Peter Angus

Liver-Targeted Angiotensin Converting Enzyme 2 Therapy Inhibits Chronic Biliary Fibrosis in Multiple Drug-Resistant Gene 2-Knockout Mice

Indu G Rajapaksha, Lakmie S Gunarathne, Khashayar Asadi, Sharon C Cunningham, Alexandra Sharland, Ian E Alexander, Peter W Angus, Chandana B Herath

Journal article  |  2019  |  Hepatology Communications

Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products

Dinali H Fernando, Josephine M Forbes, Peter W Angus, Chandana B Herath

Journal article  |  2019  |  International Journal of Molecular Sciences

Non-alcoholic fatty liver disease (NAFLD) affects up to 30% of the adult population and is now a major cause of liver disease-rela..

Management of Patients With Erythropoietic Protoporphyria-Related Progressive Liver Disease

Zaid S Ardalan, Sujievvan Chandran, Abhinav Vasudevan, Peter W Angus, Andrew Grigg, Simon He, Graeme A Macdonald, Simone I Strasser, Courtney J Tate, Glen A Kennedy, Adam G Testro, Paul J Gow

Journal article  |  2019  |  Liver Transplantation

Blockade of Mas Receptor or Mas-Related G-Protein Coupled Receptor Type D Reduces Portal Pressure in Cirrhotic but Not in Non-cirrhotic Portal Hypertensive Rats

Lakmie S Gunarathne, Peter W Angus, Chandana B Herath

Journal article  |  2019  |  Frontiers in Physiology

Handgrip Strength Adds More Prognostic Value to the Model for End-Stage Liver Disease Score Than Imaging-Based Measures of Muscle Mass in Men With Cirrhosis

Marie Sinclair, Brooke Chapman, Rudolf Hoermann, Peter W Angus, Adam Testro, Thomas Scodellaro, Paul J Gow

Journal article  |  2019  |  Liver Transplantation

BACKGROUND: Sarcopenia is associated with mortality in cirrhosis but there is no gold standard for its diagnosis. The comparative ..

Epidemiology and outcomes of acute liver failure in Australia

Penelope Hey, Timothy P Hanrahan, Marie Sinclair, Adam G Testro, Peter W Angus, Adam Peterson, Stephen Warrillow, Rinaldo Bellomo, Marcos Perini, Graham Starkey, Robert M Jones, Michael Fink, Tess McClure, Paul Gow

Journal article  |  2019  |  World Journal of Hepatology

Use of Dual X-ray Absorptiometry in men with advanced cirrhosis to predict sarcopenia-associated mortality risk

Marie Sinclair, Rudolf Hoermann, Adam Peterson, Adam Testro, Peter W Angus, Penelope Hey, Brooke Chapman, Paul J Gow

Journal article  |  2019  |  Liver International

Successful liver transplantation in common variable immune deficiency with reversal of hepatopulmonary syndrome.

Ross Apostolov, Marie Sinclair, Julie Lokan, Peter Angus

Journal article  |  2019  |  BMJ Case Reports

Common variable immune deficiency (CVID) is a primary immunodeficiency disorder that is associated with abnormal liver function te..

Reproductive Endocrinology of Nonalcoholic Fatty Liver Disease

Mathis Grossmann, Margaret E Wierman, Peter Angus, David J Handelsman

Journal article  |  2019  |  Endocrine Reviews

IMPACT OF CARDIOVASCULAR RISK FACTORS ON SURVIVAL AFTER LIVER TRANSPLANTATION: RESULTS FROM A PROSPECTIVE BINATIONAL MULTICENTRE REGISTRY

Anoop Ninan Koshy, HM Omar Farouque, Jay Ramchand, Hui-Chen Han, Benjamin Cailes, Mandy Byrne, Adam Testro, Robert M Jones, Jithin Sajeev, Han Lim, Peter W Angus, David Clark, Matias B Yudi, Paul J Gow

Conference Proceedings  |  2019  |  Journal of the American College of Cardiology

Human genomics of acute liver failure due to hepatitis B virus infection: An exome sequencing study in liver transplant recipients

Samira Asgari, Nimisha Chaturvedi, Petar Scepanovic, Christian Hammer, Nasser Semmo, Emiliano Giostra, Beat Muellhaupt, Peter Angus, Alexander J Thompson, Darius Moradpour, Jacques Fellay

Journal article  |  2019  |  Journal of Viral Hepatitis

Current therapies and novel approaches for biliary diseases.

Indu G Rajapaksha, Peter W Angus, Chandana B Herath

Journal article  |  2019  |  World Journal of Gastrointestinal Pathophysiology

Chronic liver diseases that inevitably lead to hepatic fibrosis, cirrhosis and/or hepatocellular carcinoma have become a major cau..

The Effects of Diabetes and High-Fat Diet on Polymodal Nociceptor and Cold Thermoreceptor Nerve Terminal Endings in the Corneal Epithelium

Abdulhakeem S Alamri, James A Brock, Chandana B Herath, Indu G Rajapaksha, Peter W Angus, Jason J Ivanusic

Journal article  |  2019  |  Investigative Opthalmology & Visual Science

Increasing Incidence of Nonalcoholic Steatohepatitis as an Indication for Liver Transplantation in Australia and New Zealand.

Luis Calzadilla-Bertot, Gary P Jeffrey, Bryon Jacques, Geoffrey McCaughan, Michael Crawford, Peter Angus, Robert Jones, Edward Gane, Stephen Munn, Graeme Macdonald, Jonathan Fawcett, Alan Wigg, John Chen, Michael Fink, Leon A Adams

Journal article  |  2019  |  Liver Transplantation

The worldwide increase in obesity and diabetes has led to predictions that nonalcoholic steatohepatitis (NASH) will become the lea..

Outcome of Acetaminophen-Induced Acute Liver Failure Managed Without Intracranial Pressure Monitoring or Transplantation

Jennifer Porteous, Luca Cioccari, Paolo Ancona, Eduardo Osawa, Kelly Jones, Paul Gow, Peter Angus, Stephen Warrillow, Rinaldo Bellomo

Journal article  |  2019  |  Liver Transplantation

Long-term safety and efficacy of tenofovir disoproxil fumarate substitution for hepatitis B immunoglobulin following liver transplantation

Abhinav Vasudevan, Zaid S Ardalan, Navera Ahmed, Ross Apostolov, Paul J Gow, Adam G Testro, Ed J Gane, Peter W Angus

Journal article  |  2018  |  JGH Open

Exploring the feasibility of targeted chronic hepatitis B screening in the emergency department: A pilot study

Catherine Brock, Yuan Yi, Timothy Papaluca, Benjamin Lucas, Peter W Angus, David Taylor, Christopher Leung

Journal article  |  2018  |  Emergency Medicine Australasia

Glecaprevir/Pibrentasvir Treatment in Liver or Kidney Transplant Patients With Hepatitis C Virus Infection

Nancy Reau, Paul Y Kwo, Susan Rhee, Robert S Brown, Kosh Agarwal, Peter Angus, Edward Gane, Jia-Horng Kao, Parvez S Mantry, David Mutimer, K Rajender Reddy, Tram T Tran, Yiran B Hu, Abhishek Gulati, Preethi Krishnan, Emily O Dumas, Ariel Porcalla, Nancy S Shulman, Wei Liu, Suvajit Samanta, et al.

Journal article  |  2018  |  Hepatology

Early viral-specific T-cell testing predicts late cytomegalovirus reactivation following liver transplantation

S Sood, C Haifer, L Yu, J Pavlovic, PJ Gow, RM Jones, K Visvanathan, PW Angus, AG Testro

Journal article  |  2018  |  Transplant Infectious Disease

Salvage Therapy with Sofosbuvir, Elbasvir, Grazoprevir and Ribavirin for Daa Non-Responders - High Efficacy in GT3 and GT1/4 HCV Infection

Tim Papaluca, Susanne Glasgow, Kate New, Anne Craigie, Lucy McDonald, Lisa Stothers, David Iser, Paul Desmond, Sally Bell, Barbara Demediuk, Kumar Visvanathan, Marno Ryan, Jessica Howell, Thai Hong, Catherine Croagh, Marie Sinclair, Peter W Angus, Niranjan Arachchi, Jacinta O'Keefe, Scott Bowden, et al.

Conference Proceedings  |  2018  |  HEPATOLOGY

Safety and effectiveness of umbilical hernia repair in patients with cirrhosis

S Hew, W Yu, S Robson, G Starkey, A Testro, M Fink, P Angus, P Gow

Journal article  |  2018  |  Hernia

Effects of angiotensin-(1-7) and angiotensin II on vascular tone in human cirrhotic splanchnic vessels

Stephen Casey, Chandana Herath, Indu Rajapaksha, Robert Jones, Peter Angus

Journal article  |  2018  |  Peptides

The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice

Indu G Rajapaksha, Kai Y Mak, Ping Huang, Louise M Burrell, Peter W Angus, Chandana B Herath

Journal article  |  2018  |  Scientific Reports

Malnutrition is Associated with Poor Outcomes after Liver Transplantation: A Promising Target for Pre-Transplantation Nutritional Intervention

Su Kah Goh, Brooke Chapman, Sarah Romero, Peter Angus, Robert Jones, Christopher Christophi, Vijayaragavan Muralidharan, Adam Testro

Conference Proceedings  |  2018  |  Transplantation

Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD

Eveline Bruinstroop, Rinkoo Dalan, Yang Cao, Yong Mong Bee, Kurumbian Chandran, Li Wei Cho, Shui Boon Soh, Eng Kiong Teo, Sue-Anne Toh, Melvin Khee Shing Leow, Rohit A Sinha, Suresh Anand Sadananthan, Navin Michael, Heather M Stapleton, Christopher Leung, Peter W Angus, Sheila K Patel, Louise M Burrell, Su Chi Lim, Chee Fang Sum, et al.

Journal article  |  2018  |  The Journal of Clinical Endocrinology & Metabolism

Sofosbuvir and daclatasvir therapy in patients with hepatitis C-related advanced decompensated liver disease (MELD >= 15)

GW McCaughan, PA Thwaites, SK Roberts, SI Strasser, J Mitchell, B Morales, S Mason, P Gow, A Wigg, C Tallis, G Jeffrey, J George, AJ Thompson, FC Parker, PW Angus

Journal article  |  2018  |  Alimentary Pharmacology & Therapeutics

Effect of Hepatic Impairment on the Pharmacokinetics of Grazoprevir, a Hepatitis C Virus Protease Inhibitor

Luzelena Caro, Larissa Wenning, Zifang Guo, Iain P Fraser, Christine Fandozzi, Jennifer Talaty, Deborah Panebianco, Maureen Ho, Naoto Uemura, Christina Reitmann, Peter Angus, Edward Gane, Thomas Marbury, William B Smith, Marian Iwamoto, Joan R Butterton, Wendy W Yeh

Journal article  |  2017  |  Antimicrobial Agents and Chemotherapy

Early radiological intervention and haematology screening is associated with excellent outcomes in Budd-Chiari syndrome

Allison Mo, Adam Testro, Janine French, Marcus Robertson, Peter Angus, Andrew Grigg

Journal article  |  2017  |  Internal Medicine Journal

Glycation: a new hope in targeting hepatocellular carcinoma?

Christopher Leung, Peter W Angus, Josephine M Forbes

Journal article  |  2017  |  Translational Cancer Research

Increased liver AGEs induce hepatic injury mediated through an OST48 pathway

Aowen Zhuang, Felicia Yt Yap, Clinton Bruce, Chris Leung, Manuel R Plan, Mitchell A Sullivan, Chandana Herath, Domenica McCarthy, Karly C Sourris, Phillip Kantharidis, Melinda T Coughlan, Mark A Febbraio, Mark P Hodson, Matthew J Watt, Peter Angus, Benjamin L Schulz, Josephine M Forbes

Journal article  |  2017  |  Scientific Reports

Regression of Hepatocellular Adenomas and Systemic Inflammatory Syndrome After Cessation of Estrogen Therapy

Marie Sinclair, Anthony Schelleman, Daljean Sandhu, Peter W Angus

Journal article  |  2017  |  Hepatology

Five-year efficacy and safety of tenofovir-based salvage therapy for patients with chronic hepatitis B who previously failed LAM/ADV therapy

Lucy Lim, Alexander Thompson, Scott Patterson, Jacob George, Simone Strasser, Alice Lee, William Sievert, Amanda Nicoll, Paul Desmond, Stuart Roberts, Kaye Marion, Scott Bowden, Stephen Locarnini, Peter Angus

Journal article  |  2017  |  Liver International

Antibiotic Allergy Labels in a Liver Transplant Recipient Study

S Khumra, J Chan, K Urbancic, T Worland, P Angus, R Jones, ML Grayson, JA Trubiano

Journal article  |  2017  |  Antimicrobial Agents and Chemotherapy

Coagulation in acutely ill patients with severe chronic liver disease: Insights from thromboelastography

Patryck Lloyd-Donald, Abhinav Vasudevan, Peter Angus, Paul Gow, Johan Martensson, Neil Glassford, Glenn M Eastwood, Graeme K Hart, Rinaldo Bellomo

Journal article  |  2017  |  Journal of Critical Care

A novel immune function biomarker identifies patients at risk of clinical events early following liver transplantation

Siddharth Sood, Craig Haifer, Lijia Yu, Julie Pavlovic, Leonid Churilov, Paul J Gow, Robert M Jones, Peter W Angus, Kumar Visvanathan, Adam G Testro

Journal article  |  2017  |  Liver Transplantation

Elastosis perforans serpiginosa in a patient with Wilson's disease

Phoebe A Thwaites, Saad A Khan, Khashayar Asadi, Peter W Angus

Journal article  |  2017  |  The Lancet Gastroenterology & Hepatology

Medical resource utilization and costs among Australian patients with genotype 1 chronic hepatitis C: results of a retrospective observational study

Heather J McElroy, Stuart K Roberts, Alex J Thompson, Peter W Angus, Sarah Jane McKenna, Emma Warren, Sharon Musgrave

Journal article  |  2017  |  Journal of Medical Economics

The Adeno-associated Virus - A Safe and Promising Vehicle for Liver-specific Gene Therapy of Inherited and Non-inherited Disorders

Kai Y Mak, Indu G Rajapaksha, Peter W Angus, Chandana B Herath

Journal article  |  2017  |  Current Gene Therapy

Immune function biomarker QuantiFERON-monitor is associated with infection risk in cirrhotic patients

Siddharth Sood, Lijia Yu, Kumar Visvanathan, Peter William Angus, Paul John Gow, Adam Gareth Testro

Journal article  |  2016  |  World Journal of Hepatology

High circulating oestrone and low testosterone correlate with adverse clinical outcomes in men with advanced liver disease

Marie Sinclair, Paul J Gow, Peter W Angus, Rudolf Hoermann, David J Handelsman, Gary Wittert, Sean Martin, Mathis Grossmann

Journal article  |  2016  |  Liver International

Low Serum Testosterone Is Associated With Adverse Outcome in Men With Cirrhosis Independent of the Model for End-Stage Liver Disease Score

Marie Sinclair, Paul J Gow, Mathis Grossmann, Adam Shannon, Rudolf Hoermann, Peter W Angus

Journal article  |  2016  |  LIVER TRANSPLANTATION

Testosterone therapy increases muscle mass in men with cirrhosis and low testosterone: A randomised controlled trial

Marie Sinclair, Mathis Grossmann, Rudolf Hoermann, Peter W Angus, Paul J Gow

Journal article  |  2016  |  Journal of Hepatology

Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease

Christopher Leung, Chandana B Herath, Zhiyuan Jia, Sof Andrikopoulos, Bronwyn E Brown, Michael J Davies, Leni R Rivera, John B Furness, Josephine M Forbes, Peter W Angus

Journal article  |  2016  |  World Journal of Gastroenterology

Acute oesophageal necrosis

Saad A Khan, Phoebe A Thwaites, Michael Braude, Steve Lontos, Peter W Angus

Journal article  |  2016  |  The Lancet Gastroenterology & Hepatology

Hepatitis C-induced hepatocyte apoptosis following liver transplantation is enhanced by immunosuppressive agents

EJ Lim, R Chin, U Nachbur, J Silke, Z Jia, PW Angus, J Torresi

Journal article  |  2016  |  Journal of Viral Hepatitis

Short article: Faldaprevir, deleobuvir and ribavirin in IL28B non-CC patients with HCV genotype-1a infection included in the SOUND-C3 phase 2b study.

Stefan Zeuzem, Parvez Mantry, Vicente Soriano, Robert J Buynak, Jean-François Dufour, Paul J Pockros, David Wright, Peter Angus, Maria Buti, Jerry O Stern, Werner Kadus, Richard Vinisko, Wulf Böcher, Federico J Mensa

Journal article  |  2016  |  European Journal of Gastroenterology & Hepatology

BACKGROUND: SOUND-C3 was a multicentre, open-label, phase 2b study exploring the safety and efficacy of the interferon-free combin..

Single-Molecule Sequencing Reveals Complex Genome Variation of Hepatitis B Virus during 15 Years of Chronic Infection following Liver Transplantation

BD Betz-Stablein, A Toepfer, M Littlejohn, L Yuen, D Colledge, V Sozzi, P Angus, A Thompson, P Revill, N Beerenwinkel, N Warner, F Luciani

Journal article  |  2016  |  Journal of Virology

The role of the gut microbiota in NAFLD

Christopher Leung, Leni Rivera, John B Furness, Peter W Angus

Journal article  |  2016  |  Nature Reviews Gastroenterology & Hepatology

Outpatient Terlipressin Infusion for the Treatment of Refractory Ascites

Paul J Gow, Zaid S Ardalan, Abhinav Vasudevan, Adam G Testro, Bei Ye, Peter W Angus

Journal article  |  2016  |  American Journal of Gastroenterology

Efficacy of outpatient continuous terlipressin infusions for hepatorenal syndrome.

Abhinav Vasudevan, Zaid Ardalan, Paul Gow, Peter Angus, Adam Testro

Journal article  |  2016  |  Hepatology

Liver Failure Complicating a Febrile Illness in a Middle-Aged Man.

Abhinav Vasudevan, Zaid Ardalan, Peter Angus

Journal article  |  2016  |  Gastroenterology

Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial.

Michael Manns, Didier Samuel, Edward J Gane, David Mutimer, Geoff McCaughan, Maria Buti, Martín Prieto, José Luis Calleja, Markus Peck-Radosavljevic, Beat Müllhaupt, Kosh Agarwal, Peter Angus, Eric M Yoshida, Massimo Colombo, Mario Rizzetto, Hadas Dvory-Sobol, Jill Denning, Sarah Arterburn, Phillip S Pang, Diana Brainard, et al.

Journal article  |  2016  |  The Lancet Infectious Diseases

BACKGROUND: Treatment options are limited for patients infected by hepatitis C virus (HCV) with advanced liver disease. We assesse..

Risk stratification in acute upper GI bleeding: comparison of the AIMS65 score with the Glasgow-Blatchford and Rockall scoring systems

Marcus Robertson, Avik Majumdar, Ray Boyapati, William Chung, Tom Worland, Ryma Terbah, James Wei, Steve Lontos, Peter Angus, Rhys Vaughan

Journal article  |  2016  |  Gastrointestinal Endoscopy

Additive impact of pre-liver transplant metabolic factors on survival post-liver transplant

Leon A Adams, Oscar Arauz, Peter W Angus, Marie Sinclair, Graeme A MacDonald, Utti Chelvaratnam, Alan J Wigg, Sze Yeap, Nicholas Shackel, Linda Lin, Spiro Raftopoulos, Geoffrey W McCaughan, Gary P Jeffrey

Journal article  |  2016  |  Journal of Gastroenterology and Hepatology

Daclatasvir, sofosbuvir, and ribavirin for hepatitis C virus genotype 3 and advanced liver disease: A randomized phase III study (ALLY-3 )

Vincent Leroy, Peter Angus, Jean-Pierre Bronowicki, Gregory J Dore, Christophe Hezode, Stephen Pianko, Stanislas Pol, Katherine Stuart, Edmund Tse, Fiona McPhee, Rafia Bhore, Maria Jesus Jimenez-Exposito, Alexander J Thompson

Journal article  |  2016  |  Hepatology

Review article: sarcopenia in cirrhosis - aetiology, implications and potential therapeutic interventions

M Sinclair, PJ Gow, M Grossmann, PW Angus

Journal article  |  2016  |  Alimentary Pharmacology & Therapeutics

Low testosterone as a better predictor of mortality than sarcopenia in men with advanced liver disease

Marie Sinclair, Mathis Grossmann, Peter W Angus, Rudolf Hoermann, Penelope Hey, Thomas Scodellaro, Paul J Gow

Journal article  |  2016  |  Journal of Gastroenterology and Hepatology

The increasing burden of potentially preventable liver disease among adult liver transplant recipients: A comparative analysis of liver transplant indication by era in Australia and New Zealand

Jessica Howell, Glenda Balderson, Margaret Hellard, Paul Gow, Simone Strasser, Katherine Stuart, Alan Wigg, Gary Jeffrey, Ed Gane, Peter W Angus

Journal article  |  2016  |  Journal of Gastroenterology and Hepatology

Circulating CD147 predicts mortality in advanced hepatocellular carcinoma

Aimei Lee, Anthony Rode, Amanda Nicoll, Annette E Maczurek, Lucy Lim, Seok Lim, Peter Angus, Ian Kronborg, Niranjan Arachchi, Alexandra Gorelik, Danny Liew, Fiona J Warner, Geoffrey W McCaughan, Susan V McLennan, Nicholas A Shackel

Journal article  |  2016  |  Journal of Gastroenterology and Hepatology

Resolution of norfloxacin-induced acute liver failure after N-acetylcysteine therapy: further support for the use of NAC in drug-induced ALF?

Timothy Ross Elliott, Tiffany Symes, George Kannourakis, Peter Angus

Journal article  |  2016  |  BMJ Case Reports

Liver injury due to idiosyncratic drug reactions can be difficult to diagnose and may lead to acute liver failure (ALF), which has..

Macrophage activation marker soluble CD163 may predict disease progression in hepatocellular carcinoma

Konstantin Kazankov, Anthony Rode, Kira Simonsen, Gerda Elisabeth Villadsen, Amanda Nicoll, Holger Jon Moller, Lucy Lim, Peter Angus, Ian Kronborg, Niranjan Arachchi, Alexandra Gorelik, Danny Liew, Hendrik Vilstrup, Jan Frystyk, Henning Gronbaek

Journal article  |  2016  |  Scandinavian Journal of Clinical and Laboratory Investigation

Incretin-based therapies for the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis

Laura J Carbone, Peter W Angus, Neville D Yeomans

Journal article  |  2016  |  Journal of Gastroenterology and Hepatology

Targeted Individual Prophylaxis Offers Superior Risk Stratification for Cytomegalovirus Reactivation After Liver Transplantation

Siddharth Sood, Craig Haifer, Lijia Yu, Julie Pavlovic, Paul J Gow, Robert M Jones, Kumar Visvanathan, Peter W Angus, Adam G Testro

Journal article  |  2015  |  Liver Transplantation

Hemodynamic Effects of the Non-Peptidic Angiotensin-(1-7) Agonist AVE0991 in Liver Cirrhosis

Sabine Klein, Chandana B Herath, Robert Schierwagen, Josephine Grace, Tom Haltenhof, Frank E Uschner, Christian P Strassburg, Tilman Sauerbruch, Thomas Walther, Peter W Angus, Jonel Trebicka

Journal article  |  2015  |  PLOS ONE

Effect of Immunosuppressive Agents on Hepatocyte Apoptosis Post-Liver Transplantation

Eu Jin Lim, Ruth Chin, Ueli Nachbur, John Silke, Zhiyuan Jia, Peter W Angus, Joseph Torresi

Journal article  |  2015  |  PLOS ONE

Upregulation of circulating components of the alternative renin-angiotensin system in inflammatory bowel disease: A pilot study

Mayur Garg, Louise M Burrell, Elena Velkoska, Karen Griggs, Peter W Angus, Peter R Gibson, John S Lubel

Journal article  |  2015  |  Journal of the Renin-Angiotensin-Aldosterone System

ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice

Kai Y Mak, Ruth Chin, Sharon C Cunningham, Miriam R Habib, Joseph Torresi, Alexandra F Sharland, Ian E Alexander, Peter W Angus, Chandana B Herath

Journal article  |  2015  |  Molecular Therapy

An autosomal dominant form of non-cirrhotic portal hypertension

Avik Majumdar, Martin B Delatycki, Peter Crowley, Julie Lokan, Benjamin Tharian, Peter W Angus, Paul Gow

Journal article  |  2015  |  Journal of Hepatology

Risk factors for band-induced ulcer bleeding after prophylactic and therapeutic endoscopic variceal band ligation

Marie Sinclair, Rhys Vaughan, Peter W Angus, Paul J Gow, Frank Parker, Penelope Hey, Marios Efthymiou

Journal article  |  2015  |  European Journal of Gastroenterology & Hepatology

Increased aortic intimal proliferation due to MasR deletion in vitro

Hiba Alsaadon, Peter Kruzliak, Arthur Smardencas, Alan Hayes, Michael Bader, Peter Angus, Chandana Herath, Anthony Zulli

Journal article  |  2015  |  International Journal of Experimental Pathology

Fixed-Dose Combination Therapy With Daclatasvir, Asunaprevir, and Beclabuvir for Noncirrhotic Patients With HCV Genotype 1 Infection

Fred Poordad, William Sievert, Lindsay Mollison, Michael Bennett, Edmund Tse, Norbert Braeu, James Levin, Thomas Sepe, Samuel S Lee, Peter Angus, Brian Conway, Stanislas Pol, Nathalie Boyer, Jean-Pierre Bronowicki, Ira Jacobson, Andrew J Muir, K Rajender Reddy, Edward Tam, Grisell Ortiz-Lasanta, Victor de Ledinghen, et al.

Journal article  |  2015  |  JAMA

Role of the Alternate RAS in Liver Disease and the GI Tract

CB Herath, KY Mak, PW Angus

Book Chapter  |  2015

Efficacy and safety of faldaprevir, deleobuvir, and ribavirin in treatment-naive patients with chronic hepatitis C virus infection and advanced liver fibrosis or cirrhosis.

Stefan Zeuzem, Vicente Soriano, Tarik Asselah, Edward J Gane, Jean-Pierre Bronowicki, Peter Angus, Ansgar W Lohse, Felix Stickel, Beat Müllhaupt, Stuart Roberts, Marcus Schuchmann, Michael Manns, Marc Bourlière, Maria Buti, Jerry O Stern, John-Paul Gallivan, Florian Voss, John P Sabo, Wulf Böcher, Federico J Mensa, et al.

Journal article  |  2015  |  Antimicrobial Agents and Chemotherapy

Patients with advanced hepatic fibrosis or cirrhosis with chronic hepatitis C virus (HCV) infection represent an unmet need. The H..

Testosterone in men with advanced liver disease: Abnormalities and implications

Marie Sinclair, Mathis Grossmann, Paul J Gow, Peter W Angus

Journal article  |  2015  |  Journal of Gastroenterology and Hepatology

Laboratory Identification of Donor-Derived Coxsackievirus B3 Transmission

IJ Abbott, G Papadakis, M Kaye, H Opdam, H Hutton, PW Angus, PDR Johnson, J Kanellis, G Westall, J Druce, M Catton

Journal article  |  2015  |  American Journal of Transplantation

Characteristics of hepatocellular carcinoma in cirrhotic and non-cirrhotic non-alcoholic fatty liver disease

Christopher Leung, Sern Wei Yeoh, Desmond Patrick, Shara Ket, Kaye Marion, Paul Gow, Peter W Angus

Journal article  |  2015  |  World Journal of Gastroenterology

Low-Serum Testosterone Levels Pre-Liver Transplantation Are Associated With Reduced Rates of Early Acute Allograft Rejection in Men

Marie Sinclair, Peter W Angus, Paul J Gow, Rudolf Hoermann, Tamara Mogilevski, Mathis Grossmann

Journal article  |  2014  |  Transplantation

Liver transplantation for the treatment of homozygous familial hypercholesterolaemia in an era of emerging lipid-lowering therapies (vol 44, pg 601, 2014)

MM Page, EI Ekinci, RM Jones, PW Angus, PJ Gow, RC O'Brien

Journal article  |  2014  |  Internal Medicine Journal

Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis

Eu Jin Lim, Korri El Khobar, Ruth Chin, Linda Earnest-Silveira, Peter W Angus, C-Thomas Bock, Ueli Nachbur, John Silke, Joseph Torresi

Journal article  |  2014  |  Journal of General Virology

Vitamin B₁₂ and its binding proteins in hepatocellular carcinoma and chronic liver diseases.

Kira Simonsen, Anthony Rode, Amanda Nicoll, Gerda Villadsen, Ulrick Espelund, Lucy Lim, Peter Angus, Niranjan Arachchi, Hendrik Vilstrup, Ebba Nexo, Henning Grønbæk

Journal article  |  2014  |  Scandinavian Journal of Gastroenterology

BACKGROUND: The vitamin B12 (B12)-binding protein haptocorrin (HC) has proven to be a potentially useful biomarker in patients wit..

Education and Imaging. Hepatobiliary and pancreatic: systemic mastocytosis with portal hypertension.

D Wong, R Boyapati, J Lokan, P Angus

Journal article  |  2014  |  Journal of Gastroenterology and Hepatology

Damage to enteric neurons occurs in mice that develop fatty liver disease but not diabetes in response to a high-fat diet

LR Rivera, C Leung, RV Pustovit, BL Hunne, S Andrikopoulos, C Herath, A Testro, PW Angus, JB Furness

Journal article  |  2014  |  Neurogastroenterology & Motility

Liver transplantation for the treatment of homozygous familial hypercholesterolaemia in an era of emerging lipid-lowering therapies

MM Page, EI Ekinci, RM Jones, PW Angus, PJ Gow, RC O'Brien

Journal article  |  2014  |  Internal Medicine Journal

A randomized controlled study of trimethoprim-sulfamethoxazole versus norfloxacin for the prevention of infection in cirrhotic patients

Steve Lontos, Edward Shelton, Peter W Angus, Rhys Vaughan, Stuart K Roberts, Adam Gordon, Paul J Gow

Journal article  |  2014  |  Journal of Digestive Diseases

A Novel Biomarker of Immune Function and Initial Experience in a Transplant Population

Siddharth Sood, Diana Cundall, Lijia Yu, Misato Miyamasu, Jefferey S Boyle, Sim Y Ong, Paul J Gow, Robert M Jones, Peter W Angus, Kumar Visvanathan, Adam G Testro

Journal article  |  2014  |  Transplantation

Muscle Mass and Mortality in Chronic Liver Disease: The Impact of Testosterone

Marie Sinclair, Peter W Angus, Mathis Grossmann, Paul J Gow

Journal article  |  2014  |  Liver Transplantation

Dietary glycotoxins exacerbate progression of experimental fatty liver disease

Christopher Leung, Chandana B Herath, Zhiyuan Jia, Michelle Goodwin, Kai Yan Mak, Matthew J Watt, Josephine M Forbes, Peter W Angus

Journal article  |  2014  |  Journal of Hepatology

Role of toll-like receptors in liver transplantation

Jessica Howell, Paul Gow, Peter Angus, Kumar Visvanathan

Journal article  |  2014  |  Liver Transplantation

Acute Hepatic Decompensation Precipitated by Pregnancy-Related Catabolic Stress A Rare Mimic of Acute Liver Failure

Marie Sinclair, Shara Ket, Adam Testro, Paul J Gow, Peter W Angus

Journal article  |  2014  |  Obstetrics & Gynecology

Hepatitis C recurrence: the Achilles heel of liver transplantation

J Howell, P Angus, P Gow

Journal article  |  2014  |  Transplant Infectious Disease

Recurrence of hepatopulmonary syndrome post-orthotopic liver transplantation in a patient with noncirrhotic portal hypertension.

Stephen Casey, Anthony Schelleman, Peter Angus

Journal article  |  2013  |  Hepatology

Identifying the superior measure of rapid fibrosis for predicting premature cirrhosis after liver transplantation for hepatitis C

J Howell, R Sawhney, P Angus, M Fink, R Jones, BZ Wang, K Visvanathan, P Crowley, P Gow

Journal article  |  2013  |  Transplant Infectious Disease

Post-Liver Transplant Leptin Results in Resolution of Severe Recurrence of Lipodystrophy-Associated Nonalcoholic Steatohepatitis

SP Casey, J Lokan, A Testro, S Farquharson, A Connelly, J Proietto, PW Angus

Journal article  |  2013  |  American Journal of Transplantation

Profiles of perfluoroalkyl substances in the liver and serum of patients with liver cancer and cirrhosis in Australia

Leo WY Yeung, Keerthi S Guruge, Sachi Taniyasu, Nobuyoshi Yamashita, Peter W Angus, Chandana B Herath

Journal article  |  2013  |  Ecotoxicology and Environmental Safety

Cyclosporine and Tacrolimus Have Inhibitory Effects on Toll-Like Receptor Signaling After Liver Transplantation

Jessica Howell, Rohit Sawhney, Adam Testro, Narelle Skinner, Paul Gow, Peter Angus, Dilip Ratnam, Kumar Visvanathan

Journal article  |  2013  |  Liver Transplantation

Activation of the Mas Receptor by Angiotensin-(1-7) in the Renin-Angiotensin System Mediates Mesenteric Vasodilatation in Cirrhosis

Josephine A Grace, Sabine Klein, Chandana B Herath, Michaela Granzow, Robert Schierwagen, Noemi Masing, Thomas Walther, Tilman Sauerbruch, Louise M Burrell, Peter W Angus, Jonel Trebicka

Journal article  |  2013  |  Gastroenterology

Electronic Estimations of Renal Function Are Inaccurate in Solid-Organ Transplant Recipients and Can Result in Significant Underdosing of Prophylactic Valganciclovir

J Trevillyan, P Angus, E Shelton, J Whitlam, F Ierino, J Pavlovic, D Gregory, K Urbancic, J Torresi, A Testro, ML Grayson

Journal article  |  2013  |  Antimicrobial Agents and Chemotherapy

Erratum: Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction (Journal of Pharmacology and Experimental Therapeutics (2013) 344 (388-396))

T Nishimura, Y Hu, M Wu, E Pham, H Suemizu, M Elazar, M Liu, R Idilman, C Yurdaydin, P Angus, C Stedman, B Murphy, J Glenn, M Nakamura, T Nomura, Y Chen, M Zheng, WL Fitch, G Peltz

Journal article  |  2013  |  Journal of Pharmacology and Experimental Therapeutics

Toll-like receptors in hepatitis C infection: Implications for pathogenesis and treatment

Jessica Howell, Peter Angus, Paul Gow, Kumar Visvanathan

Journal article  |  2013  |  Journal of Gastroenterology and Hepatology

Toll-Like Receptor 3 and 7/8 Function Is Impaired in Hepatitis C Rapid Fibrosis Progression Post-Liver Transplantation

J Howell, R Sawhney, N Skinner, P Gow, P Angus, D Ratnam, K Visvanathan

Journal article  |  2013  |  American Journal of Transplantation

To TOE or not to TOE? That is the question in patients with portal hypertension and varices

Christopher Leung, Sern Wei Yeoh, Lucy Y Lim, Ray Boyapati, Adam G Testro, Rhys Vaughan, Kaye Marion, Louise M Burrell, Peter WAngus

Journal article  |  2013  |  Gut

Combination of lamivudine and adefovir without hepatitis B immune globulin is safe and effective prophylaxis against hepatitis B virus recurrence in hepatitis B surface antigenpositive liver transplant candidates

Edward J Gane, Scott Patterson, Simone I Strasser, Geoffrey W McCaughan, Peter W Angus

Journal article  |  2013  |  Liver Transplantation

Therapeutic potential of targeting the renin angiotensin system in portal hypertension.

Chandana B Herath, Josephine A Grace, Peter W Angus

Journal article  |  2013  |  World Journal of Gastrointestinal Pathophysiology

Portal hypertension is responsible for the bulk of the morbidity and mortality in patients with cirrhosis. Drug therapy to reduce ..

Using Chimeric Mice with Humanized Livers to Predict Human Drug Metabolism and a Drug-Drug Interaction

Toshiko Nishimura, Yajing Hu, Manhong Wu, Edward Pham, Hiroshi Suemizu, Menashe Elazar, Michael Liu, Ramazan Idilman, Cihan Yurdaydin, Peter Angus, Catherine Stedman, Brian Murphy, Jeffrey Glenn, Masato Nakamura, Tatsuji Nomura, Yuan Chen, Ming Zheng, William L Fitch, Gary Peltz

Journal article  |  2013  |  Journal of Pharmacology and Experimental Therapeutics

Hepatopulmonary syndrome: Update on recent advances in pathophysiology, investigation, and treatment

Josephine A Grace, Peter W Angus

Journal article  |  2013  |  Journal of Gastroenterology and Hepatology

Advanced glycation end products augment experimental hepatic fibrosis

Michelle Goodwin, Chandana Herath, Zhiyuan Jia, Chris Leung, Melinda T Coughlan, Josephine Forbes, Peter Angus

Journal article  |  2013  |  Journal of Gastroenterology and Hepatology

Paracetamol overdose in Victoria remains a significant health-care burden

S SOOD, J HOWELL, V Sundararajan, PW Angus, PJ Gow

Journal article  |  2013  |  Journal of Gastroenterology and Hepatology

Faldaprevir (BI 201335), deleobuvir (BI 207127) and ribavirin oral therapy for treatment-naive HCV genotype 1: SOUND-C1 final results.

Stefan Zeuzem, Tarik Asselah, Peter Angus, Jean-Pierre Zarski, Dominique Larrey, Beat Müllhaupt, Ed Gane, Marcus Schuchmann, Ansgar W Lohse, Stanislas Pol, Jean-Pierre Bronowicki, Stuart Roberts, Keikawus Arasteh, Fabien Zoulim, Markus Heim, Jerry O Stern, Gerhard Nehmiz, George Kukolj, Wulf O Böcher, Federico J Mensa

Journal article  |  2013  |  Antiviral Therapy

BACKGROUND: Faldaprevir (BI 201335) and deleobuvir (BI 207127) are direct-acting antiviral agents under development for the treatm..

Angiotensin-(1-7) reduces the perfusion pressure response to angiotensin II and methoxamine via an endothelial nitric oxide-mediated pathway in cirrhotic rat liver

Chandana B Herath, Kai Mak, Louise M Burrell, Peter W Angus

Journal article  |  2013  |  American Journal of Physiology - Gastrointestinal and Liver Physiology

Global perspectives: Australia - Real world experience with HBV antiviral therapy

D Ratnam, P Angus

Journal article  |  2012  |  Current Hepatitis Reports

In reference to higher serum testosterone is associated with increased risk of advanced hepatitis c-related liver disease in males

Marie Sinclair, Mathis Grossmann, Paul Gow, Peter Angus

Journal article  |  2012  |  Hepatology

Update on new aspects of the renin-angiotensin system in liver disease: clinical implications and new therapeutic options

Josephine A Grace, Chandana B Herath, Kai Yan Mak, Louise M Burrell, Peter W Angus

Journal article  |  2012  |  Clinical Science

Low testosterone levels as an independent predictor of mortality in men with chronic liver disease

Mathis Grossmann, Rudolf Hoermann, Linsey Gani, Irene Chan, Ada Cheung, Paul J Gow, Angela Li, Jeffrey D Zajac, Peter Angus

Journal article  |  2012  |  Clinical Endocrinology

Early-onset versus late-onset nonanastomotic biliary strictures post liver transplantation: risk factors reflect different pathogenesis

Jessica A Howell, Paul J Gow, Peter W Angus, Robert M Jones, Bao-Zhong Wang, Michael Bailey, Michael A Fink

Journal article  |  2012  |  Transplant International

Enhanced apoptosis in post-liver transplant hepatitis C: Effects of virus and immunosuppressants

Eu Jin Lim, Ruth Chin, Peter W Angus, Joseph Torresi

Journal article  |  2012  |  World Journal of Gastroenterology

Effect of IL28B Genotype on Early Viral Kinetics During Interferon-Free Treatment of Patients With Chronic Hepatitis C

Tom W Chu, Rohit Kulkarni, Edward J Gane, Stuart K Roberts, Catherine Stedman, Peter W Angus, Brett Ritchie, Xiao-Yu Lu, David Ipe, Uri Lopatin, Soren Germer, Victor A Iglesias, Robert Elston, Patrick F Smith, Nancy S Shulman

Journal article  |  2012  |  Gastroenterology

Review article: the pathophysiological roles of the renin-angiotensin system in the gastrointestinal tract

M Garg, PW Angus, LM Burrell, C Herath, PR Gibson, JS Lubel

Journal article  |  2012  |  Alimentary Pharmacology and Therapeutics

Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection.

Stefan Zeuzem, Tarik Asselah, Peter Angus, Jean-Pierre Zarski, Dominique Larrey, Beat Müllhaupt, Ed Gane, Marcus Schuchmann, Ansgar Lohse, Stanislas Pol, Jean-Pierre Bronowicki, Stuart Roberts, Keikawus Arasteh, Fabien Zoulim, Markus Heim, Jerry O Stern, George Kukolj, Gerhard Nehmiz, Carla Haefner, Wulf Otto Boecher

Journal article  |  2011  |  Gastroenterology

BACKGROUND & AIMS: Therapeutic regimens are being developed for patients with hepatitis C virus (HCV) infection that do not includ..

Viral factors influencing the outcome of human cytomegalovirus infection in liver transplant recipients.

GM Scott, Z Naing, J Pavlovic, JM Iwasenko, P Angus, R Jones, WD Rawlinson

Journal article  |  2011  |  Journal of Clinical Virology

BACKGROUND: Cytomegalovirus (CMV) remains the leading viral cause of disease following orthotopic liver transplantation (OLT) desp..

Acute hepatitis B infection following blood transfusion

AP Rode, RM Jones, PW Angus, D Brown, PJ Gow

Journal article  |  2011  |  Internal Medicine Journal

Diagnosis and management of acute variceal bleeding: Asian Pacific Association for Study of the Liver recommendations

Shiv Kumar Sarin, Ashish Kumar, Peter W Angus, Sanjay Saran Baijal, Soon Koo Baik, Yusuf Bayraktar, Yogesh Kumar Chawla, Gourdas Choudhuri, Jin Wook Chung, Roberto de Franchis, H Janaka de Silva, Hitendra Garg, Pramod Kumar Garg, Ahmed Helmy, Ming-Chih Hou, Wasim Jafri, Ji-Dong Jia, George K Lau, Chang-Zheng Li, Hock Foong Lui, et al.

Journal article  |  2011  |  Hepatology International

Erratum: Hodgkin lymphoma and fulminant hepatic failure (Leukemia and Lymphoma (2010) 51:5 (947-951) DOI: 10.3109/10428191003699571)

FS Hong, CL Smith, PW Angus, P Crowley, WK Ho

Journal article  |  2011  |  Leukemia & Lymphoma

Viral factors influencing the outcome of human cytomegalovirus infection in liver transplant recipients

GM Scott, Z Naing, J Pavlovic, JM Iwasenko, P Angus, R Jones, WD Rawlinson

Journal article  |  2011  |  Journal of Clinical Virology

Acute allograft rejection in human liver transplant recipients is associated with signaling through toll-like receptor 4

Adam G Testro, Kumar Visvanathan, Narelle Skinner, Vesna Markovska, Peter Crowley, Peter W Angus, Paul J Gow

Journal article  |  2011  |  Journal of Gastroenterology and Hepatology

Post-liver transplantation multicentric Castleman disease treated with valganciclovir and weaning of immunosuppression.

EJ Lim, P Crowley, CA Mitchell, PW Angus

Journal article  |  2011  |  American Journal of Transplantation

Multicentric Castleman disease is a lymphoproliferative disorder which when seen in the setting of HIV/AIDS is often associated wi..

Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial

Edward J Gane, Stuart K Roberts, Catherine AM Stedman, Peter W Angus, Brett Ritchie, Rob Elston, David Ipe, Peter N Morcos, Linda Baher, Isabel Najera, Tom Chu, Uri Lopatin, M Michelle Berrey, William Bradford, Mark Laughlin, Nancy S Shulman, Patrick F Smith

Journal article  |  2010  |  The Lancet

Hodgkin lymphoma and fulminant hepatic failure

Frank S Hong, Carole L Smith, Peter W Angus, Peter Crowley, Wai Khoon Ho

Journal article  |  2010  |  Leukemia & Lymphoma

Efficacy and cost of a hepatocellular carcinoma screening program at an Australian teaching hospital.

Mary YY Qian, Rong Yuwei J, Peter Angus, Tony Schelleman, Lynne Johnson, Paul Gow

Journal article  |  2010  |  Journal of Gastroenterology and Hepatology

BACKGROUND AND AIM: Western countries are seeing an increasing prevalence of chronic viral hepatitis and a subsequent rise in the ..

Hepatitis B reactivation in patients receiving cytotoxic chemotherapy: Diagnosis and management

John S Lubel, Peter W Angus

Journal article  |  2010  |  Journal of Gastroenterology and Hepatology

Changes in the renin angiotensin system during the development of colorectal cancer liver metastases

Jaclyn H Neo, Eleanor I Ager, Peter W Angus, Jin Zhu, Chandana B Herath, Christopher Christophi

Journal article  |  2010  |  BMC Cancer

Effects of antibiotics on expression and function of Toll-like receptors 2 and 4 on mononuclear cells in patients with advanced cirrhosis

Adam G Testro, Paul J Gow, Peter W Angus, Sarah Wongseelashote, Narelle Skinner, Vesna Markovska, Kumar Visvanathan

Journal article  |  2010  |  Journal of Hepatology

A Case of Fulminant Hepatic Failure in Pregnancy

John Halliday, Julie Lokan, Peter W Angus, Paul Gow

Journal article  |  2010  |  Hepatology

Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat

John S Lubel, Chandana B Herath, Jorge Tchongue, Josephine Grace, Zhiyuan Jia, Karen Spencer, David Casley, Peter Crowley, William Sievert, Louise M Burrell, Peter W Angus

Journal article  |  2009  |  Clinical Science

Endoscopic Variceal Ligation for Primary Prophylaxis of Esophageal Variceal Hemorrhage in Pre-Liver Transplant Patients

Eu Jin Lim, Paul J Gow, Peter W Angus

Journal article  |  2009  |  Liver Transplantation

Targeting circulatory dysfunction in cirrhosis: Terlipressin and the hepatorenal syndrome

Adam G Testro, Peter W Angus

Journal article  |  2009  |  Journal of Gastroenterology and Hepatology

Urotensin II modulates hepatic fibrosis and portal hemodynamic alterations in rats

William Kemp, Andrew Kompa, Arintaya Phrommintikul, Chandana Herath, Zhiyuan Jia, Peter Angus, Catriona McLean, Stuart Roberts, Henry Krum

Journal article  |  2009  |  American Journal of Physiology - Gastrointestinal and Liver Physiology

Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2

Chandana B Herath, John S Lubel, Zhiyuan Jia, Elena Velkoska, David Casley, Lindsay Brown, Chris Tikellis, Louise M Burrell, Peter W Angus

Journal article  |  2009  |  American Journal of Physiology - Gastrointestinal and Liver Physiology

Post-liver transplant hepatitis B prophylaxis: the role of oral nucleos(t)ide analogues

Scott J Patterson, Peter W Angus

Journal article  |  2009  |  Current Opinion in Organ Transplantation

Intrahepatic cholestasis of pregnancy: When should you look further?

Winita Hardikar, Shivani Kansal, Ronald PJ Oude Elferink, Peter Angus

Journal article  |  2009  |  World Journal of Gastroenterology

Donor Mannose-Binding Lectin Deficiency Increases the Likelihood of Clinically Significant Infection after Liver Transplantation

Daniel L Worthley, Douglas F Johnson, Damon P Eisen, Melinda M Dean, Susan L Heatley, John-Paul Tung, Justin Scott, Robert TA Padbury, Hugh A Harley, Peter G Bardy, Peter W Angus, Charles G Mullighan

Journal article  |  2009  |  Clinical Infectious Diseases

Editorial: Targeting circulatory dysfunction in cirrhosis: Terlipressin and the hepatorenal syndrome

AG Testro, PW Angus

Journal article  |  2009  |  Journal of Gastroenterology and Hepatology (Australia)

Angiotensin converting enzyme 2 (ACE2) activity in fetal calf serum: implications for cell culture research

JS Lubel, CB Herath, E Velkoska, DJ Casley, LM Burrell, PW Angus

Journal article  |  2008  |  Cytotechnology

A Randomized Study of Adefovir Dipivoxil in Place of HBIG in Combination with Lamivudine As Post-Liver Transplantation Hepatitis B Prophylaxis

Peter W Angus, Scott J Patterson, Simone J Strasser, Geoffrey W McCaughan, Edward Gane

Journal article  |  2008  |  Hepatology

Long-term outcome of patients treated with terlipressin for types 1 and 2 hepatorenal syndrome

Adam G Testro, Sarah Wongseelashote, Peter W Angus, Paul J Gow

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology

Liver transplantation for hepatitis B: What is the best hepatitis B immune globulin/antiviral regimen?

Peter W Angus, Scott J Patterson

Journal article  |  2008  |  Liver Transplantation

Primary prophylaxis of gastroesophageal variceal bleeding: Consensus recommendations of the Asian Pacific Association for the Study of the Liver

SK Sarin, A Kumar, PW Angus, SS Baijal, YK Chawla, RK Dhiman, H Janaka de Silva, S Hamid, S Hirota, MC Hou, W Jafri, M Khan, LA Lesmana, HF Lui, V Malhotra, H Maruyama, DG Mazumder, M Omata, U Poddar, AS Puri, et al.

Journal article  |  2008  |  Hepatology International

Defective hepatitis B virus DNA is not associated with disease status but is reduced by polymerase mutations associated with drug resistance

Scott Preiss, Margaret Littlejohn, Peter Angus, Alex Thompson, Paul Desmond, Sharon R Lewin, Joe Sasadeusz, Gail Matthews, Gregory J Dore, Tim Shaw, Vitini Sozzi, Lilly Yuen, George Lau, Anna Ayres, Chloe Thio, Anchalee Avihingsanon, Kiat Ruxrungtham, Stephen Locarnini, Peter A Revill

Journal article  |  2008  |  Hepatology

Liver disease and the renin-angiotensin system: Recent discoveries and clinical implications

John S Lubel, Chandana B Herath, Louise M Burrell, Peter W Angus

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology

Liver disease and the renin-angiotensin system: Recent discoveries and clinical implications

John S Lubel, Chandana B Herath, Louise M Burrell, Peter W Angus

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology (Australia)

Reply

JS Lubel, PW Angus

Journal article  |  2008  |  Internal Medicine Journal

The Effect of Liver Disease on the Gastrointestinal Tract

RW Chapman, PW Angus

Book Chapter  |  2008

The Effect of Gastrointestinal Diseases on the Liver and Biliary Tract

RW Chapman, PW Angus

Book Chapter  |  2008

Acid-base balance in combined severe hepatic and renal failure: A quantitative analysis

T Naka, R Bellomo, H Morimatsu, J Rocktaschel, L Wan, P Gow, P Angus

Journal article  |  2008  |  International Journal of Artificial Organs

Norfloxacin and trimethoprim-sulfamethoxazole therapy have similar efficacy in prevention of spontaneous bacterial peritonitis

Steve Lontos, Paul J Gow, Rhys B Vaughan, Peter W Angus

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology

Time to review the selection criteria for transplantation in paracetamol-induced fulminant hepatic failure?

Paul J Gow

Journal article  |  2007  |  Liver Transplantation

Hepatitis B virus reactivation following immunosuppressive therapy: guidelines for prevention and management.

JS Lubel, AG Testro, PW Angus

Journal article  |  2007  |  Internal Medicine Journal

It is well known that immunosuppressive drugs or cancer chemotherapy can stimulate replication of hepatitis B virus (HBV) and prec..

Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1-7) levels in experimental biliary fibrosis

Chandana B Herath, Fiona J Warner, John S Lubel, Rachael G Dean, Zhiyuan Jia, Rebecca A Lew, A Ian Smith, Louise M Burrell, Peter W Angus

Journal article  |  2007  |  Hepatology

Effect of sustained viral response on hepatic venous pressure gradient in hepatitis C-related cirrhosis

Stuart Roberts, Adam Gordon, Catriona McLean, John Pedersen, Scott Bowden, Kenneth Thomson, Peter Angus

Journal article  |  2007  |  Clinical Gastroenterology and Hepatology

Liver fibrosis: a balance of ACEs?

Fiona J Warner, John S Lubel, Geoffrey W Mccaughan, Peter W Angus

Journal article  |  2007  |  Clinical Science

Hereditary amyloidosis with progressive peripheral neuropathy associated with apolipoprotein Al Gly26Arg: Outcome of hepatorenal transplantation

Adam G Testro, Stephen O Brennan, Richard AL Macdonell, Philip N Hawkins, Peter W Angus

Journal article  |  2007  |  Liver Transplantation

Accidental paracetamol poisoning

John S Lubel, Peter W Angus, Paul J Gow

Journal article  |  2007  |  Medical Journal of Australia

Lamivudine plus low-dose hepatitis B immunoglobulin to prevent recurrent hepatitis B following liver transplantation

Edward J Gane, Peter W Angus, Simone Strasser, Darrell HG Crawford, John Ring, Gary P Jeffrey, Geoffrey W McCaughan

Journal article  |  2007  |  Gastroenterology

Adefovir dipivoxil for wait-listed and post-liver transplantation patients with lamivudine-resistant hepatitis B: final long-term results.

Eugene Schiff, Ching-Lung Lai, Stephanos Hadziyannis, Peter Neuhaus, Norah Terrault, Massimo Colombo, Hans Tillmann, Didier Samuel, Stefan Zeuzem, Jean-Pierre Villeneuve, Sarah Arterburn, Katyna Borroto-Esoda, Carol Brosgart, Steven Chuck, undefined Adefovir Dipivoxil Study 45 Intrnational Investigators Group

Journal article  |  2007  |  Liver Transplantation

Wait-listed (n = 226) or post-liver transplantation (n = 241) chronic hepatitis B (CHB) patients with lamivudine-resistant hepatit..

Erratum: Risk factors for liver transplantation waiting list mortality (Journal of Gastroenterology (DOI: 10.1111/j.1440-1746.2006.04422.x))

MA Fink, SR Berry, PJ Gow, PW Angus, BZ Wang, V Muralidharan, C Christophi, RM Jones

Journal article  |  2007  |  Journal of Gastroenterology and Hepatology

Hepatitis B and C virus infections and anti-tumor necrosis factor-alpha therapy: Guidelines for clinical approach

Debbie M Nathan, Peter W Angus, Peter R Gibson

Journal article  |  2006  |  Journal of Gastroenterology and Hepatology

Role of endothelin in systemic and portal resistance in cirrhosis.

PW Angus

Journal article  |  2006  |  Gut

Acid-base balance during continuous veno-venous hemofiltration: The impact of severe hepatic failure

T Naka, R Bellomo, H Morimatsu, J Rocktaschel, L Wan, P Gow, P Angus

Journal article  |  2006  |  The International Journal of Artificial Organs

Zoledronic acid prevents bone loss after liver transplantation: a randomized, double-blind, placebo-controlled trial.

Bronwyn AL Crawford, Cherie Kam, Julie Pavlovic, Karen Byth, David J Handelsman, Peter W Angus, Geoffrey W McCaughan

Journal article  |  2006  |  Annals of Internal Medicine

BACKGROUND: Clinically important rapid bone loss occurs within 3 to 6 months after liver transplantation and may be associated wit..

Role of the endothelium on vasoactive agents in patients with liver cirrhosis

S Battaglia, P Angus, JPF Chin-Dusting

Journal article  |  2006  |  Journal of Gastroenterology and Hepatology

Acid base balance during continuous veno-venous hemofiltration: the impact of severe hepatic failure

undefined naka, R BELLOMO, undefined Morimatsu, undefined Rocktaschel, undefined wan, undefined gow, P ANGUS

Journal article  |  2006  |  International Journal of Artificial Organs

Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2

G Paizis, C Tikellis, ME Cooper, JM Schembri, RA Lew, AI Smith, T Shaw, FJ Warner, A Zuilli, LM Burrell, PW Angus

Journal article  |  2005  |  Gut

Mannose-binding lectin and liver transplantation.

Daniel L Worthley, Peter G Bardy, Peter Angus, Hugh Harley, Charles G Mullighan

Journal article  |  2005  |  Gastroenterology

Vasoconstrictor responses are normal but prostanoid-mediated vasodilatation is enhanced in human cirrhotic mesenteric arteries

RB Vaughan, JA Angus, PW Angus

Journal article  |  2005  |  Journal of Gastroenterology and Hepatology

Liver transplant recipient selection: MELD vs. clinical judgment

MA Fink, PW Angus, PJ Gow, SR Berry, BZ Wang, V Muralidharan, C Christophi, RM Jones

Journal article  |  2005  |  Liver Transplantation

Flucloxacillin-induced aplastic anaemia and liver failure

JL Dobson, PW Angus, R Jones, P Crowley, PJ Gow

Journal article  |  2005  |  Transplant International

Modern management of portal hypertension.

JS Lubel, PW Angus

Journal article  |  2005  |  Internal Medicine Journal

The development of portal hypertension plays a major role in the pathogenesis of many of the complications of chronic liver diseas..

Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to Lamivudine.

DJ Tenney, SM Levine, RE Rose, AW Walsh, SP Weinheimer, L Discotto, M Plym, K Pokornowski, CF Yu, P Angus, A Ayres, A Bartholomeusz, W Sievert, G Thompson, N Warner, S Locarnini, RJ Colonno

Journal article  |  2004  |  Antimicrobial Agents and Chemotherapy

Entecavir (ETV) exhibits potent antiviral activity in patients chronically infected with wild-type or lamivudine (3TC)-resistant (..

Hepatic failure due to fibrosing cholestatic hepatitis in a patient with pre-surface mutant hepatitis B virus and mixed connective tissue disease treated with prednisolone and chloroquine

SA Zanati, SA Locarnini, JP Dowling, PW Angus, FJ Dudley, SK Roberts

Journal article  |  2004  |  Journal of Clinical Virology

Epidemiology of primary biliary cirrhosis in Victoria, Australia: high prevalence in migrant populations.

Siddharth Sood, Paul J Gow, John M Christie, Peter W Angus

Journal article  |  2004  |  Gastroenterology

BACKGROUND & AIMS: The prevalence of primary biliary cirrhosis (PBC) reported in different countries varies widely, indicating tha..

Patient and graft survival after liver transplantation for hereditary hemochromatosis: Implications for pathogenesis.

Darrell HG Crawford, Linda M Fletcher, Stefan G Hubscher, Katherine A Stuart, Edward Gane, Peter W Angus, Gary P Jeffrey, Geoffrey W McCaughan, Paul Kerlin, Lawrie W Powell, Elwyn E Elias

Journal article  |  2004  |  Hepatology

The clinical outcome of patients who have undergone liver transplantation for hereditary hemochromatosis (HH) or who have received..

Responses to endothelin-1 in patients with advanced cirrhosis before and after liver transplantation.

PW Angus, RB Vaughan, JPF Chin-Dusting

Journal article  |  2004  |  Gut

Lamivudine-resistant hepatitis B virus and ongoing lamivudine therapy: stop the merry-go-round, it's time to get off!

Peter Angus, Stephen Locarnini

Journal article  |  2004  |  Antiviral Therapy

Fatal fulminant hepatic failure induced by a natural therapy containing kava.

Michael Thomsen, Luis Vitetta, Matthias Schmidt, Avni Sali

Journal article  |  2004  |  Medical Journal of Australia

Management of healthcare workers after occupational exposure to hepatitis C virus.

Nicola Magnavita

Journal article  |  2004  |  Medical Journal of Australia

Successful stenting for Budd-Chiari syndrome after pediatric liver transplantation: a case series and review of the literature

S Rerksuppaphol, W Hardikar, AL Smith, JL Wilkinson, TH Goh, P Angus, R Jones

Journal article  |  2004  |  Pediatric Surgery International

Etiology and outcome of fulminant hepatic failure managed at an Australian liver transplant unit

PJ Gow, RM Jones, JL Dobson, PW Angus

Journal article  |  2004  |  Journal of Gastroenterology and Hepatology

Erratum: Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver (Gastroenterology (2002) 123 (1667-1676))

G Paizis, ME Cooper, JM Schembri, C Tikellis, LM Burrell, PW Angus

Journal article  |  2004  |  Gastroenterology

Acute liver failure associated with the use of herbal preparations containing black cohosh

S Lontos, RM Jones, PW Angus, PJ Gow

Journal article  |  2003  |  Medical Journal of Australia

Evidence for altered vascular responses to exogenous endothelin-1 in patients with advanced cirrhosis with restoration of the normal vasoconstrictor response following successful liver transplantation.

RB Vaughan, PW Angus, JPF Chin-Dusting

Journal article  |  2003  |  Gut

BACKGROUND AND AIMS: There is evidence that dampened responses to endogenous vasoconstrictors contribute to the hyperdynamic circu..

Management of healthcare workers after occupational exposure to hepatitis C virus

PGP Charles, PW Angus, JJ Sasadeusz, ML Grayson

Journal article  |  2003  |  Medical Journal of Australia

Cryoprecipitate for the correction of coagulopathy associated with liver disease

CJ French, R Bellomo, P Angus

Journal article  |  2003  |  Anaesthesia and Intensive Care

Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase.

Peter Angus, Rhys Vaughan, Shelly Xiong, Huiling Yang, William Delaney, Craig Gibbs, Carol Brosgart, Danielle Colledge, Rosalind Edwards, Anna Ayres, Angeline Bartholomeusz, Stephen Locarnini

Journal article  |  2003  |  Gastroenterology

BACKGROUND & AIMS: Adefovir dipivoxil effectively inhibits both hepatitis B virus (HBV) replication and disease activity in patien..

Fatal fulminant hepatic failure induced by a natural therapy containing kava.

Paul J Gow, Nathan J Connelly, Richard L Hill, Peter Crowley, Peter W Angus

Journal article  |  2003  |  Medical Journal of Australia

We describe a case of acute liver failure and death associated with the use of a preparation containing the "natural" anxiolytic k..

Liver transplantation for HCV-associated liver cirrhosis: predictors of outcomes in a population with significant genotype 3 and 4 distribution.

A Zekry, P Whiting, DH Crawford, PW Angus, GP Jeffrey, RT Padbury, EJ Gane, GW McCaughan, undefined Australian and New Zealand Liver Transplant Clinical Study Group

Journal article  |  2003  |  Liver Transplantation

End-stage liver disease associated with hepatitis C virus (HCV) infection is now the leading indication for liver transplantation ..

The incidence, pathogenesis and natural history of steatorrhoea after bone marrow transplantation

AP Grigg, PW Angus, R Hoyt, J Szer

Journal article  |  2003  |  Bone Marrow Transplantation

Serum phosphate as a predictor of outcome in acetaminophen-induced fulminant hepatic failure.

Paul J Gow, Siddharth Sood, Peter W Angus

Journal article  |  2003  |  Hepatology

A novel method for determining hepatic sinusoidal oxygen permeability in the isolated perfused rat liver using [O-15]O-2

PR Froomes, J Sachinidis, H Ghabrial, H Tochon-Danguy, A Scott, MS Ching, DJ Morgan, PW Angus

Journal article  |  2003  |  Nuclear Medicine and Biology

Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver

G Paizis, ME Cooper, JM Schembri, C Tikellis, LM Burrell, PW Angus

Journal article  |  2002  |  Gastroenterology

Paediatric liver transplantion in Melbourne: the first 50 patients

W Hardikar, AL Smith, P Angus, A Gleeson, G Wilson, RML Jones

Journal article  |  2002  |  Pediatric Surgery International

Choledochal cyst and squamous-cell carcinoma of the biliary tract.

M Harris, P Angus, ID Davis

Journal article  |  2002  |  Internal Medicine Journal

Liver failure complicating non-alcoholic steatohepatitis following allogeneic bone marrow transplantation for Shwachman-Diamond syndrome

DS Ritchie, PW Angus, PS Bhathal, AP Grigg

Journal article  |  2002  |  Bone Marrow Transplantation

Disease recurrence after liver transplantation: Need we worry?

PJ Gow, PW Angus

Journal article  |  2002  |  Journal of Gastroenterology and Hepatology

Hepatitis B: Weighing the costs of treatment

PW Angus

Journal article  |  2002  |  Journal of Gastroenterology and Hepatology

The effect of oxygen supplementation on the arterial ketone body ratio in human cirrhosis

PR Froomes, H Ghabrial, DJ Morgan, PW Angus

Journal article  |  2002  |  Digestion

Diagnosis of Wilson's disease: an experience over three decades.

GJ Brewer

Journal article  |  2002  |  Gut

Hepatocellular carcinoma and chemoembolization.

M Harris, P Gibbs, J Cebon, R Jones, R Sewell, T Schelleman, P Angus

Journal article  |  2001  |  Internal Medicine Journal

BACKGROUND: Chemoembolization is often used in the treatment of hepatocellular carcinoma; however, there are limited data on its e..

Differential inhibition of human CYP1A1 and CYP1A2 by quinidine and quinine

MS Ching, CL Blake, NA Malek, PW Angus, H Ghabrial

Journal article  |  2001  |  Xenobiotica

Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis

G Paizis, RE Gilbert, ME Cooper, P Murthi, JM Schembri, LL Wu, JR Rumble, DJ Kelly, C Tikellis, A Cox, RA Smallwood, PW Angus

Journal article  |  2001  |  Journal of Hepatology

Duck hepatitis B virus replication in primary bile duct epithelial cells

JY Lee, JG Culvenor, P Angus, R Smallwood, A Nicoll, S Locarnini

Journal article  |  2001  |  Journal of Virology

Right heart failure impairs hepatic elimination of p-nitrophenol without inducing changes in content or latency of hepatic UDP-glucuronosyltransferases

CY Ng, H Ghabrial, DJ Morgan, MS Ching, RA Smallwood, PW Angus

Journal article  |  2000  |  Journal of Pharmacology and Experimental Therapeutics

Impaired elimination of propranolol due to right heart failure: Drug clearance in the isolated liver and its relationship to intrinsic metabolic capacity

CY Ng, H Ghabrial, DJ Morgan, MS Ching, RA Smallwood, PW Angus

Journal article  |  2000  |  Drug Metabolism and Disposition

Combination low-dose hepatitis B immune globulin and lamivudine therapy provides effective prophylaxis against posttransplantation hepatitis B.

PW Angus, GW McCaughan, EJ Gane, DH Crawford, H Harley

Journal article  |  2000  |  Liver Transplantation

Although antiviral prophylaxis with lamivudine monotherapy appears to reduce post-liver transplantation recurrence of hepatitis B ..

Diagnosis of Wilson's disease: an experience over three decades.

PJ Gow, RA Smallwood, PW Angus, AL Smith, AJ Wall, RB Sewell

Journal article  |  2000  |  Gut

BACKGROUND: Wilson's disease is a rare but treatable condition that often presents diagnostic dilemmas. These dilemmas have for th..

Effect of nucleoside analogue therapy on duck hepatitis B viral replication in hepatocytes and bile duct epithelial cells in vivo

A Nicoll, S Locarnini, ST Chou, R Smallwood, P Angus

Journal article  |  2000  |  Journal of Gastroenterology and Hepatology

Lamivudine therapy in patients undergoing liver transplantation for hepatitis B virus precore mutant-associated infection: high resistance rates in treatment of recurrence but universal prevention if used as prophylaxis with very low dose hepatitis B immune globulin.

GW McCaughan, J Spencer, D Koorey, S Bowden, A Bartholomeusz, M Littlejohn, D Verran, AK Chui, AG Sheil, RM Jones, SA Locarnini, PW Angus

Journal article  |  1999  |  Liver Transplantation and Surgery

Recurrent hepatitis B virus (HBV) infection remains a major cause of morbidity and mortality after liver transplantation. Recently..

Hepatic oxygen supplementation as therapy in cirrhotic liver disease.

PJ Harvey, D LeCouteur, AJ McLean

Journal article  |  1999  |  Gastroenterology

Bone loss at the proximal femur and reduced lean mass following liver transplantation: A longitudinal study

JB Keogh, C Tsalamandris, RB Sewell, RM Jones, PW Angus, IB Nyulasi, E Seeman

Journal article  |  1999  |  Nutrition

Comparative effects of oxygen supplementation on theophylline and acetaminophen clearance in human cirrhosis

PRA Froomes, DJ Morgan, RA Smallwood, PW Angus

Journal article  |  1999  |  Gastroenterology

Effect of cirrhosis on sulphation by the isolated perfused rat liver.

EF Choo, PW Angus, DJ Morgan

Journal article  |  1999  |  Journal of Hepatology

BACKGROUND/AIMS: There is evidence to suggest that not all pathways of drug metabolism are similarly affected in cirrhosis. The ef..

Paracetamol overdose in a liver transplantation centre: An 8-year experience

PJ Gow, RA Smallwood, PW Angus

Journal article  |  1999  |  Journal of Gastroenterology and Hepatology

Inhibition of duck hepatitis B virus replication by 9-(2-phosphonylmethoxyethyl)adenine, an acyclic phosphonate nucleoside analogue.

AJ Nicoll, DL Colledge, JJ Toole, PW Angus, RA Smallwood, SA Locarnini

Journal article  |  1998  |  Antimicrobial Agents and Chemotherapy

The use of regimens that use nucleoside analogues for the treatment of chronic hepatitis B virus infection is often limited becaus..

Successful resolution of severe graft versus host disease after liver transplantation correlating with disappearance of donor DNA from the peripheral blood

G Paizis, BD Tait, P Kyle, PW Angus, AP Grigg

Journal article  |  1998  |  Australian and New Zealand Journal of Medicine

Relationships among liver and kidney volumes, lean body mass and drug clearance

S Nawaratne, JE Brien, E Seeman, R Fabiny, J Zalcberg, W Cosolo, P Angus, DJ Morgan

Journal article  |  1998  |  British Journal of Clinical Pharmacology

Should we be screening blood donors for hepatitis G virus? The case against screening.

PY Wong, PJ Coghlan, PW Angus

Journal article  |  1998  |  Medical Journal of Australia

Hepatitis G virus and fulminant hepatic failure: evidence for transfusion-related infection.

LD Moaven, SA Locarnini, DS Bowden, JP Kim, A Breschkin, R McCaw, A Yun, J Wages, B Jones, P Angus

Journal article  |  1997  |  Journal of Hepatology

BACKGROUND/AIMS: In the majority of cases of fulminant "viral" hepatitis in Australia, no known aetiological agent can be isolated..

Resolution of gas exchange abnormalities and intrapulmonary shunting following liver transplantation.

SE Battaglia, JJ Pretto, LB Irving, RM Jones, PW Angus

Journal article  |  1997  |  Hepatology

This prospective study evaluated pulmonary gas exchange in patients with severe liver disease, its relationship to intrapulmonary ..

Budd-Chiari syndrome: intractable ascites managed by a trans-hepatic portacaval shunt.

A Nicoll, G Fitt, P Angus, R Sewell, O Hennessy

Journal article  |  1997  |  Australasian Radiology

Transjugular intrahepatic portosystemic shunts (TIPS) have recently been used to manage the portal hypertensive complications of t..

Hepatitis B virus polymerase mutations during antiviral therapy in a patient following liver transplantation.

TT Aye, A Bartholomeusz, T Shaw, S Bowden, A Breschkin, J McMillan, P Angus, S Locarnini

Journal article  |  1997  |  Journal of Hepatology

BACKGROUND/AIMS: The purpose of this study was to investigate possible resistance mutations which arose in the polymerase gene of ..

Transplantation in patients with paracetamol-induced fulminant hepatic failure.

PJ Gow, PW Angus, RA Smallwood

Journal article  |  1997  |  The Lancet

Demonstration of duck hepatitis B virus in bile duct epithelial cells: implications for pathogenesis and persistent infection.

AJ Nicoll, PW Angus, ST Chou, CA Luscombe, RA Smallwood, SA Locarnini

Journal article  |  1997  |  Hepatology

Hepatitis B virus (HBV) has been demonstrated in bile duct epithelial cells (BDEC) during chronic infection. The persistence of vi..

Review: Hepatitis B and liver transplantation

PW Angus

Journal article  |  1997  |  Journal of Gastroenterology and Hepatology

Effects of acute myocardial infarction on theophylline elimination in rats

CY Ng, H Ghabrial, DJ Morgan, RA Smallwood, PW Angus

Journal article  |  1997  |  Drug Metabolism and Disposition

Mutations in the hepatitis B virus precore/core gene and core promoter in patients with severe recurrent disease following liver transplantation.

JS McMillan, DS Bowden, PW Angus, GW McCaughan, SA Locarnini

Journal article  |  1996  |  Hepatology

Recurrent hepatitis B virus (HBV) infection is a major problem in patients undergoing liver transplantation. Previously, we report..

Retransplantation for precore mutant-related chronic hepatitis B infection: prolonged survival in a patient receiving sequential ganciclovir/famciclovir therapy.

G McCaughan, P Angus, S Bowden, T Shaw, A Breschkin, R Sheil, S Locarnini

Journal article  |  1996  |  Liver Transplantation and Surgery

Retransplantation for hepatitis B-related liver allograft failure is rarely successful. Recurrence of infection is almost universa..

Liver transplantation in Australia: a decade on.

PW Angus, RA Smallwood, RM Jones

Journal article  |  1996  |  The Medical journal of Australia

Increased sensitivity of propranolol clearance to reduced oxygen delivery in the isolated perfused cirrhotic rat liver.

PL Hickey, AJ McLean, PW Angus, EF Choo, DJ Morgan

Journal article  |  1996  |  Gastroenterology

BACKGROUND & AIMS: Capillarization of the sinusoids in cirrhosis is proposed to reduce oxygen availability to the hepatocyte, resu..

Liver transplantation in metastatic carcinoid tumour

ML Coperchini, R Jones, P Angus, A Read, G Schmidt, J Zalcberg

Journal article  |  1996  |  Australian and New Zealand Journal of Medicine

Effect of immunosuppressive and antiviral agents on hepatitis B virus replication in vitro.

JS McMillan, T Shaw, PW Angus, SA Locarnini

Journal article  |  1995  |  Hepatology

Hepatitis B virus (HBV) DNA-transfected hepatoma cells were incubated with the immunosuppressive agents prednisolone, azathioprine..

Low prevalence of primary biliary cirrhosis in Victoria, Australia. Melbourne Liver Group.

RG Watson, PW Angus, M Dewar, B Goss, RB Sewell, RA Smallwood

Journal article  |  1995  |  Gut

A prevalence study of primary biliary cirrhosis was carried out in the state of Victoria, Australia, by means of a mail survey of ..

RIGHT HEART-FAILURE IMPAIRS HEPATIC OXYGENATION AND THEOPHYLLINE CLEARANCE IN RATS

CY NG, PW ANGUS, H GHABRIAL, ST CHOU, L ARNOLDA, DJ MORGAN, RA SMALLWOOD

Journal article  |  1995  |  Journal of Pharmacology and Experimental Therapeutics

Oxygen supplementation restores theophylline clearance to normal in cirrhotic rats.

PL Hickey, PW Angus, AJ McLean, DJ Morgan

Journal article  |  1995  |  Gastroenterology

BACKGROUND/AIMS: Capillarization associated with hepatic fibrosis may present a functional barrier to oxygen diffusion into the he..

Effects of chronic left ventricular failure on hepatic oxygenation and theophylline elimination in the rat.

PW Angus, CY Ng, H Ghabrial, DJ Morgan, RA Smallwood

Journal article  |  1995  |  Drug Metabolism and Disposition

The effect of heart failure on the hepatic elimination of low-clearance drugs has not been clearly defined. We investigated the ef..

HEPATITIS-B VIRUS PRECORE MUTANT INFECTION IS ASSOCIATED WITH SEVERE RECURRENT DISEASE AFTER LIVER-TRANSPLANTATION

PW ANGUS, SA LOCARNINI, GW MCCAUGHAN, RM JONES, JS MCMILLAN, DS BOWDEN

Journal article  |  1995  |  Hepatology

PATTERNS OF COAGULOPATHY DURING LIVER-TRANSPLANTATION - EXPERIENCE WITH THE FIRST 75 CASES USING THROMBELASTOGRAPHY

PL MCNICOL, G LIU, ID HARLEY, PR MCCALL, GM PRZYBYLOWSKI, J BOWKETT, PW ANGUS, KJ HARDY, RM JONES

Journal article  |  1994  |  Anaesthesia and Intensive Care

BLOOD-LOSS AND TRANSFUSION REQUIREMENTS IN LIVER-TRANSPLANTATION - EXPERIENCE WITH THE FIRST 75 CASES

PL MCNICOL, G LIU, ID HARLEY, PR MCCALL, GM PRZYBYLOWSKI, J BOWKETT, PW ANGUS, KJ HARDY, RM JONES

Journal article  |  1994  |  Anaesthesia and Intensive Care

LYMPHOPROLIFERATIVE DISEASE OF DONOR ORIGIN ARISING IN PATIENTS AFTER ORTHOTOPIC LIVER-TRANSPLANTATION

JE ARMES, P ANGUS, MC SOUTHEY, SE BATTAGLIA, BC ROSS, RM JONES, DJ VENTER

Journal article  |  1994  |  Cancer

Transjugular intrahepatic portal-systemic shunts (TIPS)--initial experience and clinical outcome.

GS Hebbard, G Fitt, KR Thomson, PW Angus, R Jones, RB Sewell, PR Gibson, O Hennessy

Journal article  |  1994  |  Australian and New Zealand Journal of Medicine

BACKGROUND: The clinical role of the transjugular intrahepatic portal-systemic shunt (TIPS) has not been fully defined. AIMS: To d..

Hepatopulmonary syndrome--response to liver transplantation--new insights into an old problem.

L Irving, PW Angus, JJ Pretto, RJ Pierce

Journal article  |  1993  |  Australian and New Zealand Journal of Medicine

BENEFICIAL EFFECT OF PROSTAGLANDIN-E(1) ON HEPATIC ALLOGRAFT-REJECTION FOLLOWING ORTHOTOPIC LIVER-TRANSPLANTATION

S TANCHAROEN, RM JONES, PW ANGUS, KJ HARDY

Journal article  |  1993  |  Transplantation Proceedings

HIGH-DOSE ORAL ACYCLOVIR REDUCES THE INCIDENCE OF CYTOMEGALOVIRUS-INFECTION IN LIVER-TRANSPLANT RECIPIENTS

LC MOLLISON, MJ RICHARDS, PDR JOHNSON, K HAYES, WJ MUNCKHOF, RM JONES, PD DABKOWSKI, PW ANGUS

Journal article  |  1993  |  Journal of Infectious Diseases

Can we afford to transplant?

CA Martin

Journal article  |  1993  |  Medical Journal of Australia

Combination antiviral therapy controls severe post-liver transplant recurrence of hepatitis B virus infection.

P Angus, M Richards, S Bowden, J Ireton, R Sinclair, R Jones, S Locarnini

Journal article  |  1993  |  Journal of Gastroenterology and Hepatology

The authors have successfully used combination ganciclovir and foscarnet chemotherapy to control viral replication following liver..

SITE OF PRINCIPAL METABOLIC DEFECT IN IDIOPATHIC HEMOCHROMATOSIS - INSIGHTS FROM TRANSPLANTATION OF AN AFFECTED ORGAN

PL DABKOWSKI, PW ANGUS, RA SMALLWOOD, J IRETON, RM JONES

Journal article  |  1993  |  BMJ

THE EFFECT OF HYPOXIA AND ACIDOSIS ON PROPRANOLOL CLEARANCE IN THE ISOLATED PERFUSED-RAT-LIVER PREPARATION

SL ELLIOTT, DJ MORGAN, PW ANGUS, H GHABRIAL, RA SMALLWOOD

Journal article  |  1993  |  Biochemical Pharmacology

THE EFFECT OF HYPOXIA ON PROPRANOLOL CLEARANCE DURING ANTEGRADE AND RETROGRADE FLOW IN THE ISOLATED PERFUSED-RAT-LIVER PREPARATION

SL ELLIOTT, DJ MORGAN, PW ANGUS, H GHABRIAL, RGP WATSON, RA SMALLWOOD

Journal article  |  1993  |  Biochemical Pharmacology

Can we afford to transplant?

SV Mitchell, RA Smallwood, PW Angus, HM Lapsley

Journal article  |  1993  |  Medical Journal of Australia

SENSITIVITY OF PROPRANOLOL ELIMINATION TO HYPOXIA IN THE ISOLATED PERFUSED-RAT-LIVER PREPARATION

SL ELLIOTT, DJ MORGAN, PW ANGUS, H GHABRIAL, RA SMALLWOOD

Journal article  |  1993  |  Clinical and Experimental Pharmacology and Physiology

Cure of Rhizopus sinusitis in a liver transplant recipient with liposomal amphotericin B.

W Munckhof, R Jones, FA Tosolini, A Marzec, P Angus, ML Grayson

Journal article  |  1993  |  Clinical Infectious Diseases

31P magnetic resonance spectroscopy detects a functional abnormality in liver metabolism after acetaminophen poisoning.

RM Dixon, PW Angus, B Rajagopalan, GK Radda

Journal article  |  1992  |  Hepatology

Eighteen patients with acetaminophen poisoning were studied with 31P magnetic resonance spectroscopy to measure phosphorus-contain..

PROSTAGLANDIN-E1 THERAPY IN ORTHOTOPIC LIVER-TRANSPLANTATION RECIPIENTS - INDICATIONS AND OUTCOME

S TANCHAROEN, RM JONES, PW ANGUS, ID MICHELL, L MCNICOL, KJ HARDY

Journal article  |  1992  |  Transplantation Proceedings

PSYCHOSOCIAL ADJUSTMENT TO ILLNESS - QUALITY-OF-LIFE FOLLOWING LIVER-TRANSPLANTATION

KA MOORE, RM JONES, P ANGUS, K HARDY, G BURROWS

Journal article  |  1992  |  Transplantation Proceedings

A study of galactose intolerance in human and rat liver in vivo by 31P magnetic resonance spectroscopy.

B Kalderon, RM Dixon, B Rajagopalan, PW Angus, RD Oberhaensli, JE Collins, JV Leonard, GK Radda

Journal article  |  1992  |  Pediatric Research

An oral load of 20 mg/kg galactose produces significant changes in the 31P magnetic resonance spectrum of the liver of a galactose..

Oral fluticasone propionate in active distal ulcerative colitis.

P Angus, JA Snook, M Reid, DP Jewell

Journal article  |  1992  |  Gut

Fluticasone propionate is a new corticosteroid with low systemic bioavailability. This study reports the outcome of a double blind..

HEPATITIS DUE TO NITROFURANTOIN

LC MOLLISON, P ANGUS, M RICHARDS, RM JONES, J IRETON

Journal article  |  1992  |  Medical Journal of Australia

LIVER-TRANSPLANTATION IN VICTORIA

PW ANGUS, RM JONES, KJ HARDY, PL MCNICOL, DR FLETCHER, RB SEWELL, RA SMALLWOOD, A SMITH, I MICHELL, P JOHNSON, L MOLLISON, P DABKOWSKI, A GLEESON

Journal article  |  1992  |  Transplantation Proceedings

PROSTAGLANDIN-E1 FOR THE TREATMENT OF PRIMARY NON-FUNCTION OF THE DONOR ORGAN IN LIVER-TRANSPLANTATION

LC MOLLISON, PW ANGUS, RM JONES

Journal article  |  1991  |  Medical Journal of Australia

Abnormal phosphomonoester signals in 31P MR spectra from patients with hepatic lymphoma. A possible marker of liver infiltration and response to chemotherapy.

RM Dixon, PW Angus, B Rajagopalan, GK Radda

Journal article  |  1991  |  British Journal of Cancer

Hepatic infiltration by lymphoma can be difficult to detect by conventional methods. We have studied 22 patients in vivo 31P magne..

ORAL BIOAVAILABILITY OF OMEPRAZOLE BEFORE AND AFTER CHRONIC THERAPY IN PATIENTS WITH DUODENAL-ULCER

MS CHING, GW MIHALY, PW ANGUS, DJ MORGAN, S DEVENISHMEARES, ND YEOMANS, RA SMALLWOOD

Journal article  |  1991  |  British Journal of Clinical Pharmacology

Fructose-induced aberration of metabolism in familial gout identified by 31P magnetic resonance spectroscopy.

JE Seegmiller, RM Dixon, GJ Kemp, PW Angus, TE McAlindon, P Dieppe, B Rajagopalan, GK Radda

Journal article  |  1990  |  Proceedings of the National Academy of Sciences

The hyperuricemia responsible for the development of gouty arthritis results from a wide range of environmental factors and underl..

Review article: hypoxia and hepatic drug metabolism--clinical implications.

PW Angus, DJ Morgan, RA Smallwood

Journal article  |  1990  |  Alimentary Pharmacology & Therapeutics

Most major pathways of hepatic drug metabolism are dependent on oxygen. Hepatic mixed-function oxidases use oxygen directly as a s..

An aberration of fructose metabolism in familial gout identified by 31P magnetic resonance spectroscopy of the liver.

JE Seegmiller, RM Dixon, GJ Kemp, PW Angus, TE McAlindon, P Dieppe, B Rajagopalan, GK Radda

Journal article  |  1990  |  Transactions of the Association of American Physicians

A study of patients with alcoholic liver disease by 31P nuclear magnetic resonance spectroscopy.

PW Angus, RM Dixon, B Rajagopalan, NG Ryley, KJ Simpson, TJ Peters, DP Jewell, GK Radda

Journal article  |  1990  |  Clinical Science

1. Patients with a history of alcohol abuse were studied by 31P n.m.r. spectroscopy of the liver in vivo, and the results were rel..

OXYGEN DEPENDENCE OF OMEPRAZOLE CLEARANCE AND SULFONE AND SULFIDE METABOLITE FORMATION IN THE ISOLATED PERFUSED RAT-LIVER

PW ANGUS, GW MIHALY, DJ MORGAN, RA SMALLWOOD

Journal article  |  1989  |  Journal of Pharmacology and Experimental Therapeutics

OXYGEN DEPENDENCE OF SALBUTAMOL ELIMINATION BY THE ISOLATED PERFUSED RAT-LIVER

PW ANGUS, GW MIHALY, DJ MORGAN, RA SMALLWOOD

Journal article  |  1989  |  Biochemical Pharmacology

EFFECT OF WEEKEND THERAPY WITH OMEPRAZOLE ON BASAL AND STIMULATED ACID-SECRETION AND FASTING PLASMA GASTRIN IN DUODENAL-ULCER PATIENTS

EG HEWSON, ND YEOMANS, PW ANGUS, A SHULKES, CW BROOK, RB SEWELL, RA SMALLWOOD

Journal article  |  1988  |  Gut

SYNERGISTIC EFFECTS OF HYPOXIA AND FASTING ON HARMOL ELIMINATION IN THE ISOLATED PERFUSED RAT-LIVER

PW ANGUS, GW MIHALY, DJ MORGAN, RA SMALLWOOD

Journal article  |  1988  |  Biochemical Pharmacology

Hypoxia impairs conjugation and elimination of harmol in the isolated perfused rat liver.

PW Angus, GW Mihaly, DJ Morgan, RA Smallwood

Journal article  |  1987  |  Journal of Pharmacology and Experimental Therapeutics

Although studies in isolated hepatocytes have demonstrated that hypoxia adversely affects drug conjugation, the impact of hypoxia ..

High-performance liquid chromatographic analysis of harmol and its conjugated metabolites after enzyme hydrolysis in biological fluids.

MS Ching, GW Mihaly, PW Angus, JD Anderson, RA Smallwood

Journal article  |  1986  |  Journal of Chromatography B: Biomedical Sciences and Applications