Lesley Bretherton

Agreement between parents? and clinical researchers? ratings of behavioral problems in children with fragile X syndrome and chromosome 15 imprinting disorders

Marta Arpone, Lesley Bretherton, David J Amor, Stephen JC Hearps, Carolyn Rogers, Michael J Field, Matthew F Hunter, Lorena Santa Maria, Angelica M Alliende, Jennie Slee, David E Godler, Emma K Baker

Journal article  |  2022  |  RESEARCH IN DEVELOPMENTAL DISABILITIES

BACKGROUND: Despite the increasing number of clinical trials involving children with neurodevelopmental disorders, appropriate and..

Prediction of clinical anxious and depressive problems in mid childhood amongst temperamentally inhibited preschool children: a population study

Jordana K Bayer, Luke A Prendergast, Amy Brown, Lesley Bretherton, Harriet Hiscock, Margaret Nelson-Lowe, Tamsyn Gilbertson, Kate Noone, Natalie Bischof, Cassima Beechey, Fenny Muliadi, Cathrine Mihalopoulos, Ronald M Rapee

Journal article  |  2021  |  EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Shy/inhibited young children are at risk for internalising difficulties; however, for many, this temperamental style does not resu..

Follow-up of the Cool Little Kids translational trial into middle childhood

Jordana K Bayer, Amy Brown, Luke A Prendergast, Lesley Bretherton, Harriet Hiscock, Cathrine Mihalopoulos, Margaret Nelson-Lowe, Tamsyn Gilbertson, Kate Noone, Natalie Bischof, Cassima Beechey, Fenny Muliadi, Ronald M Rapee

Journal article  |  2021  |  JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

BACKGROUND: Public health advocates have highlighted internalising problems as a leading cause of global burden of disease. Intern..

Infant Regulation: Associations with Child Language Development in a Longitudinal Cohort

Fallon Cook, Laura Conway, Emina Omerovic, Petrea Cahir, Rebecca Giallo, Harriet Hiscock, Fiona Mensah, Lesley Bretherton, Edith Bavin, Patricia Eadie, Stephanie Brown, Sheena Reilly

Journal article  |  2021  |  JOURNAL OF PEDIATRICS

OBJECTIVE: To determine whether infants who have regulatory problems (eg, sleeping, crying, and feeding problems) at 1 year of age..

Predictors in Infancy for Language and Academic Outcomes at 11 Years

Patricia Eadie, Edith L Bavin, Lesley Bretherton, Fallon Cook, Lisa Gold, Fiona Mensah, Melissa Wake, Sheena Reilly

Journal article  |  2021  |  PEDIATRICS

OBJECTIVES: To examine the contribution of early life factors and preschool- and school-aged language abilities to children's 11-y..

DNA Methylation at Birth Predicts Intellectual Functioning and Autism Features in Children with Fragile X Syndrome

Claudine M Kraan, Emma K Baker, Marta Arpone, Minh Bui, Ling Ling, Dinusha Gamage, Lesley Bretherton, Carolyn Rogers, Michael J Field, Tiffany L Wotton, David Francis, Matt F Hunter, Jonathan Cohen, David J Amor, David E Godler

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fragile X syndrome (FXS) is a leading single-gene cause of intellectual disability (ID) with autism features. This study analysed ..

Cool Little Kids translational trial to prevent internalising: two-year outcomes and prediction of parent engagement

Jordana K Bayer, Luke A Prendergast, Amy Brown, Lana Harris, Lesley Bretherton, Harriet Hiscock, Ruth Beatson, Cathrine Mihalopoulos, Ronald M Rapee

Journal article  |  2020  |  CHILD AND ADOLESCENT MENTAL HEALTH

BACKGROUND: The aim was to determine outcomes in the first year of school of a population-delivered parenting program to prevent i..

FMR1 mRNA from full mutation alleles is associated with ABC-C-FX scores in males with fragile X syndrome

Emma K Baker, Marta Arpone, Claudine Kraan, Bui Minh, Carolyn Rogers, Michael Field, Lesley Bretherton, Ling Ling, Alexandra Ure, Jonathan Cohen, Matthew F Hunter, Lorena Santa Maria, Victor Faundes, Bianca Curotto, Paulina Morales, Cesar Trigo, Isabel Salas, Angelica Alliende, David J Amor, David E Godler

Journal article  |  2020  |  SCIENTIFIC REPORTS

Fragile X syndrome (FXS) is caused by a hypermethylated full mutation (FM) expansion with ≥ 200 CGG repeats, and a decrease in FMR..

Cost-effectiveness of preventing child internalising problems: Results from the translational trial of Cool Little Kids at school entry

Mary Lou Chatterton, Jordana K Bayer, Lidia Engel, Ronald M Rapee, Ruth Beatson, Harriet Hiscock, Lesley Bretherton, Melissa Wake, Cathrine Mihalopoulos

Journal article  |  2020  |  JOURNAL OF ANXIETY DISORDERS

OBJECTIVE: A translational trial evaluated the effectiveness of screening for inhibited childhood temperament, followed by a preve..

Intellectual functioning and behavioural features associated with mosaicism in fragile X syndrome

Emma K Baker, Marta Arpone, Solange Aliaga Vera, Lesley Bretherton, Alexandra Ure, Claudine M Kraan, Minh Bui, Ling Ling, David Francis, Matthew F Hunter, Justine Elliott, Carolyn Rogers, Michael J Field, Jonathan Cohen, Lorena Santa Maria, Victor Faundes, Bianca Curotto, Paulina Morales, Cesar Trigo, Isabel Salas, et al.

Journal article  |  2019  |  JOURNAL OF NEURODEVELOPMENTAL DISORDERS

BACKGROUND: Fragile X syndrome (FXS) is a common cause of intellectual disability and autism spectrum disorder (ASD) usually assoc..