Michael Goddard

Application of multivariate single-step SNP best linear unbiased predictor model and revised SNP list for genomic evaluation of dairy cattle in Australia

KV Konstantinov, ME Goddard

Journal article  |  2020  |  Journal of Dairy Science

The objectives of this study were (1) to evaluate the computational feasibility of the multitrait test-day single-step SNP-BLUP (s..

Meta-analysis for milk fat and protein percentage using imputed sequence variant genotypes in 94,321 cattle from eight cattle breeds

Irene van den Berg, Ruidong Xiang, Janez Jenko, Hubert Pausch, Mekki Boussaha, Chris Schrooten, Thierry Tribout, Arne B Gjuvsland, Didier Boichard, Oyvind Nordbo, Marie-Pierre Sanchez, Mike E Goddard

Journal article  |  2020  |  Genetics Selection Evolution

Effect direction meta-analysis of GWAS identifies extreme, prevalent and shared pleiotropy in a large mammal

Ruidong Xiang, Irene van den Berg, Iona M MacLeod, Hans D Daetwyler, Michael E Goddard

Journal article  |  2020  |  Communications Biology

In genome-wide association studies (GWAS), variants showing consistent effect directions across populations are considered as true..

Improved polygenic prediction by Bayesian multiple regression on summary statistics

Luke R Lloyd-Jones, Jian Zeng, Julia Sidorenko, Loic Yengo, Gerhard Moser, Kathryn E Kemper, Huanwei Wang, Zhili Zheng, Reedik Magi, Tonu Esko, Andres Metspalu, Naomi R Wray, Michael E Goddard, Jian Yang, Peter M Visscher

Journal article  |  2019  |  Nature Communications

Accurate prediction of an individual's phenotype from their DNA sequence is one of the great promises of genomics and precision me..

Strong selection pressures maintain divergence on genomic islands in Atlantic cod (Gadus morhua L.) populations

Silvia T Rodriguez-Ramilo, Matthew Baranski, Hooman Moghadam, Harald Grove, Sigbjorn Lien, Mike E Goddard, Theo HE Meuwissen, Anna K Sonesson

Journal article  |  2019  |  Genetics Selection Evolution

BACKGROUND: Two distinct populations have been extensively studied in Atlantic cod (Gadus morhua L.): the Northeast Arctic cod (NE..

Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits

Ruidong Xiang, Irene van den Berg, Iona M MacLeod, Benjamin J Hayes, Claire P Prowse-Wilkins, Min Wang, Sunduimijid Bolormaa, Zhiqian Liu, Simone J Rochfort, Coralie M Reich, Brett A Mason, Christy J Vander Jagt, Hans D Daetwyler, Mogens S Lund, Amanda J Chamberlain, Michael E Goddard

Journal article  |  2019  |  Proceedings of the National Academy of Sciences

The use of mid-infrared spectra to map genes affecting milk composition

A Benedet, PN Ho, R Xiang, S Bolormaa, M De Marchi, ME Goddard, JE Pryce

Journal article  |  2019  |  Journal of Dairy Science

Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

Huanwei Wang, Futao Zhang, Jian Zeng, Yang Wu, Kathryn E Kemper, Angli Xue, Min Zhang, Joseph E Powell, Michael E Goddard, Naomi R Wray, Peter M Visscher, Allan F McRae, Jian Yang

Journal article  |  2019  |  Science Advances

Overlap between eQTL and QTL associated with production traits and fertility in dairy cattle

I van den Berg, BJ Hayes, AJ Chamberlain, ME Goddard

Journal article  |  2019  |  BMC Genomics

Complex Trait Prediction from Genome Data: Contrasting EBV in Livestock to PRS in Humans Genomic Prediction

Naomi R Wray, Kathryn E Kemper, Benjamin J Hayes, Michael E Goddard, Peter M Visscher

Journal article  |  2019  |  Genetics