Aswin Ratheesh

Cognitive ability and metabolic physical health in first-episode psychosis.

Sarah Whitson, Brian O'Donoghue, Robert Hester, Lara Baldwin, Susy Harrigan, Shona Francey, Jessica Graham, Barnaby Nelson, Aswin Ratheesh, Mario Alvarez-Jimenez, Alex Fornito, Christos Pantelis, Hok Pan Yuen, Andrew Thompson, Melissa Kerr, Michael Berk, Stephen J Wood, Patrick McGorry, Kelly Allott

Journal article  |  2021  |  Schizophrenia Research Cognition

Cognitive impairments are a core feature of first-episode psychosis (FEP), arising before illness onset and antipsychotic exposure..

Pluripotential Risk and Clinical Staging: Theoretical Considerations and Preliminary Data From a Transdiagnostic Risk Identification Approach

Jessica A Hartmann, Patrick D McGorry, Louise Destree, G Paul Amminger, Andrew M Chanen, Christopher G Davey, Rachid Ghieh, Andrea Polari, Aswin Ratheesh, Hok Pan Yuen, Barnaby Nelson

Journal article  |  2021  |  Frontiers in Psychiatry

Most psychiatric disorders develop during adolescence and young adulthood and are preceded by a phase during which attenuated or e..

Does guideline-concordant care predict naturalistic outcomes in youth with early stage bipolar I disorder?

Priya Sunder, Ming-Fang Chia, Kate Filia, Craig Macneil, Melissa Hasty, Christopher Davey, Patrick McGorry, Michael Berk, Sue Cotton, Aswin Ratheesh

Journal article  |  2021  |  Journal of Affective Disorders

BACKGROUND: The impact of guideline concordance on naturalistic maintenance treatment outcomes in BD is not known. We sought to ev..

A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don't work well enough?

Seetal Dodd, Michael Bauer, Andre F Carvalho, Harris Eyre, Maurizio Fava, Siegfried Kasper, Sidney H Kennedy, Jon-Paul Khoo, Carlos Lopez Jaramillo, Gin S Malhi, Roger S McIntyre, Philip B Mitchell, Angela Marianne Paredes Castro, Aswin Ratheesh, Emanuel Severus, Trisha Suppes, Madhukar H Trivedi, Michael E Thase, Lakshmi N Yatham, Allan H Young, et al.

Journal article  |  2020  |  The World Journal of Biological Psychiatry

BACKGROUND: Major depressive disorder is a common, recurrent, disabling and costly disorder that is often severe and/or chronic, a..

A Novel Multimodal Digital Service (Moderated Online Social Therapy plus ) for Help-Seeking Young People Experiencing Mental III-Health: Pilot Evaluation Within a National Youth E-Mental Health Service

Mario Alvarez-Jimenez, Simon Rice, Simon D'Alfonso, Steven Leicester, Sarah Bendall, Ingrid Pryor, Penni Russon, Carla McEnery, Olga Santesteban-Echarri, Gustavo Da Costa, Tamsyn Gilbertson, Lee Valentine, Laia Solves, Aswin Ratheesh, Patrick D McGorry, John Gleeson

Journal article  |  2020  |  Journal of Medical Internet Research

BACKGROUND: Mental ill-health is the leading cause of disability worldwide. Moreover, 75% of mental health conditions emerge betwe..

Rates, types and associations of sexual risk behaviours and sexually transmitted infections in those with severe mental illness: a scoping review

Meg Stevens, Aswin Ratheesh, Amity Watson, Kate Filia, Brian O Donoghue, Sue M Cotton

Journal article  |  2020  |  Psychiatry Research

The aim of this scoping review was to: (i) determine rates and types of sexual risk behaviours and sexually-transmitted infections..

Youth Depression Alleviation with Anti-inflammatory Agents (YoDA-A): a randomised clinical trial of rosuvastatin and aspirin

Michael Berk, Mohammadreza Mohebbi, Olivia M Dean, Sue M Cotton, Andrew M Chanen, Seetal Dodd, Aswin Ratheesh, G Paul Amminger, Mark Phelan, Amber Weller, Andrew Mackinnon, Francesco Giorlando, Shelley Baird, Lisa Incerti, Rachel E Brodie, Natalie O Ferguson, Simon Rice, Miriam R Schafer, Edward Mullen, Sarah Hetrick, et al.

Journal article  |  2020  |  BMC MEDICINE

BACKGROUND: Inflammation contributes to the pathophysiology of major depressive disorder (MDD), and anti-inflammatory strategies m..

Psychosocial Intervention With or Without Antipsychotic Medication for First-Episode Psychosis: A Randomized Noninferiority Clinical Trial

Shona M Francey, Brian O’Donoghue, Barnaby Nelson, Jessica Graham, Lara Baldwin, Hok Pan Yuen, Melissa J Kerr, Aswin Ratheesh, Kelly Allott, Mario Alvarez-Jimenez, Alex Fornito, Susy Harrigan, Andrew D Thompson, Stephen Wood, Michael Berk, Patrick D McGorry

Journal article  |  2020  |  Schizophrenia Bulletin Open

Abstract This triple-blind (participants, clinicians, and researchers) randomized controlled noninferiority trial e..

Can antipsychotic dose reduction lead to better functional recovery in first-episode psychosis? A randomized controlled-trial of antipsychotic dose reduction. The reduce trial: Study protocol

Amber Weller, John Gleeson, Mario Alvarez-Jimenez, Patrick McGorry, Barnaby Nelson, Kelly Allott, Sarah Bendall, Cali Bartholomeusz, Peter Koval, Susy Harrigan, Brian O'Donoghue, Alex Fornito, Christos Pantelis, G Paul Amminger, Aswin Ratheesh, Andrea Polari, Stephen J Wood, Kristi van der El, Carli Ellinghaus, Jesse Gates, et al.

Journal article  |  2019  |  EARLY INTERVENTION IN PSYCHIATRY

Antipsychotic medication has been the mainstay of treatment for psychotic illnesses for over 60 years. This has been associated wi..

Improving functional outcomes in early-stage bipolar disorder: The protocol for the REsearch into COgnitive and behavioural VERsatility trial

Sue M Cotton, Michael Berk, Henry Jackson, Greg Murray, Kate Filia, Melissa Hasty, Andrew Chanen, Christopher Davey, Barnaby Nelson, Aswin Ratheesh, Craig MacNeil

Journal article  |  2019  |  Early Intervention in Psychiatry

AIM: Young people with bipolar disorder (BD) commonly experience reduced quality of life, persistent symptoms and impaired functio..