Nick Wilson

Targeting the Human βc Receptor Inhibits Contact Dermatitis in a Transgenic Mouse Model.

Kwok Ho Yip, Duncan McKenzie, Hayley S Ramshaw, Jessica Chao, Barbara J McClure, Elmar Raquet, Timo Kraushaar, Joachim Röder, Mhairi Maxwell, Monther Alhamdoosh, Andrew Hammet, Jia Hong Fong, Kathleen Zeglinski, Katherine Monaghan, Harshita Pant, Michele A Grimbaldeston, Gino Vairo, Nicholas J Wilson, Catherine M Owczarek, Timothy R Hercus, et al.

Journal article  |  2021  |  J Invest Dermatol

Allergic contact dermatitis (ACD) is a prevalent and poorly controlled inflammatory disease caused by skin infiltration of T cells..

Nasopharyngeal carriage of otitis media pathogens in infants receiving 10-valent non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10), 13-valent pneumococcal conjugate vaccine (PCV13) or a mixed primary schedule of both vaccines: A randomised controlled trial.

J Beissbarth, N Wilson, B Arrowsmith, MJ Binks, VM Oguoma, K Lawrence, A Llewellyn, EK Mulholland, M Santosham, PS Morris, HC Smith-Vaughan, AC Cheng, AJ Leach

Journal article  |  2021  |  Vaccine

BACKGROUND: Aboriginal children in Northern Australia have a high burden of otitis media, driven by early and persistent nasophary..

Interchangeability, immunogenicity and safety of a combined 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (Synflorix) and 13-valent-PCV (Prevenar13) schedule at 1-2-4-6 months: PREVIX_COMBO, a 3-arm randomised controlled trial.

Amanda Jane Leach, Edward Kim Mulholland, Mathuram Santosham, Paul John Torzillo, Peter McIntyre, Heidi Smith-Vaughan, Nicole Wilson, Beth Arrowsmith, Jemima Beissbarth, Mark D Chatfield, Victor M Oguoma, Paul Licciardi, Sue Skull, Ross Andrews, Jonathan Carapetis, Joseph McDonnell, Vicki Krause, Peter Stanley Morris

Journal article  |  2021  |  Vaccine X

Background: Aboriginal children living in remote communities are at high risk of early and persistent otitis media. Streptococcus ..

Should prioritising health interventions be informed by modelling studies? The case of cancer control in Aotearoa New Zealand

Nick Wilson, Leah Grout, Jennifer Summers, Amanda C Jones, Anja Mizdrak, Nhung Nghiem, Cristina Cleghorn, Tony Blakely

Journal article  |  2021  |  NEW ZEALAND MEDICAL JOURNAL

In this viewpoint, we suggest that policymakers should prioritise health interventions by using evidence around health gain, impac..

Cellular Microenvironment Stiffness Regulates Eicosanoid Production and Signaling Pathways

Asres Berhan, Trudi Harris, Jade Jaffar, Fernando Jativa, Shenna Langenbach, Ingrid Loennstedt, Monther Alhamdoosh, Milica Ng, Peter Lee, Glen Westall, Nick Wilson, Michael Wilson, Alastair G Stewart

Journal article  |  2020  |  AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pathological changes in the biomechanical environment are implicated in the progression of idiopathic pulmonary fibrosis (IPF). St..

Novel Therapies for Pneumonia-Associated Severe Asthma Phenotypes

Angelica Papanicolaou, Hao Wang, Catherine Satzke, Ross Vlahos, Nick Wilson, Steven Bozinovski

Journal article  |  2020  |  TRENDS IN MOLECULAR MEDICINE

Distinct asthma phenotypes are emerging from well-defined cohort studies and appear to be associated with a history of pneumonia. ..

Anti-βc mAb CSL311 inhibits human nasal polyp pathophysiology in a humanized mouse xenograft model.

Kwok Ho Yip, Nicholas J Wilson, Harshita Pant, Christopher L Brown, Samantha Busfield, Milica Ng, Monther Alhamdoosh, Naomi Woodman, Mark Schembri, Damon J Tumes, Gino Vairo, Angel F Lopez, Andrew D Nash, Michael J Wilson, Michele A Grimbaldeston, Catherine M Owczarek

Journal article  |  2020  |  Allergy

G-CSFR antagonism reduces neutrophilic inflammation during pneumococcal and influenza respiratory infections without compromising clearance.

Hao Wang, Christian Aloe, Nick Wilson, Steven Bozinovski

Journal article  |  2019  |  Sci Rep

Excessive neutrophilic inflammation can contribute to the pathogenesis of pneumonia. Whilst anti-inflammatory therapies such as co..

Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans

Jarny Choi, Tracey M Baldwin, Mae Wong, Jessica E Bolden, Kirsten A Fairfax, Erin C Lucas, Rebecca Cole, Christine Biben, Clare Morgan, Kerry A Ramsay, Ashley P Ng, Maria Kauppi, Lynn M Corcoran, Wei Shi, Nick Wilson, Michael J Wilson, Warren S Alexander, Douglas J Hilton, Carolyn A de Graaf

Journal article  |  2019  |  NUCLEIC ACIDS RESEARCH

During haematopoiesis, haematopoietic stem cells differentiate into restricted potential progenitors before maturing into the many..

A potential association between IL-3 and type I and III interferons in systemic lupus erythematosus

Shereen Oon, Katherine Monaghan, Milica Ng, Alberta Hoi, Eric Morand, Gino Vairo, Eugene Maraskovsky, Andrew D Nash, Ian P Wicks, Nicholas J Wilson

Journal article  |  2019  |  CLINICAL & TRANSLATIONAL IMMUNOLOGY

Objectives: Plasmacytoid dendritic cells (pDCs), through the production of type 1 interferons (IFNs) and other cytokines, are majo..