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Human gamma delta T-cell receptor repertoire is shaped by influenza viruses, age and tissu..
IFN gamma-Induced MHC Class II Expression on Islet Endothelial Cells Is an Early Marker of..
Displaying the 24 most recent scholarly works by Stuart Mannering.
Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes
Kriti Joshi, Colleen Elso, Ali Motazedian, Tanya Labonne, Jacqueline V Schiesser, Fergus Cameron, Stuart I Mannering, Andrew G Elefanty, Edouard G Stanley
Journal article | 2019 | Diabetologia
AIMS/HYPOTHESIS: Type 1 diabetes is an autoimmune disorder characterised by loss of insulin-producing beta cells of the pancreas. ..
Divergent SATB1 expression across human life span and tissue compartments
Simone Nussing, Hui-Fern Koay, Sneha Sant, Thomas Loudovaris, Stuart I Mannering, Martha Lappas, Yves d'Udekem, Igor E Konstantinov, Stuart P Berzins, Guus F Rimmelzwaan, Stephen J Turner, E Bridie Clemens, Dale I Godfrey, HO Nguyen Thi, Katherine Kedzierska
Journal article | 2019 | Immunology & Cell Biology
Human CD8( ) T cell cross-reactivity across influenza A, B and C viruses
Marios Koutsakos, Patricia T Illing, Thi HO Nguyen, Nicole A Mifsud, Jeremy Chase Crawford, Simone Rizzetto, Auda A Eltahla, E Bridie Clemens, Sneha Sant, Brendon Y Chua, Chinn Yi Wong, E Kaitlynn Allen, Don Teng, Pradyot Dash, David F Boyd, Ludivine Grzelak, Weiguang Zeng, Aeron C Hurt, Ian Barr, Steve Rockman, et al.
Journal article | 2019 | Nature Immunology
Human gamma delta T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation
Sneha Sant, Misty R Jenkins, Pradyot Dash, Katherine A Watson, Zhongfang Wang, Angela Pizzolla, Marios Koutsakos, Thi HO Nguyen, Martha Lappas, Jane Crowe, Tom Loudovaris, Stuart Mannering, Glen P Westall, Tom C Kotsimbos, Allen C Cheng, Linda Wakim, Peter C Doherty, Paul G Thomas, Liyen Loh, Katherine Kedzierska
Journal article | 2019 | Clinical & Translational Immunology
IFN gamma-Induced MHC Class II Expression on Islet Endothelial Cells Is an Early Marker of Insulitis but Is Not Required for Diabetogenic CD4( ) T Cell Migration
Nicholas A Scott, Yuxing Zhao, Balasubramanian Krishnamurthy, Stuart I Mannering, Thomas WH Kay, Helen E Thomas
Journal article | 2018 | Frontiers in Immunology
Proinsulin C-peptide is an autoantigen in people with type 1 diabetes
Michelle So, Colleen M Elso, Eleonora Tresoldi, Miha Pakusch, Vimukthi Pathiraja, John M Wentworth, Leonard C Harrison, Balasubramanian Krishnamurthy, Helen E Thomas, Christine Rodda, Fergus J Cameron, Jacinta McMahon, Thomas WH Kay, Stuart I Mannering
Journal article | 2018 | Proceedings of the National Academy of Sciences
Single-Cell Approach to Influenza Specific CD8( ) T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection
Sneha Sant, Ludiyine Grzelak, Zhongfang Wang, Angela Pizzollal, Manbs Koutsakos, Jane Crowe, Thomas Loudoyaris, Stuart I Mannering, Glen P Westall, Linda M Wakiml, Jamie Rossjohn, Stephanie Gras, Michael Richards, Jianqing Xu, Paul G Thomas, Liyen Loh, Thi H Nguyen, Katherine Kedzierska
Journal article | 2018 | Frontiers in Immunology
Circulating T-FH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity
Marios Koutsakos, Adam K Wheatley, Liyen Loh, E Bridie Clemens, Sneha Sant, Simone Nussing, Annette Fox, Amy W Chung, Karen L Laurie, Aeron C Hurt, Steve Rockman, Martha Lappas, Thomas Loudovaris, Stuart I Mannering, Glen P Westall, Michael Elliot, Stuart G Tangye, Linda M Wakim, Stephen J Kent, Thi HO Nguyen, et al.
Journal article | 2018 | Science Translational Medicine
Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles
Angela Pizzolla, Thi HO Nguyen, Sneha Sant, Jade Jaffar, Tom Loudovaris, Stuart I Mannering, Paul G Thomas, Glen P Westall, Katherine Kedzierska, Linda M Wakim
Journal article | 2018 | Journal of Clinical Investigation
Deciphering the Pathogenesis of Human Type 1 Diabetes (T1D) by Interrogating T Cells from the "Scene of the Crime".
Sally C Kent, Stuart I Mannering, Aaron W Michels, Jenny Aurielle B Babon
Journal article | 2017 | Current Diabetes Reports
PURPOSE OF REVIEW: Autoimmune-mediated destruction of insulin-producing β-cells within the pancreas results in type 1 diabetes (T1..
Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice
Prerak M Trivedi, Kate L Graham, Nicholas A Scott, Misty R Jenkins, Suktilang Majaw, Robyn M Sutherland, Stacey Fynch, Andrew M Lew, Christopher J Burns, Balasubramanian Krishnamurthy, Thomas C Brodnicki, Stuart I Mannering, Thomas W Kay, Helen E Thomas
Journal article | 2017 | Diabetes
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion.
Thomas Delong, Timothy A Wiles, Rocky L Baker, Brenda Bradley, Gene Barbour, Richard Reisdorph, Michael Armstrong, Roger L Powell, Nichole Reisdorph, Nitesh Kumar, Colleen M Elso, Megan DeNicola, Rita Bottino, Alvin C Powers, David M Harlan, Sally C Kent, Stuart I Mannering, Kathryn Haskins
Journal article | 2016 | Science
T cell-mediated destruction of insulin-producing β cells in the pancreas causes type 1 diabetes (T1D). CD4 T cell responses play a..
Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time
Misty R Jenkins, Jesse A Rudd-Schmidt, Jamie A Lopez, Kelly M Ramsbottom, Stuart I Mannering, Daniel M Andrews, Ilia Voskoboinik, Joseph A Trapani
Journal article | 2015 | The Journal of Experimental Medicine
Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer-Restricted CD4( ) T Cells Infiltrate Islets in Type 1 Diabetes
Vimukthi Pathiraja, Janine P Kuehlich, Peter D Campbell, Balasubramanian Krishnamurthy, Thomas Loudovaris, P Toby H Coates, Thomas C Brodnicki, Philip J O'Connell, Katherine Kedzierska, Christine Rodda, Philip Bergman, Erin Hill, Anthony W Purcell, Nadine L Dudek, Helen E Thomas, Thomas WH Kay, Stuart I Mannering
Journal article | 2015 | Diabetes
Biased T Cell Receptor Usage Directed against Human Leukocyte Antigen DQ8-Restricted Gliadin Peptides Is Associated with Celiac Disease
Sophie E Broughton, Jan Petersen, Alex Theodossis, Stephen W Scally, Khai Lee Loh, Allan Thompson, Jeroen van Bergen, Yvonne Kooy-Winkelaar, Kate N Henderson, Travis Beddoe, Jason A Tye-Din, Stuart I Mannering, Anthony W Purcell, James McCluskey, Robert P Anderson, Frits Koning, Hugh H Reid, Jamie Rossjohn
Journal article | 2012 | Immunity
Residual methylprednisolone suppresses human T-cell responses to spleen, but not islet, extracts from deceased organ donors
Max Joffe, Andra S Necula, Rochna Chand, Brett C McWhinney, Balasubramanian Krishnamurthy, Tom Loudovaris, David Goodman, Helen E Thomas, Thomas WH Kay, Stuart I Mannering
Journal article | 2012 | International Immunology
Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease.
Kate L Graham, Robyn M Sutherland, Stuart I Mannering, Yuxing Zhao, Jonathan Chee, Balasubramanian Krishnamurthy, Helen E Thomas, Andrew M Lew, Thomas WH Kay
Journal article | 2012 | The Review of Diabetic Studies
Recent advances in our understanding of the pathogenesis of type 1 diabetes have occurred in all steps of the disease. This review..
Medicine - St Vincent'S Hospital
Doctor of Philosophy (Immunology)
University of Otago