Alex Andrianopoulos

The novel Dbl homology/BAR domain protein, MsgA, of Talaromyces marneffei regulates yeast morphogenesis during growth inside host cells

Harshini Weerasinghe, Hayley E Bugeja, Alex Andrianopoulos

Journal article  |  2021  |  SCIENTIFIC REPORTS

Microbial pathogens have evolved many strategies to evade recognition by the host immune system, including the use of phagocytic c..

Antifungal Activity and Molecular Mechanisms of Partial Purified Antifungal Proteins from Rhinacanthus nasutus against Talaromyces marneffei

Juthatip Jeenkeawpieam, Supachai Yodkeeree, Alex Andrianopoulos, Sittiruk Roytrakul, Monsicha Pongpom

Journal article  |  2020  |  JOURNAL OF FUNGI

Antifungal proteins (AFPs) are able to inhibit a wide spectrum of fungi without significant toxicity to the hosts. This study exam..

Adaptation to Industrial Stressors Through Genomic and Transcriptional Plasticity in a Bioethanol Producing Fission Yeast Isolate

Dane Vassiliadis, Koon Ho Wong, Jo Blinco, Geoff Dumsday, Alex Andrianopoulos, Brendon Monahan

Journal article  |  2020  |  G3-GENES GENOMES GENETICS

Schizosaccharomyces pombe is a model unicellular eukaryote with ties to the basic research, oenology and industrial biotechnology ..

Calcineurin A Is Essential in the Regulation of Asexual Development, Stress Responses and Pathogenesis in Talaromyces marneffei

Yan-Qing Zheng, Kai-Su Pan, Jean-Paul Latge, Alex Andrianopoulos, Hong Luo, Ru-Fan Yan, Jin-Ying Wei, Chun-Yang Huang, Cun-Wei Cao

Journal article  |  2020  |  FRONTIERS IN MICROBIOLOGY

Talaromyces marneffei is a common cause of infection in immunocompromised patients in Southeast Asia and Southern China. The patho..

Laboratory Maintenance and Growth of Talaromyces marneffei.

Alex Andrianopoulos

Journal article  |  2020  |  Curr Protoc Microbiol

Talaromyces marneffei is an important opportunistic human pathogen endemic to Southeast Asia. It is one of a number of pathogenic ..

beta-glucan-dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment

Vahid Pazhakh, Felix Ellett, Ben A Croker, Joanne A O'Donnell, Luke Pase, Keith E Schulze, R Stefan Greulich, Aakash Gupta, Constantino Carlos Reyes-Aldasoro, Alex Andrianopoulos, Graham J Lieschke

Journal article  |  2019  |  PLOS BIOLOGY

The initial host response to fungal pathogen invasion is critical to infection establishment and outcome. However, the diversity o..

In Vitro Susceptibility of Berberine Combined with Antifungal Agents Against the Yeast Form of Talaromyces marneffei

Hong Luo, Kai-su Pan, Xiao-lu Luo, Dong-yan Zheng, Alex Andrianopoulos, Le-min Wen, Yan-qing Zheng, Jing Guo, Chun-yang Huang, Xiu-ying Li, Rong Hu, Yu-jiao Li, Tian-min Li, Justin Joseph, Cun-wei Cao, Gang Liang

Journal article  |  2019  |  MYCOPATHOLOGIA

Talaromyces (Penicillium) marneffei can cause fatal disseminated infection in immunocompromised hosts. However, therapeutic strate..

A genome-wide analysis of carbon catabolite repression in Schizosaccharomyces pombe

Dane Vassiliadis, Koon Ho Wong, Alex Andrianopoulos, Brendon J Monahan

Journal article  |  2019  |  BMC GENOMICS

BACKGROUND: Optimal glucose metabolism is central to the growth and development of cells. In microbial eukaryotes, carbon cataboli..

A unique aspartyl protease gene expansion in Talaromyces marneffei plays a role in growth inside host phagocytes

Michael Payne, Harshini Weerasinghe, Irma Tedja, Alex Andrianopoulos

Journal article  |  2019  |  VIRULENCE

Aspartyl proteases are a widely represented class of proteolytic enzymes found in eukaryotes and retroviruses. They have been asso..

Morphological and metabolic adaptation to environmental conditions by Talaromyces marneffei and its role in the host.

Alex Andrianopoulos, Harshini Weerasinghe, Michael Payne

Conference Proceedings  |  2018  |  MEDICAL MYCOLOGY