GE Thomas, T Vu, J Proietto, G Jerums

Journal article  |  2012  |  European Journal of Clinical Nutrition

The CTGF gene-945 G/C polymorphism is not associated with cardiac or kidney complications in subjects with type 2 diabetes

Sheila K Patel, Bryan Wai, Richard J MacIsaac, Sharon Grant, Elena Velkoska, Michelle Ord, Sianna Panagiotopoulos, George Jerums, Piyush M Srivastava, Louise M Burrell

Journal article  |  2012  |  Cardiovascular Diabetology

Diabetic Chronic Kidney Disease

RJ Macisaac, G Jerums, GF Watts

Book Chapter  |  2012

Hypocalcemia induced by raloxifene.

Thuy DT Vu, Suresh Varadarajan, Ego Seeman, George Jerums, Richard J MacIsaac

Journal article  |  2012  |  Current Drug Safety

Raloxifene is an anti-resorptive agent used in postmenopausal osteoporosis. This is the first report of the occurrence of clinical..

Association of ACE2 Genetic Variants With Blood Pressure, Left Ventricular Mass, and Cardiac Function in Caucasians With Type 2 Diabetes

Sheila K Patel, Bryan Wai, Michelle Ord, Richard J MacIsaac, Sharon Grant, Elena Velkoska, Sianna Panagiotopoulos, George Jerums, Piyush M Srivastava, Louise M Burrell

Journal article  |  2012  |  American Journal of Hypertension

Early Glomerular Filtration Rate Loss as a Marker of Diabetic Nephropathy

G Jerums, EI Ekinci, S Panagiotopoulos, RJ Macisaac

Journal article  |  2012  |  European Nephrology

Estimating glomerular filtration rate in diabetes using serum cystatin C

RJ MacIsaac, E Premaratne, G Jerums

Journal article  |  2011  |  Clinical Biochemist Reviews

Intensive Glucose Control and Cardiovascular Outcomes in Type 2 Diabetes

Richard J MacIsaac, George Jerums

Journal article  |  2011  |  Heart, Lung and Circulation

New approaches for the evaluation of renal vascular function in diabetes

G Jerums, RJ MacIsaac

Journal article  |  2011  |  Diabetologia

Failure of functional imaging with gallium-68-DOTA-D-Phe1-Tyr3-octreotide positron emission tomography to localize the site of ectopic adrenocorticotropic hormone secretion: a case report.

Linsey U Gani, Emily J Gianatti, Ada S Cheung, George Jerums, Richard J Macisaac

Journal article  |  2011  |  Journal of Medical Case Reports

INTRODUCTION: The diagnostic efficacy of biochemical and imaging modalities for investigating the causes of Cushing's syndrome are..

RESISTANCE TRAINING IMPROVES DEPRESSIVE SYMPTOMS IN INDIVIDUALS AT HIGH RISK FOR TYPE 2 DIABETES

Itamar Levinger, Steve Selig, Craig Goodman, George Jerums, Andrew Stewart, David L Hare

Journal article  |  2011  |  Journal of Strength and Conditioning Research

Effects of perindopril-indapamide on left ventricular diastolic function and mass in patients with type 2 diabetes: the ADVANCE Echocardiography Substudy

Robert N Doughty, GA Whalley, GD Gamble, J Baker, J Chalmers, M Cooper, K Cruickshank, P Dixon, P Dunne, D Eccleston, G Jerums, R Luke, B McGrath, C Nolan, A Patel, N Poulter, P Phillips, R Scott, J Singh, R Smith, et al.

Journal article  |  2011  |  Journal of Hypertension

Response to Comment on: Ekinci et al. Dietary Salt Intake and Mortality in Patients With Type 2 Diabetes. Diabetes Care 2011;34:703–709.

Elif I Ekinci, Richard J MacIsaac, Merlin C Thomas, George Jerums

Journal article  |  2011  |  Diabetes Care

The effect of acute exercise on undercarboxylated osteocalcin in obese men

I Levinger, R Zebaze, G Jerums, DL Hare, S Selig, E Seeman

Journal article  |  2011  |  Osteoporosis International

Oxygen (O-2) kinetics during early recovery from peak exercise in patients with Type 2 diabetes

I Levinger, M Varley, G Jerums, DL Hare, S Selig

Journal article  |  2011  |  Diabetic Medicine

Dietary Salt Intake and Mortality in Patients With Type 2 Diabetes

Elif I Ekinci, Sophie Clarke, Merlin C Thomas, John L Moran, Karey Cheong, Richard J MacIsaac, George Jerums

Journal article  |  2011  |  Diabetes Care

Advanced Glycation Urinary Protein-Bound Biomarkers and Severity of Diabetic Nephropathy in Man

Melinda T Coughlan, Sheila K Patel, George Jerums, Sally A Penfold, Nguyen Tuong-Vi, Karly C Sourris, Sianna Panagiotopoulos, Piyush M Srivastava, Mark E Cooper, Louise M Burrell, Richard J MacIsaac, Josephine M Forbes

Journal article  |  2011  |  American Journal of Nephrology

High sodium and low potassium intake in patients with Type 2 diabetes

EI Ekinci, KY Cheong, M Dobson, E Premaratne, S Finch, RJ MacIsaac, G Jerums

Journal article  |  2010  |  Diabetic Medicine

Chronic type 1 diabetes in spontaneously hypertensive rats leads to exacerbated cardiac fibrosis

Mary Jane Black, Angelo D'Amore, Alana Auden, Laura Stamp, Tanya Osicka, Sianna Panagiotopoulos, George Jerums

Journal article  |  2010  |  Cardiovascular Pathology

Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease

David M Good, Petra Zuerbig, Angel Argiles, Hartwig W Bauer, Georg Behrens, Joshua J Coon, Mohammed Dakna, Stephane Decramer, Christian Delles, Anna F Dominiczak, Jochen HH Ehrich, Frank Eitner, Danilo Fliser, Moritz Frommberger, Arnold Ganser, Mark A Girolami, Igor Golovko, Wilfried Gwinner, Marion Haubitz, Stefan Herget-Rosenthal, et al.

Journal article  |  2010  |  Molecular & Cellular Proteomics

The clinical significance of hyperfiltration in diabetes

G Jerums, E Premaratne, S Panagiotopoulos, RJ MacIsaac

Journal article  |  2010  |  Diabetologia

Urinary Collagen Fragments Are Significantly Altered in Diabetes: A Link to Pathophysiology

David M Maahs, Justyna Siwy, Angel Argiles, Marie Cerna, Christian Delles, Anna F Dominiczak, Nathalie Gayrard, Alexander Iphoefer, Lothar Jaensch, George Jerums, Karel Medek, Harald Mischak, Gerjan J Navis, Johannes M Roob, Kasper Rossing, Peter Rossing, Ivan Rychlik, Eric Schiffer, Roland E Schmieder, Thomas C Wascher, et al.

Journal article  |  2010  |  PLoS One

Type 2 diabetes Controlling hyperglycaemia with early insulin use

Richard MacIsaac, Ada Cheung, George Jerums

Journal article  |  2010  |  Australian Family Physician

Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy

Sally A Penfold, Melinda T Coughlan, Sheila K Patel, Piyush M Srivastava, Karly C Sourris, David Steer, Diane E Webster, Merlin C Thomas, Richard J MacIsaac, George Jerums, Louise M Burrell, Mark E Cooper, Josephine M Forbes

Journal article  |  2010  |  Kidney International

Salt supplementation blunts the blood pressure response to telmisartan with or without hydrochlorothiazide in hypertensive patients with type 2 diabetes

EI Ekinci, G Thomas, RJ MacIsaac, C Johnson, C Houlihan, S Panagiotopoulos, E Premaratne, H Hao, S Finch, C O'Callaghan, G Jerums

Journal article  |  2010  |  Diabetologia

Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy (Diabetes (2002) 51, (3274-3282))

JM Forbes, ME Cooper, V Thallas, WC Burns, MC Thomas, GC Brammar, F Lee, SL Grant, LA Burrell, G Jerums, TM Osicka

Journal article  |  2010  |  Diabetes

Prevention and management of chronic kidney disease in type 2 diabetes

S Chadban, M Howell, S Twigg, M Thomas, G Jerums, A Cass, D Campbell, K Nicholls, A Tong, G Mangos, A Stack, RJ MacIsaac, S Girgis, R Colagiuri, S Colagiuri, J Craig

Journal article  |  2010  |  Nephrology

Cost-effectiveness and socioeconomic implications of prevention and management of chronic kidney disease in type 2 diabetes

S Chadban, M Howell, S Twigg, M Thomas, G Jerums, A Cass, D Campbell, K Nicholls, A Tong, G Mangos, A Stack, RJ MacIsaac, S Girgis, R Colagiuri, S Colagiuri, J Craig

Journal article  |  2010  |  Nephrology

Assessment of kidney function in type 2 diabetes

S Chadban, M Howell, S Twigg, M Thomas, G Jerums, A Cass, D Campbell, K Nicholls, A Tong, G Mangos, A Stack, RJ MacIsaac, S Girgis, R Colagiuri, S Colagiuri, J Craig

Journal article  |  2010  |  Nephrology

Carbimazole-induced agranulocytosis: does antineutrophil cytoplasmic antibody have a role?

G Yip, E Ekinci, ST Lee, G Jerums, M Grossmann

Journal article  |  2010  |  Internal Medicine Journal

Study Protocol - Accurate assessment of kidney function in Indigenous Australians: aims and methods of the eGFR Study

Louise J Maple-Brown, Paul D Lawton, Jaquelyne T Hughes, Suresh K Sharma, Graham RD Jones, Andrew G Ellis, Wendy Hoy, Alan Cass, Richard J MacIsaac, Ashim K Sinha, Mark AB Thomas, Leonard S Piers, Leigh C Ward, Katrina Drabsch, Sianna Panagiotopoulos, Robyn McDermott, Kevin Warr, Sajiv Cherian, Alex Brown, George Jerums, et al.

Journal article  |  2010  |  BMC Public Health

Modulation of the Cellular Expression of Circulating Advanced Glycation End-Product Receptors in Type 2 Diabetic Nephropathy

Karly C Sourris, Brooke E Harcourt, Sally A Penfold, Felicia YT Yap, Amy L Morley, Philip E Morgan, Michael J Davies, Scott T Baker, George Jerums, Josephine M Forbes

Journal article  |  2010  |  Experimental Diabetes Research

Akt, AS160, metabolic risk factors and aerobic fitness in middle-aged women

Itamar Levinger, Kirsten F Howlett, Jonathan Peake, Andrew Garnham, David L Hare, George Jerums, Steve Selig, Craig Goodman

Journal article  |  2010  |  Exercise Immunology Review

Type 2 diabetes Controlling hyperglycaemia in type 2 diabetes by the early use of insulin

RJM Macisaac, A Cheung, GJ Jerums

Journal article  |  2010  |  Australian Family Physician

Erratum: Patterns of glycaemic control in Australian primary care (NEFRON 8). (Internal Medicine Journal (2009) 39 (512-518))

RJ MacIsaac, G Jerums, AJ Weekes, MC Thomas

Journal article  |  2009  |  Internal Medicine Journal

Effects and clinical potential of very-low-calorie diets (VLCDs) in type 2 diabetes

Scott Baker, George Jerums, Joseph Proietto

Journal article  |  2009  |  Diabetes Research and Clinical Practice

Nonalbuminuric Renal Impairment in Type 2 Diabetic Patients and in the General Population (National Evaluation of the Frequency of Renal Impairment cO-existing with NIDDM [NEFRON] 11)

Merlin C Thomas, Richard J MacIsaac, George Jerums, Andrew Weekes, John Moran, Jonathan E Shaw, Robert C Atkins

Journal article  |  2009  |  Diabetes Care

PSYCHOLOGICAL RESPONSES TO ACUTE RESISTANCE EXERCISE IN MEN AND WOMEN WHO ARE OBESE

Itamar Levinger, Craig Goodman, David L Hare, George Jerums, Tony Morris, Steve Selig

Journal article  |  2009  |  Journal of Strength and Conditioning Research

Effects of Salt Supplementation on the Albuminuric Response to Telmisartan With or Without Hydrochlorothiazide Therapy in Hypertensive Patients With Type 2 Diabetes Are Modulated by Habitual Dietary Salt Intake

Elif I Ekinci, Georgina Thomas, David Thomas, Cameron Johnson, Richard J MacIsaac, Christine A Houlihan, Sue Finch, Sianna Panagiotopoulos, Chris O'Callaghan, George Jerums

Journal article  |  2009  |  Diabetes Care

Patterns of glycaemic control in Australian primary care (NEFRON 8)

RJ MacIsaac, G Jerums, AJ Weekes, MC Thomas

Journal article  |  2009  |  Internal Medicine Journal

Blood pressure lowering and outcomes in type 2 diabetes: Implications of the blood pressure-lowering arm of the advance trial

RJ MacIsaac, D Barit, G Jerums

Journal article  |  2009  |  Current Hypertension Reviews

Integrating albuminuria and GFR in the assessment of diabetic nephropathy

George Jerums, Sianna Panagiotopoulos, Erosha Premaratne, Richard J MacIsaac

Journal article  |  2009  |  Nature Reviews Nephrology

Functional capacity and quality of life in middle-age men and women with high and low number of metabolic risk factors

Itamar Levinger, Craig Goodman, David L Hare, George Jerums, Steve Selig

Journal article  |  2009  |  International Journal of Cardiology

Low testosterone and anaemia in men with type 2 diabetes

Mathis Grossmann, Sianna Panagiotopolous, Ken Sharpe, Richard J MacIsaac, Sophie Clarke, Jeffrey D Zajac, George Jerums, Merlin C Thomas

Journal article  |  2009  |  Clinical Endocrinology

Inflammation, hepatic enzymes and resistance training in individuals with metabolic risk factors

I Levinger, C Goodman, J Peake, A Garnham, DL Hare, G Jerums, S Selig

Journal article  |  2009  |  Diabetic Medicine

The reliability of the 1RM strength test for untrained middle-aged individuals

Itamar Levinger, Craig Goodman, David L Hare, George Jerums, Deidre Toia, Steve Selig

Journal article  |  2009  |  Journal of Science and Medicine in Sport

Cost-effectiveness of multipronged agressive management vs standard care in type 2 diabetes

R MACISAAC, G JERUMS

Journal article  |  2009  |  Diabetes Management Journal

New and old markers of progression of diabetic nephropathy

G Jerums, E Premaratne, S Panagiotopoulos, S Clarke, DA Power, RJ MacIsaac

Journal article  |  2008  |  Diabetes Research and Clinical Practice

Association between intrarenal arterial resistance and diastolic dysfunction in type 2 diabetes

Richard J MacIsaac, Merlin C Thomas, Sianna Panagiotopoulos, Trudy J Smith, Huming Hao, D Geoffrey Matthews, George Jerums, Louise M Burrell, Piyush M Srivastava

Journal article  |  2008  |  Cardiovascular Diabetology

Low testosterone levels are common and associated with insulin resistance in men with diabetes

Mathis Grossmann, Merlin C Thomas, Sianna Panagiotopoulos, Ken Sharpe, Richard J MacIsaac, Sophie Clarke, Jeffrey D Zajac, George Jerums

Journal article  |  2008  |  Journal of Clinical Endocrinology and Metabolism

Serial measurements of cystatin C are more accurate than creatinine-based methods in detecting declining renal function in type 1 diabetes

Erosha Premaratne, Richard J Macisaac, Sue Finch, Sianna Panagiotopoulos, Elif Ekinci, George Jerums

Journal article  |  2008  |  Diabetes Care

Low Testosterone Levels Are Common and Associated with Insulin Resistance in Men with Diabetes

Mathis Grossmann, Merlin C Thomas, Sianna Panagiotopoulos, Ken Sharpe, Richard J MacIsaac, Sophie Clarke, Jeffrey D Zajac, George Jerums

Journal article  |  2008  |  Journal of Clinical Endocrinology & Metabolism

Outcomes for general medical inpatients with diabetes mellitus and new hyperglycaemia

Scott T Baker, Cherie Y Chiang, Jeffrey D Zajac, Leon A Bach, George Jerums, Richard J Maclsaac

Journal article  |  2008  |  Medical Journal of Australia

BDNF, metabolic risk factors, and resistance training in middle-aged individuals

Itamar Levinger, Craig Goodman, Vance Matthews, David L Hare, George Jerums, Andrew Garnham, Steve Selig

Journal article  |  2008  |  Medicine and Science in Sports and Exercise

Prevalence and predictors of cardiac hypertrophy and dysfunction in patients with Type 2 diabetes

Piyush M Srivastava, Paul Calafiore, Richard J Macisaac, Sheila K Patel, Merlin C Thomas, George Jerums, Louise M Burrell

Journal article  |  2008  |  Clinical Science

Lowering of Proteinuria in Response to Antihypertensive Therapy Predicts Improved Renal Function in Late but Not in Early Diabetic Nephropathy: A Pooled Analysis

George Jerums, Sianna Panagiotopoulos, Erosha Premaratne, David A Power, Richard J MacIsaac

Journal article  |  2008  |  American Journal of Nephrology

Lowering of proteinuria in response to antihypertensive therapy predicts improved renal function in late but not in early diabetic nephropathy: A pooled analysis

George Jerums, Sianna Panagiotopoulos, Erosha Premaratne, David A Power, Richard J Maclsaac

Journal article  |  2008  |  American Journal of Nephrology

NPHS2 variation in focal and segmental glomerulosclerosis

Stephen J Tonna, Alexander Needham, Krishna Polu, Andrea Uscinski, Gerald B Appel, Ronald J Falk, Avi Katz, Salah Al-Waheeb, Bernard S Kaplan, George Jerums, Judy Savige, Jennifer Harmon, Kang Zhang, Gary C Curhan, Martin R Pollak

Journal article  |  2008  |  BMC Nephrology

The effect of resistance training on functional capacity and quality of life in individuals with high and low numbers of metabolic risk factors

Itamar Levinger, Craig Goodman, David L Hare, George Jerums, Steve Selig

Journal article  |  2007  |  Diabetes Care

The accuracy of cystatin C and commonly used creatinine-based methods for detecting moderate and mild chronic kidney disease in diabetes

RJ MacIsaac, C Tsalamandris, MC Thomas, E Premaratne, S Panagiotopoulos, TJ Smith, A Poon, MA Jenkins, SI Ratnaike, DA Power, G Jerums

Journal article  |  2007  |  Diabetic Medicine

Management of Acute Illness in Adults with Type 1 Diabetes

R MACISAAC, G JERUMS

Journal article  |  2007  |  Diabetes Management

Measuring renal function in subjects with diabetes

R MACISAAC, G JERUMS

Journal article  |  2007  |  Clinical Chemistry and Laboratory Medicine

The epidemiology of hemoglobin levels in patients with type 2 diabetes

Merlin C Thomas, Con Tsalamandris, Richard J Maclsaac, George Jerums

Journal article  |  2006  |  American Journal of Kidney Diseases

Urine drug testing in an athlete leads to the diagnosis of unsuspected mediastinal germ cell tumor

Andrew E Newcomb, C Peter Clarke, Cherie Y Chiang, George Jerums

Journal article  |  2006  |  The Journal of Thoracic and Cardiovascular Surgery

Is nonalbuminuric renal insufficiency in type 2 diabetes related to an increase in intrarenal vascular disease?

Richard J MacIsaac, Sianna Panagiotopoulos, Karen J McNeil, Trudy J Smith, Con Tsalamandris, Huming Hao, P Geoffrey Matthews, Merlin C Thomas, David A Power, George Jerums

Journal article  |  2006  |  Diabetes Care

Estimating glomerular filtration rate in diabetes: a comparison of cystatin-C- and creatinine-based methods

RJ MacIsaac, C Tsalamandris, MC Thomas, E Premaratne, S Panagiotopoulos, TJ Smith, A Poon, MA Jenkins, SI Ratnaike, DA Power, G Jerums

Journal article  |  2006  |  Diabetologia

Estimating glomerular filtration rate in diabetes: a comparison of cystatin-C- and creatinine-based methods

RJ MacIsaac, C Tsalamandris, MC Thomas, E Premaratne, S Panagiotopoulos, TJ Smith, A Poon, MA Jenkins, SI Ratnaike, DA Power, G Jerums

Journal article  |  2006  |  Diabetologia

Is nonalbuminuric renal insufficiency in type 2 diabetes related to an increase in intrarenal vascular disease?

Richard J MacIsaac, Sianna Panagiotopoulos, Karen J McNeil, Trudy J Smith, Con Tsalamandris, Huming Hao, P Geoffrey Matthews, Merlin C Thomas, David A Power, George Jerums

Journal article  |  2006  |  Diabetes Care

OBJECTIVE: To investigate the role of intrarenal vascular disease in the pathogenesis of nonalbuminuric renal insufficiency in typ..

Functional erythropoietin deficiency in patients with Type 2 diabetes and anaemia

MC Thomas, C Tsalamandris, R MacIsaac, G Jerums

Journal article  |  2006  |  Diabetic Medicine

Anemia and Diabetic Nephropathy

G JERUMS, R MACISAAC, S PANAGIOTOPOULOS, undefined thomas

Book Chapter  |  2006

Podocytes and Diabetic Nephropathy

G JERUMS, S PANAGIOTOPOULOS, R MACISAAC

Book Chapter  |  2006

Urine drug testing in an athlete leads to the diagnosis of unsuspected mediastinal germ cell tumor

E newcomb, C clarke, C CHIANG, G JERUMS

Journal article  |  2006  |  The Journal of Thoracic and Cardiovascular Surgery

Diastolic dysfunction is associated with anaemia in patients with Type II diabetes

Piyush M Srivastava, Merlin C Thomas, Paul Calafiore, Richard J MacIsaac, George Jerums, Louise M Burrell

Journal article  |  2006  |  Clinical Science

Anaemia is common in patients with diabetes and associated with an increased risk of diabetic complications. Although the role of ..

Diastolic dysfunction is associated with anaemia in patients with Type II diabetes

PM Sristava, MC Thomas, P Calafiore, RJ MacIsaac, G Jerums, LM Burrell

Journal article  |  2006  |  Clinical Science

Pathogenesis of Nephropathy

G JERUMS, R MACISAAC

Journal article  |  2006  |  Diabetes Management Journal

Renal hyperfiltration in type 2 diabetes: effect of age-related decline in glomerular filtration rate

E Premaratne, RJ MacIsaac, C Tsalamandris, S Panagiotopoulos, T Smith, G Jerums

Journal article  |  2005  |  Diabetologia

Androgenic correlates of genetic variation in the gene encoding 5 alpha-reductase type 1

JA Ellis, S Panagiotopoulos, A Akdeniz, G Jerums, SB Harrap

Journal article  |  2005  |  Journal of Human Genetics

Albuminuric and non-albuminuric pathways to renal impairment in diabetes.

RJ Macisaac, G Jerums

Journal article  |  2005  |  Minerva Endocrinologica

Traditionally, microvascular disease resulting in a glomerulopathy and an increase in albumin excretion rate (AER) is believed to ..

Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy

JM Forbes, SR Thorpe, V Thallas-Bonke, J Pete, MC Thomas, ER Deemer, S Bassal, A El-Osta, DM Long, S Panagiotopoulos, G Jerums, TM Osicka, ME Cooper

Journal article  |  2005  |  Journal of the American Society of Nephrology

Increased tubular organic ion clearance following chronic ACE inhibition in patients with type 1 diabetes

MC Thomas, G Jerums, C Tsalamandris, R MacIsaac, S Panagiotopoulos, ME Cooper

Journal article  |  2005  |  Kidney International

Anemia with impaired erythropoietin response in diabetic patients

MC Thomas, ME Cooper, C Tsalamandris, R MacIsaac, G Jerums

Journal article  |  2005  |  Archives of Internal Medicine

Anaemia in diabetes: an emerging complication of microvascular disease.

Merlin Thomas, Con Tsalamandris, Richard MacIsaac, George Jerums

Journal article  |  2005  |  Current Diabetes Reviews

Diabetes as the dominant cause of ESRD is also the major cause of renal anaemia. However, most patients with diabetic kidney disea..

How long before I will need dialysis?

G JERUMS, S PANAGIOTOPOULOS, R MACISAAC

Conference Proceedings  |  2005  |  International Diabetes Federation

Low-molecular weight advanced glycation end products: Markers of tissue AGE accumulation and more?

MC Thomas, JM Forbes, R MacIsaac, G Jerums, ME Cooper

Journal article  |  2005  |  Annals of The New York Academy of Sciences

Long-term renoprotection by perindopril or nifedipine in non-hypertensive patients with Type 2 diabetes and microalbuminuria

G Jerums, TJ Allen, DJ Campbell, ME Cooper, RE Gilbert, JJ Hammond, RC O'Brien, J Raffaele, C Tsalamandris

Journal article  |  2004  |  Diabetic Medicine

Low-molecular-weight AGEs are associated with GFR and anemia in patients with type 2 diabetes

MC Thomas, C Tsalamandris, R MacIsaac, T Medley, B Kingwell, ME Cooper, G Jerums

Journal article  |  2004  |  Kidney International

Anemia in patients with type 1 diabetes

MC Thomas, RJ MacIsaac, C Tsalamandris, L Molyneaux, I Goubina, G Fulcher, D Yue, G Jerums

Journal article  |  2004  |  Journal of Clinical Endocrinology & Metabolism

Interactions between angiotensin II and NF-kappa B-dependent pathways in modulating macrophage infiltration in experimental diabetic nephropathy

FTH Lee, ZM Cao, DM Long, S Panagiotopoulos, G Jerums, ME Cooper, JM Forbes

Journal article  |  2004  |  Journal of the American Society of Nephrology

Thiazolidinediones and congestive heart failure - exacerbation or new onset of left ventricular dysfunction?

PM Srivastava, P Calafiore, RJ MacIsaac, DL Hare, G Jerums, LM Burrell

Journal article  |  2004  |  Diabetic Medicine

Elevated iron indices in patients with diabetes

MC Thomas, RJ MacIsaac, C Tsalamandris, G Jerums

Journal article  |  2004  |  Diabetic Medicine

The burden of anaemia in type 2 diabetes and the role of nephropathy: a cross-sectional audit

MC Thomas, RJ MacIsaac, C Tsalamandris, L Molyneaux, I Goubina, G Fulcher, D Yue, G Jerums

Journal article  |  2004  |  Nephrology, Dialysis, Transplantation

High prevalence of immunounreactive albumin in urine from diabetic patients with a low glomerular filtration rate and normoalbuminuria

TM Osicka, RJ MacIsaac, G Jerums, WD Comper

Journal article  |  2004  |  Diabetes Care

High Prevalence of Immunounreactive Albumin in Urine From Diabetic Patients With a Low Glomerular Filtration Rate and Normoalbuminuria

TM Osicka, RJ MacIsaac, G Jerums, WD Comper

Journal article  |  2004  |  Diabetes Care

Clinical indications of thiazolidinediones

RJ MacIsaac, G Jerums

Journal article  |  2004  |  Australian Prescriber

Earlier detection of micro albuminuria in diabetic patients using a new urinary albumin assay

WD Comper, TM Osicka, M Clark, RJ MacIsaac, G Jerums

Journal article  |  2004  |  Kidney International

Renal processing of serum proteins in an albumin-deficient environment: an in vivo study of glomerulonephritis in the Nagase analbuminaemic rat

TM Osicka, KJ Strong, DJ Nikolic-Paterson, RC Atkins, G Jerums, WD Comper

Journal article  |  2004  |  Nephrology, Dialysis, Transplantation

Differences in urinary albumin detected by four immunoassays and high-performance liquid chromatography

WD Comper, G Jerums, TM Osicka

Journal article  |  2004  |  Clinical Biochemistry

New insights into the significance of microalbuminuria

RJ Maclsaac, G Jerums, ME Cooper

Journal article  |  2004  |  Current Opinion in Nephrology and Hypertension

Microalbuminuria and GFR in type 1 and type 2 diabetes

G JERUMS, S PANAGIOTOPOULOS, RJ MACISAAC

Book Chapter  |  2004

Superior renoprotective effects of combination therapy with ACE and AGE inhibition in the diabetic spontaneously hypertensive rat

BJ Davis, JM Forbes, MC Thomas, G Jerums, WC Burns, H Kawachi, TJ Allen, ME Cooper

Journal article  |  2004  |  Diabetologia

Nonalbuminuric renal insufficiency in type 2 diabetes

R MacIsaac, C Tsalamandris, S Panagiotopoulos, T Smith, K McNeil, G Jerums

Journal article  |  2004  |  Diabetes Care

Additive effects of hypertension and diabetes on renal cortical expression of PKC-alpha and -epsilon, and alpha-tubulin but not PKC-beta(1) and -beta(2)

TM Osicka, LM Russo, ML Qiu, GC Brammar, V Thallas, JM Forbes, WD Comper, G Jerums

Journal article  |  2003  |  Journal of Hypertension

Endocrinology - 3: Preventing complications of diabetes

KL Bate, G Jerums

Journal article  |  2003  |  Medical Journal of Australia

Deficiency in the detection of microalbuminuria by urinary dipstick in diabetic patients

WD Comper, G Jerums, TM Osicka

Journal article  |  2003  |  Diabetes Care

Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease

G Jerums, S Panagiotopoulos, J Forbes, T Osicka, M Cooper

Journal article  |  2003  |  Archives of Biochemistry and Biophysics

Urinary Connective Tissue Growth Factor Excretion in Patients With Type 1 Diabetes and Nephropathy

RE Gilbert, A Akdeniz, S Weitz, WR Usinger, C Molineaux, SE Jones, RG Langham, G Jerums

Journal article  |  2003  |  Diabetes Care

The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.

Josephine M Forbes, Vicki Thallas, Merlin C Thomas, Hank W Founds, Wendy C Burns, George Jerums, Mark E Cooper

Journal article  |  2003  |  The FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Renal accumulation of advanced glycation end products (AGEs) has been linked to the progression of diabetic nephropathy. Cleavage ..

Urinary connective tissue growth factor excretion in patients with type 1 diabetes and nephropathy

RE Gilbert, A Akdeniz, S Weitz, WR Usinger, C Molineaux, SE Jones, RG Langham, G Jerums

Journal article  |  2003  |  Diabetes Care

Ramipril prevents microtubular changes in proximal tubules from streptozotocin diabetic rats

TM Osicka, JM Forbes, V Thallas, GC Brammar, G Jerums, WD Comper

Journal article  |  2003  |  Nephrology

The Amino-terminal Domains of the Ezrin, Radixin, and Moesin (ERM) Proteins Bind Advanced Glycation End Products, an Interaction That May Play a Role in the Development of Diabetic Complications

E Anne McRobert, Marisa Gallicchio, George Jerums, Mark E Cooper, Leon A Bach

Journal article  |  2003  |  Journal of Biological Chemistry

The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications

EA McRobert, M Gallicchio, G Jerums, ME Cooper, LA Bach

Journal article  |  2003  |  Journal of Biological Chemistry

The breakdown of pre-existing advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes

JM Forbes, V Thallas, MC Thomas, HW Founds, WC Burns, G Jerums, ME Cooper

Journal article  |  2003  |  FASEB Journal

Reduced tubular cation transport in diabetes: Prevented by ACE inhibition

MC Thomas, C Tikellis, WC Burns, V Thallas, JM Forbes, ZM Cao, TM Osicka, LM Russo, G Jerums, H Ghabrial, ME Cooper, P Kantharidis

Journal article  |  2003  |  Kidney International

Unrecognized anemia in patients with diabetes - A cross-sectional survey

MC Thomas, R MacIsaac, C Tsalamandris, D Power, G Jerums

Journal article  |  2003  |  Diabetes Care

Losartan [2]

G Jerums

Journal article  |  2003  |  Drugs

Renal processing of albumin in diabetes and hypertension in rats

LM Russo, TM Osicka, GC Brammar, R Candido, G Jerums, WD Comper

Journal article  |  2003  |  American Journal of Nephrology

The effect of ramipril on albumin excretion in diabetes and hypertension: the role of increased lysosomal activity and decreased transforming growth factor-beta expression

LM Russo, GC Brammar, G Jerums, WD Comper, TM Osicka

Journal article  |  2003  |  Journal of Hypertension

High prevalence of immuno-unreactive intact albumin in urine of diabetic patients.

Wayne D Comper, Tanya M Osicka, George Jerums

Journal article  |  2003  |  American Journal of Kidney Diseases

BACKGROUND: Intact albumin in urine may exist in two forms, immunoreactive and immuno-unreactive. Previous estimates of albuminuri..

Preventing complications of diabetes

G JERUMS, KL BATE

Journal article  |  2003  |  Medical Journal of Australia

Diabetic nephropathy: epidemiology and clinical description

G JERUMS, S PANAGIOTOPOULOS, RJ MACISAAC

Book Chapter  |  2003

Reversible angiotensin II-mediated albuminuria in rat kidneys is dynamically associated with cytoskeletal organization.

Steven P Clavant, Josephine M Forbes, Vicki Thallas, Tanya M Osicka, George Jerums, Wayne D Comper

Journal article  |  2003  |  Nephron

Angiotensin II (ANG II) is intimately involved in normal renal function, and is estimated to exist at a normal physiological range..

Mixed diabetic ketoacidosis and hyperosmolarity

RJ MACISAAC, G JERUMS

Book Chapter  |  2003

Seizures after alendronate

RJ Maclsaac, E Seeman, G Jerums

Journal article  |  2002  |  JRSM

Erratum: Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy (Diabetes (2000) 51 (3274-3282))

JM Forbes, ME Cooper, V Thallas, WC Burns, MC Thomas, GC Brammar, F Lee, SL Grant, LA Burrell, G Jerums, TM Osicka

Journal article  |  2002  |  Diabetes

Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy

JM Forbes, ME Cooper, V Thallas, WC Burns, MC Thomas, GC Brammar, F Lee, SL Grant, LA Burrell, G Jerums, TM Osicka

Journal article  |  2002  |  Diabetes

The influence of diabetes mellitus and hyperglycaemia on stroke incidence and outcome

TA Baird, MW Parsons, PA Barber, KS Butcher, PM Desmond, BM Tress, PG Colman, G Jerums, BR Chambers, SM Davis

Journal article  |  2002  |  Journal of Clinical Neuroscience

Diabetic muscle infarction

RJ MacIsaac, G Jerums, L Scurrah

Journal article  |  2002  |  Medical Journal of Australia

Influence of age on the presentation and outcome of acidotic and hyperosmolar diabetic emergencies

RJ MacIsaac, LY Lee, KJ McNeil, C Tsalamandris, G Jerums

Journal article  |  2002  |  Internal Medicine Journal

Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti-proteinuric therapies

DJ Kelly, P Aaltonen, AJ Cox, JR Rumble, R Langham, S Panagiotopoulos, G Jerums, H Holthofer, RE Gilbert

Journal article  |  2002  |  Nephrology, Dialysis, Transplantation

Albumin to creatinine ratio: A screening test with limitations

CA Houlihan, C Tsalamandris, A Akdeniz, G Jerums

Journal article  |  2002  |  American Journal of Kidney Diseases

Urinary transforming growth factoro-beta excretion in patients with hypertension, type 2 diabetes, and elevated albumin excretion rate - Effects of angiotensin receptor blockade and sodium restriction

CA Houlihan, A Akdeniz, C Tsalamandris, ME Cooper, G Jerums, RE Gilbert

Journal article  |  2002  |  Diabetes Care

Modulation of nephrin in the diabetic kidney: association with systemic hypertension and increasing albuminuria

JM Forbes, F Bonnet, LM Russo, WC Burns, ZM Cao, R Candido, H Kawachi, TJ Allen, ME Cooper, G Jerums, TM Osicka

Journal article  |  2002  |  Journal of Hypertension

A low-sodium diet potentiates the effects of losartan in type 2 diabetes

CA Houlihan, T Allen, AL Baxter, S Panangiotopoulos, DJ Casley, ME Cooper, G Jerums

Journal article  |  2002  |  Diabetes Care

Renal protection by angiotensin II receptor antagonists in patients with type 2 diabetes.

Roger E Peverill

Journal article  |  2002  |  Medical Journal of Australia

Albuminuria in hypertension is linked to altered lysosomal activity and TGF-beta 1 expression

LM Russo, TM Osicka, F Bonnet, G Jerums, WD Comper

Journal article  |  2002  |  Hypertension

Urinary transforming growth factor-β excretion in patients with hypertension, type 2 diabetes, and elevated albumin excretion rate

CA HOULIHAN, ME COOPER, A AKDENIZ, G JERUMS, C TSALAMANDRIS, RE GILBERT

Journal article  |  2002  |  Diabetes Care

Treatment of dyslipidaemia in the elderly

RJ MacIsaac, G Jerums

Journal article  |  2002  |  Journal of Pharmacy Practice and Research

Diabetic muscle infarction

RJ MACISAAC, G JERUMS, L SCURRAH

Journal article  |  2002  |  Medical Journal of Australia

Treatment of microalbuminuria in patients with type 2 diabetes mellitus.

George Jerums, Richard J MacIsaac

Journal article  |  2002  |  Treatments in Endocrinology

The incidence of type 2 diabetes mellitus is increasing world-wide, and is now one of the leading causes of end-stage renal diseas..

Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)

MD Oldfield, LA Bach, JM Forbes, D Nikolic-Paterson, A McRobert, V Thallas, RC Atkins, T Osicka, G Jerums, ME Cooper

Journal article  |  2001  |  Journal of Clinical Investigation

Urinary transforming growth factor-beta in patients with diabetic nephropathy: implications for the pathogenesis of tubulointerstitial pathology

RE Gilbert, A Akdeniz, TJ Allen, G Jerums

Journal article  |  2001  |  Nephrology, Dialysis, Transplantation

Renal protection by angiotensin II receptor antagonists in patients with type 2 diabetes

G Jerums, ME Cooper, RE Gilbert, RC Atkins

Journal article  |  2001  |  Medical Journal of Australia

Aminoguanidine ameliorates overexpression of prosclerotic growth factors and collagen deposition in experimental diabetic nephropathy

DJ Kelly, RE Gilbert, AJ Cox, T Soulis, GT Jerums, ME Cooper

Journal article  |  2001  |  Journal of the American Society of Nephrology

Immuno-unreactive albumin excretion increases in streptozotocin diabetic rats

KA Greive, GA Eppel, S Reeve, AI Smith, G Jerums, WD Comper

Journal article  |  2001  |  American Journal of Kidney Diseases

Pathogenesis and intervention strategies in diabetic retinopathy

DY Yu, SJ Cringle, EN Su, PK Yu, G Jerums, ME Cooper

Journal article  |  2001  |  Clinical and Experimental Ophthalmology

Long-term comparison between perindopril and nifedipine in normotensive patients with type 1 diabetes and microalbuminuria

G Jerums, TJ Allen, DJ Campbell, ME Cooper, RE Gilbert, JJ Hammond, J Raffaele, C Tsalamandris

Journal article  |  2001  |  American Journal of Kidney Diseases

Should all patients with type 1 diabetes mellitus and microalbuminuria receive angiotensin-converting enzyme inhibitors? A meta-analysis of individual patient data.

undefined ACE Inhibitors in Diabetic Nephropathy Trialist Group

Journal article  |  2001  |  Annals of Internal Medicine

PURPOSE: To determine whether response of albumin excretion rate to angiotensin-converting enzyme (ACE) inhibitors has a threshold..

Ramipril and aminoguanidine restore renal lysosomal processing in streptozotocin diabetic rats

TM Osicka, Z Kiriazis, LM Pratt, G Jerums, WD Comper

Journal article  |  2001  |  Diabetologia

Renoprotective effects of a novel inhibitor of advanced glycation

JM Forbes, T Soulis, V Thallas, S Panagiotopoulos, DM Long, S Vasan, D Wagle, G Jerums, ME Cooper

Journal article  |  2001  |  Diabetologia

Angiotensin converting enzyme inhibition reduces retinal overexpression of vascular endothelial growth factor and hyperpermeability in experimental diabetes

RE Gilbert, DJ Kelly, AJ Cox, JL Wilkinson-Berka, JR Rumble, T Osicka, S Panagiotopoulos, V Lee, EC Hendrich, G Jerums, ME Cooper

Journal article  |  2000  |  Diabetologia

Albuminuria in patients with type 1 diabetes is directly linked to changes in the lysosome-mediated degradation of albumin during renal passage

TM Osicka, CA Houlihan, JG Chan, G Jerums, WD Comper

Journal article  |  2000  |  Diabetes

Measurement of iohexol by capillary electrophoresis: minimizing practical problems encountered

MA Jenkins, C Houlihan, S Ratnaike, G Jerums, JD Parkin

Journal article  |  2000  |  Annals of Clinical Biochemistry: An international journal of biochemistry and laboratory medicine

Proteolysis of insulin-like growth factor-binding protein-3 is increased in urine from patients with diabetic nephropathy

M Shinada, A Akdeniz, S Panagiotopoulos, G Jerums, LA Bach

Journal article  |  2000  |  Journal of Clinical Endocrinology and Metabolism

Prevention of albuminuria by aminoguanidine or ramipril in streptozotocin-induced diabetic rats is associated with the normalization of glomerular protein kinase C

TM Osicka, YX Yu, S Panagiotopoulos, SP Clavant, Z Kiriazis, RN Pike, LM Pratt, LM Russo, BE Kemp, WD Comper, G Jerums

Journal article  |  2000  |  Diabetes

A comparison of the plasma disappearance of iohexol and Tc-99m-DTPA for the measurement of glomerular filtration rate (GFR) in diabetes

C Houlihan, A Scott, M Jenkins, D Parkin, T Osicka, G Jerums

Journal article  |  1999  |  Australian and New Zealand Journal of Medicine

A novel inhibitor of advanced glycation end-product formation inhibits mesenteric vascular hypertrophy in experimental diabetes

T Soulis, S Sastra, V Thallas, SB Mortensen, M Wilken, JT Clausen, OJ Bjerrum, H Petersen, J Lau, G Jerums, E Boel, ME Cooper

Journal article  |  1999  |  Diabetologia

Effect of diabetes and aminoguanidine therapy on renal advanced glycation end-product binding

S Youssef, DT Nguyen, T Soulis, S Panagiotopoulos, G Jerums, ME Cooper

Journal article  |  1999  |  Kidney International

Effects of insulin therapy and glycemic control on distribution of HDL alpha and pre-beta subfractions in non insulin-dependent diabetic subjects

T Sasahara, G Jerums, P Nestel

Journal article  |  1999  |  Nutrition, Metabolism and Cardiovascular Diseases

Localization of secreted protein acidic and rich in cysteine (SPARC) expression in the rat eye

RE Gilbert, AJ Cox, DJ Kelly, JL Wilkinson-Berka, EH Sage, G Jerums, ME Cooper

Journal article  |  1999  |  Connective Tissue Research

Differences in renal outcomes with ACE inhibitors in type 1 and type 2 diabetic patients: Possible explanations

G Jerums

Journal article  |  1998  |  Mineral and Electrolyte Metabolism

Renal expression of transforming growth factor-beta inducible gene-h3 (beta ig-h3) in normal and diabetic rats

RE Gilbert, JL Wilkinson-Berka, DW Johnson, A Cox, T Soulis, LL Wu, DJ Kelly, G Jerums, CA Pollock, ME Cooper

Journal article  |  1998  |  Kidney International

Alterations in renal degradation of albumin in early experimental diabetes in the rat: a new factor in the mechanism of albuminuria

MJ Burne, S Panagiotopoulos, G Jerums, WD Comper

Journal article  |  1998  |  Clinical Science

Long-term intraindividual variability of serum lipids in patients with type I and type II diabetes

C Tsalamandris, S Panagiotopoulos, TJ Allen, L Waldrip, B Van Gaal, I Goodall, G Jerums

Journal article  |  1998  |  Journal of Diabetes and its Complications

Anomalous decrease in dextran sulfate clearance in the diabetic rat kidney.

MJ Burne, Y Adal, N Cohen, S Panagiotopoulos, G Jerums, WD Comper

Journal article  |  1998  |  American Journal of Physiology-Renal Physiology

The anomalous increase in charge selectivity as previously observed with reduced dextran sulfate clearances in diabetic rats (L. D..

Expression of transforming growth factor-beta 1 and type IV collagen in the renal tubulointerstitium in experimental diabetes - Effects of ACE inhibition

RE Gilbert, A Cox, LL Wu, TJ Allen, UL Hulthen, G Jerums, ME Cooper

Journal article  |  1998  |  Diabetes

Early nephropathy predicts vision-threatening retinal disease in patients with type I diabetes mellitus

RE Gilbert, C Tsalamandris, TJ Allen, D Colville, G Jerums

Journal article  |  1998  |  Journal of the American Society of Nephrology

Aminoguanidine has an anti-atherogenic effect in the cholesterol-fed rabbit

S Panagiotopoulos, RC O'Brien, R Bucala, ME Cooper, G Jerums

Journal article  |  1998  |  Atherosclerosis

Fractional clearance of albumin is influenced by its degradation during renal passage

TM Osicka, S Panagiotopoulos, G Jerums, WD Comper

Journal article  |  1997  |  Clinical Science

Why is proteinuria such an important risk factor for progression in clinical trials?

G Jerums, S Panagiotopoulos, C Tsalamandris, TJ Allen, RE Gilbert, WD Comper

Conference Proceedings  |  1997  |  Kidney International, Supplement

Relative contributions of advanced glycation and nitric oxide synthase inhibition to aminoguanidine-mediated renoprotection in diabetic rats

T Soulis, ME Cooper, S Sastra, V Thallas, S Panagiotopoulos, OJ Bjerrum, G Jerums

Journal article  |  1997  |  Diabetologia

Diabetic vascular complications

ME Cooper, RE Gilbert, G Jerums

Journal article  |  1997  |  Clinical and Experimental Pharmacology and Physiology

A multicenter, double-blind, one-year study comparing safety and efficacy of Atorvastatin versus Simvastatin in patients with hypercholesterolemia

A Dart, G Jerums, G Nicholson, M dEmden, I HamiltonCraig, G Tallis, J Best, M West, D Sullivan, P Bracs, D Black

Journal article  |  1997  |  The American Journal of Cardiology

Increased epidermal growth factor in experimental diabetes related kidney growth in rats

RE Gilbert, A Cox, PG McNally, LL Wu, M Dziadek, ME Cooper, G Jerums

Journal article  |  1997  |  Diabetologia

Vascular hypertrophy in experimental diabetes - Role of advanced glycation end products

JR Rumble, ME Cooper, T Soulis, A Cox, L Wu, S Youssef, M Jasik, G Jerums, RE Gilbert

Journal article  |  1997  |  Journal of Clinical Investigation

Detection of microalbuminuria in diabetic patients by urinary dipstick.

RE Gilbert, A Akdeniz, G Jerums

Journal article  |  1997  |  Diabetes Research and Clinical Practice

The present study was undertaken to determine the usefulness of a new, sensitive urinary dipstick, Micral-Test II (Boehringer-Mann..

Salt restriction reduces hyperfiltration, renal enlargement, and albuminuria in experimental diabetes

TJ Allen, MJ Waldron, D Casley, G Jerums, ME Cooper

Journal article  |  1997  |  Diabetes

Salt restriction reduces hyperfiltration, renal enlargement, and albuminuria in experimental diabetes.

TJ Allen, MJ Waldron, D Casley, G Jerums, ME Cooper

Journal article  |  1997  |  Diabetes

The effects of dietary salt restriction on the renin-angiotensin system, glomerular filtration rate (GFR), renal size, and albumin..

Serum total renin is increased before microalbuminuria in diabetes

TJ Allen, ME Cooper, RE Gilbert, J Winikoff, SL Skinner, G Jerums

Journal article  |  1996  |  Kidney International

Effects of aminoguanidine in preventing experimental diabetic nephropathy are related to the duration of treatment.

T Soulis, ME Cooper, D Vranes, R Bucala, G Jerums

Journal article  |  1996  |  Kidney International

It has been postulated that the accumulation of advanced glycation end products (AGEs) in the kidney is important in the pathogene..

Interlaboratory variation of GHb assays in Victoria, Australia.

RE Gilbert, I Goodall, V Young, G Jerums

Journal article  |  1996  |  Diabetes Care

OBJECTIVE: To determine the extent of interlaboratory variation and accuracy in the measurement of glycated hemoglobin (GHb). RESE..

Primary prevention of stroke.

A Martinez-Riera, F Santolaria-Fernandez, E Gonzalez-Reimers

Journal article  |  1996  |  New England Journal of Medicine

Atrial natriuretic peptide and plasma renin levels in assessment of mineralocorticoid replacement in Addison's disease.

N Cohen, R Gilbert, A Wirth, D Casley, G Jerums

Journal article  |  1996  |  Journal of Clinical Endocrinology and Metabolism

Assessment of mineralocorticoid replacement therapy in Addison's disease relies on clinical features and laboratory measurements, ..

Aminoguanidine prevents retinal but not glomerular capillary basement membrane thickening in experimental diabetes

CS Mao, N Carroll, S Panagiotopoulos, T Soulis, T Lim Joon, ME Cooper, G Jerums, H Taylor

Journal article  |  1996  |  Investigative Ophthalmology and Visual Science

Organ specificity of antihypertensive therapy on ocular albumin vascular clearance and albuminuria in the hypertensive diabetic rat

T Gin, TL Joon, S Panagiotopoulos, M Cooper, H Taylor, G Jerums

Journal article  |  1996  |  Investigative Ophthalmology and Visual Science

Effects of insulin on body composition in patients with insulin-dependent and non-insulin-dependent diabetes

A Sinha, C Formica, C Tsalamandris, S Panagiotopoulos, E Hendrich, M DeLuise, E Seeman, G Jerums

Journal article  |  1996  |  Diabetic Medicine

Extracellular matrix, growth factors and their interactions in the pathogenesis of diabetic kidney disease

RE Gilbert, ME Cooper, G Jerums

Journal article  |  1996  |  Nephrology

Diabetes and hypertension: prognostic and therapeutic considerations.

RE Gilbert, G Jerums, ME Cooper

Journal article  |  1995  |  Blood Pressure

Hypertension and diabetes are common disorders which frequently co-exist. Both are risk factors for atherosclerotic vascular disea..

Prevention of diabetic renal disease with special reference to microalbuminuria.

CE Mogensen, WF Keane, PH Bennett, G Jerums, HH Parving, P Passa, MW Steffes, GE Striker, GC Viberti

Journal article  |  1995  |  The Lancet

SPARC gene expression is reduced in early diabetes-related kidney growth.

RE Gilbert, PG McNally, A Cox, M Dziadek, J Rumble, ME Cooper, G Jerums

Conference Proceedings  |  1995  |  Kidney International

Renal enlargement is a characteristic feature of diabetes in humans and experimental animals that may predict subsequent renal dis..

Angiotensin-converting enzyme (ACE) gene polymorphism in type II diabetic patients with increased albumin excretion rate

S Panagiotopoulos, TJ Smith, GP Aldred, EJ Baker, CJ Jacklin, G Jerums

Conference Proceedings  |  1995  |  Journal of Diabetes and its Complications

Extracellular matrix and its interactions in the diabetic kidney: a molecular biological approach.

RE Gilbert, A Cox, M Dziadek, ME Cooper, G Jerums

Journal article  |  1995  |  Journal of Diabetes and its Complications

Increased extracellular matrix (ECM) is the ultrastructural hallmark of diabetic microangiopathy. Its accumulation within the kidn..

Natural history of early diabetic nephropathy: what are the effects of therapeutic intervention? Melbourne Diabetic Nephropathy Study Group.

G Jerums, TJ Allen, RE Gilbert, J Hammond, ME Cooper, DJ Campbell, J Raffaele

Journal article  |  1995  |  Journal of Diabetes and its Complications

Several studies have shown that lowering of blood pressure slows the rate of progression of diabetic renal disease. Some placebo-c..

Long-term efficacy and tolerability of simvastatin in a large cohort of elderly hypercholesterolemic patients.

PJ Lansberg, YB Mitchel, D Shapiro, JJ Kastelein, R Altman, G Jerums, K Bolzano, S Giannini, J Davignon, P DeWailly

Journal article  |  1995  |  Atherosclerosis

The long-term efficacy and tolerability of simvastatin, a 3-hydroxy-3-methylglutaryl-co-enzyme A (HMG-CoA) reductase inhibitor, wa..

THE RELATIVE ROLES OF ADVANCED GLYCATION, OXIDATION AND ALDOSE REDUCTASE INHIBITION IN THE DEVELOPMENT OF EXPERIMENTAL DIABETIC NEPHROPATHY IN THE SPRAGUE-DAWLEY RAT

T SOULISLIPAROTA, ME COOPER, M DUNLOP, G JERUMS

Journal article  |  1995  |  Diabetologia

DIABETIC DYSLIPIDEMIA - AUSTRALIAN-DIABETES-SOCIETY POSITION-STATEMENT

JD BEST, G JERUMS, HH NEWNHAM, RC OBRIEN

Journal article  |  1995  |  Medical Journal of Australia

Angiotensin converting enzyme inhibitors and diabetic renal disease. ACE inhibitors may prevent progression from incipient to clinical nephropathy.

RE Gilbert, G Jerums

Journal article  |  1994  |  Medical Journal of Australia

Complementary effects of pravastatin and nicotinic acid in the treatment of combined hyperlipidaemia in diabetic and non-diabetic patients.

C Tsalamandris, S Panagiotopoulos, A Sinha, ME Cooper, G Jerums

Journal article  |  1994  |  European Journal of Cardiovascular Prevention & Rehabilitation

BACKGROUND: Given that treatment with a single drug is frequently unsuccessful in patients with combined hyperlipidaemia, there is..

MICROALBUMINURIA IN DIABETES

G JERUMS, M COOPER, R GILBERT, R OBRIEN, J TAFT

Journal article  |  1994  |  Medical Journal of Australia

Day-night blood pressure variation in normotensive, normoalbuminuric type I diabetic subjects. Dippers and non-dippers.

R Gilbert, P Phillips, C Clarke, G Jerums

Journal article  |  1994  |  Diabetes Care

OBJECTIVE: To examine day-night blood pressure (BP) variation in normotensive, normoalbuminuric subjects with type I diabetes and ..

MICROALBUMINURIA - PROGNOSTIC AND THERAPEUTIC IMPLICATIONS IN DIABETES-MELLITUS

RE GILBERT, ME COOPER, PG MCNALLY, RC OBRIEN, J TAFT, G JERUMS

Journal article  |  1994  |  Diabetic Medicine

Thirty years following the development of the first radioimmunoassay for albumin, microalbuminuria is widely acknowledged as an im..

Progressive decline in renal function in diabetic patients with and without albuminuria.

C Tsalamandris, TJ Allen, RE Gilbert, A Sinha, S Panagiotopoulos, ME Cooper, G Jerums

Journal article  |  1994  |  Diabetes

This study describes patterns of progression of albuminuria and renal function in a subgroup of 40 patients from a total cohort of..