Bill Kalionis

The Placental NLRP3 Inflammasome and Its Downstream Targets, Caspase-1 and Interleukin-6, Are Increased in Human Fetal Growth Restriction: Implications for Aberrant Inflammation-Induced Trophoblast Dysfunction

Irvan Alfian, Amlan Chakraborty, Hannah EJ Yong, Sheetal Saini, Ricky WK Lau, Bill Kalionis, Evdokia Dimitriadis, Nadia Alfaidy, Sharon D Ricardo, Chrishan S Samuel, Padma Murthi

Journal article  |  2022  |  CELLS

Fetal growth restriction (FGR) is commonly associated with placental insufficiency and inflammation. Nonetheless, the role played ..

Mesenchymal Stem/Stromal Cells and Their Role in Oxidative Stress Associated with Preeclampsia

Gina D Kusuma, Harry M Georgiou, Anthony Perkins, Mohamed H Abumaree, Shaun P Brennecke, Bill Kalionis

Journal article  |  2022  |  YALE JOURNAL OF BIOLOGY AND MEDICINE

Preeclampsia (PE) is a serious medically important disorder of human pregnancy, which features de novo pregnancy-induced hypertens..

Improvement of Mesenchymal Stromal Cell Proliferation and Differentiation via Decellularized Extracellular Matrix on Substrates With a Range of Surface Chemistries.

Michael C Yang, Andrea J O'Connor, Bill Kalionis, Daniel E Heath

Journal article  |  2022  |  Front Med Technol

Decellularized extracellular matrix (dECM) deposited by mesenchymal stromal cells (MSCs) has emerged as a promising substrate for ..

Late/post-term decidual basalis-derived mesenchymal stem/stromal cells show evidence of advanced ageing and downregulation of microRNA-516b-5p

Ramin Khanabdali, Shixuan Zheng, Phillip E Melton, Harry M Georgiou, Eric Moses, Shaun P Brennecke, Bill Kalionis

Journal article  |  2021  |  PLACENTA

INTRODUCTION: The placenta is a short-lived organ, yet it shows signs of progressive ageing in the third trimester. Studies of age..

The Emerging Role of the Prokineticins and Homeobox Genes in the Vascularization of the Placenta: Physiological and Pathological Aspects

Nadia Alfaidy, Sophie Brouillet, Gayathri Rajaraman, Bill Kalionis, Pascale Hoffmann, Tiphaine Barjat, Mohamed Benharouga, Padma Murthi

Journal article  |  2020  |  FRONTIERS IN PHYSIOLOGY

Vasculogenesis and angiogenesis are key processes of placental development, which occur throughout pregnancy. Placental vasculogen..

Ageing in human parturition: impetus of the gestation clock in the decidua

Joan C Wijaya, Ramin Khanabdali, Harry M Georgiou, Bill Kalionis

Journal article  |  2020  |  BIOLOGY OF REPRODUCTION

Despite sharing many common features, the relationship between ageing and parturition remains poorly understood. The decidua is a ..

Decidual mesenchymal stem/stromal cell-derived extracellular vesicles ameliorate endothelial cell proliferation, inflammation, and oxidative stress in a cell culture model of preeclampsia

Shixuan Zheng, Aiwu Shi, Sophia Hill, Claire Grant, Maria I Kokkinos, Padma Murthi, Harry M Georgiou, Shaun P Brennecke, Bill Kalionis

Journal article  |  2020  |  Pregnancy Hypertension

Oxidative stress and endothelial dysfunction contribute substantially to the pathogenesis of preeclampsia (PE). Decidual mesenchym..

Functional changes in decidual mesenchymal stem/stromal cells are associated with spontaneous onset of labour

Joan C Wijaya, Ramin Khanabdali, Harry M Georgiou, Maria Kokkinos, Patrick F James, Shaun P Brennecke, Bill Kalionis

Journal article  |  2020  |  Molecular Human Reproduction

Ageing and parturition share common pathways, but their relationship remains poorly understood. Decidual cells undergo ageing as p..

Innate immune responses to malaria-infected erythrocytes in pregnant women: Effects of gravidity, malaria infection, and geographic location

Marzieh Jabbarzare, Madi Njie, Anthony Jaworowski, Alexandra J Umbers, Maria Ome-Kaius, Wina Hasang, Louise M Randall, Bill Kalionis, Stephen J Rogerson

Journal article  |  2020  |  PLOS ONE

BACKGROUND: Malaria in pregnancy causes maternal, fetal and neonatal morbidity and mortality, and maternal innate immune responses..

Preconditioning of Human Decidua Basalis Mesenchymal Stem/Stromal Cells with Glucose Increased Their Engraftment and Anti-diabetic Properties (vol 17, pg 209, 2020)

Yasser Basmaeil, Manar Al Rashid, Tanvir Khatlani, Manal AlShabibi, Eman Bahattab, Meshan L Abdullah, Fawaz Abomaray, Bill Kalionis, Safia Massoudi, Mohamed Abumaree

Journal article  |  2020  |  TISSUE ENGINEERING AND REGENERATIVE MEDICINE

The author would like to correct the names for the below co-authors in the online published article.