Xiaowei Wang

Smart Delivery of Plasminogen Activators for Efficient Thrombolysis; Recent Trends and Future Perspectives

Ahmed Refaat, Blanca del Rosal, Jathushan Palasubramaniam, Geoffrey Pietersz, Xiaowei Wang, Karlheinz Peter, Simon E Moulton

Journal article  |  2021  |  ADVANCED THERAPEUTICS

Fibrinolytic drugs have been successfully used to manage acute thrombotic and thromboembolic conditions. However, their narrow adm..

Visions by Women in Molecular Imaging Network: Antiracism and Allyship in Action

Eman Akam, Carmen Azevedo, Aisling M Chaney, Savita Dhanvantari, Kimberly J Edwards, Kelly E Henry, Oluwatosin Y Ibhagui, Jenny N Ijoma, Oluwatayo F Ikotun, Kyeara N Mack, Veronica L Nagle, Patricia MR Pereira, Mona L Purcell, Vanessa A Sanders, Monica Shokeen, Xiaowei Wang

Journal article  |  2021  |  MOLECULAR IMAGING AND BIOLOGY

Recent events in America in 2020 have stimulated a worldwide movement to dismantle anti-Black racism in all facets of our lives. A..

A DARPin targeting activated Mac-1 is a novel diagnostic tool and potential anti-inflammatory agent in myocarditis, sepsis and myocardial infarction

Patrick M Siegel, Istvan Bojti, Nicole Bassler, Jessica Holien, Ulrike Flierl, Xiaowei Wang, Philipp Waggershauser, Xavier Tonnar, Christopher Vedecnik, Constanze Lamprecht, Ivana Stankova, Tian Li, Thomas Helbing, Dennis Wolf, Nathaly Anto-Michel, Lucia Sol Mitre, Julia Ehrlich, Lukas Orlean, Ileana Bender, Anne Przewosnik, et al.

Journal article  |  2021  |  BASIC RESEARCH IN CARDIOLOGY

The monocyte β2-integrin Mac-1 is crucial for leukocyte-endothelium interaction, rendering it an attractive therapeutic target for..

Platelets in Multiple Sclerosis: Early and Central Mediators of Inflammation and Neurodegeneration and Attractive Targets for Molecular Imaging and Site-Directed Therapy

Jacqueline M Orian, Claretta S D'Souza, Pece Kocovski, Guy Krippner, Matthew W Hale, Xiaowei Wang, Karlheinz Peter

Journal article  |  2021  |  FRONTIERS IN IMMUNOLOGY

Platelets are clearly central to thrombosis and hemostasis. In addition, more recently, evidence has emerged for non-hemostatic ro..

Considerations for the Bioengineering of Advanced Cardiac In Vitro Models of Myocardial Infarction

Poonam Sharma, Xiaowei Wang, Clara Liu Chung Ming, Laura Vettori, Gemma Figtree, Andrew Boyle, Carmine Gentile

Journal article  |  2021  |  SMALL

Despite the latest advances in cardiovascular biology and medicine, myocardial infarction (MI) remains one of the major causes of ..

Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities

Laura A Bienvenu, Jonathan Noonan, Xiaowei Wang, Karlheinz Peter

Journal article  |  2020  |  CARDIOVASCULAR RESEARCH

The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is a critical concern of the cor..

The choice of targets and ligands for site-specific delivery of nanomedicine to atherosclerosis

Adil Zia, Yuao Wu, Nguyen Tuan, Xiaowei Wang, Karlheinz Peter, Hang T Ta

Journal article  |  2020  |  CARDIOVASCULAR RESEARCH

As nanotechnologies advance into clinical medicine, novel methods for applying nanomedicine to cardiovascular diseases are emergin..

Combined Antiplatelet/Anticoagulant Drug for Cardiac Ischemia/Reperfusion Injury

Laura A Bienvenu, Ana Maluenda, James D McFadyen, Amy K Searle, Eefang Yu, Carolyn Haller, Elliot L Chaikof, Karlheinz Peter, Xiaowei Wang

Journal article  |  2020  |  CIRCULATION RESEARCH

Antithrombotic Therapy in Myocardial Infarction: Historic Perils and Current Challenges-A 70-Year Journey

Himawan Fernando, James D McFadyen, Jathushan Palasubramaniam, James Shaw, Xiaowei Wang, Dion Stub, Karlheinz Peter

Journal article  |  2020  |  THROMBOSIS AND HAEMOSTASIS

There have been numerous and intriguing advancements in antithrombotic therapy for myocardial infarction since it was described in..

Fluorine-19 Magnetic Resonance Imaging of Activated Platelets

Xiaowei Wang, Sebastian Temme, Christoph Grapentin, Jathushan Palasubramaniam, Aidan Walsh, Wolfgang Kraemer, Patricia Kleimann, Asli Havlas, Rolf Schubert, Juergen Schrader, Ulrich Floegel, Karlheinz Peter

Journal article  |  2020  |  JOURNAL OF THE AMERICAN HEART ASSOCIATION