Nick Wilson

Type 2 immune polarization is associated with cardiopulmonary disease in preterm infants

Jason C Lao, Christine B Bui, Merrin A Pang, Steven X Cho, Ina Rudloff, Kirstin Elgass, Jan Schroder, Anton Maksimenko, Niamh E Mangan, Malcolm R Starkey, Elisabeth M Skuza, Yu BY Sun, Friederike Beker, Clare L Collins, Omar F Kamlin, Kai Konig, Atul Malhotra, Kenneth Tan, Christiane Theda, Morag J Young, et al.

Journal article  |  2022  |  SCIENCE TRANSLATIONAL MEDICINE

Postnatal maturation of the immune system is poorly understood, as is its impact on illnesses afflicting term or preterm infants, ..

Targeting the Human beta(c) Receptor Inhibits Contact Dermatitis in a Transgenic Mouse Model

Kwok Ho Yip, Duncan McKenzie, Hayley S Ramshaw, Jessica Chao, Barbara J McClure, Elmar Raquet, Timo Kraushaar, Joachim Roeder, Mhairi Maxwell, Monther Alhamdoosh, Andrew Hammet, Jia Hong Fong, Kathleen Zeglinski, Katherine Monaghan, Harshita Pant, Michele A Grimbaldeston, Gino Vairo, Nicholas J Wilson, Catherine M Owczarek, Timothy R Hercus, et al.

Journal article  |  2022  |  JOURNAL OF INVESTIGATIVE DERMATOLOGY

Allergic contact dermatitis (ACD) is a prevalent and poorly controlled inflammatory disease caused by skin infiltration of T cells..

Coagulation factor-XII induces interleukin-6 by primary lung fibroblasts: a role in idiopathic pulmonary fibrosis?

Jade Jaffar, Laura McMillan, Nick Wilson, Con Panousis, Charles Hardy, Hyun-Jung Cho, Karen Symons, Ian Glaspole, Glen Westall, Mae Wong

Journal article  |  2022  |  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The mechanisms driving idiopathic pulmonary fibrosis (IPF) remain undefined, however it is postulated that coagulation imbalances ..

Mechanisms of Li Leaching from a LiCO3 Based Primer / Topcoat Paint System

Alexander Glenn, Peter Visser, Tony Hughes, Shyama Ranade, Jamie Laird, Herman Terryn, Arjan Mol, Colin MacRae, Nicholas Wilson, Aaron Torpy

Journal article  |  2021  |  Microscopy and Microanalysis

Nasopharyngeal carriage of otitis media pathogens in infants receiving 10-valent non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10), 13-valent pneumococcal conjugate vaccine (PCV13) or a mixed primary schedule of both vaccines: A randomised controlled trial.

J Beissbarth, N Wilson, B Arrowsmith, MJ Binks, VM Oguoma, K Lawrence, A Llewellyn, EK Mulholland, M Santosham, PS Morris, HC Smith-Vaughan, AC Cheng, AJ Leach

Journal article  |  2021  |  Vaccine

BACKGROUND: Aboriginal children in Northern Australia have a high burden of otitis media, driven by early and persistent nasophary..

Interchangeability, immunogenicity and safety of a combined 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (Synflorix) and 13-valent-PCV (Prevenar13) schedule at 1-2-4-6 months: PREVIX_COMBO, a 3-arm randomised controlled trial.

Amanda Jane Leach, Edward Kim Mulholland, Mathuram Santosham, Paul John Torzillo, Peter McIntyre, Heidi Smith-Vaughan, Nicole Wilson, Beth Arrowsmith, Jemima Beissbarth, Mark D Chatfield, Victor M Oguoma, Paul Licciardi, Sue Skull, Ross Andrews, Jonathan Carapetis, Joseph McDonnell, Vicki Krause, Peter Stanley Morris

Journal article  |  2021  |  Vaccine X

BACKGROUND: Aboriginal children living in remote communities are at high risk of early and persistent otitis media. Streptococcus ..

Should prioritising health interventions be informed by modelling studies? The case of cancer control in Aotearoa New Zealand

Nick Wilson, Leah Grout, Jennifer Summers, Amanda C Jones, Anja Mizdrak, Nhung Nghiem, Cristina Cleghorn, Tony Blakely

Journal article  |  2021  |  NEW ZEALAND MEDICAL JOURNAL

In this viewpoint, we suggest that policymakers should prioritise health interventions by using evidence around health gain, impac..

Cellular Microenvironment Stiffness Regulates Eicosanoid Production and Signaling Pathways

Asres Berhan, Trudi Harris, Jade Jaffar, Fernando Jativa, Shenna Langenbach, Ingrid Loennstedt, Monther Alhamdoosh, Milica Ng, Peter Lee, Glen Westall, Nick Wilson, Michael Wilson, Alastair G Stewart

Journal article  |  2020  |  AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pathological changes in the biomechanical environment are implicated in the progression of idiopathic pulmonary fibrosis (IPF). St..

Novel Therapies for Pneumonia-Associated Severe Asthma Phenotypes

Angelica Papanicolaou, Hao Wang, Catherine Satzke, Ross Vlahos, Nick Wilson, Steven Bozinovski

Journal article  |  2020  |  TRENDS IN MOLECULAR MEDICINE

Distinct asthma phenotypes are emerging from well-defined cohort studies and appear to be associated with a history of pneumonia. ..

G-CSFR antagonism reduces neutrophilic inflammation during pneumococcal and influenza respiratory infections without compromising clearance

Hao Wang, Christian Aloe, Nick Wilson, Steven Bozinovski

Journal article  |  2019  |  SCIENTIFIC REPORTS

Excessive neutrophilic inflammation can contribute to the pathogenesis of pneumonia. Whilst anti-inflammatory therapies such as co..