Christian Gunawan

Synthetic beta-1,2-Mannosyloxymannitol Glycolipid from the Fungus Malassezia pachydermatis Signals through Human Mincle

Phillip L van der Peet, Christian Gunawan, Miyuki Watanabe, Sho Yamasaki, Spencer J Williams

Journal article  |  2019  |  JOURNAL OF ORGANIC CHEMISTRY

Mincle is a C-type lectin receptor of the innate immune system with the ability to sense pathogens and commensals through lipidic ..

Gram scale preparation of clozapine N-oxide (CNO), a synthetic small molecule actuator for muscarinic acetylcholine DREADDs

Phillip L van der Peet, Christian Gunawan, Alaa Abdul-Ridha, Sherie Ma, Daniel J Scott, Andrew L Gundlach, Ross AD Bathgate, Jonathan M White, Spencer J Williams

Journal article  |  2018  |  METHODSX

Chemogenetics uses engineered proteins that are controlled by small molecule actuators, allowing in vivo functional studies of pro..

Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle

Phillip L van der Peet, Christian Gunawan, Shota Torigoe, Sho Yamasaki, Spencer J Williams

Journal article  |  2015  |  CHEMICAL COMMUNICATIONS

An enantioselective synthesis of (+)-corynomycolic acid, and its elaboration to esters of trehalose, glucose and glycerol, is desc..

A Click Chemistry Approach to 5,5 '-Disubstituted-3,3 '-Bisisoxazoles from Dichloroglyoxime and Alkynes: Luminescent Organometallic Iridium and Rhenium Bisisoxazole Complexes

Phillip L van der Peet, Timothy U Connell, Christian Gunawan, Jonathan M White, Paul S Donnelly, Spencer J Williams

Journal article  |  2013  |  JOURNAL OF ORGANIC CHEMISTRY

5,5'-Disubstituted-3,3'-bisisoxazoles are prepared in one step by the dropwise addition of aqueous potassium hydrogen carbonate to..

Formal Total Synthesis of Spirangien A

Claire Gregg, Christian Gunawan, Audrey Wei Yi Ng, Samantha Wimala, Sonali Wickremasinghe, Mark A Rizzacasa

Journal article  |  2013  |  ORGANIC LETTERS

A formal total synthesis of the spiroketal containing cytotoxic myxobacteria metabolite spirangien A (1) is described. The approac..