Peter Doherty

Recalling the Future: Immunological Memory Toward Unpredictable Influenza Viruses

Maria Auladell, Xiaoxiao Jia, Luca Hensen, Brandon Chua, Annette Fox, Thi HO Nguyen, Peter C Doherty, Katherine Kedzierska

Journal article  |  2019  |  Frontiers in Immunology

CD4( ) T help promotes influenza virus-specific CD8( ) T cell memory by limiting metabolic dysfunction

Jolie G Cullen, Hayley A McQuilten, Kylie M Quinn, Moshe Olshansky, Brendan E Russ, Alison Morey, Sanna Wei, Julia E Prier, Nicole L La Gruta, Peter C Doherty, Stephen J Turner

Journal article  |  2019  |  Proceedings of the National Academy of Sciences

Human gamma delta T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation

Sneha Sant, Misty R Jenkins, Pradyot Dash, Katherine A Watson, Zhongfang Wang, Angela Pizzolla, Marios Koutsakos, Thi HO Nguyen, Martha Lappas, Jane Crowe, Tom Loudovaris, Stuart Mannering, Glen P Westall, Tom C Kotsimbos, Allen C Cheng, Linda Wakim, Peter C Doherty, Paul G Thomas, Liyen Loh, Katherine Kedzierska

Journal article  |  2019  |  Clinical & Translational Immunology

Influenza

F Krammer, GJD Smith, RAM Fouchier, M Peiris, K Kedzierska, PC Doherty, P Palese, ML Shaw, J Treanor, RG Webster, A García-Sastre

Journal article  |  2018  |  Nature Reviews Disease Primers

Australian health professionals' statement on climate change and health

Kerry Arabena, Fiona Armstrong, Helen Berry, Peter Brooks, Tony Capon, Brendan Crabb, Alessandro Demaio, Peter Doherty, Sharon Lewin, Selina Lo, Alan Lopez, Celia McMichael, Barbara McPake, Rob Moodie, Terry Nolan, Tilman Ruff, Peter Sainsbury, Linda Selvey, David Shearman, Fiona Stanley, et al.

Journal article  |  2018  |  The Lancet

Potential killers exposed: tracking endogenous influenza-specific CD8( ) T cells

Rachael Keating, Melissa Y Morris, Wen Yue, Cory E Reynolds, Tarsha L Harris, Scott A Brown, Peter C Doherty, Paul G Thomas, Maureen A McGargill

Journal article  |  2018  |  Immunology and Cell Biology

Age-Related Decline in Primary CD8( ) T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8( ) T Cells

Kylie M Quinn, Annette Fox, Kim L Harland, Brendan E Russ, Jasmine Li, Thi HO Nguyen, Liyen Loh, Moshe Olshanksy, Haroon Naeem, Kirill Tsyganov, Florian Wiede, Rosela Webster, Chantelle Blyth, Xavier YX Sng, Tony Tiganis, David Powell, Peter C Doherty, Stephen J Turner, Katherine Kedzierska, Nicole L La Gruta

Journal article  |  2018  |  Cell Reports

Clonally diverse CD38( )HLA-DR( )CD8( ) T cells persist during fatal H7N9 disease

Zhongfang Wang, Lingyan Zhu, Thi HO Nguyen, Yanmin Wan, Sneha Sant, Sergio M Quinones-Parra, Jeremy Chase Crawford, Auda A Eltahla, Simone Rizzetto, Rowena A Bull, Chenli Qiu, Marios Koutsakos, E Bridie Clemens, Liyen Loh, Tianyue Chen, Lu Liu, Pengxing Cao, Yanqin Ren, Lukasz Kedzierski, Tom Kotsimbos, et al.

Journal article  |  2018  |  Nature Communications

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8 T cell response magnitude

Kylie M Quinn, Wan-Ting Kan, Katherine A Watson, Brian J Liddicoat, Natasha G Swan, Hayley McQuilten, Alice E Denton, Jasmine Li, Weisan Chen, Lorena E Brown, David C Jackson, Patrick C Reading, Peter C Doherty, Katherine Kedzierska, Lukasz Kedzierski, Stephen J Turner, Nicole L La Gruta

Journal article  |  2017  |  PLOS ONE

Advancing Australia's role in climate change and health research

Donna Green, Andrew Pitman, Adrian Barnett, John Kaldor, Peter Doherty, Fiona Stanley

Journal article  |  2017  |  Nature Climate Change

Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation

Liyen Loh, Zhongfang Wang, Sneha Sant, Marios Koutsakos, Sinthujan Jegaskanda, Alexandra J Corbett, Ligong Liu, David P Fairlie, Jane Crowe, Jamie Rossjohn, Jianqing Xu, Peter C Doherty, James McCluskey, Katherine Kedzierska

Journal article  |  2016  |  Proceedings of the National Academy of Sciences

Competition within the virus-specific CD4 T-cell pool limits the T follicular helper response after influenza infection

Matthew R Olson, Brendon Y Chua, Kim L Good-Jacobson, Peter C Doherty, David C Jackson, Stephen J Turner

Journal article  |  2016  |  Immunology and Cell Biology

Molecular basis for universal HLA-A(star)0201-restricted CD8( ) T-cell immunity against influenza viruses

Sophie A Valkenburg, Tracy M Josephs, E Bridie Clemens, Emma J Grant, Thi HO Nguyen, George C Wang, David A Price, Adrian Miller, Steven YC Tong, Paul G Thomas, Peter C Doherty, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska

Journal article  |  2016  |  Proceedings of the National Academy of Sciences

Heightened self-reactivity associated with selective survival, but not expansion, of naive virus-specific CD8( ) T cells in aged mice

Kylie M Quinn, Sophie G Zaloumis, Tania Cukalac, Wan-Ting Kan, Xavier YX Sng, Michiko Mirams, Katherine A Watson, James M McCaw, Peter C Doherty, Paul G Thomas, Andreas Handel, Nicole L La Gruta

Journal article  |  2016  |  Proceedings of the National Academy of Sciences

THE RED AND WHITE: ANCIENT HISTORY

Peter Doherty

Journal article  |  2016  |  Nature Reviews Immunology

What Lies Ahead? Scientists Look into Their Crystal Balls: Pandemics: What Everyone Needs to Know

P Doherty

Book Chapter  |  2016

Sizing up the key determinants of the CD8( ) T cell response

David C Tscharke, Nathan P Croft, Peter C Doherty, Nicole L La Gruta

Journal article  |  2015  |  Nature Reviews Immunology

Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity

Brendon Y Chua, Chinn Yi Wong, Edin J Mifsud, Kathryn M Edenborough, Toshiki Sekiya, Amabel CL Tan, Francesca Mercuri, Steve Rockman, Weisan Chen, Stephen J Turner, Peter C Doherty, Anne Kelso, Lorena E Brown, David C Jackson

Journal article  |  2015  |  mBio

Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8( ) T cells

Zhongfang Wang, Yanmin Wan, Chenli Qiu, Sergio Quinones-Parra, Zhaoqin Zhu, Liyen Loh, Di Tian, Yanqin Ren, Yunwen Hu, Xiaoyan Zhang, Paul G Thomas, Michael Inouye, Peter C Doherty, Katherine Kedzierska, Jianqing Xu

Journal article  |  2015  |  Nature Communications

Evidence and the Practice of Politics

Peter Doherty

Journal article  |  2015  |  Meanjin

Fixed Expression of Single Influenza Virus-Specific TCR Chains Demonstrates the Capacity for TCR alpha- and beta-Chain Diversity in the Face of Peptide-MHC Class I Specificity

E Bridie Clemens, Peter C Doherty, Nicole L La Gruta, Stephen J Turner

Journal article  |  2015  |  The Journal of Immunology

Diverse Heterologous Primary Infections Radically Alter Immunodominance Hierarchies and Clinical Outcomes Following H7N9 Influenza Challenge in Mice

Susu Duan, Victoria A Meliopoulos, Jennifer L McClaren, Xi-Zhi J Guo, Catherine J Sanders, Heather S Smallwood, Richard J Webby, Stacey L Schultz-Cherry, Peter C Doherty, Paul G Thomas

Journal article  |  2015  |  PLOS Pathogens

Helping Themselves: Optimal Virus-Specific CD4 T Cell Responses Require Help via CD4 T Cell Licensing of Dendritic Cells

Matthew R Olson, Shirley GK Seah, Jolie Cullen, Marie Greyer, Kathryn Edenborough, Peter C Doherty, Sammy Bedoui, Andrew M Lew, Stephen J Turner

Journal article  |  2014  |  The Journal of Immunology

An open letter to the Prime Minister, the Honourable Tony Abbott, MP.

Stephen R Leeder

Journal article  |  2014  |  Medical Journal of Australia

Open letter to the Hon Tony Abbott MP.

Anthony J McMichael, Stephen R Leeder, Bruce K Armstrong, Antony Basten, Peter C Doherty, Robert M Douglas, Adele C Green, Gustav JV Nossal, David JC Shearman, Fiona J Stanley, Graham V Vimpani, Alex D Wodak

Journal article  |  2014  |  The Medical journal of Australia

CD154( ) CD4( ) T-cell dependence for effective memory influenza virus-specific CD8( ) T-cell responses

Matthew R Olson, Shirley GK Seah, Kathryn Edenborough, Peter C Doherty, Andrew M Lew, Stephen J Turner

Journal article  |  2014  |  Immunology and Cell Biology

The Influenza Virus-Specific CTL Immunodominance Hierarchy in Mice Is Determined by the Relative Frequency of High-Avidity T Cells

Tania Cukalac, Jesseka Chadderton, Weiguang Zeng, Jolie G Cullen, Wan Ting Kan, Peter C Doherty, David C Jackson, Stephen J Turner, Nicole L La Gruta

Journal article  |  2014  |  Journal of Immunology

Epigenetic plasticity of Cd8a locus during CD8( ) T-cell development and effector differentiation and reprogramming

Kim L Harland, E Bridie Day, Simon H Apte, Brendan E Russ, Peter C Doherty, Stephen J Turner, Anne Kelso

Journal article  |  2014  |  Nature Communications

Highly Pathological Influenza A Virus Infection Is Associated with Augmented Expression of PD-1 by Functionally Compromised Virus-Specific CD8( ) T Cells

John A Rutigliano, Shalini Sharma, Melissa Y Morris, Thomas H Oguin, Jennifer L McClaren, Peter C Doherty, Paul G Thomas

Journal article  |  2014  |  Journal of Virology

Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model

Carrie M Rosenberger, Rebecca L Podyminogin, Peter S Askovich, Garnet Navarro, Shari M Kaiser, Catherine J Sanders, Jennifer L McClaren, Vincent C Tam, Pradyot Dash, Jhoanna G Noonan, Bart G Jones, Sherri L Surman, Jacques J Peschon, Alan H Diercks, Julia L Hurwitz, Peter C Doherty, Paul G Thomas, Alan Aderem

Journal article  |  2014  |  Journal of General Virology

Reproducible selection of high avidity CD8( ) T-cell clones following secondary acute virus infection

Tania Cukalac, Jesseka Chadderton, Andreas Handel, Peter C Doherty, Stephen J Turner, Paul G Thomas, Nicole L La Gruta

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Preexisting CD8 T-cell immunity to the H7N9 influenza a virus varies across ethnicities

S Quiñones-Parra, E Grant, L Loh, THO Nguyen, KA Campbell, SYC Tong, A Miller, PC Doherty, D Vijaykrishna, J Rossjohn, S Gras, K Kedzierska

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Preexisting CD8( ) T-cell immunity to the H7N9 influenza A virus varies across ethnicities

Sergio Quinones-Parra, Emma Grant, Liyen Loh, Thi HO Nguyen, Kristy-Anne Campbell, Steven YC Tong, Adrian Miller, Peter C Doherty, Dhanasekaran Vijaykrishna, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection

Zhongfang Wang, Anli Zhang, Yanmin Wan, Xinian Liu, Chao Qiu, Xiuhong Xi, Yanqin Ren, Jing Wang, Yuan Dong, Meijuan Bao, Liangzhu Li, Mingzhe Zhou, Songhua Yuan, Jun Sun, Zhaoqin Zhu, Liang Chen, Qingsheng Li, Zhiyong Zhang, Xiaoyan Zhang, Shuihua Lu, et al.

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Resilient sustainable cities: A future

LJ Pearson, PW Newton, P Roberts

Book  |  2014

In conversation with Donald Hector

P Doherty

Journal article  |  2014  |  Journal and Proceedings of the Royal Society of New South Wales

The challenges to urban sustainability and resilience

PW Newton, P Doherty

Book Chapter  |  2014

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus

Rachael Keating, Tomer Hertz, Marie Wehenkel, Tarsha L Harris, Benjamin A Edwards, Jennifer L McClaren, Scott A Brown, Sherri Surman, Zachary S Wilson, Philip Bradley, Julia Hurwitz, Hongbo Chi, Peter C Doherty, Paul G Thomas, Maureen A McGargill

Journal article  |  2013  |  Nature Immunology

Acute emergence and reversion of influenza A virus quasispecies within CD8( ) Tcell antigenic peptides

Sophie A Valkenburg, Sergio Quinones-Parra, Stephanie Gras, Naomi Komadina, Jodie McVernon, Zhongfang Wang, Hanim Halim, Pina Iannello, Catherine Cole, Karen Laurie, Anne Kelso, Jamie Rossjohn, Peter C Doherty, Stephen J Turner, Katherine Kedzierska

Journal article  |  2013  |  Nature Communications

Differential Host Response, Rather Than Early Viral Replication Efficiency, Correlates with Pathogenicity Caused by Influenza Viruses

Peter S Askovich, Catherine J Sanders, Carrie M Rosenberger, Alan H Diercks, Pradyot Dash, Garnet Navarro, Peter Vogel, Peter C Doherty, Paul G Thomas, Alan Aderem

Journal article  |  2013  |  PLoS ONE

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

Christopher Lupfer, Paul G Thomas, Paras K Anand, Peter Vogel, Sandra Milasta, Jennifer Martinez, Gonghua Huang, Maggie Green, Mondira Kundu, Hongbo Chi, Ramnik J Xavier, Douglas R Green, Mohamed Lamkanfi, Charles A Dinarello, Peter C Doherty, Thirumala-Devi Kanneganti

Journal article  |  2013  |  Nature Immunology

Preemptive priming readily overcomes structure-based mechanisms of virus escape

Sophie A Valkenburg, Stephanie Gras, Carole Guillonneau, Lauren A Hatton, Nicola A Bird, Kelly-Anne Twist, Hanim Halim, David C Jackson, Anthony W Purcell, Stephen J Turner, Peter C Doherty, Jamie Rossjohn, Katherine Kedzierska

Journal article  |  2013  |  Proceedings of the National Academy of Sciences of the United States of America

Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels

Catherine J Sanders, Peter Vogel, Jennifer L McClaren, Resha Bajracharya, Peter C Doherty, Paul G Thomas

Journal article  |  2013  |  American Journal of Physiology - Lung Cellular and Molecular Physiology

Transmission Studies Resume For Avian Flu

Ron AM Fouchier, Adolfo Garcia-Sastre, Yoshihiro Kawaoka, Wendy S Barclay, Nicole M Bouvier, Ian H Brown, Ilaria Capua, Hualan Chen, Richard W Compans, Robert B Couch, Nancy J Cox, Peter C Doherty, Ruben O Donis, Heinz Feldmann, Yi Guan, Jacqueline M Katz, Oleg I Kiselev, HD Klenk, Gary Kobinger, Jinhua Liu, et al.

Journal article  |  2013  |  Science

Ecological analysis of antigen-specific CTL repertoires defines the relationship between naive and immune T-cell populations

Paul G Thomas, Andreas Handel, Peter C Doherty, Nicole L La Gruta

Journal article  |  2013  |  Proceedings of the National Academy of Sciences of the United States of America

Cell-mediated immunity

Stephen J Turner, Peter C Doherty, Anne Kelso

Book Chapter  |  2013

Unexpected rewards from reconstructing the 1918 influenza virus

JK Taubenberger, D Baltimore, PC Doherty, H Markel, DM Morens, RG Webster, IA Wilson

Journal article  |  2013  |  Microbe Magazine

Reconstruction of the 1918 Influenza Virus: Unexpected Rewards from the Past

Jeffery K Taubenberger, David Baltimore, Peter C Doherty, Howard Markel, David M Morens, Robert G Webster, Ian A Wilson

Journal article  |  2012  |  MBIO

Viral immunity and vaccine strategies

DL Woodland, GA Cole, PC Doherty

Book Chapter  |  2012

T Cell Receptor alpha beta Diversity Inversely Correlates with Pathogen-Specific Antibody Levels in Human Cytomegalovirus Infection

George C Wang, Pradyot Dash, Jonathan A McCullers, Peter C Doherty, Paul G Thomas

Journal article  |  2012  |  Science Translational Medicine

Induction of Protective CD4( ) T Cell-Mediated Immunity by a Leishmania Peptide Delivered in Recombinant Influenza Viruses

Katherine Kedzierska, Joan M Curtis, Sophie A Valkenburg, Lauren A Hatton, Hiu Kiu, Peter C Doherty, Lukasz Kedzierski

Journal article  |  2012  |  PLoS One

Dangerous for ferrets: lethal for humans?

Peter C Doherty, Paul G Thomas

Journal article  |  2012  |  BMC Biology

Early Priming Minimizes the Age-Related Immune Compromise of CD8( ) T Cell Diversity and Function

Sophie A Valkenburg, Vanessa Venturi, Thurston HY Dang, Nicola L Bird, Peter C Doherty, Stephen J Turner, Miles P Davenport, Katherine Kedzierska

Journal article  |  2012  |  PLoS Pathogens

Consequences of suboptimal priming are apparent for low-avidity T-cell responses

Vanessa Venturi, Miles P Davenport, Natasha G Swan, Peter C Doherty, Katherine Kedzierska

Journal article  |  2012  |  Immunology and Cell Biology

H5N1. Ron Fouchier: in the eye of the storm.

Ron Fouchier

Journal article  |  2012  |  Science

Pause on Avian Flu Transmission Research

Ron AM Fouchier, Adolfo Garcia-Sastre, Yoshihiro Kawaoka, Wendy S Barclay, Nicole M Bouvier, Ian H Brown, Ilaria Capua, Hualan Chen, Richard W Compans, Robert B Couch, Nancy J Cox, Peter C Doherty, Ruben O Donis, Heinz Feldmann, Yi Guan, Jaqueline Katz, HD Klenk, Gary Kobinger, Jinhua Liu, Xiufan Liu, et al.

Journal article  |  2012  |  Science

Use it or lose it: establishment and persistence of T cell memory

Katherine Kedzierska, Sophie A Valkenburg, Peter C Doherty, Miles P Davenport, Vanessa Venturi

Journal article  |  2012  |  Frontiers in Immunology

Peter Doherty (1940, Australia): Immune senescence and senescent immunologists

PC Doherty

Book  |  2012

Sentinel Chickens: What Birds Tell Us about Our Health and the World

PC Doherty

Book  |  2012

Affinity Thresholds for Naive CD8( ) CTL Activation by Peptides and Engineered Influenza A Viruses

Alice E Denton, Robb Wesselingh, Stephanie Gras, Carole Guillonneau, Matthew R Olson, Justine D Mintern, Weiguang Zeng, David C Jackson, Jamie Rossjohn, Philip D Hodgkin, Peter C Doherty, Stephen J Turner

Journal article  |  2011  |  Journal of Immunology

Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8( ) T cells

Alice E Denton, Brendan E Russ, Peter C Doherty, Sudha Rao, Stephen J Turner

Journal article  |  2011  |  Proceedings of the National Academy of Sciences of the United States of America

The Tetramer Transformation

Peter C Doherty

Journal article  |  2011  |  Journal of Immunology

Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8( ) T-cell responses

E Bridie Day, Carole Guillonneau, Stephanie Gras, Nicole L La Gruta, Dario AA Vignali, Peter C Doherty, Anthony W Purcell, Jamie Rossjohn, Stephen J Turner

Journal article  |  2011  |  Proceedings of the National Academy of Sciences of the United States of America

Effect of MHC Class I Diversification on Influenza Epitope-Specific CD8( ) T Cell Precursor Frequency and Subsequent Effector Function

E Bridie Day, Kim L Charlton, Nicole L La Gruta, Peter C Doherty, Stephen J Turner

Journal article  |  2011  |  Journal of Immunology

Systematic identification of immunodominant CD8( ) T-cell responses to influenza A virus in HLA-A2 individuals

Chao Wu, Damien Zanker, Sophie Valkenburg, Bee Tan, Katherine Kedzierska, Quan Ming Zou, Peter C Doherty, Weisan Chen

Journal article  |  2011  |  Proceedings of the National Academy of Sciences of the United States of America

Immunity to seasonal and pandemic influenza A viruses

Sophie A Valkenburg, John A Rutigliano, Ali H Ellebedy, Peter C Doherty, Paul G Thomas, Katherine Kedzierska

Journal article  |  2011  |  Microbes and Infection

Memory precursor phenotype of CD8( ) T cells reflects early antigenic experience rather than memory numbers in a model of localized acute influenza infection

Hayley A Croom, Alice E Denton, Sophie A Valkenburg, Natasha G Swan, Matthew R Olson, Stephen J Turner, Peter C Doherty, Katherine Kedzierska

Journal article  |  2011  |  European Journal of Immunology

T-cell immunity against the A(H1N1) 2009 pandemic virus

S VALKENBURG, K Laurie, A Kelso, SJT Turner, PCD Doherty, KK Kedzierska

Journal article  |  2011  |  Microbiology Australia

Respiratory epithelial cells in innate immunity to influenza virus infection

Catherine J Sanders, Peter C Doherty, Paul G Thomas

Journal article  |  2011  |  Cell and Tissue Research

Paired analysis of TCR alpha and TCR beta chains at the single-cell level in mice

Pradyot Dash, Jennifer L McClaren, Thomas H Oguin, William Rothwell, Brandon Todd, Melissa Y Morris, Jared Becksfort, Cory Reynolds, Scott A Brown, Peter C Doherty, Paul G Thomas

Journal article  |  2011  |  Journal of Clinical Investigation

The Immune Response to Influenza A Viruses

Justine D Mintern, Carole Guillonneau, Stephen J Turner, Peter C Doherty

Journal article  |  2011  |  Birkhauser Advances in Infectious Diseases

Influenza Epitope-Specific CD8( ) T Cell Avidity, but Not Cytokine Polyfunctionality, Can Be Determined by TCR beta Clonotype

Jessica M Moffat, Andreas Handel, Peter C Doherty, Stephen J Turner, Paul G Thomas, Nicole L La Gruta

Journal article  |  2010  |  Journal of Immunology

Q&A: H1N1 pandemic influenza - what's new?

Stephen J Turner, Peter C Doherty, Anne Kelso

Journal article  |  2010  |  BMC Biology

The glittering prizes

Peter C Doherty

Journal article  |  2010  |  Nature Immunology

Fixing an irrelevant TCR alpha chain reveals the importance of TCR beta diversity for optimal TCR alpha beta pairing and function of virus-specific CD8( ) T cells

Sophie A Valkenburg, E Bridie Day, Natasha G Swan, Hayley A Croom, Francis R Carbone, Peter C Doherty, Stephen J Turner, Katherine Kedzierska

Journal article  |  2010  |  European Journal of Immunology

Multiplexed combinatorial tetramer staining in a mouse model of virus infection

Tania Cukalac, Sophie A Valkenburg, Nicole L La Gruta, Stephen J Turner, Peter C Doherty, Katherine Kedzierska

Journal article  |  2010  |  Journal of Immunological Methods

Protective Efficacy of Cross-Reactive CD8( ) T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

Sophie A Valkenburg, Stephanie Gras, Carole Guillonneau, Nicole L La Gruta, Paul G Thomas, Anthony W Purcell, Jamie Rossjohn, Peter C Doherty, Stephen J Turner, Katherine Kedzierska

Journal article  |  2010  |  PLoS Pathogens

Cross- reactive CD8( ) T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses

Stephanie Gras, Lukasz Kedzierski, Sophie A Valkenburg, Karen Laurie, Yu Chih Liu, Justin T Denholm, Michael J Richards, Guus F Rimmelzwaan, Anne Kelso, Peter C Doherty, Stephen J Turner, Jamie Rossjohn, Katherine Kedzierska

Journal article  |  2010  |  Proceedings of the National Academy of Sciences of the United States of America

The Role of Epigenetics in the Acquisition and Maintenance of Effector Function in Virus-Specific CD8 T Cells

Matthew R Olson, Brendan E Russ, Peter C Doherty, Stephen J Turner

Journal article  |  2010  |  IUBMB Life

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

Nicole L La Gruta, William T Rothwell, Tania Cukalac, Natasha G Swan, Sophie A Valkenburg, Katherine Kedzierska, Paul G Thomas, Peter C Doherty, Stephen J Turner

Journal article  |  2010  |  Journal of Clinical Investigation

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

Alex Theodossis, Carole Guillonneau, Andrew Welland, Lauren K Ely, Craig S Clements, Nicholas A Williamson, Andrew I Webb, Jacqueline A Wilce, Roger J Mulder, Michelle A Dunstone, Peter C Doherty, James McCluskey, Anthony W Purcell, Stephen J Turner, Jamie Rossjohn

Journal article  |  2010  |  Proceedings of the National Academy of Sciences of the United States of America

Influenza A virus-specific CD8( ) T-cell responses: from induction to function

MR Olson, BE Russ, PC Doherty, SJ Turner, J Stambas

Journal article  |  2010  |  Future Virology

Physiological Numbers of CD4( ) T Cells Generate Weak Recall Responses Following Influenza Virus Challenge

Paul G Thomas, Scott A Brown, Melissa Y Morris, Wen Yue, Jenny So, Cory Reynolds, Richard J Webby, Peter C Doherty

Journal article  |  2010  |  Journal of Immunology

Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression (vol 183, pg 7063, 2009)

Torsten Juelich, Elissa L Sutcliffe, Alice Denton, Yiqing He, Peter C Doherty, Christopher R Parish, Stephen J Turner, David J Tremethick, Sudha Rao

Journal article  |  2010  |  The Journal of Immunology

Protective Memory Responses Are Modulated by Priming Events prior to Challenge

John A Rutigliano, Melissa Y Morris, Wen Yue, Rachael Keating, Richard J Webby, Paul G Thomas, Peter C Doherty

Journal article  |  2010  |  Journal of Virology

New Approaches in Immunotherapy

Paul G Thomas, Peter C Doherty

Journal article  |  2010  |  Science

Q&A: H1N1 pandemic influenza - what's new?

S TURNER, P DOHERTY, A KELSO

Journal article  |  2010  |  BMC Biology

Interplay between Chromatin Remodeling and Epigenetic Changes during Lineage-Specific Commitment to Granzyme B Expression

Torsten Juelich, Elissa Sutcliffe, Alice Denton, Yiqing He, Peter C Doherty, Christopher Parish, Steven J Turner, David Tremethick, Sudha Rao

Journal article  |  2009  |  Journal of Immunology

Narrowed TCR diversity for immunised mice challenged with recombinant influenza A-HIV Env(311-320) virus

Tania Cukalac, Jessica M Moffat, Vanessa Venturi, Miles P Davenport, Peter C Doherty, Stephen J Turner, John Stambas

Journal article  |  2009  |  Vaccine

P19-24. Evaluation of recombinant influenza-SIV vaccines in macaques

J Stambas, A Sexton, R De Rose, JC Reece, S Alcantara, L Loh, JM Moffat, K Laurie, A Hurt, PC Doherty, SJ Turner, SJ Kent

Journal article  |  2009  |  Retrovirology

Evaluation of Recombinant Influenza Virus-Simian Immunodeficiency Virus Vaccines in Macaques

Amy Sexton, Robert De Rose, Jeanette C Reece, Sheilajen Alcantara, Liyen Loh, Jessica M Moffat, Karen Laurie, Aeron Hurt, Peter C Doherty, Stephen J Turner, Stephen J Kent, John Stambas

Journal article  |  2009  |  Journal of Virology

Finding multiple needles in one immune haystack

Katherine Kedzierska, John Stambas, Peter C Doherty

Journal article  |  2009  |  Nature Methods

Functional implications of T cell receptor diversity

Stephen J Turner, Nicole L La Gruta, Katherine Kedzierska, Paul G Thomas, Peter C Doherty

Journal article  |  2009  |  Current Opinion in Immunology

Thinking About Broadly Cross-Reactive Vaccines

PC Doherty, SJ Turner

Journal article  |  2009  |  Clinical Pharmacology and Therapeutics

Granzyme A expression reveals distinct cytolytic CTL subsets following influenza A virus infection

Jessica M Moffat, Thomas Gebhardt, Peter C Doherty, Stephen J Turner, Justine D Mintern

Journal article  |  2009  |  European Journal of Immunology

Transience of MHC Class I-restricted antigen presentation after influenza A virus infection

Justine D Mintern, Sammy Bedoui, Gayle M Davey, Jessica M Moffat, Peter C Doherty, Stephen J Turner

Journal article  |  2009  |  Proceedings of the National Academy of Sciences of the United States of America

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

Paul G Thomas, Pradyot Dash, Jerry R Aldridge, Ali H Ellebedy, Cory Reynolds, Amy J Funk, William J Martin, Mohamed Lamkanfi, Richard J Webby, Kelli L Boyd, Peter C Doherty, Thirumala-Devi Kanneganti

Journal article  |  2009  |  Immunity

Immunity to avian influenza A viruses

PC Doherty, LE Brown, A Kelso, PG Thomas

Journal article  |  2009  |  OIE Revue Scientifique et Technique

Visualizing CTL activity for different CD8( ) effector T cells supports the idea that lower TCR/epitope avidity may be advantageous for target cell killing

MR Jenkins, NL La Gruta, PC Doherty, JA Trapani, SJ Turner, NJ Waterhouse

Journal article  |  2009  |  Cell Death & Differentiation

TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection

Jerry R Aldridge, Carson E Moseley, David A Boltz, Nicholas J Negovetich, Cory Reynolds, John Franks, Scott A Brown, Peter C Doherty, Robert G Webster, Paul G Thomas

Journal article  |  2009  |  Proceedings of the National Academy of Sciences of the United States of America

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity

Carole Guillonneau, Justine D Mintern, Francois-Xavier Hubert, Aeron C Hurt, Gurdyal S Besra, Steven Porcelli, Ian G Barr, Peter C Doherty, Dale I Godfrey, Stephen J Turner

Journal article  |  2009  |  Proceedings of the National Academy of Sciences of the United States of America

Rules to 'prime' by

Paul G Thomas, Peter C Doherty

Journal article  |  2009  |  Nature Immunology

Q&A: What do we know about influenza and what can we do about it?

P DOHERTY, S TURNER

Journal article  |  2009  |  Journal of Biology

Division-linked differentiation can account for CD8( ) T-cell phenotype in vivo

Timothy E Schlub, Vanessa Venturi, Katherine Kedzierska, Cameron Wellard, Peter C Doherty, Stephen J Turner, Ruy M Ribeiro, Philip D Hodgkin, Miles P Davenport

Journal article  |  2009  |  European Journal of Immunology

Q&A: What have we found out about the influenza A (H1N1) 2009 pandemic virus?

S TURNER, L BROWN, P DOHERTY, A Kelso

Journal article  |  2009  |  Journal of Biology

Q&A: What have we found out about the influenza A (H1N1) 2009 pandemic virus?

Stephen J Turner, Lorena E Brown, Peter C Doherty, Anne Kelso

Journal article  |  2009  |  Journal of Biology

Q&A: What do we know about influenza and what can we do about it?

Peter C Doherty, Stephen J Turner

Journal article  |  2009  |  Journal of Biology

Complete modification of TCR specificity and repertoire selection does not perturb a CD8( ) T cell immunodominance hierarchy

Katherine Kedzierska, Carole Guillonneau, Stephanie Gras, Lauren A Hatton, Richard Webby, Anthony W Purcell, Jamie Rossjohn, Peter C Doherty, Stephen J Turner

Journal article  |  2008  |  Proceedings of the National Academy of Sciences of the United States of America

Decreased IL-10 and IL-13 production and increased CD44(hi) T cell recruitment contribute to Leishmania major immunity induced by non-persistent parasites

Lukasz Kedzierski, Joan M Curtis, Peter C Doherty, Emanuela Handman, Katherine Kedzierska

Journal article  |  2008  |  European Journal of Immunology

Killer T cells in influenza

John Stambas, Carole Guillonneau, Katherine Kedzierska, Justine D Mintern, Peter C Doherty, Nicole L La Gruta

Journal article  |  2008  |  Pharmacology and Therapeutics

Sindbis virus vectors elicit hemagglutinin-specific humoral and cellular immune responses and offer a dose-sparing strategy for vaccination

Annett Miller, Rob J Center, John Stambas, Georgia Deliyannis, Peter C Doherty, Jane L Howard, Stephen J Turner, Damian FJ Purcell

Journal article  |  2008  |  Vaccine

Toward a broadly protective influenza vaccine

Peter C Doherty, Anne Kelso

Journal article  |  2008  |  Journal of Clinical Investigation

Cell cycle-related acquisition of cytotoxic mediators defines the progressive differentiation to effector status for virus-specific CD8( ) T cells

Misty R Jenkins, Justine Mintern, Nicole L La Gruta, Katherine Kedzierska, Peter C Doherty, Stephen J Turner

Journal article  |  2008  |  Journal of Immunology

Granzyme K Expressing Cytotoxic T Lymphocytes Protects Against Influenza Virus in Granzyme AB(-/-) Mice

Misty R Jenkins, Joseph A Trapani, Peter C Doherty, Stephen J Turner

Journal article  |  2008  |  Viral Immunology

Terminal deoxynucleotidyltransferase is required for the establishment of private virus-specific CD8( ) TCR repertoires and facilitates optimal CTL responses

Katherine Kedzierska, Paul G Thomas, Vanessa Venturi, Miles P Davenport, Peter C Doherty, Stephen J Turner, Nicole L La Gruta

Journal article  |  2008  |  Journal of Immunology

Screening monoclonal antibodies for cross-reactivity in the ferret model of influenza infection

John A Rutigliano, Peter C Doherty, John Franks, Melissa Y Morris, Cory Reynolds, Paul G Thomas

Journal article  |  2008  |  Journal of Immunological Methods

Homogenization of TCR repertoires within secondary CD62L(high) and CD62L(low) virus-specific CD8( ) T cell populations

Katherine Kedzierska, Vanessa Venturi, Sophie A Valkenburg, Miles P Davenport, Stephen J Turner, Peter C Doherty

Journal article  |  2008  |  Journal of Immunology

Epitope-specific TCR beta repertoire diversity imparts no functional advantage on the CD8( ) T cell response to cognate viral peptides

Nicole L La Gruta, Paul G Thomas, Andrew I Webb, Michelle A Dunstone, Tania Cukalac, Peter C Doherty, Anthony W Purcell, Jamie Rossjohn, Stephen J Turner

Journal article  |  2008  |  Proceedings of the National Academy of Sciences of the United States of America

Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity

Katherine Kedzierska, Nicole L La Gruta, John Stambas, Stephen J Turner, Peter C Doherty

Journal article  |  2008  |  Molecular Microbiology

Burnet, chick embryos, viruses, clones and quantitative biology

Peter C Doherty

Journal article  |  2008  |  Immunology and Cell Biology

The network collective: Rise and fall of a scientific paradigm

K Eichmann

Book  |  2008

Method for assessing the similarity between subsets of the T cell receptor repertoire

Vanessa Venturi, Katherine Kedzierska, Mark M Tanaka, Stephen J Turner, Peter C Doherty, Miles P Davenport

Journal article  |  2008  |  Journal of Immunological Methods

The immune response to influenza A viruses

J MINTERN, C GUILLONNEAU, S TURNER, P DOHERTY

Book Chapter  |  2008

Foreword for Volume IV

PC Doherty

Journal article  |  2007  |  The Mouse in Biomedical Research

Cutting edge: Tissue-resident memory CTL down-regulate cytolytic molecule expression following virus clearance

Justine D Mintern, Carole Guillonneau, Francis R Carbone, Peter C Doherty, Stephen J Turner

Journal article  |  2007  |  Journal of Immunology

A recombinant Sendai virus is controlled by CD4( ) effector T cells responding to a secreted human immunodeficiency virus type 1 envelope glycoprotein

Scott A Brown, Julia L Hurwitz, Amy Zirkel, Sherri Surman, Toru Takitnoto, Irina Alyrnova, Chris Coleclough, Allen Portner, Peter C Doherty, Karen S Slobod

Journal article  |  2007  |  Journal of Virology

The challenge of viral immunity

Peter C Doherty, Stephen J Turner

Journal article  |  2007  |  Immunity

The context of epitope presentation can influence functional quality of recalled influenza A virus-specific memory CD8( ) T cells

E Bridie Day, Weiguang Zeng, Peter C Doherty, David C Jackson, Katherine Kedzierska, Stephen J Turner

Journal article  |  2007  |  Journal of Immunology

Heterogeneity of effector phenotype for acute phase and memory influenza A virus-specific CTL

Misty R Jenkins, Katherine Kedzierska, Peter C Doherty, Stephen J Turner

Journal article  |  2007  |  Journal of Immunology

Disregulated influenza A virus-specific CD8( ) T cell homeostasis in the absence of IFN-gamma signaling

Stephen J Turner, Elvia Olivas, Astrid Gutierrez, Gabriela Diaz, Peter C Doherty

Journal article  |  2007  |  Journal of Immunology

Erratum: Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8 T cells with regime-dependent cytokine/granzyme B profiles (The Journal of Immunology (2007) 178 (2370-2379))

C Ranasinghe, SJ Turner, C McArthur, DB Sutherland, JH Kim, PC Doherty, IA Ramshaw

Journal article  |  2007  |  Journal of Immunology

Location rather than CD62L phenotype is critical in the early establishment of influenza-specific CD8( ) T cell memory

Katherine Kedzierska, John Stambas, Misty R Jenkins, Rachael Keating, Stephen J Turner, Peter C Doherty

Journal article  |  2007  |  Proceedings of the National Academy of Sciences of the United States of America

Methods for comparing the diversity of samples of the T cell receptor repertoire

Vanessa Venturi, Katherine Kedzierska, Stephen J Turner, Peter C Doherty, Miles P Davenport

Journal article  |  2007  |  Journal of Immunological Methods

Virus-specific CD8( ) T cells in the liver: Armed and ready to kill

Rachael Keating, Wen Yue, John A Rutigliano, Jenny So, Elvia Olivas, Paul G Thomas, Peter C Doherty

Journal article  |  2007  |  Journal of Immunology

Hidden epitopes emerge in secondary influenza virus-specific CD8( ) T cell reponses

Paul G Thomas, Scott A Brown, Rachael Keating, Wen Yue, Melissa Y Morris, Jenny So, Richard J Webby, Peter C Doherty

Journal article  |  2007  |  Journal of Immunology

Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8( ) T cells with regime-dependent cytokine/granzyme B profiles

Charani Ranasinghe, Stephen J Turner, Craig McArthur, Duncan B Sutherland, Jee-Hye Kim, Peter C Doherty, Ian A Ramshaw

Journal article  |  2007  |  Journal of Immunology

An in vivo cytotoxicity threshold for influenza A virus-specific effector and memory CD8( ) T cells

John Stambas, Peter C Doherty, Stephen J Turner

Journal article  |  2007  |  Journal of Immunology

IL-18, but not IL-12, is required for optimal cytokine production by influenza virus-specific CD8( ) T cells

Alice E Denton, Peter C Doherty, Stephen J Turner, Nicole L La Gruta

Journal article  |  2007  |  European Journal of Immunology

A question of self-preservation: immunopathology in influenza virus infection

Nicole L La Gruta, Katherine Kedzierska, John Stambas, Peter C Doherty

Journal article  |  2007  |  Immunology and Cell Biology

Challenged by complexity: My twentieth century in immunology

Peter C Doherty

Journal article  |  2007  |  Annual Review of Immunology

Crystal-ball gazing - the future of immunological research viewed from the cutting edge

L Brent, IR Cohen, PC Doherty, M Feldmann, P Matzinger, ST Holgate, P Lachmann, NA Mitchison, G Nossal, NR Rose, R Zinkernagel

Journal article  |  2007  |  Clinical and Experimental Immunology

Memories of a senior scientist - Endings and beginnings - F. M. Burnet

PC Doherty

Journal article  |  2007  |  Cellular and Molecular Life Sciences

Sharing of T cell receptors in antigen-specific responses is driven by convergent recombination

Vanessa Venturi, Katherine Kedzierska, David A Price, Peter C Doherty, Daniel C Douek, Stephen J Turner, Miles P Davenport

Journal article  |  2006  |  Proceedings of the National Academy of Sciences of the United States of America

Structural determinants of T-cell receptor bias in immunity

Stephen J Turner, Peter C Doherty, James McCluskey, Jamie Rossjohn

Journal article  |  2006  |  Nature Reviews Immunology

Immunoproteasome subunit deficiencies impact differentially on two immunodominant influenza-virus-specific CD8( ) T cell responses

Ken C Pang, Megan T Sanders, John J Monaco, Peter C Doherty, Stephen J Turner, Weisan Chen

Journal article  |  2006  |  The Journal of Immunology

Preparing for an influenza pandemic

Peter C Doherty

Journal article  |  2006  |  MEDICAL JOURNAL OF AUSTRALIA

Editorial

PC Doherty

Journal article  |  2006  |  Medical Journal of Australia

Quantification of repertoire diversity of influenza-specific epitopes with predominant public or private TCR usage

Katherine Kedzierska, E Bridie Day, Jing Pi, Stephen B Heard, Peter C Doherty, Stephen J Turner, Stanley Perlman

Journal article  |  2006  |  Journal of Immunology

A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8( ) T cell responses

Nicole L La Gruta, Peter C Doherty, Stephen J Turner

Journal article  |  2006  |  European Journal of Immunology

Addition of a prominent epitope affects influenza a virus-specific CD8( ) T cell immunodominance hierarchies when antigen is limiting

Misty Rayna Jenkins, Richard Webby, Peter C Doherty, Stephen J Turner

Journal article  |  2006  |  Journal of Immunology

Early establishment of diverse T cell receptor profiles for influenza-specific CD8( )CD62L(hi) memory T cells

Katherine Kedzierska, Vanessa Venturi, Kenneth Field, Miles P Davenport, Stephen J Turner, Peter C Doherty

Journal article  |  2006  |  Proceedings of the National Academy of Sciences of the United States of America

Establishment and recall of CD8( ) T-cell memory in a model of localized transient infection

Katherine Kedzierska, Nicole L La Gruta, Stephen J Turner, Peter C Doherty

Journal article  |  2006  |  Immunological Reviews

Influenza and the challenge for immunology

PC Doherty, SJ Turner, RG Webby, PG Thomas

Journal article  |  2006  |  Nature Immunology

An unexpected antibody response to an engineered influenza virus modifies CD8( ) T cell responses

PG Thomas, SA Brown, W Yue, J So, RJ Webby, PC Doherty

Journal article  |  2006  |  Proceedings of the National Academy of Sciences of the United States of America

A virus-specific CD8( ) T cell immunodominance hierarchy determined by antigen dose and precursor frequencies

NL La Gruta, K Kedzierska, K Pang, M Davenport, WS Chen, SJ Turner, PC Doherty

Journal article  |  2006  |  Proceedings of the National Academy of Sciences of the United States of America

Immunoproteasome Subunit Deficiencies Impact Differentially on Two Immunodominant Influenza Virus-Specific CD8 T Cell Respones1

C pang, T saunders, J monaco, P DOHERTY, S TURNER, W CHEN

Journal article  |  2006  |  Immunology

Olfaction and the Brain Foreword

Peter C Doherty

Book  |  2006

Cell-mediated protection in influenza infection

PG Thomas, R Keating, DJ Hulse-Post, PC Doherty

Journal article  |  2006  |  Emerging Infectious Diseases

Preparing for an Influenza Pandemic

P DOHERTY

Journal article  |  2006  |  Medical Journal of Australia

U Thant lecture: Science, society and the challenge of the future

PC Doherty

Journal article  |  2005  |  Notes and Records of the Royal Society

Contribution of T cell receptor affinity to overall avidity for virus-specific CD8( ) T cell responses

K Kedzierska, NL La Gruta, MP Davenport, SJ Turner, PC Doherty

Journal article  |  2005  |  Proceedings of the National Academy of Sciences of the United States of America

CD8 T-cells: are they sufficient to prevent, contain or eradicate HIV-1 infection?

Scott A Brown, Julia L Hurwitz, Xiaoyan Zhan, Peter C Doherty, Karen S Slobod

Journal article  |  2005  |  Current Drug Targets

The prevention of HIV-1 by vaccination has proven to be a formidable task. In an ongoing endeavor to end the HIV-1 pandemic, scien..

Effector CD8( ) T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression

DR Marshall, E Olivas, S Andreansky, NL La Gruta, GA Neale, A Gutierrez, DG Wichlan, S Wingo, C Cheng, PC Doherty, SJ Turner

Journal article  |  2005  |  Proceedings of the National Academy of Sciences of the United States of America

HIV vaccine rationale, design and testing

KS Slobod, C Coleclough, M Bonsignori, SA Brown, XY Zhan, S Surman, A Zirkel, BG Jones, RE Sealy, J Stambas, B Brown, TD Lockey, PJ Freiden, PC Doherty, JL Blanchard, LN Martin, JL Hurwitz

Journal article  |  2005  |  Current HIV Research

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8( ) T cell populations

SJ Turner, K Kedzierska, H Komodromou, NL La Gruta, MA Dunstone, AI Webb, R Webby, H Walden, WD Xie, J McCluskey, AW Purcell, J Rossjohn, PC Doherty

Journal article  |  2005  |  Nature Immunology

WASP(-) mice exhibit defective immune responses to influenza A virus, Streptococcus pneumoniae, and Mycobacterium bovis BCG

S Andreansky, HY Liu, S Turner, JA McCullers, R Lang, R Rutschman, PC Doherty, PJ Murray, AW Nienhuis, TS Strom

Journal article  |  2005  |  Experimental Hematology

Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8( )-T-cell responses

SS Andreansky, J Stambas, PG Thomas, WD Xie, RJ Webby, PC Doherty

Journal article  |  2005  |  Journal of Virology

Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses

AS Lipatov, S Andreansky, RJ Webby, DJ Hulse, JE Rehg, S Krauss, DR Perez, PC Doherty, RG Webster, MY Sangster

Journal article  |  2005  |  Journal of General Virology

Long lived multi-isotype anti-HIV antibody responses following a prime-double boost immunization strategy.

J Stambas, SA Brown, A Gutierrez, R Sealy, W Yue, B Jones, TD Lockey, A Zirkel, P Freiden, B Brown, S Surman, C Coleclough, KS Slobod, PC Doherty, JL Hurwitz

Journal article  |  2005  |  Vaccine

Long lived multi-isotype anti-HIV antibody responses following a prime-double boost immunization strategy

J Stambas, SA Brown, A Gutierrez, R Sealy, W Yue, B Jones, TD Lockey, A Zirkel, P Freiden, B Brown, S Surman, C Coleclough, KS Slobod, PC Doherty, JL Hurwitz

Journal article  |  2005  |  Vaccine

T cell epitope "hotspots" on the HIV type 1 gp120 envelope protein overlap with tryptic fragments displayed by mass spectrometry

SA Brown, TD Lockey, C Slaughter, KS Slobod, S Surman, A Zirkel, A Mishra, VR Pagala, C Coleclough, PC Doherty, JL Hurwitz

Journal article  |  2005  |  AIDS Research and Human Retroviruses

The virus-immunity ecosystem

PC Doherty, SJ Turner

Journal article  |  2005  |  Archives of Virology

Characterization of CD8( ) T cell repertoire diversity and persistence in the influenza A virus model of localized, transient infection

SJ Turner, K Kedzierska, NL La Gruta, R Webby, PC Doherty

Journal article  |  2004  |  Science

Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8( ) T cell responses: Correlation of cytokine profile and TCR avidity

NL La Gruta, SJ Turner, PC Doherty

Journal article  |  2004  |  Journal of Immunology

Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope

K Kedzierska, SJ Turner, PC Doherty

Journal article  |  2004  |  Proceedings of the National Academy of Sciences of the United States of America

Memories of virus-specific CD8( ) T cells

PC Doherty, SJ Turner

Journal article  |  2004  |  Immunology and Cell Biology

Differential tumor necrosis factor receptor 2-mediated editing of virus-specific CD8( ) effector T cells

SJ Turner, NL La Gruta, J Stambas, G Diaz, PC Doherty

Journal article  |  2004  |  Proceedings of the National Academy of Sciences of the United States of America

The limits of protection by "memory" T cells in Ig(-/-) mice persistently infected with a gamma-herpesvirus

S Andreansky, HY Liu, H Adler, UH Koszinowski, S Efstathiou, PC Doherty

Journal article  |  2004  |  Proceedings of the National Academy of Sciences of the United States of America

The collagen binding alpha 1 beta 1 integrin VLA-1 regulates CD8 T cell-mediated immune protection against heterologous influenza infection

SJ Ray, SN Franki, RH Pierce, S Dimitrova, V Koteliansky, AG Sprague, PC Doherty, AR de Fougerolles, DJ Topham

Journal article  |  2004  |  Immunity

Subcutaneous administration of a recombinant vaccinia virus vaccine expressing multiple envelopes of HIV-1

KS Slobod, TD Lockey, N Howlett, RV Srinivas, SD Rencher, PJ Freiden, PC Doherty, JL Hurwitz

Journal article  |  2004  |  European Journal of Clinical Microbiology & Infectious Diseases

Overcoming diversity with a multi-envelope HIV vaccine

undefined Slobod, undefined Brown, undefined Surman, undefined Zirkel, undefined Jones, undefined Zhan, undefined Sealy, J STAMBAS, undefined Brown, undefined Coleclough, P DOHERTY, undefined Hurwitz, undefined Freiden, undefined Lockey, undefined Bonsigniori

Journal article  |  2004  |  Current Topics in Virology

Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2

N Carpino, S Turner, D Mekala, Y Takahashi, HS Zang, TL Geiger, P Doherty, JN Ihle

Journal article  |  2004  |  Immunity

On the nose: shared themes for the sensory and immune self

PC Doherty

Journal article  |  2003  |  Nature Immunology

Defects in T-cell-mediated immunity to influenza virus in murine Wiskott-Aldrich syndrome are corrected by oncoretroviral vector-mediated gene transfer into repopulating hematopoietic cells

TS Strom, SJ Turner, S Andreansky, HY Liu, PC Doherty, DK Srivastava, JM Cunningham, AW Nienhuis

Journal article  |  2003  |  Blood

Defects in T-cell-mediated immunity to influenza virus in murine Wiskott-Aldrich syndrome are corrected by oncoretroviral vector-mediated gene transfer into repopulating hematopoietic cells

TS Strom, SJ Turner, S Andreansky, H Liu, PC Doherty, DK Srivastava, JM Cunningham, AW Nienhuis

Journal article  |  2003  |  Blood

Abstract The Wiskott-Aldrich syndrome (WAS) is an X-linked disorder characterized by immune dysfunction, thrombocyt..

Clustering of Th cell epitopes on exposed regions of HIV envelope despite defects in antibody activity

SA Brown, J Stambas, XY Zhan, KS Slobod, C Coleclough, A Zirkel, S Surman, SW White, PC Doherty, JL Hurwitz

Journal article  |  2003  |  Journal of Immunology

An early CD4( ) T cell-dependent immunoglobulin A response to influenza infection in the absence of key cognate T-B interactions

MY Sangster, JM Riberdy, M Gonzalez, DJ Topham, N Baumgarth, PC Doherty

Journal article  |  2003  |  Journal of Experimental Medicine

Differential antigen presentation regulates the changing patterns of CD8( ) T cell immunodominance in primary and secondary influenza virus infections

SR Crowe, SJ Turner, SC Miller, AD Roberts, RA Rappolo, PC Doherty, KH Ely, DL Woodland

Journal article  |  2003  |  Journal of Experimental Medicine

Host-pathogen interactions Host defense against microbial pathogens - the immune system's weapons of mass destruction

RL Modlin, P Doherty

Journal article  |  2003  |  Current Opinion in Immunology

Quantitative analysis of long-term virus-specific CD8( )-T-cell memory in mice challenged with unrelated pathogens

HY Liu, S Andreansky, G Diaz, SJ Turner, D Wodarz, PC Doherty

Journal article  |  2003  |  Journal of Virology

Protection and compensation in the influenza virus-specific CD8 T cell response

RJ Webby, S Andreansky, J Stambas, JE Rehg, RG Webster, PC Doherty, SJ Turner

Journal article  |  2003  |  Proceedings of the National Academy of Sciences of the United States of America

Limited breadth of a T-helper cell response to a human immunodeficiency virus envelope protein

X Zhan, KS Slobod, S Surman, SA Brown, TD Lockey, C Coleclough, PC Doherty, JL Hurwitz

Journal article  |  2003  |  Journal of Virology

Analysis of clonotype distribution and persistence for an influenza virus-specific CD8( ) T cell response

SJ Turner, G Diaz, R Cross, PC Doherty

Journal article  |  2003  |  Immunity

Absence of a functional defect in CD T cells during primary murine gammaherpesvirus-68 infection of I-A (b-/-) mice

GT Belz, HY Liu, S Andreansky, PC Doherty, PG Stevenson

Journal article  |  2003  |  Journal of General Virology

Compromised influenza virus-specific CD8( )-T-Cell memory in CD4( )-T-cell-deficient mice

GT Belz, D Wodarz, G Diaz, MA Nowak, PC Doherty

Journal article  |  2002  |  Journal of Virology

A five-residue HIV envelope helper T cell determinant: Does this peptide-MHC interaction leave the binding groove half empty?

TD Lockey, S Surman, S Brown, KS Slobod, C Coleclough, PC Doherty, JL Hurwitz

Journal article  |  2002  |  AIDS Research and Human Retroviruses

The pas de deux of viruses and CD8 T cells

PC Doherty

Journal article  |  2002  |  Immunological Reviews

Reduced functional capacity of CD8( ) T cells expanded by post-exposure vaccination of gamma-herpesvirus-infected CD4-deficient mice

HY Liu, S Andreansky, G Diaz, T Hogg, PC Doherty

Journal article  |  2002  |  Journal of Immunology

Single cell analysis of virus-specific primary and secondary responding CD8 T cell repertoires: Stochastic selection of the secondary repertoire from the memory pool.

SJ Turner, G Diaz, R Cross, PC Doherty

Journal article  |  2002  |  FASEB JOURNAL

The role of antigen in the localization of naive, acutely activated, and memory CD8( ) T cells to the lung during influenza pneumonia

DJ Topham, MR Castrucci, FS Wingo, GT Belz, PC Doherty

Journal article  |  2001  |  Journal of Immunology

Cutting edge: Culture with high doses of viral peptide induces previously unprimed CD8( ) T cells to produce cytokine

JM Riberdy, A Zirkel, S Surman, JL Hurwitz, PC Doherty

Journal article  |  2001  |  Journal of Immunology

Concurrent naive and memory CD8( ) T cell responses to an influenza A virus

SJ Turner, R Cross, WD Xie, PC Doherty

Journal article  |  2001  |  Journal of Immunology

Analysis of virus-specific CD4( ) T cells during long-term gammaherpesvirus infection

E Flano, DL Woodland, MA Blackman, PC Doherty

Journal article  |  2001  |  Journal of Virology

Erratum: Diversity of epitope and cytokine profiles for primary and secondary influenza A virus-specific CD8 T cell responses (Journal of Immunology (2001) 166 (4627-4633))

GT Belz, W Xie, PC Doherty

Journal article  |  2001  |  Journal of Immunology

Perforin and Fas in murine gammaherpesvirus-specific CD8( ) T cell control and morbidity

DJ Topham, RC Cardin, JP Christensen, JW Brooks, GT Belz, PC Doherty

Journal article  |  2001  |  Journal of General Virology

Measuring the diaspora for virus-specific CD8( ) T cells

DR Marshall, SJ Turner, GT Belz, S Wingo, S Andreansky, MY Sangster, JM Riberdy, TB Liu, M Tan, PC Doherty

Journal article  |  2001  |  Proceedings of the National Academy of Sciences of the United States of America

Virus-specific and bystander CD8( ) T-cell proliferation in the acute and persistent phases of a gammaherpesvirus infection

GT Belz, PC Doherty

Journal article  |  2001  |  Journal of Virology

Dissecting the host response to a gamma-herpesvirus

PC Doherty, JP Christensen, GT Belz, PG Stevenson, MY Sangster

Journal article  |  2001  |  Royal Society of London. Proceedings B. Biological Sciences

Localization of CD4( ) T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processing

S Surman, TD Lockey, KS Slobod, B Jones, JM Riberdy, SW White, PC Doherty, JL Hurwitz

Journal article  |  2001  |  Proceedings of the National Academy of Sciences of the United States of America

Diversity of epitope and cytokine profiles for primary and secondary influenza A virus-specific CD8( ) T cell responses

GT Belz, WD Xie, PC Doherty

Journal article  |  2001  |  Journal of Immunology

Direct effects of selective type 5 phosphodiesterase inhibitors alone or with other vasodilators on the erectile response in cats

PC Doherty, TJ Bivalacqua, HC Champion, PJ Kadowitz, B Greenwood-Van Meerveld, I Berzetei-Gurske, WJG Hellstrom

Journal article  |  2001  |  Journal of Urology

Perforin and Fas in murine gammaherpesvirus-specific CD8 T cell control and morbidity

DJ Topham, RC Cardin, JP Christensen, JW Brooks, GT Belz, PC Doherty

Journal article  |  2001  |  Journal of General Virology

Profound protection against respiratory challenge with a lethal H7N7 influenza A virus by increasing the magnitude of CD8( ) T-cell memory

JP Christensen, PC Doherty, KC Branum, JM Riberdy

Journal article  |  2000  |  Journal of Virology

Diminished primary and secondary influenza virus-specific CD8( ) T-cell responses in CD4-depleted Ig(-/-) mice

JM Riberdy, JP Christensen, K Branum, PC Doherty

Journal article  |  2000  |  Journal of Virology

Contemporary analysis of MHC-related immunodominance hierarchies in the CD8( ) T cell response to influenza A viruses

GT Belz, PG Stevenson, PC Doherty

Journal article  |  2000  |  The Journal of Immunology

Quantitative analysis of the CD8( ) T-cell response to readily eliminated and persistent viruses

PC Doherty, JM Riberdy, GT Belz

Journal article  |  2000  |  Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences

Inhibition of MHC class I-restricted antigen presentation by gamma 2-herpesviruses

PG Stevenson, S Efstathiou, PC Doherty, PJ Lehner

Journal article  |  2000  |  Proceedings of the National Academy of Sciences

A previously unrecognized H-2D(b)-restricted peptide prominent in the primary influenza A virus-specific CD8( ) T-cell response is much less apparent following secondary challenge

GT Belz, WD Xie, JD Altman, PC Doherty

Journal article  |  2000  |  Journal of Virology

Introduction

AJ McMichael, PC Doherty

Journal article  |  2000  |  Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences

The terminology problem for T cells: a discussion paper

PC Doherty

Journal article  |  2000  |  Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences

Postexposure vaccination massively increases the prevalence of gamma-herpesvirus-specific CD8( ) T cells but confers minimal survival advantage on CD4-deficient mice

GT Belz, PG Stevenson, MR Castrucci, JD Altman, PC Doherty

Journal article  |  2000  |  Proceedings of the National Academy of Sciences

Analysis of the virus-specific and nonspecific B cell response to a persistent B-lymphotropic gammaherpesvirus

MY Sangster, DJ Topham, S D'Costa, RD Cardin, TN Marion, LK Myers, PC Doherty

Journal article  |  2000  |  The Journal of Immunology

Accessing complexity: The dynamics of virus-specific T cell responses

PC Doherty, JP Christensen

Journal article  |  2000  |  Annual Review of Immunology

Requirement for CD40 ligand, CD4( ) T cells, and B cells in an infectious mononucleosis-like syndrome

JW Brooks, AM Hamilton-Easton, JP Christensen, RD Cardin, CL Hardy, PC Doherty

Journal article  |  1999  |  Journal of Virology

Reconstitution of early lymphoid proliferation and immune function in Jak3-deficient mice by interleukin-3

MP Brown, T Nosaka, RA Tripp, J Brooks, JMA van Deursen, MK Brenner, PC Doherty, JN Ihle

Journal article  |  1999  |  Blood

Turnover of T cells in murine gammaherpesvirus 68-infected mice

AM Hamilton-Easton, JP Christensen, PC Doherty

Journal article  |  1999  |  Journal of Virology

A gamma-herpesvirus sneaks through a CD8( ) T cell response primed to a lytic-phase epitope

PG Stevenson, GT Belz, MR Castrucci, JD Altman, PC Doherty

Journal article  |  1999  |  Proceedings of the National Academy of Sciences

In vivo proliferation of naive and memory influenza-specific CD8( ) T cells

KJ Flynn, JM Riberdy, JP Christensen, JD Altman, PC Doherty

Journal article  |  1999  |  Proceedings of the National Academy of Sciences

Viral studies illuminate the nature of immunity

PC Doherty

Journal article  |  1999  |  ASM NEWS

Quantitative analysis of the acute and long-term CD4( ) T-cell response to a persistent gammaherpesvirus

JP Christensen, PC Doherty

Journal article  |  1999  |  Journal of Virology

CD4( ) T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-gamma

JP Christensen, RD Cardin, KC Branum, PC Doherty

Journal article  |  1999  |  Proceedings of the National Academy of Sciences

Changing patterns of dominance in the CD8( ) T cell response during acute and persistent murine gamma-herpesvirus infection

PG Stevenson, GT Belz, JD Altman, PC Doherty

Journal article  |  1999  |  European Journal of Immunology

Burnet oration: Living in the Burnet lineage

PC Doherty

Journal article  |  1999  |  Immunology and Cell Biology

Protection against a lethal avian influenza A virus in a mammalian system

JM Riberdy, KJ Flynn, J Stech, RG Webster, JD Altman, PC Doherty

Journal article  |  1999  |  Journal of Virology

Immunological control of a murine gammaherpesvirus independent of CD8( ) T cells

PG Stevenson, RD Cardin, JP Christensen, PC Doherty

Journal article  |  1999  |  Journal of General Virology

Non-antigen-specific B-cell activation following murine gammaherpesvirus infection is CD4 independent in vitro but CD4 dependent in vivo

PG Stevenson, PC Doherty

Journal article  |  1999  |  Journal of Virology

Virus-specific immunity after gene therapy in a murine model of severe combined immunodeficiency

KD Bunting, KJ Flynn, JM Riberdy, PC Doherty, BP Sorrentino

Journal article  |  1999  |  Proceedings of the National Academy of Sciences

Dealing with virus infections

PC Doherty

Journal article  |  1999  |  BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE

Virus-specific CD8( ) T cell numbers are maintained during gamma-herpesvirus reactivation in CD4-deficient mice

PG Stevenson, GT Belz, JD Altman, PC Doherty

Journal article  |  1998  |  Proceedings of the National Academy of Sciences

Characteristics of virus-specific CD8( ) T cells in the liver during the control and resolution phases of influenza pneumonia

GT Belz, JD Altman, PC Doherty

Journal article  |  1998  |  Proceedings of the National Academy of Sciences

Thymic lymphoproliferative disease after successful correction of CD40 ligand deficiency by gene transfer in mice

MP Brown, DJ Topham, MY Sangster, JF Zhao, KJ Flynn, SL Surman, DL Woodland, PC Doherty, AG Farr, PK Pattengale, MK Brenner

Journal article  |  1998  |  Nature Medicine

Longitudinal analysis of the acute Sendai virus-specific CD4( ) T cell response and memory

DJ Topham, PC Doherty

Journal article  |  1998  |  Journal of Immunology

Pathogenesis of murine gammaherpesvirus-68 infection in interleukin-6-deficient mice

SR Sarawar, JW Brooks, RD Cardin, M Mehrpooya, PC Doherty

Journal article  |  1998  |  Virology

The continuing revolution in virus-specific CD8( )T cell-mediated immunity

PC Doherty, GT Belz, KJ Flynn

Journal article  |  1998  |  Immunologist

The new numerology of immunity mediated by virus-specific CD8( ) T cells

PC Doherty

Journal article  |  1998  |  Current Opinion in Microbiology

Virus-specific CD8( ) T cells in primary and secondary influenza pneumonia

KJ Flynn, GT Belz, JD Altman, R Ahmed, DL Woodland, PC Doherty

Journal article  |  1998  |  Immunity

Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells

AE Tollefson, TW Hermiston, DL Lichtenstein, CF Colle, RA Tripp, T Dimitrov, K Toth, CE Wells, PC Doherty, WSM Wold

Journal article  |  1998  |  Nature

Antiviral cytotoxic activity across a species barrier in mixed xenogeneic chimeras: Functional restriction to host MHC

YL Colson, RA Tripp, PC Doherty, SM Wren, M Neipp, AYA El-Ezz, ST Ildstad

Journal article  |  1998  |  Journal of Immunology

Update: Immunology - The numbers game for virus-specific CD8( ) T cells

PC Doherty

Journal article  |  1998  |  Science

Kinetic analysis of the specific host response to a murine gammaherpesvirus

PG Stevenson, PC Doherty

Journal article  |  1998  |  Journal of Virology

Clearance of an influenza A virus by CD4( ) T cells is inefficient in the absence of B cells

DJ Topham, PC Doherty

Journal article  |  1998  |  Journal of Virology

CD8 T cell-mediated immunity in acute and persistent virus infections

PC Doherty

Journal article  |  1998  |  Central-European Journal of Immunology

Cell mediated immunity in virus infections

PC Doherty

Journal article  |  1997  |  SCANDINAVIAN JOURNAL OF IMMUNOLOGY

CD8( ) T cells clear influenza virus by perforin or Fas-dependent processes

DJ Topham, RA Tripp, PC Doherty

Journal article  |  1997  |  Journal of Immunology

Consequences of viral infections for lymphocyte compartmentalization and homeostasis.

PC Doherty, AM Hamilton-Easton, DJ Topham, J Riberdy, JW Brooks, RD Cardin

Journal article  |  1997  |  Seminars in Immunology

The immune system has evolved to deal with pathogens. Analysing what happens during the course of infectious processes provides in..

Restoration of lymphopoiesis in Jak3 deficient scid mice with IL-3.

MP Brown, T Nosaka, RA Tripp, J Brooks, JMA vanDeursen, MK Brenner, PC Doherty, JN Ihle

Journal article  |  1997  |  BLOOD

Cell-mediated immunity in virus infections

PC Doherty

Journal article  |  1997  |  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Effector CD4( ) and CD8( ) T-cell mechanisms in the control of respiratory virus infections

PC Doherty, DJ Topham, RA Tripp, RD Cardin, JW Brooks, PG Stevenson

Journal article  |  1997  |  Immunological Reviews

Immunological control of murine gammaherpesvirus infection is independent of perforin

EJ Usherwood, JW Brooks, SR Sarawar, RD Cardin, WD Young, DJ Allen, PC Doherty, AA Nash

Journal article  |  1997  |  Journal of General Virology

Immunity to infection - Editorial overview

SHE Kaufmann, PC Doherty

Journal article  |  1997  |  Current Opinion in Immunology

Cell mediated immunity in virus infections (Reprinted)

PC Doherty

Journal article  |  1997  |  Bioscience Reports

Tuning into immunological dissonance: an experimental model for infectious mononucleosis

PC Doherty, RA Tripp, AM HamiltonEaston, RD Cardin, DL Woodland, MA Blackman

Journal article  |  1997  |  Current Opinion in Immunology

Pathogenesis of an infectious mononucleosis-like disease induced by a murine gamma-herpesvirus: Role for a viral superantigen?

RA Tripp, AM HamiltonEaston, RD Cardin, P Nguyen, FG Behm, DL Woodland, PC Doherty, MA Blackman

Journal article  |  1997  |  The Journal of Experimental Medicine

Gamma interferon is not essential for recovery from acute infection with murine gammaherpesvirus 68

SR Sarawar, RD Cardin, JW Brooks, M Mehrpooya, AM HamiltonEaston, XY Mo, PC Doherty

Journal article  |  1997  |  Journal of Virology

Bone marrow can function as a lymphoid organ during a primary immune response under conditions of disrupted lymphocyte trafficking

RA Tripp, DJ Topham, SR Watson, PC Doherty

Journal article  |  1997  |  Journal of Immunology

Modification of the Sendai virus-specific antibody and CD8( ) T-cell responses in mice homozygous for disruption of the interleukin-4 gene

XY Mo, MY Sangster, RA Tripp, PC Doherty

Journal article  |  1997  |  Journal of Virology

The cytotoxic T-lymphocyte response to Sendai virus is unimpaired in the absence of gamma interferon

XY Mo, RA Tripp, MY Sangster, PC Doherty

Journal article  |  1997  |  Journal of Virology

The discovery of MHC restriction

RM Zinkernagel, PC Doherty

Journal article  |  1997  |  Immunology Today

Cell-Mediated Immunity in Virus Infections (Nobel Lecture)

PC Doherty

Journal article  |  1997  |  Angewandte Chemie International Edition in English

Lethal synergism between influenza infection and staphylococcal enterotoxin B in mice

WJ Zhang, S Sarawar, P Nguyen, K Daly, JE Rehg, PC Doherty, DL Woodland, MA Blackman

Journal article  |  1996  |  Journal of Immunology

Cytotoxic T cell effector and memory function in viral immunity

PC Doherty

Journal article  |  1996  |  Current Topics in Microbiology and Immunology

Quantitative analysis of the influenza virus-specific CD4( ) T cell memory in the absence of B cells and Ig

DJ Topham, RA Tripp, AM HamiltonEaston, SR Sarawar, PC Doherty

Journal article  |  1996  |  Journal of Immunology

Progressive loss of CD8( ) T cell-mediated control of a gamma-herpesvirus in the absence of CD4( ) T cells

RD Cardin, JW Brooks, SR Sarawar, PC Doherty

Journal article  |  1996  |  The Journal of Experimental Medicine

Recombinant polyepitope vaccines for the delivery of multiple CD8 cytotoxic T cell epitopes

SA Thomson, SL Elliott, MA Sherritt, KW Sproat, BEH Coupar, AA Scalzo, CA Forbes, AM Ladhams, XY Mo, RA Tripp, PC Doherty, DJ Moss, A Suhrbier

Journal article  |  1996  |  Journal of Immunology

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

WE Thierfelder, JM vanDeursen, K Yamamoto, RA Tripp, SR Sarawar, RT Carson, MY Sangster, DAA Vignali, PC Doherty, GC Grosveld, JN Ihle

Journal article  |  1996  |  Nature

Cytokine production in the immune response to murine gammaherpesvirus 68

SR Sarawar, RD Cardin, JW Brooks, M Mehrpooya, RA Tripp, PC Doherty

Journal article  |  1996  |  Journal of Virology

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

K Shimoda, J vanDeursen, MY Sangster, SR Sarawar, RT Carson, RA Tripp, C Chu, FW Quelle, T Nosaka, DAA Vignali, PC Doherty, G Grosveld, WE Paul, JN Ihle

Journal article  |  1996  |  Nature

Establishment and persistence of virus-specific CD4( ) and CD8( ) T cell memory

PC Doherty, DJ Topham, RA Tripp

Journal article  |  1996  |  Immunological Reviews

Establishment and persistence of virus-specific CD4 and CD8 T cell memory.

PC Doherty, DJ Topham, RA Tripp

Journal article  |  1996  |  Immunological Reviews

Immune CD4( ) T cells promote the clearance of influenza virus from major histocompatibility complex class II -/- respiratory epithelium

DJ Topham, RA Tripp, SR Sarawar, MY Sangster, PC Doherty

Journal article  |  1996  |  Journal of Virology

Cytotoxic T cell effector and memory function in viral immunity

PC Doherty

Book  |  1996  |  Current Topics in Microbiology and Immunology

Selective response of gamma delta T-cell hybridomas to orthomyxovirus-infected cells

S Ponniah, PC Doherty, M Eichelberger

Journal article  |  1996  |  Journal of Virology

DEFECTIVE LYMPHOID DEVELOPMENT IN MICE LACKING JAK3

T NOSAKA, JMA VANDEURSEN, RA TRIPP, WE THIERFELDER, BA WITTHUHN, AP MCMICKLE, PC DOHERTY, GC GROSVELD, JN IHLE

Journal article  |  1995  |  Science

MOUSE MODEL FOR THE LYSOSOMAL DISORDER GALACTOSIALIDOSIS AND CORRECTION OF THE PHENOTYPE WITH OVEREXPRESSING ERYTHROID PRECURSOR CELLS

XY ZHOU, H MORREAU, R ROTTIER, D DAVIS, E BONTEN, N GILLEMANS, D WENGER, FG GROSVELD, P DOHERTY, K SUZUKI, GC GROSVELD, A DAZZO

Journal article  |  1995  |  Genes & Development

LOSER LIGHT SUICIDE OF PROLIFERATING VIRUS-SPECIFIC CD8( ) T-CELLS IN AN IN-VIVO RESPONSE

RA TRIPP, JM LAHTI, PC DOHERTY

Journal article  |  1995  |  JOURNAL OF IMMUNOLOGY

Laser light suicide of proliferating virus-specific CD8 T cells in an in vivo response.