Michael Goddard

Quantifying genetic heterogeneity between continental populations for human height and body mass index.

Jing Guo, Andrew Bakshi, Ying Wang, Longda Jiang, Loic Yengo, Michael E Goddard, Peter M Visscher, Jian Yang

Journal article  |  2021  |  Scientific Reports

Genome-wide association studies (GWAS) in samples of European ancestry have identified thousands of genetic variants associated wi..

On the use of whole-genome sequence data for across-breed genomic prediction and fine-scale mapping of QTL

Theo Meuwissen, Irene van den Berg, Mike Goddard

Journal article  |  2021  |  Genetics Selection Evolution

BACKGROUND: Whole-genome sequence (WGS) data are increasingly available on large numbers of individuals in animal and plant breedi..

Genetic parameters for methane emission traits in Australian dairy cows

CM Richardson, TTT Nguyen, M Abdelsayed, PJ Moate, SRO Williams, TCS Chud, FS Schenkel, ME Goddard, I van den Berg, BG Cocks, LC Marett, WJ Wales, JE Pryce

Journal article  |  2021  |  Journal of Dairy Science

Methane is a greenhouse gas of high interest to the dairy industry, with 57% of Australia's dairy emissions attributed to enteric ..

Improving Genomic Prediction of Crossbred and Purebred Dairy Cattle

Majid Khansefid, Michael E Goddard, Mekonnen Haile-Mariam, Kon Konstantinov, Chris Schrooten, Gerben de Jong, Erica G Jewell, Erin O'Connor, Jennie E Pryce, Hans D Daetwyler, Iona M MacLeod

Journal article  |  2020  |  Frontiers in Genetics

This study assessed the accuracy and bias of genomic prediction (GP) in purebred Holstein (H) and Jersey (J) as well as crossbred ..

Application of multivariate single-step SNP best linear unbiased predictor model and revised SNP list for genomic evaluation of dairy cattle in Australia

KV Konstantinov, ME Goddard

Journal article  |  2020  |  Journal of Dairy Science

The objectives of this study were (1) to evaluate the computational feasibility of the multitrait test-day single-step SNP-BLUP (s..

Meta-analysis for milk fat and protein percentage using imputed sequence variant genotypes in 94,321 cattle from eight cattle breeds

Irene van den Berg, Ruidong Xiang, Janez Jenko, Hubert Pausch, Mekki Boussaha, Chris Schrooten, Thierry Tribout, Arne B Gjuvsland, Didier Boichard, Oyvind Nordbo, Marie-Pierre Sanchez, Mike E Goddard

Journal article  |  2020  |  Genetics Selection Evolution

Effect direction meta-analysis of GWAS identifies extreme, prevalent and shared pleiotropy in a large mammal

Ruidong Xiang, Irene van den Berg, Iona M MacLeod, Hans D Daetwyler, Michael E Goddard

Journal article  |  2020  |  Communications Biology

In genome-wide association studies (GWAS), variants showing consistent effect directions across populations are considered as true..

Improved polygenic prediction by Bayesian multiple regression on summary statistics

Luke R Lloyd-Jones, Jian Zeng, Julia Sidorenko, Loic Yengo, Gerhard Moser, Kathryn E Kemper, Huanwei Wang, Zhili Zheng, Reedik Magi, Tonu Esko, Andres Metspalu, Naomi R Wray, Michael E Goddard, Jian Yang, Peter M Visscher

Journal article  |  2019  |  Nature Communications

Accurate prediction of an individual's phenotype from their DNA sequence is one of the great promises of genomics and precision me..

Strong selection pressures maintain divergence on genomic islands in Atlantic cod (Gadus morhua L.) populations

Silvia T Rodriguez-Ramilo, Matthew Baranski, Hooman Moghadam, Harald Grove, Sigbjorn Lien, Mike E Goddard, Theo HE Meuwissen, Anna K Sonesson

Journal article  |  2019  |  Genetics Selection Evolution

BACKGROUND: Two distinct populations have been extensively studied in Atlantic cod (Gadus morhua L.): the Northeast Arctic cod (NE..

Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits

Ruidong Xiang, Irene van den Berg, Iona M MacLeod, Benjamin J Hayes, Claire P Prowse-Wilkins, Min Wang, Sunduimijid Bolormaa, Zhiqian Liu, Simone J Rochfort, Coralie M Reich, Brett A Mason, Christy J Vander Jagt, Hans D Daetwyler, Mogens S Lund, Amanda J Chamberlain, Michael E Goddard

Journal article  |  2019  |  Proceedings of the National Academy of Sciences of USA